ID23761A - Trisiklik tersubstitusi - Google Patents

Trisiklik tersubstitusi

Info

Publication number
ID23761A
ID23761A IDP990341D ID990341D ID23761A ID 23761 A ID23761 A ID 23761A ID P990341 D IDP990341 D ID P990341D ID 990341 D ID990341 D ID 990341D ID 23761 A ID23761 A ID 23761A
Authority
ID
Indonesia
Prior art keywords
trisiclic
substituted
substituted trisiclic
Prior art date
Application number
IDP990341D
Other languages
English (en)
Inventor
Nicholas James Bach
Jolie Anne Bastian
Richard Waltz
Gary Alan Hite
Michael Dean Kinnicck
Edward David Michelich
John Michael Morin Jr
Daniel Jon Sall
Robert Theodore Vasileff
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID23761A publication Critical patent/ID23761A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDP990341D 1998-04-17 1999-04-15 Trisiklik tersubstitusi ID23761A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6232898A 1998-04-17 1998-04-17

Publications (1)

Publication Number Publication Date
ID23761A true ID23761A (id) 2000-05-11

Family

ID=22041763

Family Applications (2)

Application Number Title Priority Date Filing Date
IDP990341D ID23761A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi
IDP990340D ID23287A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi

Family Applications After (1)

Application Number Title Priority Date Filing Date
IDP990340D ID23287A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi

Country Status (30)

Country Link
EP (2) EP0950657B1 (id)
JP (2) JPH11322713A (id)
KR (2) KR19990083232A (id)
CN (1) CN1149193C (id)
AR (2) AR018186A1 (id)
AT (2) ATE268756T1 (id)
AU (2) AU753436B2 (id)
BR (2) BR9902365A (id)
CA (2) CA2269246C (id)
CO (2) CO5011054A1 (id)
CZ (2) CZ137099A3 (id)
DE (2) DE69917833T2 (id)
DK (1) DK0950657T3 (id)
DZ (1) DZ2769A1 (id)
EA (2) EA002816B1 (id)
ES (2) ES2226286T3 (id)
HU (2) HUP9901220A3 (id)
ID (2) ID23761A (id)
IL (2) IL129485A0 (id)
NO (2) NO314400B1 (id)
NZ (3) NZ507564A (id)
PE (2) PE20000476A1 (id)
PL (2) PL332566A1 (id)
PT (1) PT950657E (id)
SG (2) SG81976A1 (id)
SI (1) SI0950657T1 (id)
TR (2) TR199900853A3 (id)
TW (1) TWI238160B (id)
YU (2) YU18999A (id)
ZA (2) ZA992772B (id)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009978A1 (en) * 1997-08-28 1999-03-04 Eli Lilly And Company Method for treatment of non-rheumatoid athritis
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
EP1214041A2 (en) * 1998-12-21 2002-06-19 Eli Lilly And Company Combination therapy for the treatment of sepsis
US6706752B1 (en) 1999-07-19 2004-03-16 Eli Lilly And Company sPLA2 inhibitors
AU5873400A (en) * 1999-07-19 2001-02-05 Eli Lilly And Company spla2 inhibitors
EP1300159B1 (en) * 2000-06-29 2007-10-10 Anthera Pharmaceuticals, Inc. Remedies for cancer
AU2001267825A1 (en) 2000-06-29 2002-01-08 Shionogi And Co., Ltd. Remedies for cirrhosis
US20040102442A1 (en) * 2000-06-29 2004-05-27 Kohji Hanasaki Remedies for alzheimer's disease
CA2413582A1 (en) * 2000-07-14 2002-01-24 Eli Lilly And Company Use of a spla2 inhibitor for the treatment of sepsis
EP1345898A2 (en) * 2000-12-18 2003-09-24 Eli Lilly And Company Teracyclic carbazole derivates and their use as spla2 inhibitors
WO2002079154A1 (en) * 2001-03-28 2002-10-10 Eli Lilly And Company Substituted carbazoles as inhibitors of spla2
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
DE10249055A1 (de) 2002-10-22 2004-05-06 Bayer Cropscience Ag 2-Phenyl-2-substituierte-1,3-diketone
JO3598B1 (ar) 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
EP1988098A1 (en) * 2007-04-27 2008-11-05 AEterna Zentaris GmbH Novel Tetrahydrocarbazole Derivatives as Ligands of G-protein Coupled Receptors
EP2256105B1 (en) 2008-03-26 2013-12-04 Daiichi Sankyo Company, Limited Novel tetrahydroisoquinoline derivative
WO2009126691A1 (en) 2008-04-09 2009-10-15 Infinity Pharmaceuticals, Inc Inhibitors of fatty acid amide hydrolase
EP2379538A4 (en) * 2009-01-22 2013-01-02 Orchid Res Lab Ltd HETEROCYCLIC COMPOUNDS AS A PHOSOPHODIESTERASE HEMMER
CA2757622A1 (en) 2009-04-07 2010-10-14 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
AU2010234445A1 (en) 2009-04-07 2011-11-03 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
MX361011B (es) 2010-02-03 2018-11-26 Infinity Pharmaceuticals Inc Inhibidores de amida hidrolasa de ácido graso.
AR088377A1 (es) 2011-10-20 2014-05-28 Siena Biotech Spa Proceso para la preparacion de 6-cloro-2,3,4,9-tetrahidro-1h-carbazol-1-carboxamida y compuestos intermedios de esta
CN102816107B (zh) * 2012-08-20 2015-06-03 东南大学 咔唑衍生物及其制备方法与用途
BR112015012138A2 (pt) 2012-11-30 2017-07-11 Ge Healthcare Ltd composição, método para obtenção de uma composição, método de formação de imagem in vivo, e, kit
KR20150088803A (ko) 2012-11-30 2015-08-03 지이 헬쓰케어 리미티드 트리시클릭 인돌을 생성하는 아연 할라이드 매개 고리화 방법
EP3248230B1 (de) * 2015-01-20 2020-05-06 cynora GmbH Verwendung organischer moleküle in optoelektronischen bauelementen
CN108707104A (zh) * 2018-08-07 2018-10-26 北京恒信卓元科技有限公司 2-氯-1h-咔唑-1,4(9h)-二酮的合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579534A (en) * 1969-05-09 1971-05-18 American Cyanamid Co Tetrahydrocarbazolecarboxylates
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
US3939177A (en) * 1972-11-22 1976-02-17 Sterling Drug Inc. 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
US5420289A (en) * 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
WO1993001169A2 (en) * 1991-07-05 1993-01-21 Merck Sharp & Dohme Limited Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
DE69610793T2 (de) * 1995-06-23 2001-05-03 Eli Lilly And Co., Indianapolis 6-Subsitituierte-1,2,3,4-tetrahydro-9H-Carbazole und 7-substituierte-1OH-Cyclohepta(7,6-B)-Indole
BR9612347A (pt) * 1995-12-13 1999-07-13 Lilly Co Eli Naftil acetamidas como inibidores de spla2
CZ136899A3 (cs) * 1996-10-30 1999-09-15 Eli Lilly And Company Substituované tricyklické sloučeniny
WO1999016453A1 (en) * 1997-09-26 1999-04-08 Eli Lilly And Company Method for the treatment of cystic fibrosis
CA2310250A1 (en) * 1997-11-14 1999-05-27 August Masaru Watanabe Treatment for alzheimer's disease
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.

Also Published As

Publication number Publication date
EA199900301A3 (ru) 2000-04-24
EP0950657A2 (en) 1999-10-20
KR19990083233A (ko) 1999-11-25
EP0950657B1 (en) 2004-07-14
EA199900303A2 (ru) 1999-10-28
EP0950657A3 (en) 2001-08-16
EP0952149B1 (en) 2004-06-09
CA2269262A1 (en) 1999-10-17
KR100586761B1 (ko) 2006-06-08
DK0950657T3 (da) 2004-11-22
ES2222663T3 (es) 2005-02-01
SG81976A1 (en) 2001-07-24
YU18999A (sh) 2002-08-12
AU753436B2 (en) 2002-10-17
PL332565A1 (en) 1999-10-25
BR9902365A (pt) 2001-04-24
CN1149193C (zh) 2004-05-12
TR199900843A2 (xx) 2000-02-21
NZ335253A (en) 2000-11-24
HU9901221D0 (en) 1999-06-28
HU9901221A (hu) 2000-04-28
BR9901279A (pt) 2000-05-02
SI0950657T1 (en) 2005-02-28
PL332566A1 (en) 1999-10-25
PT950657E (pt) 2004-11-30
NO991821D0 (no) 1999-04-16
EA199900301A2 (ru) 1999-10-28
ZA992772B (en) 2002-07-16
NZ335251A (en) 2000-11-24
CO5031247A1 (es) 2001-04-27
CO5011054A1 (es) 2001-02-28
KR19990083232A (ko) 1999-11-25
DE69918590T2 (de) 2005-07-21
EA002347B1 (ru) 2002-04-25
DE69918590D1 (de) 2004-08-19
NO314400B1 (no) 2003-03-17
JP2000026416A (ja) 2000-01-25
NO991822D0 (no) 1999-04-16
AU2381999A (en) 1999-10-28
NO312240B1 (no) 2002-04-15
CA2269246C (en) 2009-08-25
ZA992771B (en) 2002-04-18
IL129483A0 (en) 2000-02-29
ES2226286T3 (es) 2005-03-16
AU2381799A (en) 1999-10-28
AU753547B2 (en) 2002-10-24
AR018186A1 (es) 2001-10-31
JP4435330B2 (ja) 2010-03-17
TWI238160B (en) 2005-08-21
ATE271037T1 (de) 2004-07-15
YU19199A (sh) 2002-08-12
HUP9901221A3 (en) 2001-11-28
TR199900853A2 (xx) 1999-11-22
CZ136999A3 (cs) 1999-11-17
DE69917833T2 (de) 2005-07-14
NO991821L (no) 1999-10-18
NZ507564A (en) 2002-10-25
HU9901220D0 (en) 1999-06-28
JPH11322713A (ja) 1999-11-24
AR018593A1 (es) 2001-11-28
IL129485A0 (en) 2000-02-29
SG81977A1 (en) 2001-07-24
HUP9901220A3 (en) 2001-11-28
HU9901220A (hu) 2000-04-28
EP0952149A3 (en) 2001-08-16
EA199900303A3 (ru) 2000-04-24
EP0952149A2 (en) 1999-10-27
CZ137099A3 (cs) 1999-11-17
DZ2769A1 (fr) 2003-12-01
TR199900853A3 (tr) 1999-11-22
DE69917833D1 (de) 2004-07-15
CA2269246A1 (en) 1999-10-17
ID23287A (id) 2000-04-05
EA002816B1 (ru) 2002-10-31
NO991822L (no) 1999-10-18
PE20000432A1 (es) 2000-05-23
PE20000476A1 (es) 2000-06-02
CN1253948A (zh) 2000-05-24
ATE268756T1 (de) 2004-06-15

Similar Documents

Publication Publication Date Title
DE59914158D1 (de) Metallocenmonohalogenide
DE69936168D1 (de) Mehrfachprobeninlassmassenspektrometer
DE59911453D1 (de) Aktivkohlefilter
DE69808145D1 (de) Tintenbehälternachfüllsystem
DE59912371D1 (de) Gleitschalungsfertiger
DE59902874D1 (de) Buchsenkontakt
DE59901560D1 (de) Retrograder tibianagel
ITMI992520A0 (it) Macrolidi
DE69921320D1 (de) Turbinenstatorschaufel
DE69812868D1 (de) Flanschreformierungsanlage
DE59907306D1 (de) Fadenchangierung
ID23287A (id) Trisiklik tersubstitusi
DE59906931D1 (de) Exzenterzahnradgetriebe
DE59911683D1 (de) Fahrzeugschliessanlage
DE69811890D1 (de) Einzellenkalorimeter
DE59908968D1 (de) Benzoylpyridazine
DE59903966D1 (de) Exzenterzahnradgetriebe
ID23219A (id) Trisiklik tersubstitusi
DE59908769D1 (de) N-arylsulfonyl-aminosäure-omega-amide
DE69820261D1 (de) Steuerventilanordnnung
DE59903106D1 (de) Tripode-gleichlaufdrehgelenk
DE59901046D1 (de) Methylcyclotetradec-5-en-1-one
DE69809804D1 (de) Notlaufgeländereifen
DE59908057D1 (de) Underdruckhandhabungseinrichung
DE59807217D1 (de) Nadellager