ID29609A - Turunan 2-(purin-9-il)-tetrahidrofuran-3,4-diol - Google Patents
Turunan 2-(purin-9-il)-tetrahidrofuran-3,4-diolInfo
- Publication number
- ID29609A ID29609A IDW20010189D ID20010189D ID29609A ID 29609 A ID29609 A ID 29609A ID W20010189 D IDW20010189 D ID W20010189D ID 20010189 D ID20010189 D ID 20010189D ID 29609 A ID29609 A ID 29609A
- Authority
- ID
- Indonesia
- Prior art keywords
- durunan
- tetrahidrofuran
- purin
- diol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/06—Heterocyclic radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9813538.7A GB9813538D0 (en) | 1998-06-23 | 1998-06-23 | Chemical compounds |
GBGB9909482.3A GB9909482D0 (en) | 1999-04-23 | 1999-04-23 | 2-(Purin-9-yl)-tetahydrofuran-3,4-diol derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ID29609A true ID29609A (id) | 2001-09-06 |
Family
ID=26313917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20010189D ID29609A (id) | 1998-06-23 | 1999-06-23 | Turunan 2-(purin-9-il)-tetrahidrofuran-3,4-diol |
Country Status (27)
Country | Link |
---|---|
US (1) | US6495528B1 (id) |
EP (1) | EP1090022B1 (id) |
JP (1) | JP3933870B2 (id) |
KR (1) | KR20010071591A (id) |
CN (1) | CN1313861A (id) |
AP (1) | AP2000002016A0 (id) |
AT (1) | ATE246701T1 (id) |
AU (1) | AU750462B2 (id) |
BR (1) | BR9911482A (id) |
CA (1) | CA2335809A1 (id) |
CZ (1) | CZ20004868A3 (id) |
DE (1) | DE69910213T2 (id) |
EA (1) | EA200001224A1 (id) |
EE (1) | EE200000768A (id) |
ES (1) | ES2204139T3 (id) |
HR (1) | HRP20000894A2 (id) |
HU (1) | HUP0103025A3 (id) |
ID (1) | ID29609A (id) |
IL (1) | IL140396A0 (id) |
IS (1) | IS5779A (id) |
NO (1) | NO20006548L (id) |
NZ (1) | NZ509030A (id) |
PL (1) | PL345062A1 (id) |
SK (1) | SK19542000A3 (id) |
TR (1) | TR200100410T2 (id) |
WO (1) | WO1999067265A1 (id) |
YU (1) | YU81100A (id) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6514949B1 (en) | 1994-07-11 | 2003-02-04 | University Of Virginia Patent Foundation | Method compositions for treating the inflammatory response |
YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
CO4990969A1 (es) * | 1998-02-14 | 2000-12-26 | Glaxo Group Ltd | Derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol |
US6232297B1 (en) | 1999-02-01 | 2001-05-15 | University Of Virginia Patent Foundation | Methods and compositions for treating inflammatory response |
US7427606B2 (en) | 1999-02-01 | 2008-09-23 | University Of Virginia Patent Foundation | Method to reduce inflammatory response in transplanted tissue |
US7378400B2 (en) | 1999-02-01 | 2008-05-27 | University Of Virginia Patent Foundation | Method to reduce an inflammatory response from arthritis |
ATE284712T1 (de) * | 2000-04-26 | 2005-01-15 | Eisai Co Ltd | Medizinische zusammensetzungen zur förderung der aktivierung der eingeweide |
GB0022695D0 (en) | 2000-09-15 | 2000-11-01 | Pfizer Ltd | Purine Derivatives |
GB0104555D0 (en) * | 2001-02-23 | 2001-04-11 | Glaxo Group Ltd | New Therapeutic method |
NZ532062A (en) | 2001-10-01 | 2006-09-29 | Univ Virginia | 2-propynyl adenosine analogues having A2 adenosine recepter agonist activity and compositions thereof to treat inflammatory responses |
GB0206655D0 (en) * | 2002-03-21 | 2002-05-01 | Glaxo Group Ltd | Novel process |
TW200519106A (en) | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
TWI346109B (en) * | 2004-04-30 | 2011-08-01 | Otsuka Pharma Co Ltd | 4-amino-5-cyanopyrimidine derivatives |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
WO2006028618A1 (en) | 2004-08-02 | 2006-03-16 | University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity |
US7442687B2 (en) | 2004-08-02 | 2008-10-28 | The University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs having A2A agonist activity |
WO2006015357A2 (en) | 2004-08-02 | 2006-02-09 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity |
GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
GB0500785D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
GB0505219D0 (en) * | 2005-03-14 | 2005-04-20 | Novartis Ag | Organic compounds |
GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
GB0514809D0 (en) * | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
AR058104A1 (es) | 2005-10-21 | 2008-01-23 | Novartis Ag | Compuestos organicos |
GB0523845D0 (en) * | 2005-11-23 | 2006-01-04 | Glaxo Group Ltd | Novel salts |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
PT2322525E (pt) | 2006-04-21 | 2013-12-26 | Novartis Ag | Derivados de purina para utilização como agonistas do recetor de adenosina a2a |
GB0607950D0 (en) | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
EP1889846A1 (en) * | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
EP1903044A1 (en) | 2006-09-14 | 2008-03-26 | Novartis AG | Adenosine Derivatives as A2A Receptor Agonists |
JP2010504933A (ja) | 2006-09-29 | 2010-02-18 | ノバルティス アーゲー | Pi3k脂質キナーゼ阻害剤としてのピラゾロピリミジン |
EP2089393A1 (en) | 2006-10-30 | 2009-08-19 | Novartis AG | Heterocyclic compounds as antiinflammatory agents |
PL2231642T3 (pl) | 2008-01-11 | 2014-04-30 | Novartis Ag | Pirymidyny jako inhibitory kinazy |
US20110281917A1 (en) | 2009-01-29 | 2011-11-17 | Darrin Stuart | Substituted Benzimidazoles for the Treatment of Astrocytomas |
US8389526B2 (en) | 2009-08-07 | 2013-03-05 | Novartis Ag | 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives |
AU2010283806A1 (en) | 2009-08-12 | 2012-03-01 | Novartis Ag | Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation |
SG178454A1 (en) | 2009-08-17 | 2012-03-29 | Intellikine Inc | Heterocyclic compounds and uses thereof |
JP5775871B2 (ja) | 2009-08-20 | 2015-09-09 | ノバルティス アーゲー | ヘテロ環式オキシム化合物 |
UY33597A (es) | 2010-09-09 | 2012-04-30 | Irm Llc | Compuestos y composiciones como inhibidores de la trk |
WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
WO2012107500A1 (en) | 2011-02-10 | 2012-08-16 | Novartis Ag | [1, 2, 4] triazolo [4, 3 -b] pyridazine compounds as inhibitors of the c-met tyrosine kinase |
WO2012116237A2 (en) | 2011-02-23 | 2012-08-30 | Intellikine, Llc | Heterocyclic compounds and uses thereof |
WO2012116217A1 (en) | 2011-02-25 | 2012-08-30 | Irm Llc | Compounds and compositions as trk inhibitors |
JP5957526B2 (ja) | 2011-09-15 | 2016-07-27 | ノバルティス アーゲー | チロシンキナーゼとしての6−置換3−(キノリン−6−イルチオ)−[1,2,4]トリアゾロ[4,3−a]ピラジン |
WO2013078440A2 (en) | 2011-11-23 | 2013-05-30 | Intellikine, Llc | Enhanced treatment regimens using mtor inhibitors |
CN110507654A (zh) | 2012-04-03 | 2019-11-29 | 诺华有限公司 | 有酪氨酸激酶抑制剂的组合产品和其应用 |
JP2016512835A (ja) | 2013-03-15 | 2016-05-09 | インテリカイン, エルエルシー | キナーゼ阻害剤の組み合わせ及びそれらの使用 |
TW201605450A (zh) | 2013-12-03 | 2016-02-16 | 諾華公司 | Mdm2抑制劑與BRAF抑制劑之組合及其用途 |
WO2016011658A1 (en) | 2014-07-25 | 2016-01-28 | Novartis Ag | Combination therapy |
US10195208B2 (en) | 2014-07-31 | 2019-02-05 | Novartis Ag | Combination therapy |
CN106632572B (zh) * | 2016-12-16 | 2018-08-14 | 中国科学院成都生物研究所 | 一种黄芪甲苷衍生物及其制备方法和应用 |
TW202140550A (zh) | 2020-01-29 | 2021-11-01 | 瑞士商諾華公司 | 使用抗tslp抗體治療炎性或阻塞性氣道疾病之方法 |
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LU87181A1 (fr) | 1987-04-06 | 1988-11-17 | Sandoz Sa | Nouveaux derives de l'acide furannuronique,leur preparation et leur utilisation comme medicaments |
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FR2685918B1 (fr) | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
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WO1994002497A1 (en) | 1992-07-15 | 1994-02-03 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Sulfo-derivatives of adenosine |
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GB9414208D0 (en) | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
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TW528755B (en) * | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
ZA9810766B (en) | 1997-11-28 | 1999-05-25 | Mochida Pharm Co Ltd | Novel compounds having cgmp-pde inhibitory activity |
YU44900A (sh) * | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
CO4990969A1 (es) * | 1998-02-14 | 2000-12-26 | Glaxo Group Ltd | Derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol |
-
1999
- 1999-06-23 US US09/720,390 patent/US6495528B1/en not_active Expired - Fee Related
- 1999-06-23 YU YU81100A patent/YU81100A/sh unknown
- 1999-06-23 AP APAP/P/2000/002016A patent/AP2000002016A0/en unknown
- 1999-06-23 CN CN99809892A patent/CN1313861A/zh active Pending
- 1999-06-23 KR KR1020007014720A patent/KR20010071591A/ko not_active Application Discontinuation
- 1999-06-23 CA CA002335809A patent/CA2335809A1/en not_active Abandoned
- 1999-06-23 ES ES99931113T patent/ES2204139T3/es not_active Expired - Lifetime
- 1999-06-23 DE DE69910213T patent/DE69910213T2/de not_active Expired - Lifetime
- 1999-06-23 NZ NZ509030A patent/NZ509030A/en not_active Application Discontinuation
- 1999-06-23 IL IL14039699A patent/IL140396A0/xx unknown
- 1999-06-23 JP JP2000555916A patent/JP3933870B2/ja not_active Expired - Fee Related
- 1999-06-23 EA EA200001224A patent/EA200001224A1/ru unknown
- 1999-06-23 TR TR2001/00410T patent/TR200100410T2/xx unknown
- 1999-06-23 AU AU47744/99A patent/AU750462B2/en not_active Ceased
- 1999-06-23 ID IDW20010189D patent/ID29609A/id unknown
- 1999-06-23 EE EEP200000768A patent/EE200000768A/xx unknown
- 1999-06-23 PL PL99345062A patent/PL345062A1/xx unknown
- 1999-06-23 WO PCT/EP1999/004269 patent/WO1999067265A1/en not_active Application Discontinuation
- 1999-06-23 AT AT99931113T patent/ATE246701T1/de not_active IP Right Cessation
- 1999-06-23 BR BR9911482-8A patent/BR9911482A/pt not_active IP Right Cessation
- 1999-06-23 CZ CZ20004868A patent/CZ20004868A3/cs unknown
- 1999-06-23 EP EP99931113A patent/EP1090022B1/en not_active Expired - Lifetime
- 1999-06-23 HU HU0103025A patent/HUP0103025A3/hu unknown
- 1999-06-23 SK SK1954-2000A patent/SK19542000A3/sk unknown
-
2000
- 2000-12-19 IS IS5779A patent/IS5779A/is unknown
- 2000-12-21 HR HR20000894A patent/HRP20000894A2/hr not_active Application Discontinuation
- 2000-12-21 NO NO20006548A patent/NO20006548L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EE200000768A (et) | 2002-04-15 |
HUP0103025A3 (en) | 2002-04-29 |
IS5779A (is) | 2000-12-19 |
BR9911482A (pt) | 2002-01-22 |
DE69910213D1 (de) | 2003-09-11 |
AU4774499A (en) | 2000-01-10 |
CN1313861A (zh) | 2001-09-19 |
SK19542000A3 (sk) | 2001-09-11 |
AU750462B2 (en) | 2002-07-18 |
WO1999067265A1 (en) | 1999-12-29 |
US6495528B1 (en) | 2002-12-17 |
JP2002518512A (ja) | 2002-06-25 |
HUP0103025A2 (hu) | 2001-12-28 |
DE69910213T2 (de) | 2004-07-01 |
NO20006548D0 (no) | 2000-12-21 |
JP3933870B2 (ja) | 2007-06-20 |
NO20006548L (no) | 2001-02-22 |
EA200001224A1 (ru) | 2001-08-27 |
CA2335809A1 (en) | 1999-12-29 |
IL140396A0 (en) | 2002-02-10 |
HRP20000894A2 (en) | 2001-12-31 |
EP1090022B1 (en) | 2003-08-06 |
EP1090022A1 (en) | 2001-04-11 |
AP2000002016A0 (en) | 2000-12-31 |
NZ509030A (en) | 2003-07-25 |
YU81100A (sh) | 2003-10-31 |
CZ20004868A3 (cs) | 2001-08-15 |
KR20010071591A (ko) | 2001-07-28 |
ES2204139T3 (es) | 2004-04-16 |
PL345062A1 (en) | 2001-11-19 |
ATE246701T1 (de) | 2003-08-15 |
TR200100410T2 (tr) | 2001-06-21 |
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