TBL1XR1
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timeline
title Publication timing
2012-03-06 : Lohr : DLBCL
2012-08-27 : Rossi : MZL
2013-08-15 : Morin : DLBCL
2016-03-01 : Mareschal : DLBCL
2017-10-10 : Reddy : DLBCL
2018-04-12 : Schmitz : DLBCL
2018-05-01 : Chapuy : DLBCL
2018-10-01 : Arthur : DLBCL
| Entity | Tier | Description |
|---|---|---|
 |
1 | high-confidence MZL gene[@rossiCodingGenomeSplenic2012c] |
 |
1 | high-confidence PMBL/cHL/GZL gene |
 |
1 | high-confidence DLBCL gene [@lohrDiscoveryPrioritizationSomatic2012a; @morinMutationalStructuralAnalysis2013] |
 |
1 | high-confidence FL gene |
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 8.60 |
| DLBCL | Schmitz cohort | 12.77 |
| DLBCL | Reddy cohort | 5.71 |
| DLBCL | Chapuy cohort | 8.12 |
| FL | GAMBL genomes | 3.93 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | Yes | 17.892 | 29.577 |
| DLBCL | No | Yes | 24.811 | 24.179 |
| FL | No | No | 12.400 | 18.940 |
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr3 | 176752066 | A>C | H390Q |
| chr3 | 176752053 | A>T | Y395N |
| chr3 | 176752053 | A>C | Y395D |
| chr3 | 176752052 | T>C | Y395C |
| chr3 | 176750839 | A>G | Y446H |
| chr3 | 176750838 | T>G | Y446S |
| chr3 | 176750838 | T>C | Y446C |
| chr3 | 176750836 | T>G | S447R |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
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