SE9902765D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE9902765D0 SE9902765D0 SE9902765A SE9902765A SE9902765D0 SE 9902765 D0 SE9902765 D0 SE 9902765D0 SE 9902765 A SE9902765 A SE 9902765A SE 9902765 A SE9902765 A SE 9902765A SE 9902765 D0 SE9902765 D0 SE 9902765D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- therapy
- processes
- preparation
- treatment
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 102000009410 Chemokine receptor Human genes 0.000 abstract 1
- 108050000299 Chemokine receptor Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9902765A SE9902765D0 (sv) | 1999-07-21 | 1999-07-21 | Novel compounds |
KR1020027000797A KR20020027498A (ko) | 1999-07-21 | 2000-07-18 | 신규 디페닐-피페리딘 유도체 |
PCT/GB2000/002756 WO2001005782A1 (en) | 1999-07-21 | 2000-07-18 | Novel diphenyl-piperidine derivate |
JP2001511441A JP2003505383A (ja) | 1999-07-21 | 2000-07-18 | 新規ジフェニル−ピペリジン誘導体 |
AU60016/00A AU771344B2 (en) | 1999-07-21 | 2000-07-18 | Novel diphenyl-piperidine derivate |
EP00946134A EP1202984B1 (en) | 1999-07-21 | 2000-07-18 | diphenyl-piperidine derivate |
NZ516606A NZ516606A (en) | 1999-07-21 | 2000-07-18 | Novel diphenyl-piperidine derivate |
CA002378084A CA2378084A1 (en) | 1999-07-21 | 2000-07-18 | Novel diphenyl-piperidine derivate |
BR0012610-1A BR0012610A (pt) | 1999-07-21 | 2000-07-18 | Novo derivado de difenilpiperidina |
IL14714900A IL147149A0 (en) | 1999-07-21 | 2000-07-18 | Novel diphenyl-piperidine derivate |
MXPA02000671A MXPA02000671A (es) | 1999-07-21 | 2000-07-18 | Novedoso derivado de difenil-piperidina. |
CNB008106703A CN1152873C (zh) | 1999-07-21 | 2000-07-18 | 新的二苯基哌啶衍生物 |
AT00946134T ATE233754T1 (de) | 1999-07-21 | 2000-07-18 | Diphenyl-piperidin derivate |
US09/623,744 US6566376B1 (en) | 1999-07-21 | 2000-07-18 | Diphenyl-piperidine derivative |
DE60001586T DE60001586T2 (de) | 1999-07-21 | 2000-07-18 | Diphenyl-piperidin derivate |
ZA200110540A ZA200110540B (en) | 1999-07-21 | 2001-12-21 | Novel diphenyl-piperidine derivate. |
NO20020282A NO20020282L (no) | 1999-07-21 | 2002-01-18 | Nytt difenyl-piperidinderivat |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9902765A SE9902765D0 (sv) | 1999-07-21 | 1999-07-21 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9902765D0 true SE9902765D0 (sv) | 1999-07-21 |
Family
ID=20416552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9902765A SE9902765D0 (sv) | 1999-07-21 | 1999-07-21 | Novel compounds |
Country Status (17)
Country | Link |
---|---|
US (1) | US6566376B1 (pt) |
EP (1) | EP1202984B1 (pt) |
JP (1) | JP2003505383A (pt) |
KR (1) | KR20020027498A (pt) |
CN (1) | CN1152873C (pt) |
AT (1) | ATE233754T1 (pt) |
AU (1) | AU771344B2 (pt) |
BR (1) | BR0012610A (pt) |
CA (1) | CA2378084A1 (pt) |
DE (1) | DE60001586T2 (pt) |
IL (1) | IL147149A0 (pt) |
MX (1) | MXPA02000671A (pt) |
NO (1) | NO20020282L (pt) |
NZ (1) | NZ516606A (pt) |
SE (1) | SE9902765D0 (pt) |
WO (1) | WO2001005782A1 (pt) |
ZA (1) | ZA200110540B (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200303304A (en) * | 2002-02-18 | 2003-09-01 | Astrazeneca Ab | Chemical compounds |
SE0400208D0 (sv) | 2004-02-02 | 2004-02-02 | Astrazeneca Ab | Chemical compounds |
US20100286191A1 (en) * | 2005-12-12 | 2010-11-11 | Samuel Rachel G | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators |
US10344095B2 (en) * | 2006-02-16 | 2019-07-09 | University Of Kentucky Research Foundation | CCR3 inhibition for ocular angiogenesis and macular degeneration |
TW200812582A (en) * | 2006-04-06 | 2008-03-16 | Astrazeneca Ab | Medicaments |
CA2691662A1 (en) * | 2007-07-02 | 2009-01-08 | F. Hoffmann-La Roche Ag | Imidazole derivatives as ccr2 receptor antagonists |
WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
WO2010138591A1 (en) | 2009-05-26 | 2010-12-02 | University Of Kentucky Research Foundation | Ccr3 and its ligands are therapeutic and diagnostic targets for neovascular age-related macular degeneration |
WO2014153214A1 (en) | 2013-03-14 | 2014-09-25 | Epizyme, Inc. | Arginine methyl transferase inhibtors and uses thereof |
EP2970133B1 (en) | 2013-03-14 | 2018-10-24 | Epizyme, Inc. | Pyrazole derivatives as prmt1 inhibitors and uses thereof |
US8952026B2 (en) | 2013-03-14 | 2015-02-10 | Epizyme, Inc. | PRMT1 inhibitors and uses thereof |
US9765035B2 (en) | 2013-03-14 | 2017-09-19 | Epizyme, Inc. | Arginine methyltransferase inhibitors and uses thereof |
US9776972B2 (en) | 2013-03-14 | 2017-10-03 | Epizyme Inc. | Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof |
WO2014153208A1 (en) | 2013-03-14 | 2014-09-25 | Epizyme, Inc. | Arginine methyltransferase inhibitors and uses thereof |
US9023883B2 (en) | 2013-03-14 | 2015-05-05 | Epizyme, Inc. | PRMT1 inhibitors and uses thereof |
US9365527B2 (en) | 2013-03-14 | 2016-06-14 | Epizyme, Inc. | Arginine methyltransferase inhibitors and uses thereof |
US9120757B2 (en) | 2013-03-14 | 2015-09-01 | Epizyme, Inc. | Arginine methyltransferase inhibitors and uses thereof |
PL2970132T3 (pl) | 2013-03-14 | 2021-04-06 | Epizyme, Inc. | Inhibitory metylotransferazy argininy i ich zastosowania |
PT3022202T (pt) | 2013-07-18 | 2019-09-03 | Novartis Ag | Inibidores da autotaxina compreendendo um núcleo beteroaromático anel-benzilo-amida-ciclo |
CN108299411B (zh) | 2017-01-13 | 2021-02-05 | 中国人民解放军军事医学科学院毒物药物研究所 | 4,4-二苯基哌啶类化合物或其可药用盐、药物组合物及用途 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2139084C3 (de) | 1971-08-04 | 1979-03-01 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Verfahren zur Herstellung von 4,4-Diphenyl-piperidinen |
IL90858A (en) | 1988-07-07 | 1994-08-26 | Rhone Poulenc Sante | History (Aza) Naftalensultam, their preparation and preparations containing them |
AU652747B2 (en) | 1990-04-10 | 1994-09-08 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pyridines as medicaments |
DE4140542A1 (de) | 1991-12-09 | 1993-06-17 | Bayer Ag | Piperdylmethyl substituierte chormanderivate |
IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
US6339087B1 (en) | 1997-08-18 | 2002-01-15 | Syntex (U.S.A.) Llc | Cyclic amine derivatives-CCR-3 receptor antagonists |
DE19756235A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide |
HN1999000149A (es) * | 1998-09-09 | 2000-01-12 | Pfizer Prod Inc | Derivados de 4,4-biarilpiperidina |
US6046331A (en) | 1998-12-17 | 2000-04-04 | Synaptic Pharmaceutical Corporation | Imidazolones and their use in treating benign prostatic hyperplasia and other disorders |
-
1999
- 1999-07-21 SE SE9902765A patent/SE9902765D0/xx unknown
-
2000
- 2000-07-18 CA CA002378084A patent/CA2378084A1/en not_active Abandoned
- 2000-07-18 DE DE60001586T patent/DE60001586T2/de not_active Expired - Fee Related
- 2000-07-18 AT AT00946134T patent/ATE233754T1/de not_active IP Right Cessation
- 2000-07-18 IL IL14714900A patent/IL147149A0/xx unknown
- 2000-07-18 KR KR1020027000797A patent/KR20020027498A/ko not_active Application Discontinuation
- 2000-07-18 BR BR0012610-1A patent/BR0012610A/pt not_active IP Right Cessation
- 2000-07-18 JP JP2001511441A patent/JP2003505383A/ja not_active Withdrawn
- 2000-07-18 EP EP00946134A patent/EP1202984B1/en not_active Expired - Lifetime
- 2000-07-18 NZ NZ516606A patent/NZ516606A/en unknown
- 2000-07-18 US US09/623,744 patent/US6566376B1/en not_active Expired - Fee Related
- 2000-07-18 WO PCT/GB2000/002756 patent/WO2001005782A1/en active IP Right Grant
- 2000-07-18 MX MXPA02000671A patent/MXPA02000671A/es active IP Right Grant
- 2000-07-18 AU AU60016/00A patent/AU771344B2/en not_active Ceased
- 2000-07-18 CN CNB008106703A patent/CN1152873C/zh not_active Expired - Fee Related
-
2001
- 2001-12-21 ZA ZA200110540A patent/ZA200110540B/xx unknown
-
2002
- 2002-01-18 NO NO20020282A patent/NO20020282L/no unknown
Also Published As
Publication number | Publication date |
---|---|
WO2001005782A1 (en) | 2001-01-25 |
NO20020282D0 (no) | 2002-01-18 |
IL147149A0 (en) | 2002-08-14 |
CA2378084A1 (en) | 2001-01-25 |
ZA200110540B (en) | 2003-03-24 |
JP2003505383A (ja) | 2003-02-12 |
ATE233754T1 (de) | 2003-03-15 |
MXPA02000671A (es) | 2002-07-02 |
DE60001586D1 (de) | 2003-04-10 |
DE60001586T2 (de) | 2004-02-12 |
NO20020282L (no) | 2002-03-21 |
EP1202984B1 (en) | 2003-03-05 |
AU6001600A (en) | 2001-02-05 |
NZ516606A (en) | 2003-09-26 |
CN1152873C (zh) | 2004-06-09 |
US6566376B1 (en) | 2003-05-20 |
AU771344B2 (en) | 2004-03-18 |
CN1361775A (zh) | 2002-07-31 |
KR20020027498A (ko) | 2002-04-13 |
BR0012610A (pt) | 2002-04-09 |
EP1202984A1 (en) | 2002-05-08 |
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