DE60115418D1 - Mikroinfusionsvorrichtung zur verabreichung von medikamenten - Google Patents

Mikroinfusionsvorrichtung zur verabreichung von medikamenten

Info

Publication number
DE60115418D1
DE60115418D1 DE60115418T DE60115418T DE60115418D1 DE 60115418 D1 DE60115418 D1 DE 60115418D1 DE 60115418 T DE60115418 T DE 60115418T DE 60115418 T DE60115418 T DE 60115418T DE 60115418 D1 DE60115418 D1 DE 60115418D1
Authority
DE
Germany
Prior art keywords
medicaments
administration
microinfusion device
microinfusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115418T
Other languages
English (en)
Inventor
Joel Douglas
Robert Hugo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sterling Medivations Inc
Original Assignee
Sterling Medivations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/672,456 external-priority patent/US6629949B1/en
Application filed by Sterling Medivations Inc filed Critical Sterling Medivations Inc
Application granted granted Critical
Publication of DE60115418D1 publication Critical patent/DE60115418D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31518—Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DE60115418T 2000-05-08 2001-05-08 Mikroinfusionsvorrichtung zur verabreichung von medikamenten Expired - Lifetime DE60115418D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20281800P 2000-05-08 2000-05-08
US22363000P 2000-08-08 2000-08-08
US09/672,456 US6629949B1 (en) 2000-05-08 2000-09-29 Micro infusion drug delivery device
US09/845,256 US6659982B2 (en) 2000-05-08 2001-05-01 Micro infusion drug delivery device
PCT/US2001/014916 WO2001085233A2 (en) 2000-05-08 2001-05-08 Micro infusion drug delivery device

Publications (1)

Publication Number Publication Date
DE60115418D1 true DE60115418D1 (de) 2006-01-05

Family

ID=27498480

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60115418T Expired - Lifetime DE60115418D1 (de) 2000-05-08 2001-05-08 Mikroinfusionsvorrichtung zur verabreichung von medikamenten

Country Status (7)

Country Link
US (1) US6659982B2 (de)
EP (1) EP1280574B1 (de)
JP (1) JP2004516858A (de)
AU (1) AU2001261297A1 (de)
DE (1) DE60115418D1 (de)
IL (1) IL152318A0 (de)
WO (1) WO2001085233A2 (de)

Families Citing this family (170)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050277887A1 (en) * 2000-05-08 2005-12-15 Joel Douglas Micro infusion drug delivery device
WO2002045771A2 (en) * 2000-11-09 2002-06-13 Biovalve Technologies, Inc. Microneedle adapter
US7083597B2 (en) 2001-01-05 2006-08-01 Applied Diabetes Research, Inc. Pivoting joint infusion system with seal
US8343115B2 (en) * 2001-01-05 2013-01-01 Applied Diabetes Research, Inc. Low profile pivoting joint infusion assembly
US7776029B2 (en) * 2001-01-30 2010-08-17 The Alfred E. Mann Foundation For Scientific Research Microminiature infusion pump
EP1368080A4 (de) 2001-03-04 2007-08-15 Sterling Medivations Inc Infusionsansatzanordnung und fluidleitungstrennsystem
EP1395328B1 (de) * 2001-06-08 2006-08-16 Becton, Dickinson and Company Vorrichtung zur manipulation von nadeln oder polierarray
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US7004928B2 (en) * 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
ATE402724T1 (de) 2002-02-18 2008-08-15 Danfoss As Vorrichtung zur verabreichung eines medikaments in flüssiger form
BRPI0308307B8 (pt) * 2002-03-08 2021-06-22 Applied Diabetes Res Inc sistema de infusão para distribuição de um fluído de uma fonte remota para o corpo de um paciente
AU2003220143A1 (en) 2002-03-11 2003-09-29 Altea Therapeutics Corporation Transdermal integrated actuator device, methods of making and using same
US8116860B2 (en) 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US20030195609A1 (en) * 2002-04-10 2003-10-16 Scimed Life Systems, Inc. Hybrid stent
US7867193B2 (en) 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
US7338465B2 (en) 2002-07-02 2008-03-04 Patton Medical Devices, Lp Infusion device and method thereof
EP1556103A1 (de) 2002-10-07 2005-07-27 Novo Nordisk A/S Nadelvorrichtung mit einer vielzahl von nadeln
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
JP4565193B2 (ja) 2003-04-23 2010-10-20 バレリタス， インコーポレイテッド 長い持続時間の医薬投与のための液圧作動式ポンプ
KR20060014444A (ko) * 2003-06-19 2006-02-15 일라이 릴리 앤드 캄파니 멜라노코르틴 수용체 4 (ｍｃ4) 작용제 및 그의 용도
US20060293223A1 (en) * 2003-06-19 2006-12-28 Eli Lilly And Company Patent Division Uses of melanocortin-3 receptor (mc3r) agonist peptides
IL157984A (en) 2003-09-17 2015-02-26 Dali Medical Devices Ltd Automatic needle
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto injector
GB2406794B (en) * 2003-10-06 2008-03-05 Inverness Medical Ltd A lancing device using a piezoelectric actuator
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
US7867194B2 (en) 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
WO2005092410A1 (en) 2004-03-26 2005-10-06 Unomedical A/S Infusion set
US7872396B2 (en) 2004-06-14 2011-01-18 Massachusetts Institute Of Technology Electrochemical actuator
US8247946B2 (en) 2004-06-14 2012-08-21 Massachusetts Institute Of Technology Electrochemical actuator
US7999435B2 (en) 2004-06-14 2011-08-16 Massachusetts Institute Of Technology Electrochemical actuator
JP2008503059A (ja) 2004-06-14 2008-01-31 マサチューセッツ・インスティテュート・オブ・テクノロジー 電気化学的方法、デバイス、および構造体
US7994686B2 (en) 2004-06-14 2011-08-09 Massachusetts Institute Of Technology Electrochemical methods, devices, and structures
WO2006014425A1 (en) 2004-07-02 2006-02-09 Biovalve Technologies, Inc. Methods and devices for delivering glp-1 and uses thereof
US20060100584A1 (en) * 2004-08-10 2006-05-11 Orest Olejnik Needleless microprotrusion elastoplast system
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
EP1833452A1 (de) 2004-11-23 2007-09-19 Smith and Nephew, Inc. Kompositionsmischer
EP1824537A2 (de) 2004-12-10 2007-08-29 Unomedical A/S Kanüleneinführvorrichtung
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
US8603034B2 (en) 2005-07-12 2013-12-10 Applied Diabetes Research, Inc. One piece sealing reservoir for an insulin infusion pump
EP1752172A1 (de) * 2005-08-12 2007-02-14 F.Hoffmann-La Roche Ag Antriebsvorrichtung für eine Infusionspumpe
EP1940491B1 (de) 2005-08-22 2021-10-27 Medtronic Minimed, Inc. Fluidabgabevorrichtung
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
EP1762259B1 (de) 2005-09-12 2010-09-08 Unomedical A/S Einfürungssystem für ein Infusionsset mit einem ersten und zweiten Federeinheit
US9144645B2 (en) * 2005-09-21 2015-09-29 Applied Diabetes Research, Inc. One piece sealing reservoir for an insulin infusion pump
WO2007041244A2 (en) 2005-09-30 2007-04-12 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
RU2424003C2 (ru) 2005-11-03 2011-07-20 Паттон Медикал Дивайсиз, Лп Устройства, системы и способы доставки жидкостей
US20080200863A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
DK1962925T3 (da) 2005-12-23 2009-08-03 Unomedical As Indgivelsesanordning
US7892216B2 (en) 2006-02-07 2011-02-22 Icu Medical, Inc. Infusion set
KR20080104342A (ko) 2006-02-28 2008-12-02 우노메디컬 에이/에스 바늘 보호구를 구비하는 주입부와 주입부용 인서터
KR101361376B1 (ko) 2006-03-30 2014-02-10 발레리타스 인코포레이티드 복합-카트리지 유체 전달 장치
AU2007256561B2 (en) 2006-06-07 2012-07-19 Unomedical A/S Inserter for transcutaneous sensor
RU2438720C2 (ru) 2006-06-09 2012-01-10 Уномедикал А/С Установочная подкладка
EP2046419B1 (de) 2006-08-02 2011-04-13 Unomedical A/S Kanüle und abgabevorrichtung
WO2008020632A1 (fr) * 2006-08-18 2008-02-21 Toppan Printing Co., Ltd. Micro-aiguille et timbre à micro-aiguilles
EP1917990A1 (de) 2006-10-31 2008-05-07 Unomedical A/S Infusionsset
WO2008094672A2 (en) 2007-01-31 2008-08-07 Charles Stark Draper Laboratory, Inc. Membrane-based fluid control in microfluidic devices
US7931621B2 (en) * 2007-05-11 2011-04-26 Calibra Medical, Inc. Infusion assembly
DE202008017390U1 (de) 2007-06-20 2009-08-13 Unomedical A/S Katheter und Vorrichtung zum Herstellen eines solchen Katheters
CA2691341A1 (en) 2007-07-03 2009-01-08 Unomedical A/S Inserter having bistable equilibrium states
DK2173410T3 (da) 2007-07-10 2011-06-06 Unomedical As Inserter med to fjedre
WO2009010396A1 (en) 2007-07-18 2009-01-22 Unomedical A/S Insertion device with pivoting action
US7828771B2 (en) * 2007-07-26 2010-11-09 Entra Pharmaceuticals, Inc. Systems and methods for delivering drugs
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
WO2009079589A2 (en) 2007-12-17 2009-06-25 New World Pharmaceuticals, Llc Integrated intra-dermal delivery, diagnostic and communication system
AU2009214047A1 (en) 2008-02-13 2009-08-20 Unomedical A/S Sealing between a cannula part and a fluid path
AU2009216703A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
US20090259176A1 (en) * 2008-04-09 2009-10-15 Los Gatos Research, Inc. Transdermal patch system
GB0808389D0 (en) 2008-05-09 2008-06-18 Owen Mumford Ltd Electrically actuated injector
JP5816080B2 (ja) 2008-05-30 2015-11-17 インテュイティ メディカル インコーポレイテッド 体液採取装置及び採取部位インターフェイス
EP3984454A1 (de) 2008-06-06 2022-04-20 Intuity Medical, Inc. Blutzucker messgerät und methode zur verwendung
US9636051B2 (en) 2008-06-06 2017-05-02 Intuity Medical, Inc. Detection meter and mode of operation
US20130064834A1 (en) 2008-12-15 2013-03-14 Regeneron Pharmaceuticals, Inc. Methods for treating hypercholesterolemia using antibodies to pcsk9
JO3672B1 (ar) 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
AU2009331635A1 (en) 2008-12-22 2011-06-23 Unomedical A/S Medical device comprising adhesive pad
US9375529B2 (en) 2009-09-02 2016-06-28 Becton, Dickinson And Company Extended use medical device
US8197454B2 (en) * 2009-02-21 2012-06-12 Incumed, Llc Fluid cartridges and partially implantable medical devices for use with same
US9125981B2 (en) * 2009-02-21 2015-09-08 Incumed, Llc Fluid cartridges including a power source and partially implantable medical devices for use with same
US9370619B2 (en) * 2009-02-21 2016-06-21 Incumed, Llc Partially implantable medical devices and delivery/manifold tube for use with same
JP2013500099A (ja) 2009-07-30 2013-01-07 ウノメディカル・アー／エス 水平方向の可動部材を備えた挿入デバイス
US9533092B2 (en) 2009-08-07 2017-01-03 Unomedical A/S Base part for a medication delivery device
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
JP2011045565A (ja) * 2009-08-27 2011-03-10 Nanbu Plastics Co Ltd 薬液注入装置
EP3106871B1 (de) 2009-11-30 2021-10-27 Intuity Medical, Inc. Verfahren zum verifizieren der genauigkeit des betriebs einer analyt-überwachungsvorrichtung
JO3417B1 (ar) 2010-01-08 2019-10-20 Regeneron Pharma الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
BR112012024635A2 (pt) 2010-03-30 2017-08-08 Unomedical As dispositivo médico
US8337457B2 (en) 2010-05-05 2012-12-25 Springleaf Therapeutics, Inc. Systems and methods for delivering a therapeutic agent
US10330667B2 (en) 2010-06-25 2019-06-25 Intuity Medical, Inc. Analyte monitoring methods and systems
JOP20190250A1 (ar) 2010-07-14 2017-06-16 Regeneron Pharma صيغ مستقرة تحتوي على الأجسام المضادة لمضاد عامل نمو الأعصاب
US9216249B2 (en) 2010-09-24 2015-12-22 Perqflo, Llc Infusion pumps
US8915879B2 (en) 2010-09-24 2014-12-23 Perqflo, Llc Infusion pumps
US9320849B2 (en) 2010-09-24 2016-04-26 Perqflo, Llc Infusion pumps
US9498573B2 (en) 2010-09-24 2016-11-22 Perqflo, Llc Infusion pumps
EP2433663A1 (de) 2010-09-27 2012-03-28 Unomedical A/S Einführsystem
EP2436412A1 (de) 2010-10-04 2012-04-04 Unomedical A/S Sprinklerkanüle
CA2813587C (en) 2010-10-06 2019-01-15 Regeneron Pharmaceuticals, Inc. Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies
US9211378B2 (en) 2010-10-22 2015-12-15 Cequr Sa Methods and systems for dosing a medicament
US8905972B2 (en) 2010-11-20 2014-12-09 Perqflo, Llc Infusion pumps
EP2652324A2 (de) 2010-12-17 2013-10-23 Massachusetts Institute Of Technology Elektrochemische aktuatoren
JP6375113B2 (ja) 2011-01-28 2018-08-15 サノフィ・バイオテクノロジー 被験者の特定のグループを処置する方法において使用するためのｐｃｓｋ９に対するヒト抗体
WO2012106501A1 (en) 2011-02-02 2012-08-09 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
AR087305A1 (es) 2011-07-28 2014-03-12 Regeneron Pharma Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit
EP4339613A3 (de) 2011-08-03 2024-05-22 Intuity Medical, Inc. Vorrichtung zur entnahme von körperflüssigkeiten
MY170089A (en) 2011-09-16 2019-07-04 Regeneron Pharma Methods for reducing lipoproten(a) levels by administering an inhibitor of proprotein convertase subtilisin kexin-9 (pcsk9)
CN103957962B (zh) 2011-10-05 2017-07-07 犹诺医药有限公司 用于同时插入多个经皮部分的插入物
TWI589299B (zh) 2011-10-11 2017-07-01 再生元醫藥公司 用於治療類風濕性關節炎之組成物及其使用方法
US9943594B2 (en) 2011-10-11 2018-04-17 Sanofi Biotechnology Methods for the treatment of rheumatoid arthritis
EP2583715A1 (de) 2011-10-19 2013-04-24 Unomedical A/S Infusionsschlauchsystem und Herstellungsverfahren
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
CA2861062A1 (en) 2012-01-23 2013-08-01 Regeneron Pharmaceuticals, Inc. Stabilized formulations containing anti-ang2 antibodies
US20130315913A1 (en) 2012-03-26 2013-11-28 Sanofi Anti-light antibody therapy for inflammatory bowel disease
AR092325A1 (es) 2012-05-31 2015-04-15 Regeneron Pharma Formulaciones estabilizadas que contienen anticuerpos anti-dll4 y kit
SG11201500892UA (en) 2012-08-24 2015-03-30 Sanofi Sa Anti-poly-n-acetyl glucosamine (pnag) monoclonal antibody and uses thereof for the prevention or treatment of pnag expressing bacterial infection
EP3199552B1 (de) 2012-11-20 2019-12-25 Sanofi Anti-ceacam5-antikörper und verwendungen dafür
CN103083091B (zh) * 2013-01-28 2014-11-26 哈尔滨工业大学 一种基于压电驱动的倾斜角柔性针机器人辅助穿刺系统
HUE046702T2 (hu) 2013-03-20 2020-03-30 Genzyme Corp Eljárások üvegcsontbetegség kezelésére
US10111953B2 (en) 2013-05-30 2018-10-30 Regeneron Pharmaceuticals, Inc. Methods for reducing remnant cholesterol and other lipoprotein fractions by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)
WO2014205412A1 (en) 2013-06-21 2014-12-24 Intuity Medical, Inc. Analyte monitoring system with audible feedback
CN118105482A (zh) 2013-11-12 2024-05-31 赛诺菲生物技术公司 用于与pcsk9抑制剂一起使用的给药方案
PL3071230T3 (pl) 2013-11-22 2020-09-21 Sanofi Biotechnology Kompozycje do leczenia reumatoidalnego zapalenia stawów oraz sposoby ich stosowania
WO2016011256A1 (en) 2014-07-16 2016-01-21 Sanofi Biotechnology METHODS FOR TREATING PATIENTS WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (heFH)
EP3193934B1 (de) 2014-09-16 2021-07-21 Sanofi Biotechnology Zusammensetzungen zur verbesserung der gesundheitsbezogenen lebensqualität von patienten mit rheumatoider arthritis
US10159786B2 (en) 2014-09-30 2018-12-25 Perqflo, Llc Hybrid ambulatory infusion pumps
WO2016133789A2 (en) 2015-02-18 2016-08-25 Perqflo, Llc Ambulatory infusion pump and reservoir assemblies for use with same
USD776262S1 (en) 2015-07-30 2017-01-10 Becton, Dickinson And Company Medical injector
USD776265S1 (en) 2015-07-30 2017-01-10 Becton, Dickinson And Company Medical injector
USD767120S1 (en) 2015-07-30 2016-09-20 Becton, Dickinson And Company Medical injector
USD774640S1 (en) 2015-07-30 2016-12-20 Becton, Dickinson And Company Medical injector
USD776263S1 (en) 2015-07-30 2017-01-10 Becton, Dickinson And Company Medical injector
USD776264S1 (en) 2015-07-30 2017-01-10 Becton, Dickinson And Company Medical injector
USD794776S1 (en) 2015-07-30 2017-08-15 Becton, Dickinson And Company Medical injector
MA42657A (fr) 2015-08-18 2018-06-27 Regeneron Pharma Anticorps inhibiteurs anti-pcsk9 destinés au traitement des patients atteints d'hyperlipidémie subissant une aphérèse de lipoprotéines
WO2017066262A1 (en) 2015-10-12 2017-04-20 Swaminathan Jayaraman System and method for delivery of a therapeutic agent through a catheter
CN108473583A (zh) 2015-11-03 2018-08-31 赛诺菲生物技术公司 用于治疗葡萄膜炎和黄斑水肿的包含il6r抗体的组合物及其使用方法
CA3014280A1 (en) 2016-02-12 2017-08-17 Perqflo, Llc Ambulatory infusion pumps and assemblies for use with same
JP7193458B2 (ja) 2016-12-16 2022-12-20 ソレント・セラピューティクス・インコーポレイテッド 流体送達装置用のアプリケーション装置及びその使用方法
US11603407B2 (en) 2017-04-06 2023-03-14 Regeneron Pharmaceuticals, Inc. Stable antibody formulation
CA3062418A1 (en) 2017-05-06 2018-11-15 Regeneron Pharmaceuticals, Inc. Methods of treating eye disorders with aplnr antagonists and vegf inhibitors
CN107456625B (zh) * 2017-09-12 2018-08-14 美敦力公司 流体输注装置及其驱动系统
TW202026035A (zh) 2018-08-29 2020-07-16 美商再生元醫藥公司 用來治療患有類風濕性關節炎之個體的方法及組成物
CN111110841A (zh) 2018-10-31 2020-05-08 上海君实生物医药科技股份有限公司 含有抗pcsk9抗体的稳定制剂
US12036280B2 (en) 2018-11-21 2024-07-16 Regeneron Pharmaceuticals, Inc. High concentration protein formulation
MA54861A (fr) 2019-01-31 2021-12-08 Regeneron Pharma Anticorps anti-récepteur de l'il6 pour traiter l'arthrite idiopathique juvénile
KR20210124260A (ko) 2019-02-07 2021-10-14 사노피 폐암을 치료하기 위한 항-ceacam5 면역접합체의 용도
EP3693023A1 (de) 2019-02-11 2020-08-12 Sanofi Verwendung von anti-ceacam5-immunkonjugaten zur behandlung von lungenkrebs
US20200369760A1 (en) 2019-05-24 2020-11-26 Regeneron Pharmaceuticals, Inc. Stabilized formulations containing anti-angptl3 antibodies
MX2021014892A (es) 2019-06-04 2022-06-27 Sanofi Biotechnology Composiciones y metodos para el tratamiento del dolor en sujetos con artritis reumatoide.
KR102343362B1 (ko) * 2019-12-10 2021-12-29 주식회사 파우제 곡률 조절이 가능한 다중 주사바늘을 갖는 주사기구
TW202135860A (zh) 2019-12-10 2021-10-01 美商再生元醫藥公司 含有抗ｃｄ２０ｘ抗ｃｄ３雙特異性抗體之穩定調配物
MX2022008949A (es) 2020-01-24 2022-08-15 Regeneron Pharma Formulacion de anticuerpos estable.
WO2021240369A1 (en) 2020-05-26 2021-12-02 Sanofi Biotechnology Compositions comprising an antibody against interleukin-6 receptor for the treatment of rheumatoid arthritis and methods of using same
IL298087A (en) 2020-05-29 2023-01-01 Sanofi Biotechnology Compositions and methods for treating non-inflammatory pain in patients with rheumatoid arthritis
US20210393779A1 (en) 2020-06-18 2021-12-23 Regeneron Pharmaceuticals, Inc. Activin a antibody formulations and methods of use thereof
CN116710124A (zh) 2020-12-17 2023-09-05 瑞泽恩制药公司 包封蛋白质的微凝胶的制造
WO2024180192A1 (en) 2023-03-01 2024-09-06 Sanofi Use of anti-ceacam5 immunoconjugates for treating neuroendocrine cancers expressing ceacam5
WO2024213774A1 (en) 2023-04-14 2024-10-17 Kymab Limited Pharmaceutical formulations containing anti-ox40l antibodies

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584474A (de) 1968-02-20 1969-12-26
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
US3963380A (en) 1975-01-06 1976-06-15 Thomas Jr Lyell J Micro pump powered by piezoelectric disk benders
US3964484A (en) 1975-03-03 1976-06-22 Sorenson Research Co., Inc. Antiocoagulant metering device and method
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4235234A (en) 1978-11-30 1980-11-25 Martin John K Iii Subcutaneous injection system
US4276878A (en) 1979-08-20 1981-07-07 Karl Storz Injection syringe
JPS5695058A (en) * 1979-12-10 1981-08-01 Toyo Jozo Kk Microosyringe
US4313439A (en) 1980-03-24 1982-02-02 Biotek, Inc. Automated, spring-powered medicament infusion system
US4493704A (en) 1982-11-29 1985-01-15 Oximetrix, Inc. Portable fluid infusion apparatus
US4645495A (en) * 1985-06-26 1987-02-24 Vaillancourt Vincent L Vascular access implant needle patch
EP0245312B1 (de) 1985-11-08 1990-05-02 Disetronic Ag Injektionsgerät
DE3763287D1 (de) 1986-09-22 1990-07-26 Schering Ag Injektionseinrichtung.
US4741736A (en) 1986-12-10 1988-05-03 I-Flow Corporation Programmable infusion pump
DK177187A (da) 1987-04-07 1988-10-08 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glasampul
GB8713810D0 (en) 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
US4856340A (en) 1987-12-01 1989-08-15 Minimed Technologies Pressure diaphragm for a medication infusion system
US4813939A (en) * 1987-12-04 1989-03-21 Joel Marcus Winged infusion apparatus for patient implantable access ports
FR2625102B1 (fr) 1987-12-24 1994-06-10 Godefroy Alain Perfectionnement aux pousse-seringues universels
US4973318A (en) 1988-02-10 1990-11-27 D.C.P. Af 1988 A/S Disposable syringe
FR2628636B1 (fr) 1988-03-21 1991-03-29 Mms Sa Appareil pousse-seringue dote d'un dispositif perfectionne pour le maintien de la collerette terminale du piston d'une seringue sur le sabot-poussoir de cet appareil
US4969871A (en) 1989-02-15 1990-11-13 Alza Corporation Intravenous system for delivering a beneficial agent
US5716343A (en) * 1989-06-16 1998-02-10 Science Incorporated Fluid delivery apparatus
US5697901A (en) 1989-12-14 1997-12-16 Elof Eriksson Gene delivery by microneedle injection
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5206983A (en) 1991-06-24 1993-05-04 Wisconsin Alumni Research Foundation Method of manufacturing micromechanical devices
JP2855919B2 (ja) 1991-10-24 1999-02-10 日本電気株式会社 半導体装置およびその製造方法
US5279585A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Medication delivery pen having improved dose delivery features
DE4208483C2 (de) * 1992-03-17 2003-07-17 Braun Melsungen Ag Druckinfusionsapparat
DE4235506A1 (de) * 1992-10-21 1994-04-28 Bavaria Med Tech Katheter zur Injektion von Arzneimitteln
US5330431A (en) 1993-03-12 1994-07-19 Glenn Herskowitz Infusion pump
US5261882A (en) 1993-04-26 1993-11-16 Sealfon Andrew I Negator spring-powered syringe
US5957889A (en) 1993-09-27 1999-09-28 Novo Nordisk A/S Displacement system for controlled infusion of a liquid
DK109293D0 (da) 1993-09-27 1993-09-27 Novo Nordisk As Apparat
JP3590805B2 (ja) * 1993-11-10 2004-11-17 株式会社ニコン 採血装置
US5997501A (en) 1993-11-18 1999-12-07 Elan Corporation, Plc Intradermal drug delivery device
US5437999A (en) 1994-02-22 1995-08-01 Boehringer Mannheim Corporation Electrochemical sensor
DE4408108A1 (de) * 1994-03-10 1995-09-14 Bavaria Med Tech Katheter zur Injektion eines Fluid bzw. eines Arneimittelns
US5391250A (en) 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
US5457041A (en) * 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
US5464395A (en) * 1994-04-05 1995-11-07 Faxon; David P. Catheter for delivering therapeutic and/or diagnostic agents to the tissue surrounding a bodily passageway
US5914507A (en) 1994-05-11 1999-06-22 Regents Of The University Of Minnesota PZT microdevice
CA2149836C (en) 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration
US5637095A (en) 1995-01-13 1997-06-10 Minimed Inc. Medication infusion pump with flexible drive plunger
US5644177A (en) 1995-02-23 1997-07-01 Wisconsin Alumni Research Foundation Micromechanical magnetically actuated devices
US5640995A (en) 1995-03-14 1997-06-24 Baxter International Inc. Electrofluidic standard module and custom circuit board assembly
HU219757B (hu) 1995-06-02 2001-07-30 Novo Nordisk A/S Fecskendő gyógyszer adagolt injekciózására cserélhető patronból
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
GB9606829D0 (en) 1996-03-30 1996-06-05 Jeffrey Peter Supplying materials etc
EP0934093B1 (de) * 1996-09-17 2003-01-15 Deka Products Limited Partnership System zur medikamentenabgabe durch transport
EP1595562A3 (de) 1997-01-10 2006-08-02 Japan Servo Co. Ltd. Liquidinfusionvorrichtung
US6796970B1 (en) 1997-06-17 2004-09-28 Novo Nordisk A/S Dose setting device
US6050988A (en) * 1997-12-11 2000-04-18 Alza Corporation Device for enhancing transdermal agent flux
AU757192B2 (en) 1997-12-11 2003-02-06 Alza Corporation Device for enhancing transdermal agent flux
US6016693A (en) 1998-02-09 2000-01-25 The Regents Of The University Of California Microfabrication of cantilevers using sacrificial templates
US5957895A (en) 1998-02-20 1999-09-28 Becton Dickinson And Company Low-profile automatic injection device with self-emptying reservoir
US6022316A (en) 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
US6106751A (en) 1998-03-18 2000-08-22 The Regents Of The University Of California Method for fabricating needles via conformal deposition in two-piece molds
JP2002517300A (ja) 1998-06-10 2002-06-18 ジョージア テック リサーチ コーポレイション 微小針デバイスおよび製造方法ならびにそれらの使用
JP2002526273A (ja) 1998-09-18 2002-08-20 ザ ユニヴァーシティ オブ ユタ リサーチ ファウンデーション 表面マイクロマシニングしたマイクロニードル
EP1140275A1 (de) 1998-12-18 2001-10-10 Minimed Inc. Einführvorrichtungen mit mikrostechelementen zum gebrauch in medizinischen vorrichtungen und methoden zu ihrem gebrauch
US6302870B1 (en) * 1999-04-29 2001-10-16 Precision Vascular Systems, Inc. Apparatus for injecting fluids into the walls of blood vessels, body cavities, and the like
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array

Also Published As

Publication number Publication date
JP2004516858A (ja) 2004-06-10
EP1280574A2 (de) 2003-02-05
US6659982B2 (en) 2003-12-09
WO2001085233A3 (en) 2002-06-06
US20010053887A1 (en) 2001-12-20
WO2001085233A2 (en) 2001-11-15
EP1280574B1 (de) 2005-11-30
IL152318A0 (en) 2003-05-29
AU2001261297A1 (en) 2001-11-20

Similar Documents

Publication Publication Date Title
DE60115418D1 (de) Mikroinfusionsvorrichtung zur verabreichung von medikamenten
DE69935681D1 (de) Vorrichtungen zur Medikamentverabreichung
DE69934773D1 (de) Vorrichtung zur Verabreichung von Medikamenten
DE60126321D1 (de) Gelsystem zur ocularen verabreichung von arzneimitteln
NO20030627L (no) Hydrogel-drevet medikament doseringsform
NO20022970L (no) Hydrogel-drevet medikamentdoseringsform
DE60220661D1 (de) Transdermales pflaster zur verabreichung von fentanyl
ATE401859T1 (de) Vorrichtungen zur verabreichung von arzneistoffen mit antiprogestinischen eigenschaften
DK1473003T3 (da) Lægemiddeladministrationsanordning
DE60027492D1 (de) Gerät zur Gesundheitsverwaltung
DE60115698D1 (de) Medikamentenspender
DE60333294D1 (de) Kontrollierte verabreichung von arzneien
ITTO20010008A0 (it) Formulazione farmaceutica
ATE289500T1 (de) Ophtalmologische medikamentenzuführvorrichtung
NO20041315L (no) Medikamentavleveringssystem
DE60014279D1 (de) Stiftförmige Medikamentenspritze
ATE307571T1 (de) Pharmazeutische formulierung enthaltend bicalutamid
ATE265852T1 (de) Geschmackskaschierte flüssige arzneizubereitungen
DE60132600D1 (de) Medikamente zur chemotherapeutischen behandlung von erkrankungen
NO20030139L (no) Farmasöytiske preparater inneholdende DDS forbindelser
NO20020531D0 (no) Beta-carbolin medikament produkter
DE50209245D1 (de) Neuroprotektives medikament
NO20024194L (no) Nytt selvemulgerende legemiddelavleveringssystem
FI20000780A (fi) Peroraalinen lääkemuoto lääkeaineen hallituksi vapauttamiseksi
DE69832974D1 (de) Gerät zur intrakardialen verabreichung von medikamenten

Legal Events

Date Code Title Description
8332 No legal effect for de