DK1149106T3 - 4,5-azolo-oxindoler - Google Patents

4,5-azolo-oxindoler

Info

Publication number
DK1149106T3
DK1149106T3 DK99964543T DK99964543T DK1149106T3 DK 1149106 T3 DK1149106 T3 DK 1149106T3 DK 99964543 T DK99964543 T DK 99964543T DK 99964543 T DK99964543 T DK 99964543T DK 1149106 T3 DK1149106 T3 DK 1149106T3
Authority
DK
Denmark
Prior art keywords
oxindoles
azolo
Prior art date
Application number
DK99964543T
Other languages
English (en)
Inventor
Kin-Chun Luk
Christophe Michoud
Steven Gregory Mischke
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1149106T3 publication Critical patent/DK1149106T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/04Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups one >CH- group, e.g. cyanines, isocyanines, pseudocyanines

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99964543T 1998-12-17 1999-12-10 4,5-azolo-oxindoler DK1149106T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11261198P 1998-12-17 1998-12-17
PCT/EP1999/009779 WO2000035920A2 (en) 1998-12-17 1999-12-10 4,5-azolo-oxindoles

Publications (1)

Publication Number Publication Date
DK1149106T3 true DK1149106T3 (da) 2003-07-14

Family

ID=22344875

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99964543T DK1149106T3 (da) 1998-12-17 1999-12-10 4,5-azolo-oxindoler

Country Status (18)

Country Link
EP (1) EP1149106B1 (da)
JP (1) JP2002532502A (da)
KR (2) KR100723854B1 (da)
CN (1) CN1159315C (da)
AR (1) AR021693A1 (da)
AT (1) ATE234839T1 (da)
AU (1) AU770060B2 (da)
BR (1) BR9916216A (da)
CA (1) CA2354852C (da)
DE (1) DE69906149T2 (da)
DK (1) DK1149106T3 (da)
ES (1) ES2192878T3 (da)
PE (1) PE20001329A1 (da)
PT (1) PT1149106E (da)
TR (1) TR200101745T2 (da)
UY (1) UY25855A1 (da)
WO (1) WO2000035920A2 (da)
ZA (1) ZA200104269B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR042586A1 (es) * 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
AU2004284084A1 (en) 2003-10-24 2005-05-06 Schering Aktiengesellschaft Indolinone derivatives and their use in treating disease-states such as cancer
JP2008535876A (ja) * 2005-04-14 2008-09-04 エフ.ホフマン−ラ ロシュ アーゲー アミノピラゾール誘導体、これらの製造、及び医薬製剤としての使用。
BRPI0613042A2 (pt) 2005-07-15 2010-12-14 Serono Lab inibidores de jnk para o tratamento de endometriose
KR20080044836A (ko) 2005-07-15 2008-05-21 라보라뚜와르 세로노 에스. 에이. 자궁내막증 치료용 jnk 억제제
US9051263B2 (en) 2010-08-25 2015-06-09 Pacific Biosciences Of California, Inc. Functionalized cyanine dyes (PEG)
US10458915B2 (en) 2012-05-18 2019-10-29 Pacific Biosciences Of California, Inc. Heteroarylcyanine dyes
US9315864B2 (en) 2012-05-18 2016-04-19 Pacific Biosciences Of California, Inc. Heteroarylcyanine dyes with sulfonic acid substituents
KR101668074B1 (ko) 2015-02-12 2016-10-21 전북대학교산학협력단 Pkr 저해제를 유효성분으로 포함하는 기관지 천식의 예방 또는 치료용 조성물
US12097261B2 (en) 2021-05-07 2024-09-24 Kymera Therapeutics, Inc. CDK2 degraders and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE292623T1 (de) * 1997-05-07 2005-04-15 Sugen Inc 2-indolinonderivate als modulatoren der proteinkinase-ativität
GB9718913D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives

Also Published As

Publication number Publication date
ES2192878T3 (es) 2003-10-16
KR100685192B1 (ko) 2007-02-22
UY25855A1 (es) 2001-08-27
AU770060B2 (en) 2004-02-12
BR9916216A (pt) 2001-09-11
EP1149106B1 (en) 2003-03-19
AR021693A1 (es) 2002-07-31
PT1149106E (pt) 2003-06-30
EP1149106A2 (en) 2001-10-31
JP2002532502A (ja) 2002-10-02
TR200101745T2 (tr) 2002-05-21
WO2000035920A2 (en) 2000-06-22
DE69906149D1 (de) 2003-04-24
KR20060109360A (ko) 2006-10-19
CN1330654A (zh) 2002-01-09
PE20001329A1 (es) 2000-12-11
KR100723854B1 (ko) 2007-05-31
CA2354852A1 (en) 2000-06-22
ATE234839T1 (de) 2003-04-15
DE69906149T2 (de) 2003-12-18
CA2354852C (en) 2008-09-23
CN1159315C (zh) 2004-07-28
AU3037200A (en) 2000-07-03
WO2000035920A3 (en) 2000-11-23
ZA200104269B (en) 2002-08-26
KR20010080768A (ko) 2001-08-22

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