FI861573A - Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi - Google Patents
Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi Download PDFInfo
- Publication number
- FI861573A FI861573A FI861573A FI861573A FI861573A FI 861573 A FI861573 A FI 861573A FI 861573 A FI861573 A FI 861573A FI 861573 A FI861573 A FI 861573A FI 861573 A FI861573 A FI 861573A
- Authority
- FI
- Finland
- Prior art keywords
- anticonvulsant
- fluorinated
- benzyl
- preparation
- triazole compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH166385 | 1985-04-18 | ||
CH166385 | 1985-04-18 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI861573A0 FI861573A0 (fi) | 1986-04-14 |
FI861573A true FI861573A (fi) | 1986-10-19 |
FI93544B FI93544B (fi) | 1995-01-13 |
FI93544C FI93544C (fi) | 1995-04-25 |
Family
ID=4215715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI861573A FI93544C (fi) | 1985-04-18 | 1986-04-14 | Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0199262B1 (fi) |
JP (1) | JPS61243068A (fi) |
KR (1) | KR900008810B1 (fi) |
AU (1) | AU599024B2 (fi) |
CA (1) | CA1272201A (fi) |
CY (1) | CY1751A (fi) |
DD (1) | DD245874A5 (fi) |
DE (1) | DE3677626D1 (fi) |
DK (1) | DK169720B1 (fi) |
ES (2) | ES8800176A1 (fi) |
FI (1) | FI93544C (fi) |
GR (1) | GR861004B (fi) |
HK (1) | HK1494A (fi) |
HU (1) | HU203327B (fi) |
IE (1) | IE58472B1 (fi) |
IL (1) | IL78510A (fi) |
MX (1) | MX9203628A (fi) |
NO (1) | NO164295C (fi) |
NZ (1) | NZ215871A (fi) |
PH (1) | PH22568A (fi) |
PT (1) | PT82400B (fi) |
ZA (1) | ZA862873B (fi) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0151528B1 (en) * | 1984-02-02 | 1990-07-04 | Merck & Co. Inc. | 5-(amino or substituted amino)-1,2,3-triazoles |
AU2633897A (en) * | 1996-04-19 | 1997-11-12 | Novo Nordisk A/S | Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles |
US6156907A (en) * | 1996-07-11 | 2000-12-05 | Novartis Ag | Process for preparing 1-substituted 4-cyano-1,2,3-triazoles |
TW526195B (en) | 1997-06-10 | 2003-04-01 | Novartis Ag | Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use |
TW513301B (en) * | 1999-03-01 | 2002-12-11 | Novartis Ag | Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders |
WO2004106329A2 (en) * | 2003-06-03 | 2004-12-09 | Dr. Reddy's Laboratories Ltd. | Novel antiinfective compounds and their pharmaceutical compositions |
IT1393368B1 (it) * | 2009-03-23 | 2012-04-20 | Dipharma Francis Srl | Metodo per la preparazione di rufinamide |
IT1395736B1 (it) | 2009-08-04 | 2012-10-19 | Dipharma Francis Srl | Forme cristalline di rufinamide |
ES2498267T3 (es) * | 2010-04-30 | 2014-09-24 | Laboratorios Lesvi, S.L. | Procedimiento mejorado para la preparación de un intermedio de rufinamida |
ITMI20110718A1 (it) | 2011-04-29 | 2012-10-30 | Dipharma Francis Srl | Procedimento per la purificazione di rufinamide |
WO2014120994A1 (en) * | 2013-01-31 | 2014-08-07 | The Johns Hopkins University | Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels |
US9771335B2 (en) * | 2015-07-31 | 2017-09-26 | The Johns Hopkins University | Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels |
EP3386491B1 (en) | 2015-12-11 | 2021-12-08 | Aarhus Universitet | Rufinamide for use in the treatment of myotonia |
WO2021099481A1 (en) | 2019-11-20 | 2021-05-27 | Medichem, S.A. | Solid composition containing rufinamide |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1511195A (en) * | 1976-10-18 | 1978-05-17 | Ici America Inc | Triazole derivatives |
FI834666A (fi) * | 1982-12-23 | 1984-06-24 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya aralkyltriazolfoereningar. |
-
1986
- 1986-04-14 FI FI861573A patent/FI93544C/fi not_active IP Right Cessation
- 1986-04-14 PH PH33651A patent/PH22568A/en unknown
- 1986-04-15 EP EP86105188A patent/EP0199262B1/de not_active Expired - Lifetime
- 1986-04-15 IL IL78510A patent/IL78510A/xx not_active IP Right Cessation
- 1986-04-15 DE DE8686105188T patent/DE3677626D1/de not_active Expired - Lifetime
- 1986-04-16 GR GR861004A patent/GR861004B/el unknown
- 1986-04-16 ES ES554024A patent/ES8800176A1/es not_active Expired
- 1986-04-16 CA CA000506774A patent/CA1272201A/en not_active Expired - Lifetime
- 1986-04-16 PT PT82400A patent/PT82400B/pt unknown
- 1986-04-16 NO NO861486A patent/NO164295C/no unknown
- 1986-04-16 DD DD86289243A patent/DD245874A5/de not_active IP Right Cessation
- 1986-04-17 AU AU56319/86A patent/AU599024B2/en not_active Expired
- 1986-04-17 ZA ZA862873A patent/ZA862873B/xx unknown
- 1986-04-17 IE IE101586A patent/IE58472B1/en not_active IP Right Cessation
- 1986-04-17 KR KR1019860002954A patent/KR900008810B1/ko not_active IP Right Cessation
- 1986-04-17 DK DK175686A patent/DK169720B1/da not_active IP Right Cessation
- 1986-04-17 HU HU861615A patent/HU203327B/hu unknown
- 1986-04-17 NZ NZ215871A patent/NZ215871A/xx unknown
- 1986-04-18 JP JP61088384A patent/JPS61243068A/ja active Granted
-
1987
- 1987-07-31 ES ES557641A patent/ES8802501A1/es not_active Expired
-
1992
- 1992-06-26 MX MX9203628A patent/MX9203628A/es unknown
-
1994
- 1994-01-06 HK HK14/94A patent/HK1494A/xx not_active IP Right Cessation
- 1994-06-03 CY CY175194A patent/CY1751A/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
PC | Transfer of assignment of patent |
Owner name: NOVARTIS AG |
|
FG | Patent granted |
Owner name: NOVARTIS AG |
|
MA | Patent expired |