PT70699A - Procede de preparation de pyrido-indoles applicables en therapeutique - Google Patents

Procede de preparation de pyrido-indoles applicables en therapeutique

Info

Publication number
PT70699A
PT70699A PT70699A PT7069980A PT70699A PT 70699 A PT70699 A PT 70699A PT 70699 A PT70699 A PT 70699A PT 7069980 A PT7069980 A PT 7069980A PT 70699 A PT70699 A PT 70699A
Authority
PT
Portugal
Prior art keywords
alk
compounds
cooalk
indoles
pyrido
Prior art date
Application number
PT70699A
Other languages
English (en)
French (fr)
Inventor
Gabor Koletar
Jonathan Frost
Regis Dupont
Patrick Lardenois
Claude Morel
Henry Najer
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of PT70699A publication Critical patent/PT70699A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT70699A 1979-04-26 1980-01-15 Procede de preparation de pyrido-indoles applicables en therapeutique PT70699A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7910654A FR2455044A1 (fr) 1979-04-26 1979-04-26 Pyrido-indoles et leur application en therapeutique

Publications (1)

Publication Number Publication Date
PT70699A true PT70699A (fr) 1980-02-01

Family

ID=9224797

Family Applications (1)

Application Number Title Priority Date Filing Date
PT70699A PT70699A (fr) 1979-04-26 1980-01-15 Procede de preparation de pyrido-indoles applicables en therapeutique

Country Status (15)

Country Link
US (2) US4272539A (pt)
EP (1) EP0021857B1 (pt)
JP (1) JPS55145687A (pt)
AT (1) ATE2078T1 (pt)
AU (1) AU528231B2 (pt)
CA (1) CA1146942A (pt)
DE (1) DE3061373D1 (pt)
DK (1) DK16880A (pt)
ES (2) ES8102124A1 (pt)
FR (1) FR2455044A1 (pt)
GR (1) GR74393B (pt)
IL (1) IL59131A (pt)
NO (1) NO794272L (pt)
PT (1) PT70699A (pt)
ZA (1) ZA80243B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3229215A1 (de) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung
DE3309596A1 (de) * 1982-08-05 1984-04-05 Basf Ag, 6700 Ludwigshafen 2-substituierte 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung als arzneimittel
US4719211A (en) * 1984-05-01 1988-01-12 American Home Products Corporation 2,3,4,9-tetrahydro-2-heteroarylalkyl-1H-pyrido(3,4-B)indoles having antihypertensive properties
JP2527319B2 (ja) * 1986-12-25 1996-08-21 川研ファインケミカル株式会社 7―ブロモ―β―カルボリン誘導体の製造方法
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
FR2663935A1 (fr) * 1990-06-27 1992-01-03 Adir Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DE4104257A1 (de) * 1991-02-13 1992-08-20 Boehringer Ingelheim Kg Verwendung von anellierten tetrahydropyridinessigsaeurederivaten fuer die behandlung neurologischer erkrankungen
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
US5466688A (en) * 1994-10-20 1995-11-14 American Home Products Corporation Pyrido[3,4-B]indole derivatives as serotonergic agents
FR2796644B1 (fr) * 1999-07-23 2001-09-07 Adir Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB841225A (en) * 1957-09-12 1960-07-13 Roche Products Ltd Novel quinolizine derivatives and process for the manufacture of same
GB1055203A (en) * 1964-09-16 1967-01-18 Ici Ltd -ß-carboline derivatives, a process for their manufacture, and compositions containing them
US4091102A (en) * 1975-08-22 1978-05-23 Endo Laboratories, Inc. Anti-depressant trans-hexahydropyrido[3,4-b]indoles
ATE165T1 (de) * 1978-07-28 1981-09-15 Synthelabo Fluoren- und fluoranthenderivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
US4220774A (en) * 1978-10-26 1980-09-02 Omnium Chimique Vincadifformine synthesis process

Also Published As

Publication number Publication date
US4336256A (en) 1982-06-22
ES487714A0 (es) 1980-12-16
DK16880A (da) 1980-10-27
AU5463180A (en) 1980-10-30
ATE2078T1 (de) 1983-01-15
IL59131A0 (en) 1980-05-30
AU528231B2 (en) 1983-04-21
ES8102124A1 (es) 1980-12-16
ZA80243B (en) 1980-12-31
FR2455044B1 (pt) 1982-05-21
IL59131A (en) 1983-10-31
GR74393B (pt) 1984-06-28
CA1146942A (en) 1983-05-24
FR2455044A1 (fr) 1980-11-21
DE3061373D1 (en) 1983-01-27
JPS55145687A (en) 1980-11-13
NO794272L (no) 1980-10-28
EP0021857B1 (fr) 1982-12-22
ES8105733A1 (es) 1981-06-16
EP0021857A1 (fr) 1981-01-07
ES494263A0 (es) 1981-06-16
US4272539A (en) 1981-06-09

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