AU472312B2 - Novel pyrimidino derivatives - Google Patents

Novel pyrimidino derivatives

Info

Publication number
AU472312B2
AU472312B2 AU60197/73A AU6019773A AU472312B2 AU 472312 B2 AU472312 B2 AU 472312B2 AU 60197/73 A AU60197/73 A AU 60197/73A AU 6019773 A AU6019773 A AU 6019773A AU 472312 B2 AU472312 B2 AU 472312B2
Authority
AU
Australia
Prior art keywords
pyrimidino
derivatives
novel
pyrimidino derivatives
novel pyrimidino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU60197/73A
Other languages
English (en)
Other versions
AU6019773A (en
Inventor
Jacob Vander Burg Willem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of AU6019773A publication Critical patent/AU6019773A/en
Application granted granted Critical
Publication of AU472312B2 publication Critical patent/AU472312B2/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU60197/73A 1972-09-23 1973-09-11 Novel pyrimidino derivatives Expired AU472312B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NLNL72.12915 1972-09-23
NLAANVRAGE7212915,A NL176458C (nl) 1972-09-23 1972-09-23 Werkwijze ter bereiding van een farmaceutisch preparaat en werkwijze voor de bereiding van daartoe geschikte actieve stoffen.

Publications (2)

Publication Number Publication Date
AU6019773A AU6019773A (en) 1975-03-13
AU472312B2 true AU472312B2 (en) 1976-05-20

Family

ID=19816997

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60197/73A Expired AU472312B2 (en) 1972-09-23 1973-09-11 Novel pyrimidino derivatives

Country Status (18)

Country Link
US (1) US3892695A (es)
JP (1) JPS5912678B2 (es)
AR (1) AR203090A1 (es)
AU (1) AU472312B2 (es)
BE (1) BE805178A (es)
CA (1) CA1019733A (es)
CH (1) CH592094A5 (es)
DE (1) DE2347727C2 (es)
DK (1) DK140668B (es)
ES (1) ES418996A1 (es)
FI (1) FI54311C (es)
FR (1) FR2199996B1 (es)
GB (1) GB1445765A (es)
HU (1) HU167206B (es)
IE (1) IE38221B1 (es)
NL (1) NL176458C (es)
SE (1) SE407686B (es)
ZA (1) ZA737131B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217452A (en) * 1974-02-09 1980-08-12 Akzona Incorporated Synthesis for the preparation of tetracyclic compounds
NL179906C (nl) * 1974-02-09 1986-12-01 Akzo Nv Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.
NL7414038A (nl) * 1974-10-28 1976-05-03 Akzo Nv Nieuwe tetracyclische pyrrolidino derivaten.
GB1472382A (en) * 1975-01-16 1977-05-04 Wyeth John & Brother Ltd Dibenzopyrimidoazepines
NL7610942A (nl) * 1976-10-02 1978-04-04 Akzo Nv Werkwijze voor het bereiden van 1,4-diazepine derivaten.
NL7809726A (nl) * 1978-09-26 1980-03-28 Akzo Nv Nieuwe tetracyclische verbindingen.
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
CH678623A5 (en) * 1989-05-17 1991-10-15 Sochinaz Societe Chimique De V Prepn. of di:benzo pyrazino azepine(s)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154511B (nl) * 1967-07-07 1977-09-15 Organon Nv Werkwijze ter bereiding van piperazinederivaten, werkwijze ter bereiding van een farmaceutisch preparaat, dat een dergelijke verbinding bevat en vormstukken bereid volgens deze werkwijze.
US3470181A (en) * 1967-10-23 1969-09-30 American Home Prod Fused 2-pyrimidinepropionic acid compounds,related compounds,and the process for their preparation

Also Published As

Publication number Publication date
BE805178A (fr) 1974-03-21
CH592094A5 (es) 1977-10-14
IE38221B1 (en) 1978-01-18
NL7212915A (es) 1974-03-26
DE2347727A1 (de) 1974-04-04
DE2347727C2 (de) 1986-12-11
ZA737131B (en) 1974-08-28
NL176458B (nl) 1984-11-16
FR2199996A1 (es) 1974-04-19
FI54311C (fi) 1978-11-10
FR2199996B1 (es) 1977-09-09
JPS4985098A (es) 1974-08-15
AR203090A1 (es) 1975-08-14
HU167206B (es) 1975-09-27
NL176458C (nl) 1985-04-16
SE407686B (sv) 1979-04-09
JPS5912678B2 (ja) 1984-03-24
GB1445765A (en) 1976-08-11
DK140668C (es) 1980-03-24
US3892695A (en) 1975-07-01
DK140668B (da) 1979-10-22
ES418996A1 (es) 1976-07-01
AU6019773A (en) 1975-03-13
FI54311B (fi) 1978-07-31
IE38221L (en) 1974-03-23
CA1019733A (en) 1977-10-25

Similar Documents

Publication Publication Date Title
AU467361B2 (en) Q-aryl-4-substituted piperidinoalkanol derivatives
AU496759B2 (en) New pregnan-21-oic derivatives
AU472312B2 (en) Novel pyrimidino derivatives
CA1019738A (en) Isothiocyanopyridine derivatives
AU470719B2 (en) Oxazinoindole-and thiazinoinindole derivatives
CA976967A (en) Diphenylalkyllactamimide derivatives
CA1020946A (en) 1-phenoxy-3-phenoxyethylamino-2-propanol derivatives
AU470763B2 (en) Pyrano-and thiopyranoindole derivatives
CA1006514A (en) Beta-aminoketone derivatives
CA1018161A (en) Indan-1-carboxamide derivatives
CA978526A (en) Pyrano- and thiopyranoindole derivatives
CA981684A (en) Cyclopenteno-quinolone derivatives
AU5556173A (en) New nitrofuryl-amidine derivatives
CA896560A (en) 6-phenyl-dihydropyridazine-3-one derivatives
CA916153A (en) Dihydropyrimidopyridazine derivatives
AU482792B2 (en) Indan-1-carboxamide derivatives
AU477427B2 (en) 2-fluoro-substituted thiazanthene derivatives
CA893701A (en) Triazolobenzodiazepinone derivatives
CA891502A (en) Benhydrylquinuclidinol derivatives
CA898253A (en) Styryl-naphthalene derivatives
CA899353A (en) 1-hydroxyproline derivatives
CA899886A (en) Oxotremarine derivatives
CA901015A (en) Benzophenonimine derivatives
CA904852A (en) Tetrahydrocyclopropadibenzazepine derivatives
CA904885A (en) 1-amino-3-phenoxy-2-propanol derivatives