JPS6051189B2
(ja)
*
|
1980-07-21 |
1985-11-12 |
株式会社日立製作所 |
磁気バブル駆動回路
|
JPS60226873A
(ja)
*
|
1984-03-28 |
1985-11-12 |
Sankyo Co Ltd |
1,3−ベンゾオキサチオ−ル誘導体及びその製法
|
CN1003445B
(zh)
*
|
1984-10-03 |
1989-03-01 |
武田药品工业株式会社 |
噻唑烷二酮衍生物,其制备方法和用途
|
JPH0653738B2
(ja)
*
|
1985-02-26 |
1994-07-20 |
三共株式会社 |
チアゾリジン誘導体
|
DK173350B1
(da)
|
1985-02-26 |
2000-08-07 |
Sankyo Co |
Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
|
US4738972A
(en)
*
|
1985-05-21 |
1988-04-19 |
Pfizer Inc. |
Hypoglycemic thiazolidinediones
|
US4703052A
(en)
*
|
1985-05-21 |
1987-10-27 |
Pfizer Inc. |
Hypoglycemic thiazolidinediones
|
JPH06779B2
(ja)
*
|
1985-06-10 |
1994-01-05 |
武田薬品工業株式会社 |
チアゾリジオン誘導体およびそれを含んでなる医薬組成物
|
JPS62234085A
(ja)
*
|
1985-12-18 |
1987-10-14 |
Sankyo Co Ltd |
チアゾリジン誘導体を有効成分とする糖尿病性合併症治療剤
|
JP2574845B2
(ja)
*
|
1987-02-04 |
1997-01-22 |
三共株式会社 |
チアゾリジン化合物
|
US4873255A
(en)
*
|
1987-02-04 |
1989-10-10 |
Sankyo Company Limited |
Thiazolidinone derivatives, their preparation and their use
|
US4791125A
(en)
*
|
1987-12-02 |
1988-12-13 |
Pfizer Inc. |
Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
|
US4798835A
(en)
*
|
1987-12-02 |
1989-01-17 |
Pfizer Inc. |
dl-5-[(2-benzyl-3,4-dihydro-2H-benzopyran-6-yl)methyl]thiazolidine-2,4-dione as an anti-atherosclerosis agent
|
US5260294A
(en)
*
|
1988-08-09 |
1993-11-09 |
Hoffman-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
US5015661A
(en)
*
|
1988-08-09 |
1991-05-14 |
Hoffmann-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
US5132310A
(en)
*
|
1988-08-09 |
1992-07-21 |
Hoffmann-La Roche Inc. |
Pharmacologically active chromanes
|
GB8919417D0
(en)
|
1989-08-25 |
1989-10-11 |
Beecham Group Plc |
Novel compounds
|
US5053420A
(en)
*
|
1989-10-13 |
1991-10-01 |
Pershadsingh Harrihar A |
Thiazolidine derivatives for the treatment of hypertension
|
JP2826379B2
(ja)
*
|
1990-01-22 |
1998-11-18 |
三共株式会社 |
チアゾリジン誘導体を有効成分とする肥満性高血圧症治療剤
|
US5143930A
(en)
*
|
1990-02-07 |
1992-09-01 |
Sankyo Company, Limited |
Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
|
US5356913A
(en)
*
|
1990-02-09 |
1994-10-18 |
The Upjohn Company |
Use of insulin sensitizing agents to treat hypertension
|
ATE93138T1
(de)
*
|
1990-02-09 |
1993-09-15 |
Upjohn Co |
Verwendung insulin-sensiblisierender wirkstoffe zur behandlung von hypertonie.
|
ATE205206T1
(de)
*
|
1990-04-27 |
2001-09-15 |
Sankyo Co |
Benzylidenthiazolidinderivate, ihre herstellung und ihre anwendung als lipidperoxid-inhibitoren
|
GB9023584D0
(en)
*
|
1990-10-30 |
1990-12-12 |
Beecham Group Plc |
Novel compounds
|
CA2082003A1
(en)
*
|
1991-11-20 |
1993-05-21 |
David Laffan |
Process for the preparation of substituted pentaalkylchromenes
|
SG43179A1
(en)
*
|
1991-12-18 |
1997-10-17 |
Warner Lambert Co |
A process for the prepatation of a solid dispersion
|
NO302471B1
(no)
*
|
1991-12-26 |
1998-03-09 |
Sankyo Co |
Tiazolidinforbindelser og farmasöytisk preparat
|
NO302519B1
(no)
*
|
1991-12-26 |
1998-03-16 |
Sankyo Co |
Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
|
CA2089013A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2, 5, 7, 8- tetraalkyl-2-(4-aminophenoxymethyl) chromans
|
CA2089012A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2,5,7,8-tetra- alkyl-2-(4-aminophenoxymethyl) chromans
|
DK0590793T3
(da)
*
|
1992-08-31 |
2000-01-31 |
Sankyo Co |
Oxazolidin-derivater med anti-diabetiske og anti-obesitas-egenskaber, fremstilling deraf samt deres terapeutiske anvendelse
|
JPH0631079U
(ja)
*
|
1992-09-22 |
1994-04-22 |
沖電線株式会社 |
シート付き小型smtコネクタ
|
US5594016A
(en)
*
|
1992-12-28 |
1997-01-14 |
Mitsubishi Chemical Corporation |
Naphthalene derivatives
|
WO1994019347A1
(en)
*
|
1993-02-24 |
1994-09-01 |
Sankyo Company, Limited |
Arteriosclerosis remedy
|
USRE39384E1
(en)
|
1993-09-01 |
2006-11-07 |
Smithkline Beecham P.L.C. |
Substituted thiazolidinedione derivatives
|
US5874454A
(en)
*
|
1993-09-15 |
1999-02-23 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
NZ274346A
(en)
*
|
1993-09-15 |
1997-06-24 |
Sankyo Co |
Use of various thiazolidine-2,4-dione and oxazolidine-2,4-dione derivatives to prevent or delay onset of non-insulin dependent diabetes mellitus
|
AU749416B2
(en)
*
|
1993-09-15 |
2002-06-27 |
Daiichi Sankyo Company, Limited |
Use of thiazolidinediones to prevent or delay onset of NIDDM
|
US6046222A
(en)
*
|
1993-09-15 |
2000-04-04 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
US5457109A
(en)
*
|
1993-09-15 |
1995-10-10 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
CA2157032C
(en)
*
|
1993-12-27 |
1999-09-28 |
Hisashi Shinkai |
Isoxazolidinedione derivative and use thereof
|
IL113313A
(en)
*
|
1994-04-11 |
1999-09-22 |
Sankyo Co |
Heterocyclic compounds and pharmaceutical compositions containing the same
|
US5594015A
(en)
*
|
1994-06-22 |
1997-01-14 |
Regents Of The University Of California |
Thiazolidine derivatives for the treatment of psoriasis
|
CZ261095A3
(en)
*
|
1994-10-07 |
1996-04-17 |
Sankyo Co |
Oxime derivatives, process of their preparation, pharmaceutical composition containing thereof and their use
|
US5708012A
(en)
*
|
1995-04-28 |
1998-01-13 |
Sankyo Company, Limited |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus
|
IL118474A
(en)
*
|
1995-06-01 |
2001-08-08 |
Sankyo Co |
Benzimideol derivatives and pharmaceutical preparations containing them
|
NZ286920A
(en)
*
|
1995-07-03 |
1997-06-24 |
Sankyo Co |
Use of combination of hmg-coa reductase inhibitors and of insulin sensitizers for the prevention/treatment of arteriosclerosis or xanthoma
|
HUP9802543A2
(hu)
*
|
1995-08-10 |
1999-07-28 |
Warner-Lambert Company |
Eljárás nem inzulinfüggő diabetes mellitusban szenvedő betegek esetében az adagolt exogén inzulin mennyiségének csökkentésére alkalmas tiazolindion-származékokat tartalmazó gyógyszerkészítmények előállítására
|
WO1997018811A1
(en)
*
|
1995-11-17 |
1997-05-29 |
Warner-Lambert Company |
A method of treating myotonic dystrophy
|
EP0783888A1
(en)
|
1995-12-26 |
1997-07-16 |
Sankyo Company Limited |
Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
|
IN182496B
(es)
*
|
1996-02-20 |
1999-04-17 |
Reddy Research Foundation |
|
IL120443A
(en)
*
|
1996-03-18 |
2000-07-16 |
Sankyo Co |
Use of an insulin sensitizer for the manufacture of a medicament for the treatment or prophylaxis of pancreatitis
|
WO1997037970A1
(fr)
*
|
1996-04-04 |
1997-10-16 |
Sankyo Company, Limited |
Derives d'acide phenylalkylcarboxylique
|
ATE231136T1
(de)
*
|
1996-04-09 |
2003-02-15 |
Reddys Lab Ltd Dr |
Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven eigenschaften, verfahren zu deren herstellung und pharmazeutischen zusammenstellungen, die sie enthalten
|
US5919782A
(en)
*
|
1996-05-06 |
1999-07-06 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
US5801173A
(en)
*
|
1996-05-06 |
1998-09-01 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
ZA973850B
(en)
*
|
1996-05-06 |
1997-12-02 |
Reddy Research Foundation |
Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
|
US5889032A
(en)
*
|
1996-05-06 |
1999-03-30 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
DE19619819A1
(de)
*
|
1996-05-16 |
1997-11-20 |
Boehringer Mannheim Gmbh |
Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltenden Arzneimittel
|
WO1997043283A1
(de)
*
|
1996-05-16 |
1997-11-20 |
Boehringer Mannheim Gmbh |
Neues verfahren zur herstellung von troglitazone
|
CA2257284C
(en)
*
|
1996-05-31 |
2005-10-04 |
Sankyo Company Limited |
Remedy for autoimmune diseases
|
GB9611947D0
(en)
*
|
1996-06-07 |
1996-08-07 |
Glaxo Group Ltd |
Medicaments
|
EP0844997A1
(en)
*
|
1996-06-19 |
1998-06-03 |
Dr. Reddy's Research Foundation |
Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation
|
US6372750B2
(en)
|
1996-07-01 |
2002-04-16 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
|
US6114526A
(en)
|
1996-07-01 |
2000-09-05 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
CA2258949C
(en)
*
|
1996-07-01 |
2008-05-06 |
Dr. Reddy's Research Foundation |
Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
US5885997A
(en)
*
|
1996-07-01 |
1999-03-23 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
USRE39266E1
(en)
*
|
1996-07-01 |
2006-09-05 |
Dr. Reddy's Laboratories, Limited |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
WO1998002159A1
(en)
*
|
1996-07-12 |
1998-01-22 |
Smithkline Beecham Plc |
Novel treatment of leptine resistance
|
IL128771A0
(en)
*
|
1996-09-12 |
2000-01-31 |
Sankyo Co |
An agent for enhancing the activity of glutathione reductase containing troglitazone and use thereof
|
ATE399545T1
(de)
*
|
1996-11-08 |
2008-07-15 |
Nippon Chemiphar Co |
Mittel zur verringerung der eigeweidefette
|
EP1006794B1
(en)
*
|
1997-03-12 |
2007-11-28 |
Robert W. Esmond |
A method for treating or preventing alzheimer's disease
|
US6011036A
(en)
*
|
1997-04-15 |
2000-01-04 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them
|
US6011031A
(en)
*
|
1997-05-30 |
2000-01-04 |
Dr. Reddy's Research Foundation |
Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
|
SE9702305D0
(sv)
*
|
1997-06-17 |
1997-06-17 |
Astra Ab |
New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
|
CA2294385C
(en)
*
|
1997-06-18 |
2007-06-05 |
Smithkline Beecham P.L.C. |
Treatment of diabetes with thiazolidinedione and sulphonylurea
|
WO1998057634A1
(en)
*
|
1997-06-18 |
1998-12-23 |
Smithkline Beecham Plc |
Treatment of diabetes with thiazolidinedione and metformin
|
GB9715295D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
GB9715306D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
US6171856B1
(en)
|
1997-07-30 |
2001-01-09 |
Board Of Regents, The University Of Texas System |
Methods and compositions relating to no-mediated cytotoxicity
|
FR2766820B1
(fr)
*
|
1997-07-31 |
1999-10-22 |
Rhodia Chimie Sa |
Procede de preparation de 2h-1-benzopyranes et intermediaires de synthese utiles dans la mise en oeuvre du procede
|
ID24376A
(id)
*
|
1997-10-02 |
2000-07-13 |
Sankyo Co |
Turunan-turunan asam amidokarboksilat
|
EP0916665A1
(de)
*
|
1997-11-11 |
1999-05-19 |
Lonza A.G. |
Verfahren zur Herstellung von Chromanderivaten
|
KR100567183B1
(ko)
*
|
1997-11-14 |
2006-06-13 |
론자 아게 |
포르밀이미다졸의제조방법
|
HUP9902721A2
(hu)
*
|
1997-11-25 |
1999-12-28 |
The Procter & Gamble Co. |
Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
|
AU1507799A
(en)
*
|
1997-12-16 |
1999-07-05 |
Sankyo Company Limited |
Leukemia remedy
|
US20040058873A1
(en)
*
|
1998-03-12 |
2004-03-25 |
Esmond Robert W. |
Method for treating or preventing Alzheimer's disease
|
CN1203846C
(zh)
|
1998-03-19 |
2005-06-01 |
布里斯托尔-迈尔斯斯奎布公司 |
高溶解性药物的双相控释递送系统和方法
|
WO2000007582A2
(en)
*
|
1998-08-06 |
2000-02-17 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives for the treatment or prevention of cataracts
|
AU5514199A
(en)
*
|
1998-08-19 |
2000-03-14 |
Sankyo Company Limited |
Process for the preparation of 2-(aryloxymethyl)-2,5,7,8-tetramethylchroman-6-ols
|
ID27833A
(id)
|
1998-09-17 |
2001-04-26 |
Bristol Myers Squibb Co |
METODA UNTUK MENGOBATI ATEROSKLEROSIS DENGAN MENGGUNAKAN INHIBITOR aP2 DAN KOMBINASINYA
|
US6028088A
(en)
*
|
1998-10-30 |
2000-02-22 |
The University Of Mississippi |
Flavonoid derivatives
|
AR023700A1
(es)
|
1998-11-12 |
2002-09-04 |
Smithkline Beecham Plc |
Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
|
GB9824893D0
(en)
*
|
1998-11-12 |
1999-01-06 |
Smithkline Beckman Corp |
Novel method of treatment
|
SI1131070T1
(sl)
|
1998-11-12 |
2008-12-31 |
Smithkline Beecham Plc |
Farmacevtski sestavek za modificirano sproĺ äśanje senzibilizatorja za inzulin in metformina
|
AU1740900A
(en)
*
|
1998-11-20 |
2000-06-13 |
Genentech Inc. |
Method of inhibiting angiogenesis
|
US6191154B1
(en)
|
1998-11-27 |
2001-02-20 |
Case Western Reserve University |
Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
|
US5968960A
(en)
*
|
1999-01-14 |
1999-10-19 |
The Regents Of The University Of California |
Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism
|
US6127394A
(en)
*
|
1999-03-08 |
2000-10-03 |
The University Of Mississippi |
1,2-Dithiolane derivatives
|
US6204288B1
(en)
|
1999-03-08 |
2001-03-20 |
The University Of Mississippi |
1,2-dithiolane derivatives
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
US7041691B1
(en)
*
|
1999-06-30 |
2006-05-09 |
Amgen Inc. |
Compounds for the modulation of PPARγ activity
|
JP2001072592A
(ja)
|
1999-07-01 |
2001-03-21 |
Kyowa Hakko Kogyo Co Ltd |
テロメラーゼ阻害剤
|
AR028299A1
(es)
|
1999-09-17 |
2003-05-07 |
Novartis Ag |
Una composicion farmaceutica que comprende nateglinida, un proceso para su preparacion y el uso de dicha composicion para la preparacion de un medicamento para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con diabetes.
|
US6559188B1
(en)
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
US6878749B2
(en)
|
1999-09-17 |
2005-04-12 |
Novartis Ag |
Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
|
US6586438B2
(en)
|
1999-11-03 |
2003-07-01 |
Bristol-Myers Squibb Co. |
Antidiabetic formulation and method
|
YU50302A
(sh)
|
1999-12-03 |
2006-01-16 |
Kyoto Pharmaceutical Industries Ltd. |
Nova heterociklična jedinjenja, njihove soli i njihova primena u medicini
|
DE122008000018I1
(de)
|
2000-01-21 |
2008-08-14 |
Novartis Pharma Ag |
Zusammensetzungen bestehend aus Dipeptidylpeptidase-IV Inhibitoren und Antidiabetica
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
US6680387B2
(en)
*
|
2000-04-24 |
2004-01-20 |
Aryx Therapeutics |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
US6958355B2
(en)
*
|
2000-04-24 |
2005-10-25 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
US6784199B2
(en)
*
|
2000-09-21 |
2004-08-31 |
Aryx Therapeutics |
Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis in mammals
|
AU6118001A
(en)
*
|
2000-05-03 |
2001-11-12 |
Tularik Inc |
Combination therapeutic compositions and methods of use
|
GB0014969D0
(en)
|
2000-06-19 |
2000-08-09 |
Smithkline Beecham Plc |
Novel method of treatment
|
US20030171399A1
(en)
*
|
2000-06-28 |
2003-09-11 |
Tularik Inc. |
Quinolinyl and benzothiazolyl modulators
|
IL154307A0
(en)
|
2000-08-07 |
2003-09-17 |
Ranbaxy Signature Llc |
Liquid formulation of metformin
|
FR2816840B1
(fr)
*
|
2000-11-17 |
2004-04-09 |
Flamel Tech Sa |
Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
|
US6452014B1
(en)
|
2000-12-22 |
2002-09-17 |
Geron Corporation |
Telomerase inhibitors and methods of their use
|
EP1385856B1
(en)
|
2001-04-11 |
2006-02-22 |
Bristol-Myers Squibb Company |
Amino acid complexes of c-aryl glucosides for treatment of diabetes and method
|
US20060047000A1
(en)
*
|
2001-04-24 |
2006-03-02 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
CA2448639A1
(en)
*
|
2001-05-29 |
2002-12-05 |
Kyoto Pharmaceutical Industries, Ltd. |
Novel heterocyclic derivatives and medicinal use thereof
|
ZA200309757B
(en)
*
|
2001-05-29 |
2004-12-22 |
Kyoto Pharma Ind |
Novel heterocyclic compound and medicinal use thereof.
|
JP4152641B2
(ja)
*
|
2001-08-07 |
2008-09-17 |
クラシエ製薬株式会社 |
チアゾリジン誘導体の副作用軽減剤
|
US8101209B2
(en)
*
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
FR2830447B1
(fr)
*
|
2001-10-09 |
2004-04-16 |
Flamel Tech Sa |
Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
EP1443919A4
(en)
*
|
2001-11-16 |
2006-03-22 |
Bristol Myers Squibb Co |
DOUBLE INHIBITORS OF THE FATTY ACID BINDING PROTEIN OF THE ADIPOCYTES AND THE FATTY ACID BINDING PROTEIN OF KERATINOCYTES
|
US7015345B2
(en)
*
|
2002-02-21 |
2006-03-21 |
Asahi Kasei Pharma Corporation |
Propionic acid derivatives
|
IL163666A0
(en)
|
2002-02-22 |
2005-12-18 |
New River Pharmaceuticals Inc |
Active agent delivery systems and methods for protecting and administering active agents
|
BRPI0309142C1
(pt)
|
2002-04-09 |
2021-05-25 |
Flamel Ireland Ltd |
suspensão de microcápsulas em uma fase líquida aquosa, que permite a liberação modificada de pelo menos um princípio ativo com exclusão da amoxicilina e que é destinada a ser administrada por via oral
|
AU2003246791A1
(en)
*
|
2002-04-09 |
2003-10-20 |
Flamel Technologies |
Oral suspension of amoxicillin capsules
|
EP1504525A2
(de)
*
|
2002-05-14 |
2005-02-09 |
Siemens Aktiengesellschaft |
Verfahren zum erzeugen eines sendesignals
|
US8268352B2
(en)
*
|
2002-08-05 |
2012-09-18 |
Torrent Pharmaceuticals Limited |
Modified release composition for highly soluble drugs
|
US8216609B2
(en)
*
|
2002-08-05 |
2012-07-10 |
Torrent Pharmaceuticals Limited |
Modified release composition of highly soluble drugs
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
WO2004066929A2
(en)
*
|
2003-01-24 |
2004-08-12 |
Bristol-Myers Squibb Company |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
US7851615B2
(en)
*
|
2003-04-17 |
2010-12-14 |
Alnylam Pharmaceuticals, Inc. |
Lipophilic conjugated iRNA agents
|
US8796436B2
(en)
|
2003-04-17 |
2014-08-05 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
US7723509B2
(en)
*
|
2003-04-17 |
2010-05-25 |
Alnylam Pharmaceuticals |
IRNA agents with biocleavable tethers
|
DK1620544T3
(en)
*
|
2003-04-17 |
2019-01-14 |
Alnylam Pharmaceuticals Inc |
MODIFIED iRNA AGENTS
|
US8017762B2
(en)
*
|
2003-04-17 |
2011-09-13 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
US20050004179A1
(en)
*
|
2003-05-22 |
2005-01-06 |
Pedersen Ward A. |
Methods and materials for treating, detecting, and reducing the risk of developing Alzheimer's Disease
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
US7371759B2
(en)
*
|
2003-09-25 |
2008-05-13 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7223761B2
(en)
*
|
2003-10-03 |
2007-05-29 |
Amgen Inc. |
Salts and polymorphs of a potent antidiabetic compound
|
JP5435841B2
(ja)
|
2003-11-12 |
2014-03-05 |
フェノミックス コーポレーション |
複素環式ボロン酸化合物
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7420059B2
(en)
*
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
JP2008505975A
(ja)
*
|
2004-07-12 |
2008-02-28 |
フェノミックス コーポレーション |
制約されたシアノ化合物
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
KR20070086007A
(ko)
*
|
2004-12-13 |
2007-08-27 |
다이이찌 산쿄 가부시키가이샤 |
당뇨병의 치료를 위한 의약 조성물
|
US7317024B2
(en)
|
2005-01-13 |
2008-01-08 |
Bristol-Myers Squibb Co. |
Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US7238702B2
(en)
*
|
2005-02-10 |
2007-07-03 |
Bristol-Myers Squibb Company |
Dihydroquinazolinones as 5HT modulators
|
US20070269486A1
(en)
*
|
2005-03-14 |
2007-11-22 |
Conor Medsystems, Llc. |
Methods and Devices for Reducing Tissue Damage After Ischemic Injury
|
JP2008533122A
(ja)
*
|
2005-03-18 |
2008-08-21 |
オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド |
新規なチロシン誘導体
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7888381B2
(en)
|
2005-06-14 |
2011-02-15 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
|
CA2617102A1
(en)
*
|
2005-07-28 |
2007-02-08 |
Bristol-Myers Squibb Company |
Substituted tetrahydro-1h-pyrido[4,3,b]indoles as serotonin receptor agonists and antagonists
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
US20080064884A1
(en)
*
|
2006-05-10 |
2008-03-13 |
Astrazeneca Ab |
Novel Process 1
|
WO2008057857A1
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
|
EP2089355A2
(en)
|
2006-11-01 |
2009-08-19 |
Brystol-Myers Squibb Company |
Modulators of glucocorticoid receptor, ap-1, and/or nf- kappa b activity and use thereof
|
EP2089389A2
(en)
|
2006-11-01 |
2009-08-19 |
Bristol-Myers Squibb Company |
Heterocyclic compounds as modulators of glucocorticoid receptor, ap-1, and/or nf-kappa-b activity
|
AU2008232937B2
(en)
|
2007-03-30 |
2012-09-27 |
Ambrx, Inc. |
Modified FGF-21 polypeptides and their uses
|
US20160331729A9
(en)
|
2007-04-11 |
2016-11-17 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
EP2612553B1
(en)
*
|
2007-04-11 |
2016-06-08 |
Omeros Corporation |
Compositions and Methods for Prophylaxis and Treatment of Addictions
|
US11241420B2
(en)
|
2007-04-11 |
2022-02-08 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
EP2527360B1
(en)
|
2007-06-04 |
2015-10-28 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
EP2209780B1
(en)
|
2007-11-01 |
2014-01-01 |
Bristol-Myers Squibb Company |
Nonsteroidal compounds useful as modulators of glucocorticoid receptor ap-1 and/or nf- kappa b activity and use thereof
|
ES2522968T3
(es)
|
2008-06-04 |
2014-11-19 |
Synergy Pharmaceuticals Inc. |
Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
WO2010009319A2
(en)
|
2008-07-16 |
2010-01-21 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
AR074897A1
(es)
|
2008-12-23 |
2011-02-23 |
Pharmasset Inc |
Fosforamidatos de nucleosidos
|
KR20110098849A
(ko)
*
|
2008-12-23 |
2011-09-01 |
파마셋 인코포레이티드 |
뉴클레오시드 유사체
|
US8716263B2
(en)
|
2008-12-23 |
2014-05-06 |
Gilead Pharmasset Llc |
Synthesis of purine nucleosides
|
NZ595545A
(en)
|
2009-03-11 |
2014-02-28 |
Omeros Corp |
Compositions and methods for prophylaxis and treatment of addictions
|
CA2787685A1
(en)
|
2010-01-22 |
2011-07-28 |
Dana-Farber Cancer Institute, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of metabolic disorders
|
TW201139457A
(en)
|
2010-03-31 |
2011-11-16 |
Pharmasset Inc |
Stereoselective synthesis of phosphorus containing actives
|
AU2011276254B2
(en)
|
2010-07-09 |
2016-11-03 |
James Trinca Green |
Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
|
WO2012027331A1
(en)
|
2010-08-27 |
2012-03-01 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
US20120094959A1
(en)
|
2010-10-19 |
2012-04-19 |
Bonnie Blazer-Yost |
Treatment of cystic diseases
|
US9486433B2
(en)
|
2012-10-12 |
2016-11-08 |
Mochida Pharmaceuticals Co. Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
EP2914250B1
(en)
|
2012-11-05 |
2018-04-04 |
Commissariat à l'Énergie Atomique et aux Énergies Alternatives |
Combination of an anti-cancer agent such as a tyrosinekinase inhibitor and a stat5 antagonist, preferably a thiazolidinedione, for eliminating hematologic cancer stem cells in vivo and for preventing hematologic cancer relapse
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
WO2014142364A2
(en)
|
2013-03-15 |
2014-09-18 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
CA2905435A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
US10441560B2
(en)
|
2013-03-15 |
2019-10-15 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
EA201592263A1
(ru)
|
2013-06-05 |
2016-05-31 |
Синерджи Фармасьютикалз, Инк. |
Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
CA2926685A1
(en)
|
2013-10-09 |
2015-04-16 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines
|
ES2874331T3
(es)
|
2014-10-24 |
2021-11-04 |
Bristol Myers Squibb Co |
Polipéptidos de FGF-21 modificados y usos de los mismos
|
US10034868B2
(en)
|
2014-11-04 |
2018-07-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
|
BR112021000139A2
(pt)
|
2018-07-19 |
2021-04-06 |
Astrazeneca Ab |
Métodos de tratamento da hfpef empregando dapagliflozina e composições compreendendo a mesma
|
WO2022022865A1
(en)
|
2020-07-27 |
2022-02-03 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
CN118510504A
(zh)
|
2022-01-26 |
2024-08-16 |
阿斯利康(瑞典)有限公司 |
用于在治疗糖尿病前期或降低发展2型糖尿病的风险中使用的达格列净
|