DE69132713D1 - Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren - Google Patents

Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren

Info

Publication number
DE69132713D1
DE69132713D1 DE69132713T DE69132713T DE69132713D1 DE 69132713 D1 DE69132713 D1 DE 69132713D1 DE 69132713 T DE69132713 T DE 69132713T DE 69132713 T DE69132713 T DE 69132713T DE 69132713 D1 DE69132713 D1 DE 69132713D1
Authority
DE
Germany
Prior art keywords
preparation
lipid peroxide
hydrogen
compounds
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69132713T
Other languages
English (en)
Inventor
Toyonori Takebayashi
Takayuki Onodera
Kazuo Hasegawa
Takashi Fujita
Takao Yoshioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE69132713D1 publication Critical patent/DE69132713D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69132713T 1990-04-27 1991-04-29 Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren Expired - Lifetime DE69132713D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11356690 1990-04-27

Publications (1)

Publication Number Publication Date
DE69132713D1 true DE69132713D1 (de) 2001-10-11

Family

ID=14615508

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132713T Expired - Lifetime DE69132713D1 (de) 1990-04-27 1991-04-29 Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren

Country Status (4)

Country Link
US (1) US5387596A (de)
EP (2) EP0454501B1 (de)
AT (1) ATE205206T1 (de)
DE (1) DE69132713D1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL113313A (en) * 1994-04-11 1999-09-22 Sankyo Co Heterocyclic compounds and pharmaceutical compositions containing the same
IL118474A (en) * 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
US5747528A (en) * 1996-02-21 1998-05-05 Warner-Lambert Company Chroman derivatives as anti-oxidants
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5801173A (en) * 1996-05-06 1998-09-01 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5889032A (en) * 1996-05-06 1999-03-30 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
WO1997043283A1 (de) * 1996-05-16 1997-11-20 Boehringer Mannheim Gmbh Neues verfahren zur herstellung von troglitazone
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US5885997A (en) * 1996-07-01 1999-03-23 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
CA2258949C (en) * 1996-07-01 2008-05-06 Dr. Reddy's Research Foundation Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6632947B2 (en) 1997-02-18 2003-10-14 Smithkline Beecham Plc Process for the preparation of substituted thiazolidinedione
UY24886A1 (es) * 1997-02-18 2001-08-27 Smithkline Beecham Plc Tiazolidindiona
DE19711616A1 (de) * 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
IN187716B (de) * 1998-09-14 2002-06-15 Reddy Research Foundation
FR2786485A1 (fr) * 1998-11-27 2000-06-02 Rhodia Chimie Sa Procede de preparation de derives du 3-chromene, nouveaux derives du 3-chromene et utilisation de ces derives pour la preparation de thiazolidinones
FR2820742B1 (fr) * 2001-02-14 2005-03-11 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
US6992191B2 (en) * 2001-12-20 2006-01-31 Teva Pharmaceutical Industries, Ltd. Hydrogenation of precursors to thiazolidinedione antihyperglycemics
CN1319956C (zh) * 2003-09-12 2007-06-06 深圳市海粤门生物科技开发有限公司 一种噻唑烷二酮的衍生物及其药用制剂的制备方法和应用
WO2006069217A2 (en) * 2004-12-22 2006-06-29 The Ohio State Research Foundation Small molecule cyclin d1 ablative agents
WO2006069186A2 (en) 2004-12-22 2006-06-29 The Ohio State Research Foundation Small molecule bcl-xl/bcl-2 binding inhibitors
CA2716047A1 (en) 2008-02-22 2009-08-27 The Ohio State University Research Foundation Androgen receptor-ablative agents
CA2777406A1 (en) 2009-10-09 2011-04-14 The Ohio State University Research Foundation Thiazolidinedione energy restriction-mimetic agents
FR2986231B1 (fr) * 2012-01-26 2014-07-04 Centre Nat Rech Scient Derives de thiazolidinedione, leur preparation et leur utilisation dans le traitement des cancers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
US4703052A (en) * 1985-05-21 1987-10-27 Pfizer Inc. Hypoglycemic thiazolidinediones
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
US4873255A (en) * 1987-02-04 1989-10-10 Sankyo Company Limited Thiazolidinone derivatives, their preparation and their use
US4933355A (en) * 1988-04-14 1990-06-12 Sankyo Company Limited Thiazole derivatives, their preparation and their use in the treatment of diabetes complications

Also Published As

Publication number Publication date
EP0839812A1 (de) 1998-05-06
EP0454501B1 (de) 2001-09-05
US5387596A (en) 1995-02-07
EP0454501A2 (de) 1991-10-30
EP0454501A3 (en) 1992-04-08
ATE205206T1 (de) 2001-09-15

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Legal Events

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8332 No legal effect for de