BR9911482A - Composto, composição farmacêutica, uso do composto, e, processos para o tratamento ou profilaxia de doenças inflamatórias, e para a preparação de um composto - Google Patents

Composto, composição farmacêutica, uso do composto, e, processos para o tratamento ou profilaxia de doenças inflamatórias, e para a preparação de um composto

Info

Publication number
BR9911482A
BR9911482A BR9911482-8A BR9911482A BR9911482A BR 9911482 A BR9911482 A BR 9911482A BR 9911482 A BR9911482 A BR 9911482A BR 9911482 A BR9911482 A BR 9911482A
Authority
BR
Brazil
Prior art keywords
compound
processes
treatment
inflammatory diseases
prophylaxis
Prior art date
Application number
BR9911482-8A
Other languages
English (en)
Inventor
David George Allen
Chuen Chan
Richard Peter Charles Cousins
Brian Cox
Joanna Victoria Geden
Heather Hobbs
Suzanne Elaine Keeling
Alison Judith Redgrave
Thomas Davis Roper
Shiping Xie
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9813538.7A external-priority patent/GB9813538D0/en
Priority claimed from GBGB9909482.3A external-priority patent/GB9909482D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BR9911482A publication Critical patent/BR9911482A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06—Heterocyclic radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DO COMPOSTO, E, PROCESSOS PARA O TRATAMENTO OU PROFILAXIA DE DOENçAS INFLAMATóRIAS, E PARA A PREPARAçãO DE UM COMPOSTO". São providos, de acordo com a invenção, novos compostos de fórmula (1), em que R^ 1^, R^ 2^ e R^ 3^ são como definidos no relatório descritivo, processos para preparar os mesmos, formulações contendo os mesmos, e seu uso em terapia para o tratamento de doenças inflamatórias.
BR9911482-8A 1998-06-23 1999-06-23 Composto, composição farmacêutica, uso do composto, e, processos para o tratamento ou profilaxia de doenças inflamatórias, e para a preparação de um composto BR9911482A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9813538.7A GB9813538D0 (en) 1998-06-23 1998-06-23 Chemical compounds
GBGB9909482.3A GB9909482D0 (en) 1999-04-23 1999-04-23 2-(Purin-9-yl)-tetahydrofuran-3,4-diol derivatives
PCT/EP1999/004269 WO1999067265A1 (en) 1998-06-23 1999-06-23 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives

Publications (1)

Publication Number Publication Date
BR9911482A true BR9911482A (pt) 2002-01-22

Family

ID=26313917

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911482-8A BR9911482A (pt) 1998-06-23 1999-06-23 Composto, composição farmacêutica, uso do composto, e, processos para o tratamento ou profilaxia de doenças inflamatórias, e para a preparação de um composto

Country Status (27)

Country Link
US (1) US6495528B1 (pt)
EP (1) EP1090022B1 (pt)
JP (1) JP3933870B2 (pt)
KR (1) KR20010071591A (pt)
CN (1) CN1313861A (pt)
AP (1) AP2000002016A0 (pt)
AT (1) ATE246701T1 (pt)
AU (1) AU750462B2 (pt)
BR (1) BR9911482A (pt)
CA (1) CA2335809A1 (pt)
CZ (1) CZ20004868A3 (pt)
DE (1) DE69910213T2 (pt)
EA (1) EA200001224A1 (pt)
EE (1) EE200000768A (pt)
ES (1) ES2204139T3 (pt)
HR (1) HRP20000894A2 (pt)
HU (1) HUP0103025A3 (pt)
ID (1) ID29609A (pt)
IL (1) IL140396A0 (pt)
IS (1) IS5779A (pt)
NO (1) NO20006548L (pt)
NZ (1) NZ509030A (pt)
PL (1) PL345062A1 (pt)
SK (1) SK19542000A3 (pt)
TR (1) TR200100410T2 (pt)
WO (1) WO1999067265A1 (pt)
YU (1) YU81100A (pt)

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GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
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EP1903044A1 (en) 2006-09-14 2008-03-26 Novartis AG Adenosine Derivatives as A2A Receptor Agonists
AU2007302263A1 (en) 2006-09-29 2008-04-03 Novartis Ag Pyrazolopyrimidines as P13K lipid kinase inhibitors
MX2009004715A (es) 2006-10-30 2009-05-20 Novartis Ag Compuestos heterociclicos como agentes antiinflamatorios.
CA2711637A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
PL2391366T3 (pl) 2009-01-29 2013-04-30 Novartis Ag Podstawione benzimidazole do leczenia gwiaździaków
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
AU2010283806A1 (en) 2009-08-12 2012-03-01 Novartis Ag Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
NZ620020A (en) 2009-08-17 2015-06-26 Intellikine Llc Heterocyclic compounds and uses thereof
WO2011020861A1 (en) 2009-08-20 2011-02-24 Novartis Ag Heterocyclic oxime compounds
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
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WO2012116237A2 (en) 2011-02-23 2012-08-30 Intellikine, Llc Heterocyclic compounds and uses thereof
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Also Published As

Publication number Publication date
AU750462B2 (en) 2002-07-18
DE69910213T2 (de) 2004-07-01
TR200100410T2 (tr) 2001-06-21
IL140396A0 (en) 2002-02-10
KR20010071591A (ko) 2001-07-28
CA2335809A1 (en) 1999-12-29
EP1090022B1 (en) 2003-08-06
HUP0103025A3 (en) 2002-04-29
ID29609A (id) 2001-09-06
AU4774499A (en) 2000-01-10
NO20006548L (no) 2001-02-22
JP3933870B2 (ja) 2007-06-20
NO20006548D0 (no) 2000-12-21
DE69910213D1 (de) 2003-09-11
SK19542000A3 (sk) 2001-09-11
HUP0103025A2 (hu) 2001-12-28
CN1313861A (zh) 2001-09-19
YU81100A (sh) 2003-10-31
ES2204139T3 (es) 2004-04-16
AP2000002016A0 (en) 2000-12-31
HRP20000894A2 (en) 2001-12-31
PL345062A1 (en) 2001-11-19
CZ20004868A3 (cs) 2001-08-15
IS5779A (is) 2000-12-19
EP1090022A1 (en) 2001-04-11
ATE246701T1 (de) 2003-08-15
WO1999067265A1 (en) 1999-12-29
US6495528B1 (en) 2002-12-17
NZ509030A (en) 2003-07-25
EE200000768A (et) 2002-04-15
JP2002518512A (ja) 2002-06-25
EA200001224A1 (ru) 2001-08-27

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