US3773319A
(en)
|
1971-12-16 |
1973-11-20 |
Fabcor Ind Inc |
Corrugated sheet inverting machine
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
US4510245A
(en)
|
1982-11-18 |
1985-04-09 |
Chiron Corporation |
Adenovirus promoter system
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
HUT35524A
(en)
|
1983-08-02 |
1985-07-29 |
Hoechst Ag |
Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
|
US6054561A
(en)
|
1984-02-08 |
2000-04-25 |
Chiron Corporation |
Antigen-binding sites of antibody molecules specific for cancer antigens
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
US4694778A
(en)
|
1984-05-04 |
1987-09-22 |
Anicon, Inc. |
Chemical vapor deposition wafer boat
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
WO1986005807A1
(en)
|
1985-04-01 |
1986-10-09 |
Celltech Limited |
Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
|
US4968615A
(en)
|
1985-12-18 |
1990-11-06 |
Ciba-Geigy Corporation |
Deoxyribonucleic acid segment from a virus
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
US4902505A
(en)
|
1986-07-30 |
1990-02-20 |
Alkermes |
Chimeric peptides for neuropeptide delivery through the blood-brain barrier
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5116742A
(en)
|
1986-12-03 |
1992-05-26 |
University Patents, Inc. |
RNA ribozyme restriction endoribonucleases and methods
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
US5336603A
(en)
|
1987-10-02 |
1994-08-09 |
Genentech, Inc. |
CD4 adheson variants
|
WO1989006692A1
(en)
|
1988-01-12 |
1989-07-27 |
Genentech, Inc. |
Method of treating tumor cells by inhibiting growth factor receptor function
|
GB8809129D0
(en)
|
1988-04-18 |
1988-05-18 |
Celltech Ltd |
Recombinant dna methods vectors and host cells
|
AU631802B2
(en)
|
1988-06-14 |
1992-12-10 |
Cetus Oncology Corporation |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
IL91501A
(en)
|
1988-09-02 |
1998-03-10 |
Dyax Corp |
Generation of a variegated library of mutant potential binding proteins and screening of said library for proteins with a desired binding activity
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
ATE102631T1
(de)
|
1988-11-11 |
1994-03-15 |
Medical Res Council |
Klonierung von immunglobulin sequenzen aus den variabelen domaenen.
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
WO1990006952A1
(en)
|
1988-12-22 |
1990-06-28 |
Kirin-Amgen, Inc. |
Chemically modified granulocyte colony stimulating factor
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
ZA902949B
(en)
|
1989-05-05 |
1992-02-26 |
Res Dev Foundation |
A novel antibody delivery system for biological response modifiers
|
DE69031120T2
(de)
|
1989-05-19 |
1998-01-15 |
Genentech, Inc., South San Francisco, Calif. |
Her2 extrazellulare domäne
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
US5180820A
(en)
|
1989-08-30 |
1993-01-19 |
Barde Yves Alain |
Brain-derived neurotrophic factor
|
US5605690A
(en)
|
1989-09-05 |
1997-02-25 |
Immunex Corporation |
Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
AU7247191A
(en)
|
1990-01-11 |
1991-08-05 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
WO1996033735A1
(en)
|
1995-04-27 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5314995A
(en)
|
1990-01-22 |
1994-05-24 |
Oncogen |
Therapeutic interleukin-2-antibody based fusion proteins
|
EP0521985B1
(en)
|
1990-03-20 |
1997-09-24 |
The Trustees Of Columbia University In The City Of New York |
Chimeric antibodies with receptor binding ligands in place of their constant region
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US5219837A
(en)
*
|
1990-06-21 |
1993-06-15 |
Trustees Of The University Of Pennsylvania |
Method of stimulating myelination of cells
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5532351A
(en)
|
1990-07-12 |
1996-07-02 |
Arch Development Corporation |
Nucleic acid sequences encoding OMGP
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
AU8507191A
(en)
|
1990-08-29 |
1992-03-30 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
WO1992008495A1
(en)
|
1990-11-09 |
1992-05-29 |
Abbott Biotech, Inc. |
Cytokine immunoconjugates
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
ATE269401T1
(de)
|
1991-04-10 |
2004-07-15 |
Scripps Research Inst |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
EP0590067A1
(en)
|
1991-06-14 |
1994-04-06 |
Xoma Corporation |
Microbially-produced antibody fragments and their conjugates
|
IE922437A1
(en)
|
1991-07-25 |
1993-01-27 |
Idec Pharma Corp |
Recombinant antibodies for human therapy
|
US5756096A
(en)
|
1991-07-25 |
1998-05-26 |
Idec Pharmaceuticals Corporation |
Recombinant antibodies for human therapy
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
ATE244763T1
(de)
|
1992-02-11 |
2003-07-15 |
Cell Genesys Inc |
Erzielen von homozygotem durch zielgerichtete genetische ereignisse
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
CA2126967A1
(en)
|
1992-11-04 |
1994-05-11 |
Anna M. Wu |
Novel antibody construct
|
EP0669986B1
(en)
|
1992-11-13 |
2003-04-09 |
Idec Pharmaceuticals Corporation |
Fully impaired consensus kozac sequences for mammalian expression
|
US5468872A
(en)
|
1993-09-16 |
1995-11-21 |
Cephalon, Inc. |
K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders
|
DK0730740T3
(da)
|
1993-11-23 |
1998-09-28 |
Genentech Inc |
Kinasereceptoraktiveringsassay
|
US5753225A
(en)
|
1993-12-03 |
1998-05-19 |
The Regents Of The University Of California |
Antibodies that mimic actions of neurotrophins
|
AU696293B2
(en)
|
1993-12-08 |
1998-09-03 |
Genzyme Corporation |
Process for generating specific antibodies
|
ATE300610T1
(de)
|
1994-01-31 |
2005-08-15 |
Univ Boston |
Bibliotheken aus polyklonalen antikörpern
|
GB9402331D0
(en)
|
1994-02-07 |
1994-03-30 |
Univ Mcgill |
Nerve growth factor structural analogs and their uses
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
DE4447588C2
(de)
|
1994-05-03 |
1997-11-20 |
Omer Osama Dr Dr Med |
Pflanzliches Arzneimittel zur Behandlung von chronischen und allergischen Rhino-Sino-Bronchitiden
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
WO2001004311A1
(en)
|
1999-07-07 |
2001-01-18 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
DE69531877T2
(de)
|
1994-10-25 |
2004-07-29 |
Toyama Chemical Co. Ltd. |
Ein Wirkstoff für die Forderung von Nervwachstumfaktor Aktivität, der ein 1,2-Ethandiol-Derivat oder ein Salz davon enthält
|
US5770577A
(en)
|
1994-11-14 |
1998-06-23 |
Amgen Inc. |
BDNF and NT-3 polypeptides selectively linked to polyethylene glycol
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
US6280964B1
(en)
|
1995-04-14 |
2001-08-28 |
The Regents Of The University Of California |
Binding sites for phosphotyrosine binding domains
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5811524A
(en)
|
1995-06-07 |
1998-09-22 |
Idec Pharmaceuticals Corporation |
Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
|
AU6113396A
(en)
|
1995-06-14 |
1997-01-15 |
Regents Of The University Of California, The |
Novel high affinity human antibodies to tumor antigens
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
IT235676Y1
(it)
|
1995-07-27 |
2000-07-12 |
Felice Gaudioso |
Allestimenti per lo svolgimento del gioco wormhole action match.
|
GB9525180D0
(en)
|
1995-12-08 |
1996-02-07 |
Univ Mcgill |
Design of hormone-like antibodies with agonistic and antagonistic fuctions
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
US6455277B1
(en)
|
1996-04-22 |
2002-09-24 |
Amgen Inc. |
Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides
|
JP2000501416A
(ja)
|
1996-04-26 |
2000-02-08 |
ユニバーシティー オブ オタワ |
ニューロン病を治療し予防するための、治療法および薬物のスクリーニング法
|
DK0912184T3
(da)
|
1996-06-25 |
2002-11-25 |
Cephalon Inc |
Anvendelse af K-252a-derivat til behandlingen af perifere eller centrale nervelidelser og cytokinoverproduktion
|
IL127891A0
(en)
|
1996-07-12 |
1999-10-28 |
Genentech Inc |
Chimeric heteromultimeter adhesins
|
CA2259163C
(en)
|
1996-07-19 |
2004-07-06 |
Amgen Inc. |
Nt-3 and bdnf analogs having improved circulating life and/or absorption
|
CA2264966A1
(en)
|
1996-09-11 |
1998-03-19 |
The General Hospital Corporation |
Expression of an exogenous gene in a mammalian cell by use of a non-mammalian dna virus having an altered coat protein
|
KR100514277B1
(ko)
|
1996-09-13 |
2005-09-13 |
유겐가이샤 사이센딴이가꾸겡꾸쇼 |
신경 영양 인자의 안과용 조성물, 시신경 기능 장애 치료제 및 시신경 기능 장애 치료 방법
|
US6420140B1
(en)
|
1996-10-11 |
2002-07-16 |
Abgenix, Inc. |
Production of multimeric protein by cell fusion method
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
US20070213290A1
(en)
|
1996-10-17 |
2007-09-13 |
Kingsman Alan J |
Neurite regeneration
|
US6156728A
(en)
|
1996-11-01 |
2000-12-05 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
US6593290B1
(en)
|
1996-11-01 |
2003-07-15 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
EP2305027B1
(en)
|
1996-12-03 |
2014-07-02 |
Amgen Fremont Inc. |
Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom
|
DE69830312T2
(de)
|
1997-03-14 |
2006-02-02 |
Biogen Idec Inc., San Diego |
Methode zur spezifischen integration von genen in säugetierzellen durch homologe rekombination, und vektoren zu deren durchführung
|
US20020137890A1
(en)
|
1997-03-31 |
2002-09-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
DK0970126T3
(da)
|
1997-04-14 |
2001-08-13 |
Micromet Ag |
Hidtil ukendt fremgangsmåde til fremstillingen af anti-humant antigen-receptorer og anvendelser deraf
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
EP0983303B1
(en)
|
1997-05-21 |
2006-03-08 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
US6190370B1
(en)
|
1997-07-25 |
2001-02-20 |
Arrow International, Inc. |
Devices, systems and methods for determining proper placement of epidural catheters
|
JP2001512003A
(ja)
|
1997-08-04 |
2001-08-21 |
ミレニアム ファーマシューティカルズ インク. |
Tango−78、Tango−79およびTango−81ポリペプチド、Tango−78、Tango−79およびTango−81をコードする核酸分子ならびにそれらの使用
|
US20020112251A1
(en)
|
1997-08-04 |
2002-08-15 |
Mccarthy Sean A. |
Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic and other uses
|
AU741060C
(en)
|
1997-09-17 |
2002-09-19 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6974689B1
(en)
|
1997-09-18 |
2005-12-13 |
Genentech, Inc. |
Nucleic acid encoding PRO211 polypeptides
|
DE69832539T2
(de)
|
1997-10-24 |
2006-07-20 |
Genentech, Inc., South San Francisco |
Polypeptid und dafür kodierendes Nukeinsäure
|
FR2776661B1
(fr)
|
1998-03-26 |
2002-04-05 |
Centre Nat Rech Scient |
Polypeptide immunoreactif du recepteur trka du ngf et utilisations
|
US7282482B2
(en)
|
1998-04-08 |
2007-10-16 |
The Regents Of The University Of California |
NGF for the prevention of demyelination in the nervous system
|
MXPA01002592A
(es)
|
1998-09-16 |
2004-06-07 |
Genentech Inc |
Polipeptidos de transmembrana y secretados y acidos nucleicos que codifican los mismos.
|
JP2003531566A
(ja)
|
1998-11-06 |
2003-10-28 |
シュヴァブ,マーティン,イー. |
Nogo遺伝子のヌクレオチド配列およびタンパク質配列、ならびにそれに基づく方法
|
AU776910B2
(en)
|
1998-12-08 |
2004-09-23 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
Modifying protein immunogenicity
|
US7034132B2
(en)
|
2001-06-04 |
2006-04-25 |
Anderson David W |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US20040067490A1
(en)
|
2001-09-07 |
2004-04-08 |
Mei Zhong |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
EP1189931B1
(en)
|
1999-07-02 |
2006-06-21 |
Genentech, Inc. |
Peptide compounds that bind her2
|
EP1074617A3
(en)
|
1999-07-29 |
2004-04-21 |
Research Association for Biotechnology |
Primers for synthesising full-length cDNA and their use
|
WO2001009317A1
(fr)
|
1999-07-29 |
2001-02-08 |
Helix Research Institute |
Gene associe au cancer de l'estomac
|
EP1206543A2
(en)
|
1999-08-17 |
2002-05-22 |
Incyte Genomics, Inc. |
Membrane associated proteins
|
US6461414B1
(en)
|
1999-10-29 |
2002-10-08 |
Baker Hughes Incorporated |
Foam monitoring and control system
|
CA2491610A1
(en)
|
1999-12-01 |
2001-06-07 |
Kevin P. Baker |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6680209B1
(en)
|
1999-12-06 |
2004-01-20 |
Biosite, Incorporated |
Human antibodies as diagnostic reagents
|
US20040252299A9
(en)
*
|
2000-01-07 |
2004-12-16 |
Lemmo Anthony V. |
Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions
|
ATE466882T1
(de)
|
2000-01-12 |
2010-05-15 |
Univ Yale |
Nogo rezeptor-vermittelte blockade des axonalen wachstums
|
US7119165B2
(en)
*
|
2000-01-12 |
2006-10-10 |
Yale University |
Nogo receptor-mediated blockade of axonal growth
|
WO2001052843A1
(en)
|
2000-01-18 |
2001-07-26 |
Mcgill University |
β-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS
|
WO2001055333A2
(en)
|
2000-01-25 |
2001-08-02 |
Hyseq, Inc. |
Methods and materials relating to transforming growth factor alpha-like polypeptides and polynucleotides
|
CA2395827A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
CA2393616A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
WO2001059063A2
(en)
|
2000-01-31 |
2001-08-16 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
AU2001236663A1
(en)
|
2000-02-03 |
2001-08-14 |
Nuvelo, Inc. |
Methods and materials relating to neuronal guidance molecule-like (ngm-like) polypeptides and polynucleotides
|
CN1426422A
(zh)
|
2000-02-29 |
2003-06-25 |
株式会社Ltt研究所 |
修饰的bdnf
|
DK1272647T3
(en)
|
2000-04-11 |
2014-12-15 |
Genentech Inc |
Multivalent antibodies and uses thereof
|
AU2001266787A1
(en)
|
2000-06-07 |
2002-01-08 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
US6430914B1
(en)
|
2000-06-29 |
2002-08-13 |
Foster Wheeler Energy Corporation |
Combined cycle power generation plant and method of operating such a plant
|
US20040010118A1
(en)
|
2000-08-16 |
2004-01-15 |
Zerhusen Bryan D. |
Novel proteins and nucleic acids encoding same
|
CA2421303A1
(en)
|
2000-09-13 |
2002-03-21 |
Smithkline Beecham Corporation |
Novel compounds
|
WO2002029058A2
(en)
|
2000-10-05 |
2002-04-11 |
Curagen Corporation |
Human proteins, polynucleotides encoding them and methods of using the same
|
US20030124704A1
(en)
|
2000-10-06 |
2003-07-03 |
Strittmatter Stephen M. |
Nogo receptor homologs
|
AU2001297872B2
(en)
|
2000-11-17 |
2006-11-09 |
University Of Rochester |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
ES2295218T3
(es)
|
2000-12-01 |
2008-04-16 |
Central Institute For Experimental Animals |
Procedimiento para la produccion de un raton adecuado para el prendimiento, la diferenciacion y la proliferacion de celulas heterogeneas, raton producido mediante este procedimiento y utilizacion del raton.
|
US20030216558A1
(en)
|
2000-12-22 |
2003-11-20 |
Morris David W. |
Novel compositions and methods for cancer
|
WO2002068579A2
(en)
|
2001-01-10 |
2002-09-06 |
Pe Corporation (Ny) |
Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof
|
AU2002240120B2
(en)
|
2001-01-29 |
2008-05-08 |
Biogen Idec Inc. |
Modified antibodies and methods of use
|
US7319139B2
(en)
|
2001-01-29 |
2008-01-15 |
Biogen Idec, Inc. |
TAG-72 specific CH2 domain deleted antibodies
|
WO2003008583A2
(en)
|
2001-03-02 |
2003-01-30 |
Sagres Discovery |
Novel compositions and methods for cancer
|
WO2002099116A2
(en)
|
2001-06-04 |
2002-12-12 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
US20030162734A1
(en)
|
2001-06-28 |
2003-08-28 |
Miller Carol A. |
Modulation of DENN-MADD expression and interactions for treating neurological disorders
|
US7223558B2
(en)
|
2001-07-11 |
2007-05-29 |
Bristol-Myers Squibb Company |
Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof
|
US20030226155A1
(en)
|
2001-08-30 |
2003-12-04 |
Biorexis Pharmaceutical Corporation |
Modified transferrin-antibody fusion proteins
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
US20050123990A1
(en)
|
2001-09-26 |
2005-06-09 |
Incyte Corporation |
Membrane associated proteins
|
US7098302B2
(en)
|
2001-10-12 |
2006-08-29 |
University Of Vermont And State Agricultural College |
Binding peptides specific for the extracellular domain of ErbB2 and uses therefor
|
AU2002337916A1
(en)
|
2001-10-22 |
2003-05-06 |
Exelixis, Inc. |
Modifier of the p53 pathway and methods of use
|
US7309485B2
(en)
|
2001-12-03 |
2007-12-18 |
Children's Medical Center Corporation |
Reducing myelin-mediated inhibition of axon regeneration
|
EP1504099A4
(en)
|
2001-12-10 |
2006-05-10 |
Nuvelo Inc |
NEW NUCLEIC ACIDS AND POLYPEPTIDES
|
WO2003074674A2
(en)
|
2002-03-01 |
2003-09-12 |
Exelixis, Inc. |
MSRAs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
AU2003243139B2
(en)
|
2002-04-05 |
2007-06-21 |
Amgen Inc. |
Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
|
US7077522B2
(en)
|
2002-05-03 |
2006-07-18 |
University Of Rochester |
Sharpness metric for vision quality
|
US6794785B2
(en)
|
2002-06-26 |
2004-09-21 |
Denso Corporation |
Alternator for vehicles
|
RS20050129A
(xx)
|
2002-08-10 |
2007-06-04 |
Yale University, |
Antagonisti nogo receptora
|
EA033750B1
(ru)
|
2002-09-06 |
2019-11-21 |
Amgen Inc |
Изолированная молекула нуклеиновой кислоты, кодирующая антитело человека к рецептору интерлейкина-1, и ее применение
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
US7816497B2
(en)
|
2002-10-30 |
2010-10-19 |
University Of Kentucky |
Compositions and methods for inhibiting drusen complement components C3a and C5a for the treatment of age-related macular degeneration
|
US20040186044A1
(en)
|
2002-11-06 |
2004-09-23 |
Cosgaya Jose Miguel |
Modulation of myelination by interaction with P75 and TRK receptors
|
US7388079B2
(en)
|
2002-11-27 |
2008-06-17 |
The Regents Of The University Of California |
Delivery of pharmaceutical agents via the human insulin receptor
|
PL2248899T3
(pl)
|
2003-03-19 |
2015-10-30 |
Biogen Ma Inc |
Białko wiążące receptor nogo
|
AU2004264405A1
(en)
|
2003-08-07 |
2005-02-24 |
Biogen Idec Ma Inc. |
Nogo receptor antagonists
|
AU2004266159A1
(en)
|
2003-08-22 |
2005-03-03 |
Biogen Idec Ma Inc. |
Improved antibodies having altered effector function and methods for making the same
|
US7205387B2
(en)
|
2003-08-28 |
2007-04-17 |
Agency For Science, Technology And Research |
Recombinant polypeptide useful for neurotrophin receptor mediated gene delivery and as neurotrophin agonist
|
JP2007512001A
(ja)
|
2003-08-28 |
2007-05-17 |
バイオレクシス ファーマシューティカル コーポレイション |
Epoミメティックペプチドおよび融合タンパク質
|
US7288638B2
(en)
|
2003-10-10 |
2007-10-30 |
Bristol-Myers Squibb Company |
Fully human antibodies against human 4-1BB
|
ATE536376T1
(de)
|
2003-12-23 |
2011-12-15 |
Crucell Holland Bv |
Humanes bindungsmolekül gegen cd1a
|
JP2007527712A
(ja)
|
2004-02-12 |
2007-10-04 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規な遺伝子破壊、これに関する組成物と方法
|
US20050214288A1
(en)
*
|
2004-03-26 |
2005-09-29 |
Human Genome Sciences, Inc. |
Antibodies against Nogo receptor
|
WO2005097184A2
(en)
|
2004-03-26 |
2005-10-20 |
Human Genome Sciences, Inc. |
Antibodies against nogo receptor
|
ATE540696T1
(de)
|
2004-04-08 |
2012-01-15 |
David B Agus |
Erbb2-antagonisten für die tumorschmerztherapie
|
ES2395094T3
(es)
|
2004-06-24 |
2013-02-08 |
Biogen Idec Ma Inc. |
Tratamiento de afecciones que implican la desmielinización
|
US20060009288A1
(en)
|
2004-07-07 |
2006-01-12 |
Devos John A |
Conveying information to an interrogator using resonant and parasitic radio frequency circuits
|
JP5060293B2
(ja)
|
2004-08-03 |
2012-10-31 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
神経機能におけるtaj
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
AR054260A1
(es)
|
2005-04-26 |
2007-06-13 |
Rinat Neuroscience Corp |
Metodos de tratamiento de enfermedades de la neurona motora inferior y composiciones utilizadas en los mismos
|
CA2606479A1
(en)
|
2005-04-29 |
2006-11-09 |
Wyeth |
Nogo receptor functional motifs and peptide mimetics related thereto and methods of using the same
|
WO2006136006A1
(en)
|
2005-05-16 |
2006-12-28 |
Mcgill University |
Lgi, lingo and p75ntr family members: novel modulators of neuronal growth
|
CN101273064A
(zh)
|
2005-06-06 |
2008-09-24 |
惠氏公司 |
抗-TrkB单克隆抗体及其用途
|
ES2569881T3
(es)
|
2005-06-08 |
2016-05-12 |
The University Of North Carolina At Chapel Hill |
Procedimientos para facilitar la supervivencia de células neuronales usando miméticos de neurotrofina BDNF peptídicos y no peptídicos
|
JP2008543790A
(ja)
|
2005-06-16 |
2008-12-04 |
ユニバーシティー・テクノロジーズ・インターナショナル・インコーポレイテッド |
短腸症候群の治療
|
PL1904104T3
(pl)
|
2005-07-08 |
2014-02-28 |
Biogen Ma Inc |
Przeciwciała SP35 i ich zastosowania
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
JP2009513666A
(ja)
|
2005-10-27 |
2009-04-02 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
希乏突起神経膠細胞−ミエリン糖タンパク質組成物およびその使用方法
|
MX2008005764A
(es)
|
2005-11-04 |
2008-11-18 |
Biogen Idec Inc |
Metodos para promover el crecimiento de neuritas y la supervivencia en neuronas dopaminergicas.
|
EP2543384A3
(en)
|
2005-12-02 |
2013-04-10 |
Biogen Idec MA Inc. |
Treatment of conditions involving demyelination
|
US20070186296A1
(en)
|
2006-02-02 |
2007-08-09 |
Wyeth |
Cloning, characterization, and application of tnfrsf19 in neurological disorders
|
CN101405297A
(zh)
|
2006-02-03 |
2009-04-08 |
惠氏公司 |
Lingo-1结构
|
WO2007098283A2
(en)
|
2006-02-27 |
2007-08-30 |
Biogen Idec Ma Inc. |
Use of antagonists of maif receptor complex molecules and neurotrophic factors for treatment of neurological diseases and disorders
|
US8642040B2
(en)
|
2006-07-24 |
2014-02-04 |
Biogen Idec Ma Inc. |
Methods for promoting myelination, neuronal survival and oligodendrocyte differentiation via administration of Sp35 or TrkA antagonists
|
CN101553506B
(zh)
|
2006-11-17 |
2013-08-07 |
诺瓦提斯公司 |
Lingo结合分子及其制药用途
|
US8128926B2
(en)
|
2007-01-09 |
2012-03-06 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
MX2009007375A
(es)
|
2007-01-09 |
2009-07-21 |
Biogen Idec Inc |
Anticuerpos sp35 y usos de los mismos.
|
CN101980603A
(zh)
|
2007-10-11 |
2011-02-23 |
比奥根艾迪克Ma公司 |
LINGO-1和TrkB拮抗剂的用途
|
JP5754046B2
(ja)
|
2007-11-08 |
2015-07-22 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
脱髄を伴う状態の治療におけるlingo−4アンタゴニストの使用
|
DK2307042T3
(da)
|
2008-06-25 |
2014-05-12 |
Lundbeck & Co As H |
Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte
|
NZ590668A
(en)
|
2008-07-02 |
2012-12-21 |
Emergent Product Dev Seattle |
TNF-alpha ANTAGONIST MULTI-TARGET BINDING PROTEINS
|
US8058406B2
(en)
|
2008-07-09 |
2011-11-15 |
Biogen Idec Ma Inc. |
Composition comprising antibodies to LINGO or fragments thereof
|
CN105039523A
(zh)
|
2008-11-17 |
2015-11-11 |
威拉赛特公司 |
用于疾病诊断的分子表达谱的方法和组合物
|
FR2958293B1
(fr)
|
2010-04-01 |
2014-09-26 |
Centre Nat Rech Scient |
Outils pour l'identification de ligands de lingo-1,lingo-2, lingo-3 et lingo-4, et utilisations
|
MX2014013950A
(es)
|
2012-05-14 |
2015-02-17 |
Biogen Idec Inc |
Antagonistas de proteina que interactua con el receptor nogo 2 que contiene repeticion rica en leucina y dominio de inmunoglobulina (lingo-2) para el tratamiento de afecciones que involucran neuronas motoras.
|