ATE308365T1 - Zusammensetzungen zur oralen verabreichung von taxanen und deren verwendung - Google Patents

Zusammensetzungen zur oralen verabreichung von taxanen und deren verwendung

Info

Publication number
ATE308365T1
ATE308365T1 AT98918361T AT98918361T ATE308365T1 AT E308365 T1 ATE308365 T1 AT E308365T1 AT 98918361 T AT98918361 T AT 98918361T AT 98918361 T AT98918361 T AT 98918361T AT E308365 T1 ATE308365 T1 AT E308365T1
Authority
AT
Austria
Prior art keywords
taxans
compositions
oral administration
oral
administration
Prior art date
Application number
AT98918361T
Other languages
English (en)
Inventor
Samuel Broder
Kenneth L Duchin
Sami Selim
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Application granted granted Critical
Publication of ATE308365T1 publication Critical patent/ATE308365T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98918361T 1997-05-27 1998-04-22 Zusammensetzungen zur oralen verabreichung von taxanen und deren verwendung ATE308365T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86351397A 1997-05-27 1997-05-27
PCT/US1998/007776 WO1998053811A1 (en) 1997-05-27 1998-04-22 Method and compositions for administering taxanes orally to human patients

Publications (1)

Publication Number Publication Date
ATE308365T1 true ATE308365T1 (de) 2005-11-15

Family

ID=25341241

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98918361T ATE308365T1 (de) 1997-05-27 1998-04-22 Zusammensetzungen zur oralen verabreichung von taxanen und deren verwendung

Country Status (23)

Country Link
EP (1) EP0994706B1 (de)
JP (1) JP2002500667A (de)
KR (1) KR100615783B1 (de)
CN (2) CN1261275A (de)
AR (1) AR012731A1 (de)
AT (1) ATE308365T1 (de)
AU (1) AU7130098A (de)
BR (1) BR9809694A (de)
CA (1) CA2290446C (de)
CZ (1) CZ9904244A3 (de)
DE (1) DE69832173T2 (de)
DK (1) DK0994706T3 (de)
ES (1) ES2247690T3 (de)
HK (1) HK1026637A1 (de)
HU (1) HUP0003546A3 (de)
IL (2) IL132992A0 (de)
NO (1) NO995812L (de)
PL (1) PL337064A1 (de)
RU (1) RU2205005C2 (de)
SK (1) SK157599A3 (de)
UA (1) UA74767C2 (de)
WO (1) WO1998053811A1 (de)
ZA (1) ZA984268B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964946B1 (en) * 1995-10-26 2005-11-15 Baker Norton Pharmaceuticals, Inc. Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
ATE219363T1 (de) * 1997-06-20 2002-07-15 Baker Norton Pharma Lösliche prodrugs von paclitaxel
GB9718903D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
AU4955200A (en) 1999-05-17 2000-12-05 Cancer Research Ventures Limited A method of improving bioavailability of orally administered drugs, a method of screening for enhancers of such bioavailability and novel pharmaceutical compositions for oral delivery of drugs
JP2003512443A (ja) * 1999-10-27 2003-04-02 ベーカー ノートン ファーマシューティカルズ インコーポレイテッド タキサンをヒト患者に経口投与するための方法及び組成物
KR20020013174A (ko) * 2000-08-11 2002-02-20 민경윤 경구 흡수율이 낮은 약물의 흡수율을 증가시키기 위한경구용 조성물
JP2004520398A (ja) * 2001-01-18 2004-07-08 ファルマシア・アンド・アップジョン・カンパニー 経口生物学的利用能が改善されたパクリタキセルの化学療法マイクロエマルジョン組成物
US7115565B2 (en) 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
EP1623706A3 (de) * 2001-02-28 2006-02-22 Bristol-Myers Squibb Company Metronomische Dosierung von Taxane zur Hemmung des Krebswuchses
UY27185A1 (es) * 2001-02-28 2002-09-30 Bristol Myers Squibb Co Dosificación metronómica de taxanos
US7063977B2 (en) 2001-08-21 2006-06-20 Bristol-Myers Squibb Company Enzymatic resolution of t-butyl taxane derivatives
GB0523659D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
CA2763893A1 (en) * 2009-06-02 2010-12-09 Nikan Pharmaceuticals, Llc Antagonism of human formyl peptide receptor for treatment of disease
EP4059497A1 (de) * 2021-03-17 2022-09-21 Dompé farmaceutici S.p.a. C5ar1 inhibitoren zur behandlung von hypersensitivitätsreaktionen auf taxane
JP2024512472A (ja) * 2021-03-17 2024-03-19 ドムペ・ファルマチェウティチ・ソチエタ・ペル・アツィオーニ タキサンに対する過敏性反応を治療するためのc5ar1阻害薬

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411947A (en) * 1989-06-28 1995-05-02 Vestar, Inc. Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
JPH06504772A (ja) * 1990-12-18 1994-06-02 ザ ウエルカム ファウンデーション リミテッド 抗癌剤の薬効を増強し抗多剤耐性を有する薬剤
AU652996B2 (en) * 1991-01-11 1994-09-15 Laboratoires Glaxo S.A. Acridine derivatives
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
CZ293076B6 (cs) * 1994-07-26 2004-02-18 Indena S. P. A. Polosyntetické taxany, způsob jejich výroby, farmaceutické prostředky s jejich obsahem a meziprodukty pro jejich výrobu
TW354293B (en) * 1995-06-06 1999-03-11 Bristol Myers Squibb Co Prodrugs of paclitaxel derivatives
US5916566A (en) * 1995-06-07 1999-06-29 Avmax, Inc. Use of benzoin gum to inhibit P-glycoprotein-mediated resistance of pharmaceutical compounds
US6245805B1 (en) * 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
CA2221444A1 (en) * 1996-01-31 1997-08-07 Steven B. Hansel A method of making pharmaceutically active taxanes orally bioavailable
JP2000512997A (ja) * 1996-06-17 2000-10-03 イーライ・リリー・アンド・カンパニー 薬物耐性および多薬物耐性調節物質
GB9718903D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
KR100661879B1 (ko) * 1998-04-01 2006-12-27 스키에파마 캐나다 인코포레이티드 항암 조성물

Also Published As

Publication number Publication date
CA2290446A1 (en) 1998-12-03
DE69832173T2 (de) 2006-08-03
HK1026637A1 (en) 2000-12-22
WO1998053811A1 (en) 1998-12-03
CZ9904244A3 (cs) 2001-10-17
AR012731A1 (es) 2000-11-08
RU2205005C2 (ru) 2003-05-27
EP0994706B1 (de) 2005-11-02
KR100615783B1 (ko) 2006-08-25
DE69832173D1 (de) 2005-12-08
EP0994706A1 (de) 2000-04-26
CN1550231A (zh) 2004-12-01
KR20010013025A (ko) 2001-02-26
IL132992A (en) 2006-08-20
NO995812D0 (no) 1999-11-26
CN1261275A (zh) 2000-07-26
BR9809694A (pt) 2000-10-03
IL132992A0 (en) 2001-03-19
DK0994706T3 (da) 2006-03-06
UA74767C2 (en) 2006-02-15
ES2247690T3 (es) 2006-03-01
SK157599A3 (en) 2002-10-08
ZA984268B (en) 1999-06-23
PL337064A1 (en) 2000-07-31
AU7130098A (en) 1998-12-30
HUP0003546A3 (en) 2002-12-28
NO995812L (no) 2000-01-25
CA2290446C (en) 2008-01-29
HUP0003546A2 (hu) 2002-11-28
EP0994706A4 (de) 2001-05-16
JP2002500667A (ja) 2002-01-08

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