FI111258B - 1,3-diokso-6-(3-metyyliaminopropyyli)-1,2,3,6-tetrahydro-4-(3-tienyyli)pyrrolo[3,4-c]karbatsoli ja sen suolat sekä näiden käyttö ja farmaseuttinen koostumus - Google Patents

1,3-diokso-6-(3-metyyliaminopropyyli)-1,2,3,6-tetrahydro-4-(3-tienyyli)pyrrolo[3,4-c]karbatsoli ja sen suolat sekä näiden käyttö ja farmaseuttinen koostumus Download PDF

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Publication number
FI111258B
FI111258B FI953710A FI953710A FI111258B FI 111258 B FI111258 B FI 111258B FI 953710 A FI953710 A FI 953710A FI 953710 A FI953710 A FI 953710A FI 111258 B FI111258 B FI 111258B
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FI
Finland
Prior art keywords
formula
compound
thienyl
acid
pharmaceutical composition
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Application number
FI953710A
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English (en)
Finnish (fi)
Swedish (sv)
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FI953710A0 (fi
FI953710A (fi
Inventor
Chris Allen Broka
Original Assignee
Hoffmann La Roche
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Publication of FI953710A0 publication Critical patent/FI953710A0/fi
Publication of FI953710A publication Critical patent/FI953710A/fi
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Publication of FI111258B publication Critical patent/FI111258B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
FI953710A 1994-08-04 1995-08-03 1,3-diokso-6-(3-metyyliaminopropyyli)-1,2,3,6-tetrahydro-4-(3-tienyyli)pyrrolo[3,4-c]karbatsoli ja sen suolat sekä näiden käyttö ja farmaseuttinen koostumus FI111258B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04
US28604394 1994-08-04

Publications (3)

Publication Number Publication Date
FI953710A0 FI953710A0 (fi) 1995-08-03
FI953710A FI953710A (fi) 1996-02-05
FI111258B true FI111258B (fi) 2003-06-30

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953710A FI111258B (fi) 1994-08-04 1995-08-03 1,3-diokso-6-(3-metyyliaminopropyyli)-1,2,3,6-tetrahydro-4-(3-tienyyli)pyrrolo[3,4-c]karbatsoli ja sen suolat sekä näiden käyttö ja farmaseuttinen koostumus

Country Status (30)

Country Link
US (1) US5721267A (no)
EP (1) EP0695755B1 (no)
JP (1) JP2672290B2 (no)
KR (1) KR100326790B1 (no)
CN (1) CN1051551C (no)
AT (1) ATE172463T1 (no)
AU (1) AU692563B2 (no)
BR (1) BR9503536A (no)
CA (1) CA2155148A1 (no)
CO (1) CO4410329A1 (no)
CZ (1) CZ288583B6 (no)
DE (1) DE69505470T2 (no)
DK (1) DK0695755T3 (no)
ES (1) ES2123873T3 (no)
FI (1) FI111258B (no)
HK (1) HK1012341A1 (no)
HU (1) HU225567B1 (no)
IL (1) IL114785A (no)
MA (1) MA23639A1 (no)
MY (1) MY117092A (no)
NO (1) NO304833B1 (no)
NZ (1) NZ272687A (no)
PE (1) PE34996A1 (no)
PL (1) PL180801B1 (no)
RU (1) RU2162089C2 (no)
SA (1) SA95160203B1 (no)
TR (1) TR199500954A1 (no)
TW (1) TW403652B (no)
UY (1) UY24010A1 (no)
ZA (1) ZA956327B (no)

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Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
JPWO2003051883A1 (ja) * 2001-12-18 2005-04-28 協和醗酵工業株式会社 インドール誘導体
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
EP1501831A1 (en) * 2002-04-26 2005-02-02 Warner-Lambert Company Llc Inhibitors of checkpoint kinases (wee1 and chk1)
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Ｅｇ５阻害剤
PL2441753T3 (pl) * 2009-06-10 2016-09-30 Związek tetracykliczny
AR083246A1 (es) 2010-08-20 2013-02-13 Chugai Pharmaceutical Co Ltd Composicion que comprende compuestos tetraciclicos
LT2902029T (lt) 2012-09-25 2018-10-25 Chugai Seiyaku Kabushiki Kaisha Ret inhibitorius
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
TWI720943B (zh) 2014-04-25 2021-03-11 日商中外製藥股份有限公司 以高用量含有４環性化合物的製劑
US9714229B2 (en) 2014-04-25 2017-07-25 Chugai Seiyaku Kabushiki Kaisha Crystal of tetracyclic compound
TWI718102B (zh) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 ４環性化合物的非晶質體
RU2740261C2 (ru) 2015-01-16 2021-01-12 Чугаи Сейяку Кабусики Кайся Комбинированное лекарственное средство
KR102635225B1 (ko) 2018-09-04 2024-02-07 추가이 세이야쿠 가부시키가이샤 4환성 화합물의 제조방법
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
CZ280738B6 (cs) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
GB2239013B (en) * 1989-11-01 1993-06-02 Toyama Chemical Co Ltd Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
JP3344586B2 (ja) * 1993-05-28 2002-11-11 セファロン，インコーポレイテッド インドロカルバゾール誘導体を含有する前立腺病理疾患の治療剤

Also Published As

Publication number Publication date
MY117092A (en) 2004-05-31
RU2162089C2 (ru) 2001-01-20
NO304833B1 (no) 1999-02-22
FI953710A0 (fi) 1995-08-03
JP2672290B2 (ja) 1997-11-05
SA95160203B1 (ar) 2005-07-31
BR9503536A (pt) 1996-06-04
JPH0859666A (ja) 1996-03-05
MA23639A1 (fr) 1996-04-01
ATE172463T1 (de) 1998-11-15
TW403652B (en) 2000-09-01
FI953710A (fi) 1996-02-05
UY24010A1 (es) 2000-12-29
CZ199795A3 (en) 1996-02-14
PE34996A1 (es) 1996-10-01
IL114785A (en) 1998-06-15
PL309874A1 (en) 1996-02-05
DK0695755T3 (da) 1999-06-28
DE69505470D1 (de) 1998-11-26
CN1051551C (zh) 2000-04-19
KR100326790B1 (ko) 2002-07-27
CN1123280A (zh) 1996-05-29
EP0695755B1 (en) 1998-10-21
HU9502270D0 (en) 1995-09-28
HK1012341A1 (en) 1999-07-30
ES2123873T3 (es) 1999-01-16
DE69505470T2 (de) 1999-05-12
CA2155148A1 (en) 1996-02-05
TR199500954A1 (tr) 1996-10-21
CO4410329A1 (es) 1997-01-09
CZ288583B6 (cs) 2001-07-11
HUT73437A (en) 1996-07-29
NZ272687A (en) 1997-04-24
US5721267A (en) 1998-02-24
PL180801B1 (pl) 2001-04-30
KR960007592A (ko) 1996-03-22
NO953052D0 (no) 1995-08-03
HU225567B1 (en) 2007-03-28
EP0695755A1 (en) 1996-02-07
ZA956327B (en) 1996-02-04
AU692563B2 (en) 1998-06-11
AU2722095A (en) 1996-02-15
IL114785A0 (en) 1995-11-27
NO953052L (no) 1996-02-05

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