PL2604691T3 - Środki i sposoby przeciwdziałania, opóźniania i/lub zapobiegania włączaniu niekorzystnego metabolizmu energetycznego w chorobach serca - Google Patents

Środki i sposoby przeciwdziałania, opóźniania i/lub zapobiegania włączaniu niekorzystnego metabolizmu energetycznego w chorobach serca

Info

Publication number
PL2604691T3
PL2604691T3 PL13158674T PL13158674T PL2604691T3 PL 2604691 T3 PL2604691 T3 PL 2604691T3 PL 13158674 T PL13158674 T PL 13158674T PL 13158674 T PL13158674 T PL 13158674T PL 2604691 T3 PL2604691 T3 PL 2604691T3
Authority
PL
Poland
Prior art keywords
counteracting
delaying
methods
heart disease
energy metabolism
Prior art date
Application number
PL13158674T
Other languages
English (en)
Inventor
De Leon Johannes Windt
Azzouzi Hamid El
Original Assignee
Univ Maastricht
Acad Ziekenhuis Maastricht
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maastricht, Acad Ziekenhuis Maastricht filed Critical Univ Maastricht
Publication of PL2604691T3 publication Critical patent/PL2604691T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/113Antisense targeting other non-coding nucleic acids, e.g. antagomirs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • C12N2310/141MicroRNAs, miRNAs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL13158674T 2009-08-06 2009-08-06 Środki i sposoby przeciwdziałania, opóźniania i/lub zapobiegania włączaniu niekorzystnego metabolizmu energetycznego w chorobach serca PL2604691T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09788267A EP2462228A1 (en) 2009-08-06 2009-08-06 Means and methods for counteracting, delaying and/or preventing adverse energy metabolism switches in heart disease
PCT/NL2009/050484 WO2011016714A1 (en) 2009-08-06 2009-08-06 Means and methods for counteracting, delaying and/or preventing adverse energy metabolism switches in heart disease
EP13158674.5A EP2604691B1 (en) 2009-08-06 2009-08-06 Means and methods for counteracting, delaying and/or preventing adverse energy metabolism switches in heart disease

Publications (1)

Publication Number Publication Date
PL2604691T3 true PL2604691T3 (pl) 2015-05-29

Family

ID=41503694

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13158674T PL2604691T3 (pl) 2009-08-06 2009-08-06 Środki i sposoby przeciwdziałania, opóźniania i/lub zapobiegania włączaniu niekorzystnego metabolizmu energetycznego w chorobach serca

Country Status (6)

Country Link
US (2) US8815822B2 (pl)
EP (2) EP2604691B1 (pl)
CA (1) CA2770130C (pl)
ES (1) ES2531964T3 (pl)
PL (1) PL2604691T3 (pl)
WO (1) WO2011016714A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2531964T3 (es) 2009-08-06 2015-03-23 Universiteit Maastricht Medios y métodos para contrarrestar, demorar y/o prevenir cambios adversos del metabolismo energético en enfermedades del corazón
WO2012115987A2 (en) * 2011-02-21 2012-08-30 The Trustees Of Columbia University In The City Of New York Methods for Treating and Preventing Cardiac Dysfunction in Septic Shock
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
CN108524534A (zh) * 2018-05-15 2018-09-14 南京市儿童医院 miR-214拮抗剂在制备治疗高血压产品中的应用
CN110885824B (zh) * 2019-12-11 2021-12-07 武汉大学 miRNA-199核酸抑制物及其在翼状胬肉中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7683036B2 (en) * 2003-07-31 2010-03-23 Regulus Therapeutics Inc. Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
US7772389B2 (en) * 2004-02-13 2010-08-10 Rockefeller University Anti-microRNA oligonucleotide molecules
US20100286044A1 (en) * 2005-12-29 2010-11-11 Exiqon A/S Detection of tissue origin of cancer
EP2094869B1 (de) * 2006-10-09 2012-07-25 Julius-Maximilians-Universität Würzburg Microrna (mirna) zur diagnose und therapie von herzerkrankungen
ES2689508T3 (es) * 2007-10-04 2018-11-14 Roche Innovation Center Copenhagen A/S Micromir
US20110152352A1 (en) * 2008-06-10 2011-06-23 Tufts University Smad proteins control drosha-mediated mirna maturation
US20110086348A1 (en) * 2009-02-19 2011-04-14 The Cleveland Clinic Foundation Method for assessing heart disease
US20100292278A1 (en) * 2009-05-15 2010-11-18 Yochai Birnbaum Methods of treating vascular disease and injury
US9072765B2 (en) * 2009-05-20 2015-07-07 Board Of Regents, The University Of Texas System Identification of micro-RNAs involved in post-myocardial infarction remodeling and heart failure
ES2531964T3 (es) 2009-08-06 2015-03-23 Universiteit Maastricht Medios y métodos para contrarrestar, demorar y/o prevenir cambios adversos del metabolismo energético en enfermedades del corazón

Also Published As

Publication number Publication date
CA2770130C (en) 2018-02-27
US9611480B2 (en) 2017-04-04
CA2770130A1 (en) 2011-02-10
US8815822B2 (en) 2014-08-26
US20140357699A1 (en) 2014-12-04
ES2531964T3 (es) 2015-03-23
EP2462228A1 (en) 2012-06-13
EP2604691B1 (en) 2014-12-03
US20120141442A1 (en) 2012-06-07
WO2011016714A1 (en) 2011-02-10
EP2604691A1 (en) 2013-06-19

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