NO143218C - Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet - Google Patents

Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet

Info

Publication number
NO143218C
NO143218C NO743538A NO743538A NO143218C NO 143218 C NO143218 C NO 143218C NO 743538 A NO743538 A NO 743538A NO 743538 A NO743538 A NO 743538A NO 143218 C NO143218 C NO 143218C
Authority
NO
Norway
Prior art keywords
nonapeptidamides
activity
preparation
analogy procedure
analogy
Prior art date
Application number
NO743538A
Other languages
English (en)
Norwegian (no)
Other versions
NO143218B (no
NO743538L (da
Inventor
Masahiko Fujino
Tsunehiko Fukuda
Susumu Shinagawa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26365357&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO143218(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP10995173A external-priority patent/JPS5314072B2/ja
Priority claimed from JP2744274A external-priority patent/JPS5726506B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO743538L publication Critical patent/NO743538L/no
Publication of NO143218B publication Critical patent/NO143218B/no
Publication of NO143218C publication Critical patent/NO143218C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO743538A 1973-09-29 1974-09-30 Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet NO143218C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10995173A JPS5314072B2 (da) 1973-09-29 1973-09-29
JP2744274A JPS5726506B2 (da) 1974-03-08 1974-03-08

Publications (3)

Publication Number Publication Date
NO743538L NO743538L (da) 1975-04-28
NO143218B NO143218B (no) 1980-09-22
NO143218C true NO143218C (no) 1981-01-02

Family

ID=26365357

Family Applications (2)

Application Number Title Priority Date Filing Date
NO743538A NO143218C (no) 1973-09-29 1974-09-30 Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet
NO1994010C NO1994010I1 (no) 1973-09-29 1994-08-18 Leuprorelin

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1994010C NO1994010I1 (no) 1973-09-29 1994-08-18 Leuprorelin

Country Status (17)

Country Link
US (1) US4008209A (da)
AT (1) AT347054B (da)
BE (1) BE820451A (da)
CA (1) CA1027114A (da)
CH (1) CH603559A5 (da)
CS (1) CS180644B2 (da)
DE (1) DE2446005C2 (da)
DK (1) DK148305C (da)
ES (1) ES430495A1 (da)
FI (1) FI61028C (da)
FR (1) FR2245375B1 (da)
GB (1) GB1434694A (da)
HK (1) HK15579A (da)
HU (1) HU173783B (da)
NL (3) NL179289C (da)
NO (2) NO143218C (da)
SE (1) SE420717B (da)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2735515A1 (de) * 1977-08-06 1979-02-22 Hoechst Ag Verwendung von lh-rh-peptiden als antikonzeptive
FR2450109B1 (fr) * 1977-11-08 1986-03-28 Roussel Uclaf Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes
US4215038A (en) * 1978-10-16 1980-07-29 The Salk Institute For Biological Studies Peptides which inhibit gonadal function
US4359312A (en) * 1978-08-15 1982-11-16 Zumtobel Kg Reciprocating pump for the pulsation-free delivery of a liquid
US4256737A (en) * 1979-06-11 1981-03-17 Syntex (U.S.A.) Inc. Long acting depot injectable formulations for LH-RH analogues
DE3020941A1 (de) * 1980-06-03 1981-12-17 Hoechst Ag, 6000 Frankfurt Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung
ZA815447B (en) * 1980-08-29 1982-08-25 Salk Inst For Biological Studi Peptides affecting gonadal function
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
CS230614B1 (en) * 1982-08-06 1984-08-13 Martin Cs Flegel Analogues of realising factor for luteining and folliculstimulated hormon
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
IT1178775B (it) * 1983-12-23 1987-09-16 Konzponti Valto Es Hitelbank R Derivati della gonadoliberina e procedimento per la loro preparazione
HU189394B (en) * 1983-12-23 1986-06-30 Koezponti Valto- Es Hitelbank Rt Innovacios Alap,Hu Method for producing spermatozoa suitable for fertilization from mature fishes
DE3411224A1 (de) * 1984-03-27 1985-10-10 Hoechst Ag, 6230 Frankfurt Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
HU193093B (en) * 1985-04-16 1987-08-28 Innofinance Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation
HU193607B (en) * 1985-07-18 1987-11-30 Innofinance Altalanos Innovaci Process for production of sexual products applyable for natural or artificial insemination for mammates
US4762717A (en) * 1986-03-21 1988-08-09 The General Hospital Corporation Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
JP2653255B2 (ja) 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
CA2050425A1 (en) 1990-09-03 1992-03-04 Yoshiaki Uda Pharmaceutical composition and its mucous use
NO302481B1 (no) 1990-10-16 1998-03-09 Takeda Chemical Industries Ltd Polymer for et preparat med forlenget frigjöring, samt preparat med forlenget frigjöring
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
US5518730A (en) * 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
EP0582459B1 (en) 1992-08-07 1998-01-07 Takeda Chemical Industries, Ltd. Production of microcapsules of water-soluble drugs
ATE211655T1 (de) 1993-09-22 2002-01-15 Hisamitsu Pharmaceutical Co Iontophoresematrix
DE69508985T2 (de) * 1994-02-21 1999-08-19 Takeda Chemical Industries Polyester Matrix für eine pharmazeutische Zusammensetzung mit verzögerter Freigabe
US6117455A (en) 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
IL115099A (en) * 1994-10-14 1999-04-11 Upjohn Co Lyophilizate of phospholipid complex of water insoluble camptothecins
US5837281A (en) 1995-03-17 1998-11-17 Takeda Chemical Industries, Ltd. Stabilized interface for iontophoresis
CA2192782C (en) 1995-12-15 2008-10-14 Nobuyuki Takechi Production of microspheres
CA2192773C (en) 1995-12-15 2008-09-23 Hiroaki Okada Production of sustained-release preparation for injection
CN1095681C (zh) * 1996-06-20 2002-12-11 久光制药株式会社 一种用于离子电渗疗法的装置结构
US20070274946A1 (en) * 1999-04-15 2007-11-29 Norwood Immunoloty, Ltd. Tolerance to Graft Prior to Thymic Reactivation
US20040241842A1 (en) * 1999-04-15 2004-12-02 Monash University Stimulation of thymus for vaccination development
US20040259803A1 (en) * 1999-04-15 2004-12-23 Monash University Disease prevention by reactivation of the thymus
US20040258672A1 (en) * 1999-04-15 2004-12-23 Monash University Graft acceptance through manipulation of thymic regeneration
AUPR074500A0 (en) * 2000-10-13 2000-11-09 Monash University Treatment of t cell disorders
US20050042679A1 (en) * 1999-04-15 2005-02-24 Monash University Diagnostic indicator of thymic function
US20040265285A1 (en) * 1999-04-15 2004-12-30 Monash University Normalization of defective T cell responsiveness through manipulation of thymic regeneration
US20050020524A1 (en) * 1999-04-15 2005-01-27 Monash University Hematopoietic stem cell gene therapy
DE60031133T2 (de) * 1999-06-30 2007-04-12 Takeda Pharmaceutical Co. Ltd. Verfahren zur darstellung von lh-rh-derivaten
JP4414517B2 (ja) 1999-09-01 2010-02-10 久光製薬株式会社 イオントフォレーシス用デバイス構造体
US20060088512A1 (en) * 2001-10-15 2006-04-27 Monash University Treatment of T cell disorders
BR0115260A (pt) * 2000-11-09 2005-08-16 Neopharm Inc Complexos de sn-38 com lipìdeos e seus usos no tratamento de doenças
WO2003030864A1 (en) * 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
WO2004035032A2 (en) * 2002-08-20 2004-04-29 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
PT1684782E (pt) 2003-10-03 2015-12-21 Thorn Bioscience Llc Processo para a sincronização da ovulação para reprodução regulada sem detecção do cio
GB0326632D0 (en) 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
US20080279812A1 (en) * 2003-12-05 2008-11-13 Norwood Immunology, Ltd. Disease Prevention and Vaccination Prior to Thymic Reactivation
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
ES2336826T3 (es) 2005-05-03 2010-04-16 Novetide, Ltd. Procedimientos para la produccion de un peptido que presenta una amida c-terminal.
EP1790656A1 (en) 2005-11-25 2007-05-30 Nanokem S.A. Solution-phase synthesis of leuprolide
US20070197435A1 (en) * 2006-02-17 2007-08-23 Webel Stephen K Process for the synchronization of ovulation for timed breeding without heat detection
CN104906556A (zh) 2009-04-23 2015-09-16 Jbs联合动物健康二有限公司 用于同步授精时间的方法和组合物
JP5927175B2 (ja) 2010-04-01 2016-06-01 シエシー ファルマセウティチィ ソシエタ ペル アチオニ ドライパウダー状の吸入用医薬組成物、担体粒子および医薬品の製造方法
WO2011148384A1 (en) 2010-05-07 2011-12-01 Matrix Laboratories Ltd Novel process for the preparation of leuprolide and its pharmaceutically acceptable salts thereof
WO2012028745A1 (en) 2010-09-03 2012-03-08 Pharmaterials Limited Pharmaceutical composition suitable for use in a dry powder inhaler
BR112015012453A8 (pt) 2012-11-28 2021-06-29 Jbs United Animal Health Ii Llc métodos e usos para sincronizar o tempo de ovulação e de inseminação em uma leitoa
CN103012564B (zh) * 2013-01-15 2013-11-13 成都天台山制药有限公司 高纯度的曲普瑞林及其纯化方法
CN103012565B (zh) * 2013-01-15 2014-07-16 成都天台山制药有限公司 一种曲普瑞林及其固相合成制备方法
CN104402977B (zh) * 2014-12-08 2017-11-14 泰州启瑞医药科技有限公司 一种布舍瑞林的固液合成方法
US20190298836A1 (en) 2016-11-02 2019-10-03 Board Of Regents, The University Of Texas System Dissolvable films and methods of their use
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO139560C (no) * 1972-04-29 1979-04-04 Takeda Chemical Industries Ltd Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater
US3914412A (en) * 1973-10-11 1975-10-21 Abbott Lab {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity

Also Published As

Publication number Publication date
DK148305C (da) 1985-12-02
NL179289B (nl) 1986-03-17
DK148305B (da) 1985-06-03
HU173783B (hu) 1979-08-28
GB1434694A (en) 1976-05-05
NL930015I2 (nl) 1993-11-01
ES430495A1 (es) 1977-01-16
FI61028B (fi) 1982-01-29
NL7412837A (nl) 1975-04-02
NL930015I1 (nl) 1993-05-03
FI61028C (fi) 1982-05-10
NO1994010I1 (no) 1994-08-18
DE2446005A1 (de) 1975-04-03
ATA772674A (de) 1978-04-15
FR2245375A1 (da) 1975-04-25
SE420717B (sv) 1981-10-26
SE7412140L (da) 1975-04-01
FI284774A (da) 1975-03-30
CH603559A5 (da) 1978-08-31
US4008209A (en) 1977-02-15
HK15579A (en) 1979-03-30
NO143218B (no) 1980-09-22
AT347054B (de) 1978-12-11
DK510374A (da) 1975-05-26
NO743538L (da) 1975-04-28
CA1027114A (en) 1978-02-28
CS180644B2 (en) 1978-01-31
BE820451A (fr) 1975-03-27
FR2245375B1 (da) 1978-07-21
DE2446005C2 (de) 1982-03-18
NL179289C (nl) 1986-08-18
NL930121I1 (nl) 1993-11-01

Similar Documents

Publication Publication Date Title
NO143218C (no) Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet
NO145273C (no) N-formyl-alfa-l-aspartyl-l-fenylalanin for anvendelse til fremstilling av alfa-l-aspartyl-l-fenylalaninalkylestere
SE423631B (sv) Forfarande for framstellning av oxaalhyl-dialkylxantiner
SE7710599L (sv) Forfarande for framstellning av bensisoxazoler
NO149281C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 7alfa-metoksycephalosporinderivater
SE411212B (sv) Forfarande for framstellning av 3-halogen-cefalosporiner
SE420604B (sv) Forfarande for framstellning av oxazolderivat
NO141850C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive pyrazolderivater.
NO146596C (no) Fremgangsmaate for fremstilling av 6-deoksytetracykliner
NO141649C (no) Analogifremgangsmaate for fremstilling av neuroleptisk aktive 7-fluorsubstituerte fenotiaziner
SE7712151L (sv) Forfarande for framstellning av linkomycinderivat
NO141755C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme dotriacontapeptidamider
SE417601B (sv) Forfarande for framstellning av amidinokarbamider
NO790627L (no) Fremgangsmaate for fremstilling av hydroksyalkylxantiner
NO843825L (no) Fremgangsmaate for fremstilling av 6-deoksytetracyklin
SE417319B (sv) Analogiforfarande for framstellning av ergopeptiner
NO148376C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 7-acylamino-3-halogen-cefalosporinforbindelser
SE409994B (sv) Forfarande for framstellning av amidinokarbamider
SE7613500L (sv) Forfarande for framstellning av cefemderivat
SE401835B (sv) Forfarande for framstellning av 17beta-hydroxi-16,16-dimetylest-4-en-3-on
NO143845C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-amino-pyrrolderivater
SE406086B (sv) Forfarande for framstellning av cyklisk-dikarboximido-substituerade fosfonotioater
NO141410C (no) Analogifremgangsmaate til fremstilling av beta-adrenergisk blokkerende aminopropanoler
SE409325B (sv) Forfarande for framstellning av kinazolinonderivat
NO146597C (no) Fremgangsmaate for fremstilling av 6-metylentetracykliner