DK124950B - Analogous process for the preparation of 1-phenyl-4-alkyl-3H-1,4-benzodiazepine-2,5- [1H, 4H] -diones. - Google Patents

Analogous process for the preparation of 1-phenyl-4-alkyl-3H-1,4-benzodiazepine-2,5- [1H, 4H] -diones.

Info

Publication number
DK124950B
DK124950B DK566968AA DK566968A DK124950B DK 124950 B DK124950 B DK 124950B DK 566968A A DK566968A A DK 566968AA DK 566968 A DK566968 A DK 566968A DK 124950 B DK124950 B DK 124950B
Authority
DK
Denmark
Prior art keywords
diones
benzodiazepine
phenyl
alkyl
preparation
Prior art date
Application number
DK566968AA
Other languages
Danish (da)
Inventor
K Zeile
R Giesemann
K Weber
P Danneberg
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK124950B publication Critical patent/DK124950B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK566968AA 1967-11-24 1968-11-20 Analogous process for the preparation of 1-phenyl-4-alkyl-3H-1,4-benzodiazepine-2,5- [1H, 4H] -diones. DK124950B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (en) 1967-11-24 1967-11-24 Process for the preparation of new 1-phenyl-4-alkyl-3H-1,4-benzodiazepine-2,5- [1H, 4H] -diones

Publications (1)

Publication Number Publication Date
DK124950B true DK124950B (en) 1972-12-11

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK566968AA DK124950B (en) 1967-11-24 1968-11-20 Analogous process for the preparation of 1-phenyl-4-alkyl-3H-1,4-benzodiazepine-2,5- [1H, 4H] -diones.

Country Status (13)

Country Link
AT (1) AT280290B (en)
BE (1) BE724364A (en)
BR (1) BR6804236D0 (en)
CH (1) CH523265A (en)
DE (1) DE1810423B2 (en)
DK (1) DK124950B (en)
ES (2) ES360410A1 (en)
FR (2) FR1593335A (en)
GB (1) GB1173540A (en)
IE (1) IE32504B1 (en)
IL (1) IL31146A (en)
NL (1) NL6815755A (en)
SE (1) SE356979B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (en) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim New substituted 1,3-dihydro-2H-1 ^ -benzodiazepine ^ -ones
BE793460A (en) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim NEWS 1-ARYL-3H, 1,4-BENZODIAZEPINE-2,5- (1H
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7572788B2 (en) 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
IL146222A0 (en) * 1999-04-30 2002-07-25 Univ Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
CA2593019A1 (en) 2005-01-03 2006-07-13 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
WO2007053193A2 (en) 2005-06-01 2007-05-10 The Regents Of The University Of Michigan Unsolvated benzodiazepine compositions and methods
CA2779041A1 (en) 2005-11-01 2007-05-10 The Regents Of The University Of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
EP2037741B1 (en) 2006-06-09 2013-11-27 The Regents Of The University Of Michigan Benzodiazepine derivatives for use in the treatment of immune, inflammatory and proliferative disorders
EP2139331B1 (en) 2007-03-09 2013-02-20 The Regents of the University of Michigan Compositions and methods relating to novel compounds and targets thereof
AU2008251557B2 (en) * 2007-05-10 2012-12-06 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
CN101855203B (en) 2007-09-14 2014-03-19 密执安州立大学董事会 F1F0-ATPase inhibitors and related methods
UA99839C2 (en) 2007-11-06 2012-10-10 Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган Benzodiazepinone compounds useful in the treatment of skin conditions
WO2010030891A2 (en) 2008-09-11 2010-03-18 The Regents Of The University Of Michigan Aryl guanidine f1f0-atpase inhibitors and related methods
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
JP2013505258A (en) 2009-09-18 2013-02-14 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Benzodiazepinone compounds and therapeutic methods using the same
EP2501387B1 (en) 2009-11-17 2016-07-27 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
ES2703752T3 (en) 2009-11-17 2019-03-12 Univ Michigan Regents 1,4-Benzodiazepine-2,5-diones and related compounds that exhibit therapeutic properties
EP3043790B1 (en) * 2013-09-11 2021-05-26 The Administrators of the Tulane Educational Fund Novel anthranilic amides and the use thereof

Also Published As

Publication number Publication date
ES378977A1 (en) 1973-01-16
BR6804236D0 (en) 1973-02-08
IL31146A0 (en) 1969-01-29
DE1810423B2 (en) 1973-03-22
AT280290B (en) 1970-04-10
NL6815755A (en) 1969-05-28
BE724364A (en) 1969-05-22
DE1810423C3 (en) 1973-10-11
GB1173540A (en) 1969-12-10
IL31146A (en) 1972-04-27
FR1593335A (en) 1970-05-25
CH523265A (en) 1972-05-31
FR8310M (en) 1970-11-23
SE356979B (en) 1973-06-12
IE32504B1 (en) 1973-08-22
DE1810423A1 (en) 1969-10-09
IE32504L (en) 1969-05-24
ES360410A1 (en) 1970-11-01

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