IL65247A - Derivatives of n-acyltetra-hydroquinoline,isoquinoline,benzazepine and benzazocine carboxylic acids,process for their preparation and pharmaceutical compositions containing them - Google Patents

Derivatives of n-acyltetra-hydroquinoline,isoquinoline,benzazepine and benzazocine carboxylic acids,process for their preparation and pharmaceutical compositions containing them

Info

Publication number: IL65247A
Authority: IL; Israel
Prior art keywords: acyltetra; benzazocine; hydroquinoline; benzazepine; isoquinoline
Prior art date: 1981-03-19

Application number

IL65247A

Other languages

English (en)

Other versions

IL65247A0 (en

Original Assignee

Usv Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-19

Filing date

1982-03-15

Publication date

1987-07-31

1982-03-15 Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp

1982-05-31 Publication of IL65247A0 publication Critical patent/IL65247A0/xx

1987-07-31 Publication of IL65247A publication Critical patent/IL65247A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

IL65247A 1981-03-19 1982-03-15 Derivatives of n-acyltetra-hydroquinoline,isoquinoline,benzazepine and benzazocine carboxylic acids,process for their preparation and pharmaceutical compositions containing them IL65247A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US24540781A	1981-03-19	1981-03-19

Publications (2)

Publication Number	Publication Date
IL65247A0 IL65247A0 (en)	1982-05-31
IL65247A true IL65247A (en)	1987-07-31

Family

ID=22926526

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL65247A IL65247A (en)	1981-03-19	1982-03-15	Derivatives of n-acyltetra-hydroquinoline,isoquinoline,benzazepine and benzazocine carboxylic acids,process for their preparation and pharmaceutical compositions containing them

Country Status (21)

Country	Link
JP (1)	JPS57165355A (el)
KR (1)	KR890001146B1 (el)
AU (1)	AU558451B2 (el)
BE (1)	BE892552A (el)
CH (1)	CH658455A5 (el)
DE (1)	DE3209708A1 (el)
DK (1)	DK120982A (el)
ES (3)	ES510498A0 (el)
FI (1)	FI820974L (el)
FR (1)	FR2502149A1 (el)
GB (1)	GB2095252B (el)
IE (1)	IE53076B1 (el)
IL (1)	IL65247A (el)
IN (1)	IN156096B (el)
IT (1)	IT1150697B (el)
NL (1)	NL8201066A (el)
NO (1)	NO820903L (el)
NZ (1)	NZ200047A (el)
PH (1)	PH18657A (el)
SE (1)	SE8201654L (el)
ZA (1)	ZA821833B (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3242599A1 (de) *	1982-11-18	1984-05-24	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel
US4410520A (en) *	1981-11-09	1983-10-18	Ciba-Geigy Corporation	3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4555502A (en) *	1982-09-30	1985-11-26	Merck & Co., Inc.	Aminoacyl-containing dipeptide derivatives useful as antihypertensives
US4410807A (en) *	1982-03-26	1983-10-18	Kay Industries, Inc.	Regulating device for polyphase electrical circuits
US4473575A (en) *	1982-07-19	1984-09-25	Ciba-Geigy Corporation	3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
US4520025A (en) *	1982-07-21	1985-05-28	William H. Rorer, Inc.	Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
DE3302125A1 (de) *	1983-01-22	1984-07-26	Boehringer Ingelheim KG, 6507 Ingelheim	Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung
DK156484A (da) *	1983-03-16	1984-09-17	Usv Pharma Corp	Aminosyrederivater
DE3333454A1 (de) *	1983-09-16	1985-04-11	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3622297A1 (de) *	1986-07-03	1988-01-07	Basf Ag	Disazothiophenfarbstoffe
US5246943A (en) *	1992-05-19	1993-09-21	Warner-Lambert Company	Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
ES2122941B1 (es) *	1997-05-29	1999-07-01	Esteve Quimica Sa	Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato.
ATE365714T1 (de) *	2002-01-30	2007-07-15	Servier Lab	Verfahren zur herstellung von hochreinem perindopril und zwischenverbindungen nützlich in der synthese
DK1572661T5 (da)	2002-12-16	2007-11-05	Lupin Ltd	Krystallinsk form af quinaprilhydrochlorid og fremgangsmåde til fremstilling af samme
US7521566B2 (en) *	2003-02-28	2009-04-21	Les Laboratoires Servier	Process for preparation of perindopril and salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2503155A2 (fr) *	1980-10-02	1982-10-08	Science Union & Cie	Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
EP0278530A3 (de) *	1980-08-30	1989-08-02	Hoechst Aktiengesellschaft	Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung
US4344949A (en) *	1980-10-03	1982-08-17	Warner-Lambert Company	Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
GB2086390B (en) *	1980-11-03	1984-06-06	Ciba Geigy Ag	1-carboxy-azaalkanoylindoline-2-carboxylic acids process for their manufacture pharmaceutical preparations containing these compounds and their therapeutic application

1982
- 1982-03-08 IN IN265/CAL/82A patent/IN156096B/en unknown
- 1982-03-15 IL IL65247A patent/IL65247A/xx unknown
- 1982-03-15 NL NL8201066A patent/NL8201066A/nl not_active Application Discontinuation
- 1982-03-15 PH PH26998A patent/PH18657A/en unknown
- 1982-03-16 AU AU81584/82A patent/AU558451B2/en not_active Ceased
- 1982-03-16 SE SE8201654A patent/SE8201654L/xx not_active Application Discontinuation
- 1982-03-17 GB GB8207770A patent/GB2095252B/en not_active Expired
- 1982-03-17 DE DE19823209708 patent/DE3209708A1/de not_active Withdrawn
- 1982-03-17 ES ES510498A patent/ES510498A0/es active Granted
- 1982-03-18 DK DK120982A patent/DK120982A/da not_active Application Discontinuation
- 1982-03-18 NZ NZ200047A patent/NZ200047A/en unknown
- 1982-03-18 IT IT20259/82A patent/IT1150697B/it active
- 1982-03-18 JP JP57041801A patent/JPS57165355A/ja active Pending
- 1982-03-18 CH CH1691/82A patent/CH658455A5/de not_active IP Right Cessation
- 1982-03-18 KR KR8201157A patent/KR890001146B1/ko active
- 1982-03-18 NO NO820903A patent/NO820903L/no unknown
- 1982-03-18 BE BE0/207610A patent/BE892552A/fr not_active IP Right Cessation
- 1982-03-18 ZA ZA821833A patent/ZA821833B/xx unknown
- 1982-03-19 FI FI820974A patent/FI820974L/fi not_active Application Discontinuation
- 1982-03-19 IE IE635/82A patent/IE53076B1/en unknown
- 1982-03-19 FR FR8204738A patent/FR2502149A1/fr active Granted
1983
- 1983-03-16 ES ES521031A patent/ES521031A0/es active Granted
- 1983-03-16 ES ES521030A patent/ES8404317A1/es not_active Expired

Also Published As

Publication number	Publication date
ES521030A0 (es)	1984-05-16
KR890001146B1 (ko)	1989-04-25
NO820903L (no)	1982-09-20
FR2502149B1 (el)	1985-01-18
PH18657A (en)	1985-08-29
ES8501363A1 (es)	1984-12-01
DK120982A (da)	1982-09-20
NL8201066A (nl)	1982-10-18
FI820974L (fi)	1982-09-20
ES8307718A1 (es)	1983-08-01
JPS57165355A (en)	1982-10-12
IE53076B1 (en)	1988-06-08
AU558451B2 (en)	1987-01-29
ES521031A0 (es)	1984-12-01
GB2095252A (en)	1982-09-29
IT1150697B (it)	1986-12-17
CH658455A5 (de)	1986-11-14
IE820635L (en)	1982-09-19
ZA821833B (en)	1983-01-26
KR830009065A (ko)	1983-12-17
SE8201654L (sv)	1982-09-20
FR2502149A1 (fr)	1982-09-24
DE3209708A1 (de)	1982-10-21
ES8404317A1 (es)	1984-05-16
IN156096B (el)	1985-05-11
IL65247A0 (en)	1982-05-31
AU8158482A (en)	1982-09-23
GB2095252B (en)	1985-04-17
IT8220259A0 (it)	1982-03-18
BE892552A (fr)	1982-09-20
NZ200047A (en)	1985-07-12
ES510498A0 (es)	1983-08-01

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