DE3772423D1 - Verfahren zur herstellung von makrolidderivaten. - Google Patents

Verfahren zur herstellung von makrolidderivaten.

Info

Publication number
DE3772423D1
DE3772423D1 DE8787302663T DE3772423T DE3772423D1 DE 3772423 D1 DE3772423 D1 DE 3772423D1 DE 8787302663 T DE8787302663 T DE 8787302663T DE 3772423 T DE3772423 T DE 3772423T DE 3772423 D1 DE3772423 D1 DE 3772423D1
Authority
DE
Germany
Prior art keywords
macrolide derivatives
producing macrolide
producing
derivatives
macrolide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787302663T
Other languages
English (en)
Inventor
Eddie Vi-Ping Tao
Jeffrey Thomas Vicenzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3772423D1 publication Critical patent/DE3772423D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE8787302663T 1986-03-31 1987-03-27 Verfahren zur herstellung von makrolidderivaten. Expired - Lifetime DE3772423D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/846,446 US4921947A (en) 1986-03-31 1986-03-31 Process for preparing macrolide derivatives

Publications (1)

Publication Number Publication Date
DE3772423D1 true DE3772423D1 (de) 1991-10-02

Family

ID=25297965

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787302663T Expired - Lifetime DE3772423D1 (de) 1986-03-31 1987-03-27 Verfahren zur herstellung von makrolidderivaten.

Country Status (21)

Country Link
US (1) US4921947A (de)
EP (1) EP0240264B1 (de)
JP (1) JPH0710876B2 (de)
KR (1) KR900001166B1 (de)
CN (1) CN1018647B (de)
AR (1) AR247402A1 (de)
AT (1) ATE66678T1 (de)
AU (1) AU593894B2 (de)
CA (1) CA1292737C (de)
DE (1) DE3772423D1 (de)
DK (1) DK172935B1 (de)
EG (1) EG18550A (de)
ES (1) ES2028865T3 (de)
GR (1) GR3002764T3 (de)
HK (1) HK82492A (de)
HU (1) HU199864B (de)
IE (1) IE61018B1 (de)
IL (1) IL82005A (de)
NZ (1) NZ219784A (de)
PT (1) PT84561B (de)
ZA (1) ZA872201B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2638458A1 (fr) * 1988-10-27 1990-05-04 Adir Nouveaux derives de la tylosine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5354708A (en) * 1992-06-04 1994-10-11 Taskar Nikhil R Method of nitrogen doping of II-VI semiconductor compounds during epitaxial growth using an amine
TW226373B (de) * 1992-07-15 1994-07-11 Pfizer
US5677287A (en) * 1993-03-18 1997-10-14 Pfizer Inc. Antibacterial 16-membered ring macrolides containing olefins at C-20
WO1995002594A1 (en) * 1993-07-15 1995-01-26 Pfizer Inc. Amide derivatives of 16-membered ring antibiotic macrolides
ES2076107B1 (es) * 1993-09-20 1996-04-01 Pfizer Derivados de antibioticos macrolidos de anillos de 16 miembros.
EP0778283A3 (de) * 1995-12-05 1998-01-28 Pfizer Inc. Antibiotische Makrolide
DE102004027417A1 (de) * 2004-06-04 2005-12-22 Basf Ag Verbundelement
EA019504B1 (ru) 2005-12-13 2014-04-30 Инсайт Корпорейшн ГЕТЕРОАРИЛЗАМЕЩЕННЫЕ ПИРРОЛО[2,3-b]ПИРИДИНЫ И ПИРРОЛО[2,3-b]ПИРИМИДИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ ЯНУС-КИНАЗЫ
CN103193840A (zh) * 2006-05-01 2013-07-10 大正制药株式会社 大环内酯衍生物
CN102875622B (zh) * 2006-07-28 2016-12-07 英特威国际有限公司 大环内酯合成方法
EP2019112A1 (de) * 2007-07-26 2009-01-28 Intervet International BV Festkörper-Makrolidformen
KR101538599B1 (ko) * 2006-07-28 2015-07-21 인터벳 인터내셔널 비.브이. 마크롤라이드 합성 방법
WO2012068440A1 (en) 2010-11-19 2012-05-24 Incyte Corporation Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
JP5917545B2 (ja) 2010-11-19 2016-05-18 インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ Ｊａｋ阻害剤としてのシクロブチル置換ピロロピリジンおよびピロロピリミジン誘導体
US8691807B2 (en) 2011-06-20 2014-04-08 Incyte Corporation Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors
BR112014012585B1 (pt) 2011-11-25 2021-05-25 Bayer Intellectual Property Gmbh composto compreendendo derivados de tilosina, método de preparo do mesmo e composição farmacêutica ou veterinária
CN102382159B (zh) * 2011-12-07 2013-11-13 齐鲁动物保健品有限公司 一种替米考星的制备方法
KR102366356B1 (ko) 2013-03-06 2022-02-23 인사이트 홀딩스 코포레이션 Jak 저해제를 제조하기 위한 방법 및 중간생성물
BR112015029260A2 (pt) * 2013-05-23 2017-07-25 Bayer Animal Health Gmbh derivados de tilosina e seu método de preparação
CN105837648B (zh) * 2015-11-02 2018-07-06 湖北龙翔药业科技股份有限公司 一种磷酸替米考星的制备方法
CN108299531B (zh) * 2018-01-23 2021-02-05 郑州大学 甲哌泰万菌素可药用盐及其制备方法
CN111269275A (zh) * 2020-03-09 2020-06-12 浙江康牧药业有限公司 一种替米考星的制备方法
CN117304241B (zh) * 2023-11-30 2024-03-01 中国农业科学院饲料研究所 一种大环内酯类化合物及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
JPS58146595A (ja) * 1982-02-25 1983-09-01 Satoshi Omura マクロライド系抗生物質
US4454314A (en) * 1982-08-02 1984-06-12 Pfizer Inc. Antibacterial mycaminosyl tylonolide and related macrolide derivatives
IL69666A (en) * 1982-09-13 1987-10-20 Lilly Co Eli 20-amino-20-deoxo-5-o-mycaminosyl-23-o-mycinosyltylonolide derivatives,their preparation and veterinary antibiotic use
US4443436A (en) * 1982-09-13 1984-04-17 Eli Lilly And Company C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin
US4468511A (en) * 1983-02-28 1984-08-28 Eli Lilly And Company C-20- And C-23-Modified macrolide derivatives

Also Published As

Publication number Publication date
CA1292737C (en) 1991-12-03
DK154087A (da) 1987-10-01
CN1018647B (zh) 1992-10-14
IE61018B1 (en) 1994-09-07
IL82005A0 (en) 1987-10-20
JPS62240681A (ja) 1987-10-21
HK82492A (en) 1992-10-30
IE870796L (en) 1987-09-30
KR870008906A (ko) 1987-10-21
US4921947A (en) 1990-05-01
DK154087D0 (da) 1987-03-26
AR247402A1 (es) 1994-12-29
EP0240264A2 (de) 1987-10-07
IL82005A (en) 1991-08-16
DK172935B1 (da) 1999-10-11
AU7067087A (en) 1987-10-08
HU199864B (en) 1990-03-28
PT84561A (en) 1987-04-01
ATE66678T1 (de) 1991-09-15
AU593894B2 (en) 1990-02-22
EP0240264B1 (de) 1991-08-28
ES2028865T3 (es) 1992-07-16
CN87102397A (zh) 1987-10-07
HUT43087A (en) 1987-09-28
ZA872201B (en) 1988-10-26
EG18550A (en) 1993-10-30
PT84561B (pt) 1989-11-10
GR3002764T3 (en) 1993-01-25
EP0240264A3 (en) 1987-11-19
KR900001166B1 (ko) 1990-02-27
NZ219784A (en) 1989-01-27
JPH0710876B2 (ja) 1995-02-08

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Legal Events

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8364 No opposition during term of opposition