EA201300246A1 - Ингибиторы тирозинкиназы брутона - Google Patents

Ингибиторы тирозинкиназы брутона

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Publication number
EA201300246A1
EA201300246A1 EA201300246A EA201300246A EA201300246A1 EA 201300246 A1 EA201300246 A1 EA 201300246A1 EA 201300246 A EA201300246 A EA 201300246A EA 201300246 A EA201300246 A EA 201300246A EA 201300246 A1 EA201300246 A1 EA 201300246A1
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EA
Eurasian Patent Office
Prior art keywords
conditions
compounds
bluton
diseases
inhibitors
Prior art date
Application number
EA201300246A
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English (en)
Other versions
EA024255B1 (ru
Inventor
Ли Хонигберг
Эрик Вернер
Женгьинг Пан
Original Assignee
Фармасайкликс, Инк.
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39225888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201300246(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Фармасайкликс, Инк. filed Critical Фармасайкликс, Инк.
Publication of EA201300246A1 publication Critical patent/EA201300246A1/ru
Publication of EA024255B1 publication Critical patent/EA024255B1/ru

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Abstract

В заявке описаны соединения, образующие ковалентные связи с тирозинкиназой Брутона (Btk). Также описаны необратимые ингибиторы Btk. Описаны способы получения таких соединений. Также описаны фармацевтические композиции, содержащие такие соединения. Описаны способы применения ингибиторов Btk отдельно или в комбинации с другими терапевтическими агентами для лечения аутоиммунных заболеваний или состояний, гетероиммунных заболеваний или состояний, рака, включая лимфому, и воспалительных заболеваний или состояний.
EA201300246A 2006-09-22 2006-12-28 Синтез ингибиторов тирозинкиназы брутона EA024255B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82672006P 2006-09-22 2006-09-22
US82859006P 2006-10-06 2006-10-06

Publications (2)

Publication Number Publication Date
EA201300246A1 true EA201300246A1 (ru) 2014-01-30
EA024255B1 EA024255B1 (ru) 2016-08-31

Family

ID=39225888

Family Applications (3)

Application Number Title Priority Date Filing Date
EA201000599A EA020001B1 (ru) 2006-09-22 2006-12-28 Ингибиторы тирозинкиназы брутона
EA200900351A EA018573B1 (ru) 2006-09-22 2006-12-28 Ингибиторы тирозинкиназы брутона
EA201300246A EA024255B1 (ru) 2006-09-22 2006-12-28 Синтез ингибиторов тирозинкиназы брутона

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EA201000599A EA020001B1 (ru) 2006-09-22 2006-12-28 Ингибиторы тирозинкиназы брутона
EA200900351A EA018573B1 (ru) 2006-09-22 2006-12-28 Ингибиторы тирозинкиназы брутона

Country Status (28)

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US (49) US7514444B2 (ru)
EP (11) EP2443929A1 (ru)
JP (4) JP4934197B2 (ru)
KR (4) KR20100051863A (ru)
CN (4) CN101805341B (ru)
AT (1) ATE531263T1 (ru)
AU (2) AU2006348662B8 (ru)
BR (2) BRPI0622054B8 (ru)
CA (3) CA2663116C (ru)
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