DK1254129T3 - Fremgangsmåde til fremstilling af 5-cyanophthalid - Google Patents

Fremgangsmåde til fremstilling af 5-cyanophthalid

Info

Publication number
DK1254129T3
DK1254129T3 DK00900501T DK00900501T DK1254129T3 DK 1254129 T3 DK1254129 T3 DK 1254129T3 DK 00900501 T DK00900501 T DK 00900501T DK 00900501 T DK00900501 T DK 00900501T DK 1254129 T3 DK1254129 T3 DK 1254129T3
Authority
DK
Denmark
Prior art keywords
sup
sub
cyanophthalide
preparation
alkyl
Prior art date
Application number
DK00900501T
Other languages
Danish (da)
English (en)
Inventor
Hans Petersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK1254129T3 publication Critical patent/DK1254129T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
DK00900501T 2000-01-14 2000-01-14 Fremgangsmåde til fremstilling af 5-cyanophthalid DK1254129T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/DK2000/000016 WO2001051477A1 (en) 2000-01-14 2000-01-14 Method for the preparation of 5-cyanophthalide

Publications (1)

Publication Number Publication Date
DK1254129T3 true DK1254129T3 (da) 2004-03-29

Family

ID=8149377

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00900501T DK1254129T3 (da) 2000-01-14 2000-01-14 Fremgangsmåde til fremstilling af 5-cyanophthalid

Country Status (27)

Country Link
US (1) US6911548B2 (no)
EP (1) EP1254129B1 (no)
JP (1) JP2003519691A (no)
KR (1) KR100660802B1 (no)
CN (1) CN1195749C (no)
AT (1) ATE252570T1 (no)
AU (1) AU3033700A (no)
CA (1) CA2397270C (no)
CZ (1) CZ20022601A3 (no)
DE (1) DE60006163T2 (no)
DK (1) DK1254129T3 (no)
EA (1) EA005134B1 (no)
ES (1) ES2206177T3 (no)
HK (1) HK1054392B (no)
HU (1) HUP0300343A2 (no)
IL (2) IL150561A0 (no)
IS (1) IS2168B (no)
IT (1) ITMI20010040A1 (no)
MX (1) MXPA02006915A (no)
NO (1) NO20023405L (no)
PL (1) PL197821B1 (no)
PT (1) PT1254129E (no)
SI (1) SI1254129T1 (no)
SK (1) SK286879B6 (no)
TR (1) TR200201783T2 (no)
UA (1) UA72569C2 (no)
WO (1) WO2001051477A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE237604T1 (de) * 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
DK1246812T3 (da) 1999-12-28 2004-07-05 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
CZ20022627A3 (cs) 1999-12-30 2002-10-16 H. Lundbeck A/S Způsob výroby citalopramu
UA72569C2 (uk) 2000-01-14 2005-03-15 Х. Луннбек А/С Спосіб одержання 5-ціанофталіду
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
MXPA02008869A (es) 2000-03-13 2003-02-10 Lundbeck & Co As H Metodo para la preparacion de citalopram.
MXPA02008684A (es) 2000-03-13 2003-02-24 Lundbeck & Co As H Alquilacion gradual de 1-(4-fluorofenil)-1,3-dihidroisobenzofuranos 5-substituidos.
EP1265882B1 (en) 2000-03-14 2004-01-14 H. Lundbeck A/S Method for the preparation of citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
AU2003239472A1 (en) * 2002-05-15 2003-12-02 Genzyme Corporation Synthesis of benzonitriles and benzimidates
WO2005111010A1 (en) * 2004-05-13 2005-11-24 Suven Life Sciences Ltd, An improved process for the preparation of 5-cyanophthalide
CN116022748B (zh) * 2022-12-16 2024-02-27 山东惟普新能源有限公司 一种含水双氟磺酰亚胺锂的除水方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (no) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
SK283309B6 (sk) 1997-07-08 2003-05-02 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
AU738359B2 (en) 1997-11-11 2001-09-13 H. Lundbeck A/S Method for the preparation of citalopram
DK1123284T3 (da) 1998-10-20 2003-04-28 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ES2195644T3 (es) 1998-12-23 2003-12-01 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida.
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
ATE237604T1 (de) 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
CH692298A5 (de) 1999-10-25 2002-04-30 Lundbeck & Co As H Verfahren zur Herstellung von Zwischenstufen für die Citalopramsynthese sowie zur Herstellung von Escitalopram.
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
DK1246812T3 (da) 1999-12-28 2004-07-05 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
CZ20022627A3 (cs) 1999-12-30 2002-10-16 H. Lundbeck A/S Způsob výroby citalopramu
UA72569C2 (uk) 2000-01-14 2005-03-15 Х. Луннбек А/С Спосіб одержання 5-ціанофталіду
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
FI20011621A (fi) 2000-08-18 2002-02-19 Lundbeck & Co As H Menetelmä sitalopraamin valmistamiseksi
NL1017525C1 (nl) 2000-12-22 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van zuiver Citalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro

Also Published As

Publication number Publication date
WO2001051477A1 (en) 2001-07-19
PT1254129E (pt) 2004-03-31
EA005134B1 (ru) 2004-12-30
IL150561A (en) 2007-07-04
CA2397270C (en) 2007-08-21
PL197821B1 (pl) 2008-04-30
SI1254129T1 (en) 2004-02-29
PL356712A1 (en) 2004-06-28
US20030013895A1 (en) 2003-01-16
IL150561A0 (en) 2003-02-12
CN1423643A (zh) 2003-06-11
KR100660802B1 (ko) 2006-12-26
CA2397270A1 (en) 2001-07-19
JP2003519691A (ja) 2003-06-24
ITMI20010040A1 (it) 2002-07-11
HK1054392A1 (en) 2003-11-28
EP1254129A1 (en) 2002-11-06
KR20020073501A (ko) 2002-09-26
CZ20022601A3 (cs) 2002-10-16
NO20023405D0 (no) 2002-07-15
TR200201783T2 (tr) 2002-12-23
IS6449A (is) 2002-06-28
SK286879B6 (sk) 2009-07-06
AU3033700A (en) 2001-07-24
MXPA02006915A (es) 2002-10-23
HUP0300343A2 (hu) 2003-06-28
EA200200758A1 (ru) 2002-12-26
IS2168B (is) 2006-11-15
CN1195749C (zh) 2005-04-06
NO20023405L (no) 2002-08-30
UA72569C2 (uk) 2005-03-15
ES2206177T3 (es) 2004-05-16
DE60006163T2 (de) 2004-04-15
HK1054392B (zh) 2005-11-18
DE60006163D1 (de) 2003-11-27
US6911548B2 (en) 2005-06-28
EP1254129B1 (en) 2003-10-22
SK11662002A3 (sk) 2003-01-09
ATE252570T1 (de) 2003-11-15

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