FR2687678B1 - Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. - Google Patents

Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.

Info

Publication number
FR2687678B1
FR2687678B1 FR9201113A FR9201113A FR2687678B1 FR 2687678 B1 FR2687678 B1 FR 2687678B1 FR 9201113 A FR9201113 A FR 9201113A FR 9201113 A FR9201113 A FR 9201113A FR 2687678 B1 FR2687678 B1 FR 2687678B1
Authority
FR
France
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
adenosine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9201113A
Other languages
English (en)
Other versions
FR2687678A1 (fr
Inventor
Nicole Bru-Magniez
Timur Gungor
Jean-Marie Teulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNION PHARMA SCIENT APPL
Original Assignee
UNION PHARMA SCIENT APPL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNION PHARMA SCIENT APPL filed Critical UNION PHARMA SCIENT APPL
Priority to FR9201113A priority Critical patent/FR2687678B1/fr
Priority to US07/844,778 priority patent/US5219839A/en
Priority to AU35030/93A priority patent/AU3503093A/en
Priority to PCT/FR1993/000049 priority patent/WO1993015100A1/fr
Publication of FR2687678A1 publication Critical patent/FR2687678A1/fr
Application granted granted Critical
Publication of FR2687678B1 publication Critical patent/FR2687678B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9201113A 1992-01-31 1992-01-31 Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. Expired - Fee Related FR2687678B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR9201113A FR2687678B1 (fr) 1992-01-31 1992-01-31 Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.
US07/844,778 US5219839A (en) 1992-01-31 1992-03-02 Adenosine derivatives, their methods of preparation and pharmaceutical compositions in which they are present
AU35030/93A AU3503093A (en) 1992-01-31 1993-01-19 Novel adenosine derivatives, their preparation methods and pharmaceutical compositions containing same
PCT/FR1993/000049 WO1993015100A1 (fr) 1992-01-31 1993-01-19 Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9201113A FR2687678B1 (fr) 1992-01-31 1992-01-31 Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.

Publications (2)

Publication Number Publication Date
FR2687678A1 FR2687678A1 (fr) 1993-08-27
FR2687678B1 true FR2687678B1 (fr) 1995-03-31

Family

ID=9426226

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9201113A Expired - Fee Related FR2687678B1 (fr) 1992-01-31 1992-01-31 Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.

Country Status (4)

Country Link
US (1) US5219839A (fr)
AU (1) AU3503093A (fr)
FR (1) FR2687678B1 (fr)
WO (1) WO1993015100A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
US6495528B1 (en) 1998-06-23 2002-12-17 Smithkline Beecham Corporation 2-(Purin -9-yl)-tetrahydrofuran-3,4-diol derivatives
US6784165B1 (en) * 1999-11-23 2004-08-31 Aderis Pharmaceuticals, Inc. Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines
AU2004238217A1 (en) * 2003-04-24 2004-11-25 Aderis Pharmaceuticals, Inc. Method of treating atrial fibrillation or atrial flutter
US20050118262A1 (en) * 2003-09-17 2005-06-02 Jack Aurora Controlled release formulation
PE20060272A1 (es) * 2004-05-24 2006-05-22 Glaxo Group Ltd (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
CN2736752Y (zh) * 2004-07-30 2005-10-26 北京博奥生物芯片有限责任公司 一种用于提取药物残留的样品制备仪
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
WO2009032057A2 (fr) 2007-08-29 2009-03-12 Adam Lubin Procédé pour la thérapie sélective d'une maladie
CN107353228A (zh) * 2016-12-27 2017-11-17 辅仁药业集团熙德隆肿瘤药品有限公司 一种琥珀酸西苯唑啉中间体的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
CA1239397A (fr) * 1983-08-01 1988-07-19 James A. Bristol Adenosines substituee en position n.sup.6
US5310731A (en) * 1984-06-28 1994-05-10 Whitby Research, Inc. N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
US4738954A (en) * 1985-11-06 1988-04-19 Warner-Lambert Company Novel N6 -substituted-5'-oxidized adenosine analogs
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
JPH0696534B2 (ja) * 1986-04-25 1994-11-30 ヘキストジヤパン株式会社 抗痴呆剤
AU8274187A (en) * 1986-10-31 1988-05-25 Warner-Lambert Company Heteroaromatic derivatives of adenosine
WO1988003147A1 (fr) * 1986-10-31 1988-05-05 Warner-Lambert Company Adenosines a substitution n6 selectionees ayant une activite de liaison a2 selective
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
CA2028002A1 (fr) * 1989-10-19 1991-04-20 Daniel P. Becker Methode de traitement des troubles de la motilite gastro-intestinale
US5055569A (en) * 1989-10-19 1991-10-08 G. D. Searle & Co. N-(6)-substituted adenosine compounds

Also Published As

Publication number Publication date
FR2687678A1 (fr) 1993-08-27
US5219839A (en) 1993-06-15
AU3503093A (en) 1993-09-01
WO1993015100A1 (fr) 1993-08-05

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Legal Events

Date Code Title Description
ST Notification of lapse