DD143613A5 - Verfahren zur herstellung von 4-amino-2-piperidino-chinazolin-derivaten - Google Patents

Verfahren zur herstellung von 4-amino-2-piperidino-chinazolin-derivaten Download PDF

Info

Publication number
DD143613A5
DD143613A5 DD79213010A DD21301079A DD143613A5 DD 143613 A5 DD143613 A5 DD 143613A5 DD 79213010 A DD79213010 A DD 79213010A DD 21301079 A DD21301079 A DD 21301079A DD 143613 A5 DD143613 A5 DD 143613A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
hydrochloride
preparation
piperidine
amino
Prior art date
Application number
DD79213010A
Other languages
German (de)
English (en)
Inventor
Simon F Campbell
John Ch Danilewicz
Colin W Greengrass
Rhona M Plews
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DD143613A5 publication Critical patent/DD143613A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DD79213010A 1978-05-18 1979-05-18 Verfahren zur herstellung von 4-amino-2-piperidino-chinazolin-derivaten DD143613A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2035178 1978-05-18

Publications (1)

Publication Number Publication Date
DD143613A5 true DD143613A5 (de) 1980-09-03

Family

ID=10144517

Family Applications (1)

Application Number Title Priority Date Filing Date
DD79213010A DD143613A5 (de) 1978-05-18 1979-05-18 Verfahren zur herstellung von 4-amino-2-piperidino-chinazolin-derivaten

Country Status (30)

Country Link
US (1) US4243666A (fr)
JP (1) JPS554370A (fr)
AR (2) AR223487A1 (fr)
AT (1) ATA363379A (fr)
AU (1) AU512947B2 (fr)
BE (1) BE876297A (fr)
CA (1) CA1240325A (fr)
CH (1) CH643553A5 (fr)
CS (1) CS214796B2 (fr)
DD (1) DD143613A5 (fr)
DE (1) DE2919800A1 (fr)
DK (1) DK159079A (fr)
ES (2) ES480671A1 (fr)
FI (1) FI64589C (fr)
FR (1) FR2434162A1 (fr)
GR (1) GR72824B (fr)
HU (1) HU182562B (fr)
IL (1) IL57297A (fr)
IN (1) IN153045B (fr)
IT (1) IT1114222B (fr)
LU (1) LU81284A1 (fr)
NL (1) NL172157C (fr)
NO (1) NO791648L (fr)
NZ (1) NZ190465A (fr)
PH (1) PH14802A (fr)
PL (2) PL120651B1 (fr)
PT (1) PT69622A (fr)
SE (1) SE439306B (fr)
YU (2) YU115279A (fr)
ZA (1) ZA792390B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607034A (en) * 1979-10-29 1986-08-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinazoline derivatives and pharmaceutical composition thereof
JPS5962766U (ja) * 1982-06-30 1984-04-25 守田　智 小動物用給水器
GB8414518D0 (en) * 1984-06-07 1984-07-11 Pfizer Ltd Therapeutic agents
US5801195A (en) * 1994-12-30 1998-09-01 Celgene Corporation Immunotherapeutic aryl amides
US6248888B1 (en) 1997-11-14 2001-06-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of terazosin hydrochloride dihydrate
KR20030069218A (ko) * 2001-01-18 2003-08-25 다케다 야쿠힌 고교 가부시키가이샤 벤질피페리딘 화합물의 제조 방법
US6746460B2 (en) * 2002-08-07 2004-06-08 Satiety, Inc. Intra-gastric fastening devices
BRPI0415683A (pt) * 2003-11-03 2006-12-19 Warner Lambert Co inibidores da reabsorção de norepinefrina para o tratamento de distúrbios do sistema nervoso central
WO2008045564A2 (fr) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Composés de carboxamide et leur utilisation
KR101441930B1 (ko) * 2007-04-04 2014-09-19 시플라 리미티드 에르로티닙 및 그의 약학적으로 허용가능한 염의 제조방법
CN101925383A (zh) 2007-12-11 2010-12-22 赛特帕斯凡德株式会社 甲酰胺化合物及其作为趋化因子受体激动剂的应用
CA2737587C (fr) * 2008-11-14 2016-08-09 F. Hoffmann-La Roche Ag Derives de quinazoline comme antagonistes des recepteurs nk3

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
FR2321890A1 (fr) * 1975-08-26 1977-03-25 Synthelabo Nouveaux derives de la quinazoline, leurs sels, leur preparation et les medicaments qui en renferment
DK140695C (da) * 1976-05-07 1980-05-12 Synthelabo Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf

Also Published As

Publication number Publication date
GR72824B (fr) 1983-12-06
AU4710179A (en) 1979-11-22
PT69622A (en) 1979-06-01
AR223487A1 (es) 1981-08-31
PH14802A (en) 1981-12-14
CS214796B2 (en) 1982-05-28
IN153045B (fr) 1984-05-26
ES8101584A1 (es) 1980-12-16
HU182562B (en) 1984-02-28
CH643553A5 (de) 1984-06-15
AU512947B2 (en) 1980-11-06
FI64589B (fi) 1983-08-31
NZ190465A (en) 1981-05-01
LU81284A1 (fr) 1980-12-16
ATA363379A (de) 1983-05-15
IL57297A0 (en) 1979-09-30
FR2434162B1 (fr) 1983-04-22
FR2434162A1 (fr) 1980-03-21
YU256382A (en) 1983-04-30
BE876297A (fr) 1979-11-16
JPS5623992B2 (fr) 1981-06-03
CA1240325A (fr) 1988-08-09
IT7922720A0 (it) 1979-05-16
DK159079A (da) 1979-11-19
NO791648L (no) 1979-11-20
SE7904358L (sv) 1979-11-19
NL7903853A (nl) 1979-11-20
FI791562A (fi) 1979-11-19
US4243666A (en) 1981-01-06
ES480671A1 (es) 1980-08-16
YU115279A (en) 1983-04-30
PL120651B1 (en) 1982-03-31
PL121158B1 (en) 1982-04-30
AR224784A1 (es) 1982-01-15
JPS554370A (en) 1980-01-12
FI64589C (fi) 1983-12-12
PL215626A1 (fr) 1980-08-25
PL223844A1 (fr) 1981-01-02
ZA792390B (en) 1980-07-30
ES488210A0 (es) 1980-12-16
NL172157B (nl) 1983-02-16
IL57297A (en) 1983-02-23
DE2919800A1 (de) 1979-11-22
IT1114222B (it) 1986-01-27
SE439306B (sv) 1985-06-10
NL172157C (nl) 1983-07-18

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