FI861573A0 - Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi - Google Patents

Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi

Info

Publication number
FI861573A0
FI861573A0 FI861573A FI861573A FI861573A0 FI 861573 A0 FI861573 A0 FI 861573A0 FI 861573 A FI861573 A FI 861573A FI 861573 A FI861573 A FI 861573A FI 861573 A0 FI861573 A0 FI 861573A0
Authority
FI
Finland
Prior art keywords
anticonvulsant
fluorinated
benzyl
preparation
triazole compounds
Prior art date
Application number
FI861573A
Other languages
English (en)
Swedish (sv)
Other versions
FI861573A (fi
FI93544C (fi
FI93544B (fi
Inventor
Rene Meier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI861573A0 publication Critical patent/FI861573A0/fi
Publication of FI861573A publication Critical patent/FI861573A/fi
Application granted granted Critical
Publication of FI93544B publication Critical patent/FI93544B/fi
Publication of FI93544C publication Critical patent/FI93544C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/46Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI861573A 1985-04-18 1986-04-14 Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi FI93544C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18
CH166385 1985-04-18

Publications (4)

Publication Number Publication Date
FI861573A0 true FI861573A0 (fi) 1986-04-14
FI861573A FI861573A (fi) 1986-10-19
FI93544B FI93544B (fi) 1995-01-13
FI93544C FI93544C (fi) 1995-04-25

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861573A FI93544C (fi) 1985-04-18 1986-04-14 Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi

Country Status (22)

Country Link
EP (1) EP0199262B1 (fi)
JP (1) JPS61243068A (fi)
KR (1) KR900008810B1 (fi)
AU (1) AU599024B2 (fi)
CA (1) CA1272201A (fi)
CY (1) CY1751A (fi)
DD (1) DD245874A5 (fi)
DE (1) DE3677626D1 (fi)
DK (1) DK169720B1 (fi)
ES (2) ES8800176A1 (fi)
FI (1) FI93544C (fi)
GR (1) GR861004B (fi)
HK (1) HK1494A (fi)
HU (1) HU203327B (fi)
IE (1) IE58472B1 (fi)
IL (1) IL78510A (fi)
MX (1) MX9203628A (fi)
NO (1) NO164295C (fi)
NZ (1) NZ215871A (fi)
PH (1) PH22568A (fi)
PT (1) PT82400B (fi)
ZA (1) ZA862873B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
AU2633897A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
CZ294775B6 (cs) * 1996-07-11 2005-03-16 Novartis Ag Způsob přípravy 1-substituovaných 4-kyan-1,2,3-triazolů
TW403740B (en) 1997-06-10 2000-09-01 Novartis Ag Novel crystal modifications of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
IT1393368B1 (it) * 2009-03-23 2012-04-20 Dipharma Francis Srl Metodo per la preparazione di rufinamide
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
EP2727914A1 (en) * 2010-04-30 2014-05-07 Laboratorios Lesvi, S.L. Polymorph of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-carboxamide
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
US20150368211A1 (en) * 2013-01-31 2015-12-24 The Johns Hopkins University Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
CN108697662A (zh) 2015-12-11 2018-10-23 奥胡斯大学 用于治疗肌强直的卢非酰胺
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (fi) * 1982-12-23 1984-06-24 Ciba Geigy Ag Foerfarande foer framstaellning av nya aralkyltriazolfoereningar.

Also Published As

Publication number Publication date
KR900008810B1 (ko) 1990-11-30
JPH0564949B2 (fi) 1993-09-16
AU599024B2 (en) 1990-07-12
DK169720B1 (da) 1995-01-23
DE3677626D1 (de) 1991-04-04
HK1494A (en) 1994-01-14
EP0199262A2 (de) 1986-10-29
NO164295B (no) 1990-06-11
ES8802501A1 (es) 1988-07-01
ZA862873B (en) 1986-12-30
EP0199262B1 (de) 1991-02-27
DK175686A (da) 1986-10-19
CA1272201A (en) 1990-07-31
FI861573A (fi) 1986-10-19
PT82400B (pt) 1988-08-17
ES557641A0 (es) 1988-07-01
JPS61243068A (ja) 1986-10-29
ES554024A0 (es) 1987-10-16
NO861486L (no) 1986-10-20
IL78510A0 (en) 1986-08-31
IL78510A (en) 1992-05-25
AU5631986A (en) 1986-10-23
CY1751A (en) 1994-06-03
FI93544C (fi) 1995-04-25
EP0199262A3 (en) 1987-08-26
FI93544B (fi) 1995-01-13
NO164295C (no) 1990-09-19
ES8800176A1 (es) 1987-10-16
PT82400A (en) 1986-05-01
NZ215871A (en) 1989-01-27
HU203327B (en) 1991-07-29
MX9203628A (es) 1992-09-01
DK175686D0 (da) 1986-04-17
KR860008152A (ko) 1986-11-12
GR861004B (en) 1986-08-12
PH22568A (en) 1988-10-17
IE58472B1 (en) 1993-09-22
IE861015L (en) 1986-10-18
DD245874A5 (de) 1987-05-20
HUT40792A (en) 1987-02-27

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BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired