DE60025958D1 - 14,15-beta-methylen substituierte androgene - Google Patents

14,15-beta-methylen substituierte androgene

Info

Publication number
DE60025958D1
DE60025958D1 DE60025958T DE60025958T DE60025958D1 DE 60025958 D1 DE60025958 D1 DE 60025958D1 DE 60025958 T DE60025958 T DE 60025958T DE 60025958 T DE60025958 T DE 60025958T DE 60025958 D1 DE60025958 D1 DE 60025958D1
Authority
DE
Germany
Prior art keywords
androgene
beta
methylene substituted
methylene
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60025958T
Other languages
English (en)
Other versions
DE60025958T2 (de
Inventor
Dirk Leysen
Der Louw Jaap Van
Bursi Roberta Buma
Gooyer Evert De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE60025958D1 publication Critical patent/DE60025958D1/de
Application granted granted Critical
Publication of DE60025958T2 publication Critical patent/DE60025958T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
DE60025958T 1999-12-02 2000-11-29 14,15-beta-methylen substituierte androgene Expired - Lifetime DE60025958T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99204080 1999-12-02
EP99204080 1999-12-02
PCT/EP2000/012009 WO2001040255A2 (en) 1999-12-02 2000-11-29 14,15-beta-methylene substituted androgens

Publications (2)

Publication Number Publication Date
DE60025958D1 true DE60025958D1 (de) 2006-04-20
DE60025958T2 DE60025958T2 (de) 2006-07-27

Family

ID=8240955

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60025958T Expired - Lifetime DE60025958T2 (de) 1999-12-02 2000-11-29 14,15-beta-methylen substituierte androgene

Country Status (27)

Country Link
US (1) US6706700B2 (de)
EP (1) EP1237904B1 (de)
JP (1) JP2003515543A (de)
CN (1) CN1166680C (de)
AR (1) AR026655A1 (de)
AT (1) ATE317396T1 (de)
AU (1) AU778017B2 (de)
CA (1) CA2390226A1 (de)
CO (1) CO5251441A1 (de)
CY (1) CY1106086T1 (de)
CZ (1) CZ301376B6 (de)
DE (1) DE60025958T2 (de)
DK (1) DK1237904T3 (de)
ES (1) ES2258037T3 (de)
HK (1) HK1047596B (de)
HU (1) HUP0203611A3 (de)
IL (1) IL149424A (de)
MX (1) MXPA02004939A (de)
NO (1) NO322422B1 (de)
NZ (1) NZ518753A (de)
PE (1) PE20011033A1 (de)
PL (1) PL202999B1 (de)
RU (1) RU2242479C2 (de)
SK (1) SK287095B6 (de)
TW (1) TWI275593B (de)
WO (1) WO2001040255A2 (de)
ZA (1) ZA200203536B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5209600A (en) * 1999-04-06 2000-10-23 Akzo Nobel N.V. Orally active androgens
RU2305105C2 (ru) * 2002-01-21 2007-08-27 Н.В.Органон СПОСОБ ПОЛУЧЕНИЯ 7α-МЕТИЛСТЕРОИДОВ, СОЕДИНЕНИЕ
US20080293683A1 (en) * 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy
EP2383279A1 (de) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Herstellungsverfahren für Esterol
PT2764008T (pt) * 2011-10-07 2016-11-10 Estetra Sprl Processo para a produção de estetrol
PT3106148T (pt) 2015-06-18 2018-05-10 Mithra Pharmaceuticals S A Resumo
CU24504B1 (es) 2015-06-18 2021-04-07 Estetra Sprl Unidad de dosificación orodispersable que contiene un componente estetrol y un proceso que incluye un paso de granulación para preparar el mismo
RS61812B1 (sr) 2015-06-18 2021-06-30 Estetra Sprl Oralno-disperzibilna tableta koja sadrži estetriol
HUE054551T2 (hu) 2015-06-18 2021-09-28 Estetra Sprl Ösztetrolt tartalmazó, szájban diszpergálódó tabletta
KR102712911B1 (ko) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
CN111621141B (zh) * 2020-06-12 2022-04-08 广西大学 一种缓释型二氧化氯-水性聚氨酯抗菌膜及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) * 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
IE60780B1 (en) 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE19537626A1 (de) * 1995-10-10 1997-04-17 Jenapharm Gmbh Steroide mit einer 14, 15-Methylengruppe
DE19827522A1 (de) * 1998-06-22 1999-12-23 Jenapharm Gmbh 14,15-Cyclopropanosteroide der 19-Nor-Androstanreihe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE60000826T2 (de) * 1999-03-08 2003-04-10 Akzo Nobel N.V., Arnheim/Arnhem 14.beta.,17-alpha-hydroxymethylandrostan derivate als androgene

Also Published As

Publication number Publication date
EP1237904A2 (de) 2002-09-11
AU778017B2 (en) 2004-11-11
SK287095B6 (sk) 2009-12-07
AU2838301A (en) 2001-06-12
PL355689A1 (en) 2004-05-17
HK1047596B (zh) 2006-04-21
HUP0203611A2 (hu) 2003-03-28
WO2001040255A3 (en) 2001-11-15
DK1237904T3 (da) 2006-06-06
SK7582002A3 (en) 2002-09-10
IL149424A (en) 2007-05-15
AR026655A1 (es) 2003-02-19
US20030100543A1 (en) 2003-05-29
NZ518753A (en) 2004-05-28
CO5251441A1 (es) 2003-02-28
NO20022564D0 (no) 2002-05-30
CN1402735A (zh) 2003-03-12
WO2001040255A2 (en) 2001-06-07
IL149424A0 (en) 2002-11-10
CA2390226A1 (en) 2001-06-07
DE60025958T2 (de) 2006-07-27
EP1237904B1 (de) 2006-02-08
NO20022564L (no) 2002-05-30
PL202999B1 (pl) 2009-08-31
ES2258037T3 (es) 2006-08-16
CN1166680C (zh) 2004-09-15
HK1047596A1 (en) 2003-02-28
JP2003515543A (ja) 2003-05-07
US6706700B2 (en) 2004-03-16
RU2242479C2 (ru) 2004-12-20
NO322422B1 (no) 2006-10-02
ZA200203536B (en) 2003-08-04
HUP0203611A3 (en) 2004-07-28
PE20011033A1 (es) 2001-10-11
CZ20021894A3 (cs) 2002-08-14
TWI275593B (en) 2007-03-11
MXPA02004939A (es) 2003-05-23
ATE317396T1 (de) 2006-02-15
CY1106086T1 (el) 2011-06-08
CZ301376B6 (cs) 2010-02-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: N.V. ORGANON, OSS, NL