MA25391A1 - Inhibiteurs d'alcenyl et alcynyl metalloproteases. - Google Patents

Inhibiteurs d'alcenyl et alcynyl metalloproteases.

Info

Publication number
MA25391A1
MA25391A1 MA26310A MA26310A MA25391A1 MA 25391 A1 MA25391 A1 MA 25391A1 MA 26310 A MA26310 A MA 26310A MA 26310 A MA26310 A MA 26310A MA 25391 A1 MA25391 A1 MA 25391A1
Authority
MA
Morocco
Prior art keywords
alcynyl
alcenyl
metalloproteases inhibitors
metalloproteases
inhibitors
Prior art date
Application number
MA26310A
Other languages
English (en)
Inventor
Gunnard Bookland Roger
Gregory Almstead Neil
De Biswanath
George Natchus Michael
Pikul Stanislaw
Cheng Menyan
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MA25391A1 publication Critical patent/MA25391A1/fr

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
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MA26310A 1999-03-03 2001-09-03 Inhibiteurs d'alcenyl et alcynyl metalloproteases. MA25391A1 (fr)

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HK1044754A1 (zh) 2002-11-01
EP1165501A1 (fr) 2002-01-02
CN1349498A (zh) 2002-05-15
WO2000051975A1 (fr) 2000-09-08
PE20001565A1 (es) 2001-02-02
KR20010102486A (ko) 2001-11-15
AU3386000A (en) 2000-09-21
US6197770B1 (en) 2001-03-06
JP2002538136A (ja) 2002-11-12
RU2001126721A (ru) 2004-02-20
BR0008716A (pt) 2002-09-24
NO20014242L (no) 2001-09-27
SK12452001A3 (sk) 2002-04-04
AU764051B2 (en) 2003-08-07
ZA200106967B (en) 2002-03-13
HUP0202199A2 (en) 2002-10-28
NZ513831A (en) 2001-09-28
CZ20013176A3 (cs) 2002-04-17
TR200102523T2 (tr) 2002-02-21
CO5150219A1 (es) 2002-04-29
IL145089A0 (en) 2002-06-30
MXPA01008855A (es) 2002-07-02

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