JPS6051189B2
(ja)
*
|
1980-07-21 |
1985-11-12 |
株式会社日立製作所 |
磁気バブル駆動回路
|
JPS60226873A
(ja)
*
|
1984-03-28 |
1985-11-12 |
Sankyo Co Ltd |
1,3−ベンゾオキサチオ−ル誘導体及びその製法
|
CN1003445B
(zh)
*
|
1984-10-03 |
1989-03-01 |
武田药品工业株式会社 |
噻唑烷二酮衍生物,其制备方法和用途
|
DK173350B1
(da)
*
|
1985-02-26 |
2000-08-07 |
Sankyo Co |
Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
|
JPH0653738B2
(ja)
*
|
1985-02-26 |
1994-07-20 |
三共株式会社 |
チアゾリジン誘導体
|
US4738972A
(en)
*
|
1985-05-21 |
1988-04-19 |
Pfizer Inc. |
Hypoglycemic thiazolidinediones
|
US4703052A
(en)
*
|
1985-05-21 |
1987-10-27 |
Pfizer Inc. |
Hypoglycemic thiazolidinediones
|
JPH06779B2
(ja)
*
|
1985-06-10 |
1994-01-05 |
武田薬品工業株式会社 |
チアゾリジオン誘導体およびそれを含んでなる医薬組成物
|
JPS62234085A
(ja)
*
|
1985-12-18 |
1987-10-14 |
Sankyo Co Ltd |
チアゾリジン誘導体を有効成分とする糖尿病性合併症治療剤
|
JP2574845B2
(ja)
*
|
1987-02-04 |
1997-01-22 |
三共株式会社 |
チアゾリジン化合物
|
US4873255A
(en)
*
|
1987-02-04 |
1989-10-10 |
Sankyo Company Limited |
Thiazolidinone derivatives, their preparation and their use
|
US4798835A
(en)
*
|
1987-12-02 |
1989-01-17 |
Pfizer Inc. |
dl-5-[(2-benzyl-3,4-dihydro-2H-benzopyran-6-yl)methyl]thiazolidine-2,4-dione as an anti-atherosclerosis agent
|
US4791125A
(en)
*
|
1987-12-02 |
1988-12-13 |
Pfizer Inc. |
Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
|
US5132310A
(en)
*
|
1988-08-09 |
1992-07-21 |
Hoffmann-La Roche Inc. |
Pharmacologically active chromanes
|
US5260294A
(en)
*
|
1988-08-09 |
1993-11-09 |
Hoffman-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
US5015661A
(en)
*
|
1988-08-09 |
1991-05-14 |
Hoffmann-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
GB8919417D0
(en)
|
1989-08-25 |
1989-10-11 |
Beecham Group Plc |
Novel compounds
|
US5053420A
(en)
*
|
1989-10-13 |
1991-10-01 |
Pershadsingh Harrihar A |
Thiazolidine derivatives for the treatment of hypertension
|
JP2826379B2
(ja)
*
|
1990-01-22 |
1998-11-18 |
三共株式会社 |
チアゾリジン誘導体を有効成分とする肥満性高血圧症治療剤
|
US5143930A
(en)
*
|
1990-02-07 |
1992-09-01 |
Sankyo Company, Limited |
Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
|
ES2059121T5
(es)
*
|
1990-02-09 |
2000-12-01 |
Upjohn Co |
Uso de agentes sensibilizantes de la insulina para tratar la hipertension.
|
US5356913A
(en)
*
|
1990-02-09 |
1994-10-18 |
The Upjohn Company |
Use of insulin sensitizing agents to treat hypertension
|
DE69132713D1
(de)
*
|
1990-04-27 |
2001-10-11 |
Sankyo Co |
Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren
|
GB9023584D0
(en)
*
|
1990-10-30 |
1990-12-12 |
Beecham Group Plc |
Novel compounds
|
CA2082003A1
(en)
*
|
1991-11-20 |
1993-05-21 |
David Laffan |
Process for the preparation of substituted pentaalkylchromenes
|
JP3722293B2
(ja)
*
|
1991-12-18 |
2005-11-30 |
ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー |
新規な薬学的固体分散物
|
NO302471B1
(no)
*
|
1991-12-26 |
1998-03-09 |
Sankyo Co |
Tiazolidinforbindelser og farmasöytisk preparat
|
NO302519B1
(no)
*
|
1991-12-26 |
1998-03-16 |
Sankyo Co |
Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
|
CA2089013A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2, 5, 7, 8- tetraalkyl-2-(4-aminophenoxymethyl) chromans
|
CA2089012A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2,5,7,8-tetra- alkyl-2-(4-aminophenoxymethyl) chromans
|
ATE185564T1
(de)
|
1992-08-31 |
1999-10-15 |
Sankyo Co |
Oxazolidin-derivate mit antidiabetika und anti- fettleibigkeit-eigenschaften, ihre herstellung und therapeutische verwendung
|
JPH0631079U
(ja)
*
|
1992-09-22 |
1994-04-22 |
沖電線株式会社 |
シート付き小型smtコネクタ
|
US5594016A
(en)
*
|
1992-12-28 |
1997-01-14 |
Mitsubishi Chemical Corporation |
Naphthalene derivatives
|
AU6114794A
(en)
*
|
1993-02-24 |
1994-09-14 |
Sankyo Company Limited |
Arteriosclerosis remedy
|
USRE39384E1
(en)
|
1993-09-01 |
2006-11-07 |
Smithkline Beecham P.L.C. |
Substituted thiazolidinedione derivatives
|
US5457109A
(en)
*
|
1993-09-15 |
1995-10-10 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
US5874454A
(en)
*
|
1993-09-15 |
1999-02-23 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
CN1103590C
(zh)
*
|
1993-09-15 |
2003-03-26 |
三共株式会社 |
使用噻唑烷二酮防止或延缓非胰岛素依赖性糖尿病(niddm)的发作
|
AU749416B2
(en)
*
|
1993-09-15 |
2002-06-27 |
Daiichi Sankyo Company, Limited |
Use of thiazolidinediones to prevent or delay onset of NIDDM
|
US6046222A
(en)
*
|
1993-09-15 |
2000-04-04 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
ATE179709T1
(de)
|
1993-12-27 |
1999-05-15 |
Japan Tobacco Inc |
Isoxazolidindionderivate und deren verwendung
|
IL113313A
(en)
*
|
1994-04-11 |
1999-09-22 |
Sankyo Co |
Heterocyclic compounds and pharmaceutical compositions containing the same
|
US5594015A
(en)
*
|
1994-06-22 |
1997-01-14 |
Regents Of The University Of California |
Thiazolidine derivatives for the treatment of psoriasis
|
CA2159938A1
(en)
*
|
1994-10-07 |
1996-04-08 |
Hiroaki Yanagisawa |
Oxime derivatives, their preparation and their therapeutic use
|
US5708012A
(en)
*
|
1995-04-28 |
1998-01-13 |
Sankyo Company, Limited |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus
|
CZ293016B6
(cs)
*
|
1995-06-01 |
2004-01-14 |
Sankyo Company Limited |
Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem
|
HUP9601808A3
(en)
*
|
1995-07-03 |
2000-06-28 |
Sankyo Co |
Treatment of arteriosclerosis and xanthoma
|
EP0851757A2
(en)
*
|
1995-08-10 |
1998-07-08 |
Warner-Lambert Company |
A method of reducing the amount of exogenous insulin administered to a patient having noninsulin-dependent diabetes mellitus
|
WO1997018811A1
(en)
*
|
1995-11-17 |
1997-05-29 |
Warner-Lambert Company |
A method of treating myotonic dystrophy
|
EP0783888A1
(en)
|
1995-12-26 |
1997-07-16 |
Sankyo Company Limited |
Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
|
WO1997027191A1
(en)
*
|
1996-06-19 |
1997-07-31 |
Dr. Reddy's Research Foundation |
Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation
|
IN182496B
(es)
*
|
1996-02-20 |
1999-04-17 |
Reddy Research Foundation |
|
IL120443A
(en)
*
|
1996-03-18 |
2000-07-16 |
Sankyo Co |
Use of an insulin sensitizer for the manufacture of a medicament for the treatment or prophylaxis of pancreatitis
|
WO1997037970A1
(fr)
*
|
1996-04-04 |
1997-10-16 |
Sankyo Company, Limited |
Derives d'acide phenylalkylcarboxylique
|
DE69625795T2
(de)
*
|
1996-04-09 |
2003-08-14 |
Dr. Reddy's Laboratories Ltd., Hyderabad |
Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven Eigenschaften, Verfahren zu deren Herstellung und pharmazeutischen Zusammenstellungen, die sie enthalten
|
US5919782A
(en)
*
|
1996-05-06 |
1999-07-06 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
ZA973850B
(en)
*
|
1996-05-06 |
1997-12-02 |
Reddy Research Foundation |
Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
|
ZA973848B
(en)
*
|
1996-05-06 |
1997-12-02 |
Reddy Research Foundation |
Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
|
US5801173A
(en)
*
|
1996-05-06 |
1998-09-01 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
WO1997043283A1
(de)
*
|
1996-05-16 |
1997-11-20 |
Boehringer Mannheim Gmbh |
Neues verfahren zur herstellung von troglitazone
|
DE19619819A1
(de)
*
|
1996-05-16 |
1997-11-20 |
Boehringer Mannheim Gmbh |
Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltenden Arzneimittel
|
CA2257284C
(en)
*
|
1996-05-31 |
2005-10-04 |
Sankyo Company Limited |
Remedy for autoimmune diseases
|
GB9611947D0
(en)
*
|
1996-06-07 |
1996-08-07 |
Glaxo Group Ltd |
Medicaments
|
US6372750B2
(en)
|
1996-07-01 |
2002-04-16 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
|
US5885997A
(en)
*
|
1996-07-01 |
1999-03-23 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
KR100579765B1
(ko)
|
1996-07-01 |
2006-12-28 |
닥터 레디스 레보러터리즈 리미티드 |
신규헤테로고리형화합물의제조방법,이를함유하는약제조성물및당뇨병및이와관련된질병의치료에있어서그의용도
|
USRE39266E1
(en)
*
|
1996-07-01 |
2006-09-05 |
Dr. Reddy's Laboratories, Limited |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
US6114526A
(en)
|
1996-07-01 |
2000-09-05 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
EP0921798A1
(en)
*
|
1996-07-12 |
1999-06-16 |
Smithkline Beecham Plc |
Novel treatment of leptine resistance
|
IL128771A0
(en)
*
|
1996-09-12 |
2000-01-31 |
Sankyo Co |
An agent for enhancing the activity of glutathione reductase containing troglitazone and use thereof
|
ATE399545T1
(de)
*
|
1996-11-08 |
2008-07-15 |
Nippon Chemiphar Co |
Mittel zur verringerung der eigeweidefette
|
JP2001514663A
(ja)
*
|
1997-03-12 |
2001-09-11 |
エスモンド,ロバート ダブリュー. |
アルツハイマー病を処置または予防するための方法
|
US6011036A
(en)
*
|
1997-04-15 |
2000-01-04 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them
|
US6011031A
(en)
*
|
1997-05-30 |
2000-01-04 |
Dr. Reddy's Research Foundation |
Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
|
SE9702305D0
(sv)
|
1997-06-17 |
1997-06-17 |
Astra Ab |
New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
|
CZ299310B6
(cs)
|
1997-06-18 |
2008-06-18 |
Smithkline Beecham Plc |
Lécivo pro lécbu diabetes mellitus a stavu spojených s diabetes mellitus
|
JP2002504137A
(ja)
*
|
1997-06-18 |
2002-02-05 |
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー |
チアゾリジンジオンおよびメトホルミンを用いる糖尿病の治療
|
GB9715295D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
GB9715306D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
US6171856B1
(en)
|
1997-07-30 |
2001-01-09 |
Board Of Regents, The University Of Texas System |
Methods and compositions relating to no-mediated cytotoxicity
|
FR2766820B1
(fr)
*
|
1997-07-31 |
1999-10-22 |
Rhodia Chimie Sa |
Procede de preparation de 2h-1-benzopyranes et intermediaires de synthese utiles dans la mise en oeuvre du procede
|
HUP0003881A3
(en)
|
1997-10-02 |
2001-04-28 |
Sankyo Co |
Amidocarboxylic acid derivatives
|
EP0916665A1
(de)
*
|
1997-11-11 |
1999-05-19 |
Lonza A.G. |
Verfahren zur Herstellung von Chromanderivaten
|
KR100567183B1
(ko)
*
|
1997-11-14 |
2006-06-13 |
론자 아게 |
포르밀이미다졸의제조방법
|
HUP9902721A2
(hu)
*
|
1997-11-25 |
1999-12-28 |
The Procter & Gamble Co. |
Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
|
AU1507799A
(en)
*
|
1997-12-16 |
1999-07-05 |
Sankyo Company Limited |
Leukemia remedy
|
US20040058873A1
(en)
*
|
1998-03-12 |
2004-03-25 |
Esmond Robert W. |
Method for treating or preventing Alzheimer's disease
|
JP4523153B2
(ja)
|
1998-03-19 |
2010-08-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
易溶性薬物の二層性放出制御送達システムおよび方法
|
WO2000007582A2
(en)
*
|
1998-08-06 |
2000-02-17 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives for the treatment or prevention of cataracts
|
AU5514199A
(en)
*
|
1998-08-19 |
2000-03-14 |
Sankyo Company Limited |
Process for the preparation of 2-(aryloxymethyl)-2,5,7,8-tetramethylchroman-6-ols
|
WO2000015229A1
(en)
|
1998-09-17 |
2000-03-23 |
Bristol-Myers Squibb Company |
METHOD FOR TREATING DIABETES EMPLOYING AN aP2 INHIBITOR AND COMBINATION
|
US6028088A
(en)
*
|
1998-10-30 |
2000-02-22 |
The University Of Mississippi |
Flavonoid derivatives
|
GB9824893D0
(en)
*
|
1998-11-12 |
1999-01-06 |
Smithkline Beckman Corp |
Novel method of treatment
|
AR023700A1
(es)
|
1998-11-12 |
2002-09-04 |
Smithkline Beecham Plc |
Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
|
EA007610B1
(ru)
|
1998-11-12 |
2006-12-29 |
Смитклайн Бичам Плс |
Таблетка с энтеропокрытием, обеспечивающая отсроченное высвобождение
|
CA2350599A1
(en)
*
|
1998-11-20 |
2000-06-02 |
Genentech, Inc. |
Method of inhibiting angiogenesis
|
US6191154B1
(en)
|
1998-11-27 |
2001-02-20 |
Case Western Reserve University |
Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
|
US5968960A
(en)
*
|
1999-01-14 |
1999-10-19 |
The Regents Of The University Of California |
Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism
|
US6204288B1
(en)
|
1999-03-08 |
2001-03-20 |
The University Of Mississippi |
1,2-dithiolane derivatives
|
US6127394A
(en)
*
|
1999-03-08 |
2000-10-03 |
The University Of Mississippi |
1,2-Dithiolane derivatives
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
US7041691B1
(en)
*
|
1999-06-30 |
2006-05-09 |
Amgen Inc. |
Compounds for the modulation of PPARγ activity
|
JP2001072592A
(ja)
|
1999-07-01 |
2001-03-21 |
Kyowa Hakko Kogyo Co Ltd |
テロメラーゼ阻害剤
|
US6878749B2
(en)
|
1999-09-17 |
2005-04-12 |
Novartis Ag |
Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
|
CO5200844A1
(es)
|
1999-09-17 |
2002-09-27 |
Novartis Ag |
Una combinacion que comprende nateglinida y cuando por menos otro compuesto antidiabetico usada para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con dibetes
|
US6559188B1
(en)
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
US6586438B2
(en)
|
1999-11-03 |
2003-07-01 |
Bristol-Myers Squibb Co. |
Antidiabetic formulation and method
|
HUP0203431A3
(en)
|
1999-12-03 |
2003-11-28 |
Kyoto Pharma Ind |
Novel heterocyclic compounds and salts thereof and pharmaceutical compositions containing and use of the same
|
DK1741446T3
(da)
|
2000-01-21 |
2008-06-02 |
Novartis Pharma Ag |
Kombinationer indeholdende dipeptidylpeptidase-IV-inhibitorer og antidiabetiske midler
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
US6958355B2
(en)
*
|
2000-04-24 |
2005-10-25 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
US6680387B2
(en)
*
|
2000-04-24 |
2004-01-20 |
Aryx Therapeutics |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
AU6118001A
(en)
*
|
2000-05-03 |
2001-11-12 |
Tularik Inc |
Combination therapeutic compositions and methods of use
|
GB0014969D0
(en)
|
2000-06-19 |
2000-08-09 |
Smithkline Beecham Plc |
Novel method of treatment
|
US20030171399A1
(en)
*
|
2000-06-28 |
2003-09-11 |
Tularik Inc. |
Quinolinyl and benzothiazolyl modulators
|
WO2002011716A2
(en)
|
2000-08-07 |
2002-02-14 |
Ranbaxy Signature Llc |
Liquid formulation of metformin
|
WO2002024689A1
(en)
*
|
2000-09-21 |
2002-03-28 |
Aryx Therapeutics |
Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis
|
FR2816840B1
(fr)
*
|
2000-11-17 |
2004-04-09 |
Flamel Tech Sa |
Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
|
US6452014B1
(en)
|
2000-12-22 |
2002-09-17 |
Geron Corporation |
Telomerase inhibitors and methods of their use
|
DE60209343T2
(de)
|
2001-04-11 |
2006-10-26 |
Bristol-Myers Squibb Co. |
Aminosäurekomplexe von c-arylglycosiden zur behandlung von diabetes und verfahren
|
US20060047000A1
(en)
*
|
2001-04-24 |
2006-03-02 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
CA2448634A1
(en)
*
|
2001-05-29 |
2002-12-05 |
Kyoto Pharmaceutical Industries, Ltd. |
Novel heterocyclic compound and medicinal use thereof
|
NZ530313A
(en)
*
|
2001-05-29 |
2005-06-24 |
Kyoto Pharma Ind |
Heterocyclic derivatives and medicinal use thereof
|
JP4152641B2
(ja)
*
|
2001-08-07 |
2008-09-17 |
クラシエ製薬株式会社 |
チアゾリジン誘導体の副作用軽減剤
|
US8101209B2
(en)
*
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
FR2830447B1
(fr)
*
|
2001-10-09 |
2004-04-16 |
Flamel Tech Sa |
Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
US6984645B2
(en)
*
|
2001-11-16 |
2006-01-10 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
US7015345B2
(en)
*
|
2002-02-21 |
2006-03-21 |
Asahi Kasei Pharma Corporation |
Propionic acid derivatives
|
CA2477088A1
(en)
|
2002-02-22 |
2003-10-02 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
IL164222A0
(en)
|
2002-04-09 |
2005-12-18 |
Flamel Tech Sa |
Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s)
|
DE60323474D1
(de)
*
|
2002-04-09 |
2008-10-23 |
Flamel Tech Sa |
Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
|
WO2003096548A2
(de)
*
|
2002-05-14 |
2003-11-20 |
Siemens Aktiengesellschaft |
Verfahren zum erzeugen eines sendesignals
|
US8268352B2
(en)
*
|
2002-08-05 |
2012-09-18 |
Torrent Pharmaceuticals Limited |
Modified release composition for highly soluble drugs
|
US8216609B2
(en)
*
|
2002-08-05 |
2012-07-10 |
Torrent Pharmaceuticals Limited |
Modified release composition of highly soluble drugs
|
WO2004066929A2
(en)
*
|
2003-01-24 |
2004-08-12 |
Bristol-Myers Squibb Company |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
WO2004094595A2
(en)
*
|
2003-04-17 |
2004-11-04 |
Alnylam Pharmaceuticals Inc. |
MODIFIED iRNA AGENTS
|
US8017762B2
(en)
*
|
2003-04-17 |
2011-09-13 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
US7851615B2
(en)
*
|
2003-04-17 |
2010-12-14 |
Alnylam Pharmaceuticals, Inc. |
Lipophilic conjugated iRNA agents
|
US7723509B2
(en)
|
2003-04-17 |
2010-05-25 |
Alnylam Pharmaceuticals |
IRNA agents with biocleavable tethers
|
US8796436B2
(en)
|
2003-04-17 |
2014-08-05 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
US20050004179A1
(en)
*
|
2003-05-22 |
2005-01-06 |
Pedersen Ward A. |
Methods and materials for treating, detecting, and reducing the risk of developing Alzheimer's Disease
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
US7371759B2
(en)
*
|
2003-09-25 |
2008-05-13 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7223761B2
(en)
|
2003-10-03 |
2007-05-29 |
Amgen Inc. |
Salts and polymorphs of a potent antidiabetic compound
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
KR100918322B1
(ko)
*
|
2003-11-12 |
2009-09-22 |
페노믹스 코포레이션 |
헤테로시클릭 보론산 화합물
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7420059B2
(en)
*
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7786163B2
(en)
*
|
2004-07-12 |
2010-08-31 |
Forest Laboratories Holdings Limited (BM) |
Constrained cyano compounds
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
EP1857118A1
(en)
*
|
2004-12-13 |
2007-11-21 |
Daiichi Sankyo Company, Limited |
Medicinal composition for treating diabetes
|
US7317024B2
(en)
|
2005-01-13 |
2008-01-08 |
Bristol-Myers Squibb Co. |
Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
ATE421518T1
(de)
*
|
2005-02-10 |
2009-02-15 |
Bristol Myers Squibb Co |
Dihydrochinazolinone als 5ht-modulatoren
|
US20070269486A1
(en)
*
|
2005-03-14 |
2007-11-22 |
Conor Medsystems, Llc. |
Methods and Devices for Reducing Tissue Damage After Ischemic Injury
|
EP1858845A2
(en)
*
|
2005-03-18 |
2007-11-28 |
Orchid Chemicals and Pharmaceuticals Limited |
Novel tyrosine derivatives
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7888381B2
(en)
|
2005-06-14 |
2011-02-15 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
|
AU2006275694A1
(en)
*
|
2005-07-28 |
2007-02-08 |
Bristol-Myers Squibb Company |
Substituted tetrahydro-1H-pyrido(4,3,b)indoles as serotonin receptor agonists and antagonists
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
US20080064884A1
(en)
*
|
2006-05-10 |
2008-03-13 |
Astrazeneca Ab |
Novel Process 1
|
EP2089389A2
(en)
|
2006-11-01 |
2009-08-19 |
Bristol-Myers Squibb Company |
Heterocyclic compounds as modulators of glucocorticoid receptor, ap-1, and/or nf-kappa-b activity
|
US8198311B2
(en)
|
2006-11-01 |
2012-06-12 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US7968577B2
(en)
|
2006-11-01 |
2011-06-28 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
CN107501407B
(zh)
*
|
2007-03-30 |
2022-03-18 |
Ambrx公司 |
经修饰fgf-21多肽和其用途
|
CA2684059C
(en)
*
|
2007-04-11 |
2016-07-12 |
Omeros Corporation |
Use of a ppary agonist, alone or in combination, for the treatment or prophylaxis of addictions
|
US11241420B2
(en)
|
2007-04-11 |
2022-02-08 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
US20160331729A9
(en)
*
|
2007-04-11 |
2016-11-17 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
EP2527360B1
(en)
|
2007-06-04 |
2015-10-28 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
CN101910171A
(zh)
|
2007-11-01 |
2010-12-08 |
百时美施贵宝公司 |
可用作糖皮质激素受体AP-1和/或者NF-κB活性调节剂的非甾类化合物及其用途
|
AU2009256157B2
(en)
|
2008-06-04 |
2014-12-18 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
JP2011528375A
(ja)
|
2008-07-16 |
2011-11-17 |
シナジー ファーマシューティカルズ インコーポレイテッド |
胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
|
MX2011006890A
(es)
*
|
2008-12-23 |
2011-07-20 |
Pharmasset Inc |
Analogos de nucleosidos.
|
US8716262B2
(en)
*
|
2008-12-23 |
2014-05-06 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
KR20110104074A
(ko)
|
2008-12-23 |
2011-09-21 |
파마셋 인코포레이티드 |
퓨린 뉴클레오시드의 합성
|
JP6163289B2
(ja)
|
2009-03-11 |
2017-07-12 |
オメロス コーポレーション |
嗜癖の予防および治療のための組成物および方法
|
CA2787685A1
(en)
|
2010-01-22 |
2011-07-28 |
Dana-Farber Cancer Institute, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of metabolic disorders
|
CN104017020B
(zh)
|
2010-03-31 |
2017-04-12 |
吉利德制药有限责任公司 |
核苷氨基磷酸酯
|
RU2596787C2
(ru)
|
2010-07-09 |
2016-09-10 |
БиЭйчВи ФАРМА, ИНК. |
Комбинированная система доставки с немедленным/замедленным высвобождением для лекарственных средств с коротким периодом полувыведения, в том числе для ремоглифлозина
|
WO2012027331A1
(en)
|
2010-08-27 |
2012-03-01 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
US20120094959A1
(en)
|
2010-10-19 |
2012-04-19 |
Bonnie Blazer-Yost |
Treatment of cystic diseases
|
WO2014057522A1
(en)
|
2012-10-12 |
2014-04-17 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
WO2014068397A1
(en)
|
2012-11-05 |
2014-05-08 |
Commissariat A L'energie Atomique Et Aux Energies Atlternatives (Cea) |
Combination of an anti-cancer agent such as a tyrosinekinase inhibitor and a stat5 antagonist, preferably a thiazolidinedione, for eliminating hematologic cancer stem cells in vivo and for preventing hematologic cancer relapse
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
JP2016514670A
(ja)
|
2013-03-15 |
2016-05-23 |
シナジー ファーマシューティカルズ インコーポレイテッド |
他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
|
US10441560B2
(en)
|
2013-03-15 |
2019-10-15 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
WO2014142364A2
(en)
|
2013-03-15 |
2014-09-18 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
EP4424697A2
(en)
|
2013-06-05 |
2024-09-04 |
Bausch Health Ireland Limited |
Ultra-pure agonists of guanylate cyclase c, method of making and using same
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
AU2014331812B2
(en)
|
2013-10-09 |
2019-01-17 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines
|
AU2015335603B2
(en)
|
2014-10-24 |
2020-04-30 |
Bristol-Myers Squibb Company |
Modified FGF-21 polypeptides and uses thereof
|
WO2016071727A1
(en)
|
2014-11-04 |
2016-05-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
|
AU2019304032B2
(en)
|
2018-07-19 |
2021-12-09 |
Astrazeneca Ab |
Methods of treating HFpEF employing dapagliflozin and compositions comprising the same
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
WO2023144722A1
(en)
|
2022-01-26 |
2023-08-03 |
Astrazeneca Ab |
Dapagliflozin for use in the treatment of prediabetes or reducing the risk of developing type 2 diabetes
|