DE69505470D1 - Pyrrolocarbazol - Google Patents

Pyrrolocarbazol

Info

Publication number
DE69505470D1
DE69505470D1 DE69505470T DE69505470T DE69505470D1 DE 69505470 D1 DE69505470 D1 DE 69505470D1 DE 69505470 T DE69505470 T DE 69505470T DE 69505470 T DE69505470 T DE 69505470T DE 69505470 D1 DE69505470 D1 DE 69505470D1
Authority
DE
Germany
Prior art keywords
lower alkyl
pyrrolocarbazole
hydrogen
heteroaryl
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69505470T
Other languages
English (en)
Other versions
DE69505470T2 (de
Inventor
Chris Allen Broka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE69505470D1 publication Critical patent/DE69505470D1/de
Application granted granted Critical
Publication of DE69505470T2 publication Critical patent/DE69505470T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
DE69505470T 1994-08-04 1995-07-21 Pyrrolocarbazol Expired - Fee Related DE69505470T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04

Publications (2)

Publication Number Publication Date
DE69505470D1 true DE69505470D1 (de) 1998-11-26
DE69505470T2 DE69505470T2 (de) 1999-05-12

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69505470T Expired - Fee Related DE69505470T2 (de) 1994-08-04 1995-07-21 Pyrrolocarbazol

Country Status (30)

Country Link
US (1) US5721267A (de)
EP (1) EP0695755B1 (de)
JP (1) JP2672290B2 (de)
KR (1) KR100326790B1 (de)
CN (1) CN1051551C (de)
AT (1) ATE172463T1 (de)
AU (1) AU692563B2 (de)
BR (1) BR9503536A (de)
CA (1) CA2155148A1 (de)
CO (1) CO4410329A1 (de)
CZ (1) CZ288583B6 (de)
DE (1) DE69505470T2 (de)
DK (1) DK0695755T3 (de)
ES (1) ES2123873T3 (de)
FI (1) FI111258B (de)
HK (1) HK1012341A1 (de)
HU (1) HU225567B1 (de)
IL (1) IL114785A (de)
MA (1) MA23639A1 (de)
MY (1) MY117092A (de)
NO (1) NO304833B1 (de)
NZ (1) NZ272687A (de)
PE (1) PE34996A1 (de)
PL (1) PL180801B1 (de)
RU (1) RU2162089C2 (de)
SA (1) SA95160203B1 (de)
TR (1) TR199500954A1 (de)
TW (1) TW403652B (de)
UY (1) UY24010A1 (de)
ZA (1) ZA956327B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
JPWO2003051883A1 (ja) * 2001-12-18 2005-04-28 協和醗酵工業株式会社 インドール誘導体
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
EP1501831A1 (de) * 2002-04-26 2005-02-02 Warner-Lambert Company Llc Kontrollpunktkinase (wee1 und chk1) inhibitoren
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Eg5阻害剤
PL2441753T3 (pl) * 2009-06-10 2016-09-30 Związek tetracykliczny
AR083246A1 (es) 2010-08-20 2013-02-13 Chugai Pharmaceutical Co Ltd Composicion que comprende compuestos tetraciclicos
LT2902029T (lt) 2012-09-25 2018-10-25 Chugai Seiyaku Kabushiki Kaisha Ret inhibitorius
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
TWI720943B (zh) 2014-04-25 2021-03-11 日商中外製藥股份有限公司 以高用量含有4環性化合物的製劑
US9714229B2 (en) 2014-04-25 2017-07-25 Chugai Seiyaku Kabushiki Kaisha Crystal of tetracyclic compound
TWI718102B (zh) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 4環性化合物的非晶質體
RU2740261C2 (ru) 2015-01-16 2021-01-12 Чугаи Сейяку Кабусики Кайся Комбинированное лекарственное средство
KR102635225B1 (ko) 2018-09-04 2024-02-07 추가이 세이야쿠 가부시키가이샤 4환성 화합물의 제조방법
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
CZ280738B6 (cs) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
GB2239013B (en) * 1989-11-01 1993-06-02 Toyama Chemical Co Ltd Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
JP3344586B2 (ja) * 1993-05-28 2002-11-11 セファロン,インコーポレイテッド インドロカルバゾール誘導体を含有する前立腺病理疾患の治療剤

Also Published As

Publication number Publication date
MY117092A (en) 2004-05-31
RU2162089C2 (ru) 2001-01-20
NO304833B1 (no) 1999-02-22
FI953710A0 (fi) 1995-08-03
JP2672290B2 (ja) 1997-11-05
SA95160203B1 (ar) 2005-07-31
BR9503536A (pt) 1996-06-04
JPH0859666A (ja) 1996-03-05
MA23639A1 (fr) 1996-04-01
ATE172463T1 (de) 1998-11-15
TW403652B (en) 2000-09-01
FI953710A (fi) 1996-02-05
UY24010A1 (es) 2000-12-29
CZ199795A3 (en) 1996-02-14
PE34996A1 (es) 1996-10-01
IL114785A (en) 1998-06-15
PL309874A1 (en) 1996-02-05
DK0695755T3 (da) 1999-06-28
CN1051551C (zh) 2000-04-19
KR100326790B1 (ko) 2002-07-27
CN1123280A (zh) 1996-05-29
EP0695755B1 (de) 1998-10-21
HU9502270D0 (en) 1995-09-28
HK1012341A1 (en) 1999-07-30
ES2123873T3 (es) 1999-01-16
DE69505470T2 (de) 1999-05-12
CA2155148A1 (en) 1996-02-05
TR199500954A1 (tr) 1996-10-21
CO4410329A1 (es) 1997-01-09
CZ288583B6 (cs) 2001-07-11
HUT73437A (en) 1996-07-29
NZ272687A (en) 1997-04-24
US5721267A (en) 1998-02-24
PL180801B1 (pl) 2001-04-30
KR960007592A (ko) 1996-03-22
NO953052D0 (no) 1995-08-03
HU225567B1 (en) 2007-03-28
EP0695755A1 (de) 1996-02-07
ZA956327B (en) 1996-02-04
FI111258B (fi) 2003-06-30
AU692563B2 (en) 1998-06-11
AU2722095A (en) 1996-02-15
IL114785A0 (en) 1995-11-27
NO953052L (no) 1996-02-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee