CY1116295T1 - Αναστολεις της κινασης τυροσινης toy bruton - Google Patents

Αναστολεις της κινασης τυροσινης toy bruton

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Publication number
CY1116295T1
CY1116295T1 CY20151100453T CY151100453T CY1116295T1 CY 1116295 T1 CY1116295 T1 CY 1116295T1 CY 20151100453 T CY20151100453 T CY 20151100453T CY 151100453 T CY151100453 T CY 151100453T CY 1116295 T1 CY1116295 T1 CY 1116295T1
Authority
CY
Cyprus
Prior art keywords
tyrosine kinase
disclosed
bruton
toy
suspensions
Prior art date
Application number
CY20151100453T
Other languages
English (en)
Inventor
Lee Honigberg
Erik Verner
Zhengying Pan
Tarak Mody
Original Assignee
Pharmacyclics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39225888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1116295(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacyclics, Inc. filed Critical Pharmacyclics, Inc.
Publication of CY1116295T1 publication Critical patent/CY1116295T1/el

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

Γνωστοποιούνται στο παρόν ενώσεις οι οποίες σχηματίζουν ομοιοπολικούς δεσμούς με κινάση τυροσίνης του Bruton (Btk). Επίσης περιγράφονται στο παρόν μη-αντιστρεπτοί αναστολείς της Btk. Μέθοδοι για την παρασκευή των ενώσεων γνωστοποιούνται. Επίσης γνωστοποιούνται φαρμακευτικές συνθέσεις οι οποίες περιλαμβάνουν τις ενώσεις. Μέθοδοι χρήσης των Btk αναστολέων γνωστοποιούνται, μόνων ή σε συνδυασμό με άλλους θεραπευτικούς παράγοντες, για την αντιμετώπιση διαταραχών του πολλαπλασιασμού των Β-κυττάρων.
CY20151100453T 2006-09-22 2015-05-20 Αναστολεις της κινασης τυροσινης toy bruton CY1116295T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82672006P 2006-09-22 2006-09-22
US82859006P 2006-10-06 2006-10-06
EP12166301.7A EP2526933B1 (en) 2006-09-22 2006-12-28 Inhibitors of Bruton's tyrosine kinase

Publications (1)

Publication Number Publication Date
CY1116295T1 true CY1116295T1 (el) 2017-02-08

Family

ID=39225888

Family Applications (11)

Application Number Title Priority Date Filing Date
CY20121100100T CY1112513T1 (el) 2006-09-22 2012-01-27 Αναστολεις της κινασης τυροσινης του bruton
CY2015016C CY2015016I2 (el) 2006-09-22 2015-04-03 Αναστολεις της κινασης τυροσινης του bruton
CY20151100453T CY1116295T1 (el) 2006-09-22 2015-05-20 Αναστολεις της κινασης τυροσινης toy bruton
CY20161100196T CY1117587T1 (el) 2006-09-22 2016-03-07 Αναστολεις κινασης τυροσινης bruton
CY20161100734T CY1117840T1 (el) 2006-09-22 2016-07-26 Αναστολεις κινασης τυροσινης bruton
CY20161100765T CY1117897T1 (el) 2006-09-22 2016-08-03 Αναστολεις κινασης τυροσινης bruton
CY2016041C CY2016041I1 (el) 2006-09-22 2016-11-15 Αναστολεις κινασης τυροσινης bruton
CY20161101348T CY1119209T1 (el) 2006-09-22 2016-12-27 Αναστολεις κινασης τυροσινης bruton
CY20171100248T CY1118666T1 (el) 2006-09-22 2017-02-22 Αναστολεις κινασης τυροσινης bruton
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