DE3780704D1 - Verfahren zur herstellung von n-acyltetrahydroisochinoline. - Google Patents

Verfahren zur herstellung von n-acyltetrahydroisochinoline.

Info

Publication number
DE3780704D1
DE3780704D1 DE8787303217T DE3780704T DE3780704D1 DE 3780704 D1 DE3780704 D1 DE 3780704D1 DE 8787303217 T DE8787303217 T DE 8787303217T DE 3780704 T DE3780704 T DE 3780704T DE 3780704 D1 DE3780704 D1 DE 3780704D1
Authority
DE
Germany
Prior art keywords
acyltetrahydroisochinoline
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787303217T
Other languages
English (en)
Other versions
DE3780704T2 (de
Inventor
Ryoji Noyori
Masato Kitamura
Hidemasa Takaya
Hidenori Kumobayashi
Susumu Akutagawa Sus Akutagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takasago International Corp
Original Assignee
Takasago Perfumery Industry Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takasago Perfumery Industry Co filed Critical Takasago Perfumery Industry Co
Application granted granted Critical
Publication of DE3780704D1 publication Critical patent/DE3780704D1/de
Publication of DE3780704T2 publication Critical patent/DE3780704T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8787303217T 1986-05-13 1987-04-13 Verfahren zur herstellung von n-acyltetrahydroisochinoline. Expired - Fee Related DE3780704T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61108889A JPS62265266A (ja) 1986-05-13 1986-05-13 Ｎ−アシル−テトラヒドロイソキノリン類の製造法

Publications (2)

Publication Number Publication Date
DE3780704D1 true DE3780704D1 (de) 1992-09-03
DE3780704T2 DE3780704T2 (de) 1993-01-28

Family

ID=14496171

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787303217T Expired - Fee Related DE3780704T2 (de) 1986-05-13 1987-04-13 Verfahren zur herstellung von n-acyltetrahydroisochinoline.

Country Status (4)

Country Link
US (1) US4851537A (de)
EP (1) EP0245960B1 (de)
JP (1) JPS62265266A (de)
DE (1) DE3780704T2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0295531B1 (de) * 1987-06-16 1993-03-24 F. Hoffmann-La Roche Ag Hydrogenationsverfahren
DK168069B1 (da) * 1987-11-11 1994-01-31 Hoffmann La Roche Isoquinolinderivater og en fremgangsmaade til fremstilling af octahydroisoquinoliner ud fra derivaterne
JPH02276A (ja) * 1987-11-25 1990-01-05 Sankyo Co Ltd β−ラクタム化合物の製造法
ATE126510T1 (de) * 1989-05-10 1995-09-15 Hoffmann La Roche Herstellung von isochinolinderivaten.
US5362736A (en) * 1991-02-27 1994-11-08 Banyu Pharmaceutical Co., Ltd. Isoquinoline derivatives
US5124337A (en) * 1991-05-20 1992-06-23 Schering Corporation N-acyl-tetrahydroisoquinolines as inhibitors of acyl-coenzyme a:cholesterol acyl transferase
US5238935A (en) * 1991-05-20 1993-08-24 Schering Corporation N-acyl-tetrahydroisoquinolines as inhibitors of acyl-coenzyme A: cholesterol acyl transferase
AU2002226687B9 (en) 2001-01-26 2005-10-20 Btg International Limited Benzylamine analogue
CN101638387A (zh) * 2006-12-12 2010-02-03 马林克罗特公司 由1,2,3,4-四氢异喹啉制备六氢异喹啉的方法
BRPI0808272A2 (pt) * 2007-03-08 2014-07-08 Chemagis Ltd "método para cromatograficamente separar o isômero 1r-cis, 1´r-cis de uma mistura de isômeros de (1r-1'r) - atracúrio, besilato de cisatracúrio e isômero 1r-cis, 1'r-cis do besilato de cisatracúrio"
CA2681060A1 (en) * 2007-03-26 2008-10-02 Chemagis Ltd. (1r,1'r)-atracurium salts separation process
WO2008132746A1 (en) * 2007-05-01 2008-11-06 Chemagis Ltd. Novel isoquinolinium compounds useful in the preparation of cisatracurium and associated intermediates
EP2155684B1 (de) * 2007-05-01 2014-04-09 Chemagis Ltd. Verfahren zur herstellung von cisatracuriumverbindungen und damit assoziierte zwischenprodukte
EP2132181A1 (de) * 2007-06-18 2009-12-16 Chemagis Ltd. Verfahren zur auftrennung von (1r,1'r)-atracuriumsalzen
BRPI0812625A2 (pt) * 2007-07-09 2019-02-19 Chemagis Ltd processo para preparar um sal de cis-atracúrio
EP2197848A1 (de) * 2007-10-29 2010-06-23 Chemagis Ltd. Neuartige r,r'-atracurium-salze
AU2009241211A1 (en) * 2008-05-01 2009-11-05 Chemagis Ltd. Cisatracurium derivatives, preparation and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1250828B (de) * 1962-10-10 1967-09-28 Chinoin Gyogyszer es Vegyeszeti Termekek Gyära R.T., Budapest Verfahren zur Herstellung des spasmolytisch wirksamen 6,7,3',4' - Tetraäthoxy -l-benzyliden-1,2,3,4tetrahydroisochinolins und seiner Salze
JPS6163690A (ja) * 1984-09-04 1986-04-01 Takasago Corp ルテニウム−ホスフイン錯体

Also Published As

Publication number Publication date
DE3780704T2 (de) 1993-01-28
JPH0368022B2 (de) 1991-10-25
JPS62265266A (ja) 1987-11-18
EP0245960A2 (de) 1987-11-19
EP0245960B1 (de) 1992-07-29
US4851537A (en) 1989-07-25
EP0245960A3 (en) 1988-12-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee