FR2434162A1 - Nouveaux derives de 4-amino-2-piperidino-quinazoline, leur procede de production et medicament les contenant - Google Patents

Nouveaux derives de 4-amino-2-piperidino-quinazoline, leur procede de production et medicament les contenant

Info

Publication number
FR2434162A1
FR2434162A1 FR7912635A FR7912635A FR2434162A1 FR 2434162 A1 FR2434162 A1 FR 2434162A1 FR 7912635 A FR7912635 A FR 7912635A FR 7912635 A FR7912635 A FR 7912635A FR 2434162 A1 FR2434162 A1 FR 2434162A1
Authority
FR
France
Prior art keywords
piperidino
amino
novel
production process
quinazoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7912635A
Other languages
English (en)
Other versions
FR2434162B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Pfizer Inc
Original Assignee
Pfizer Corp
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp, Pfizer Inc filed Critical Pfizer Corp
Publication of FR2434162A1 publication Critical patent/FR2434162A1/fr
Application granted granted Critical
Publication of FR2434162B1 publication Critical patent/FR2434162B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

L'invention a trait au domaine de la chimie pharmaceutique. Elle concerne des dérivés nouveaux de 4-amino-2-pipéridino-quinazoline, leur procédé de préparation et des compositions pharmaceutiques qui les contiennent. Les nouveaux composés de l'invention sont utiles comme régulateurs du système cardiovasculaire, notamment dans le traitement de l'hypertension.
FR7912635A 1978-05-18 1979-05-17 Nouveaux derives de 4-amino-2-piperidino-quinazoline, leur procede de production et medicament les contenant Granted FR2434162A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2035178 1978-05-18

Publications (2)

Publication Number Publication Date
FR2434162A1 true FR2434162A1 (fr) 1980-03-21
FR2434162B1 FR2434162B1 (fr) 1983-04-22

Family

ID=10144517

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7912635A Granted FR2434162A1 (fr) 1978-05-18 1979-05-17 Nouveaux derives de 4-amino-2-piperidino-quinazoline, leur procede de production et medicament les contenant

Country Status (30)

Country Link
US (1) US4243666A (fr)
JP (1) JPS554370A (fr)
AR (2) AR223487A1 (fr)
AT (1) ATA363379A (fr)
AU (1) AU512947B2 (fr)
BE (1) BE876297A (fr)
CA (1) CA1240325A (fr)
CH (1) CH643553A5 (fr)
CS (1) CS214796B2 (fr)
DD (1) DD143613A5 (fr)
DE (1) DE2919800A1 (fr)
DK (1) DK159079A (fr)
ES (2) ES480671A1 (fr)
FI (1) FI64589C (fr)
FR (1) FR2434162A1 (fr)
GR (1) GR72824B (fr)
HU (1) HU182562B (fr)
IL (1) IL57297A (fr)
IN (1) IN153045B (fr)
IT (1) IT1114222B (fr)
LU (1) LU81284A1 (fr)
NL (1) NL172157C (fr)
NO (1) NO791648L (fr)
NZ (1) NZ190465A (fr)
PH (1) PH14802A (fr)
PL (2) PL120651B1 (fr)
PT (1) PT69622A (fr)
SE (1) SE439306B (fr)
YU (2) YU115279A (fr)
ZA (1) ZA792390B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607034A (en) * 1979-10-29 1986-08-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinazoline derivatives and pharmaceutical composition thereof
JPS5962766U (ja) * 1982-06-30 1984-04-25 守田　智 小動物用給水器
GB8414518D0 (en) * 1984-06-07 1984-07-11 Pfizer Ltd Therapeutic agents
US5801195A (en) * 1994-12-30 1998-09-01 Celgene Corporation Immunotherapeutic aryl amides
US6248888B1 (en) 1997-11-14 2001-06-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of terazosin hydrochloride dihydrate
KR20030069218A (ko) * 2001-01-18 2003-08-25 다케다 야쿠힌 고교 가부시키가이샤 벤질피페리딘 화합물의 제조 방법
US6746460B2 (en) * 2002-08-07 2004-06-08 Satiety, Inc. Intra-gastric fastening devices
BRPI0415683A (pt) * 2003-11-03 2006-12-19 Warner Lambert Co inibidores da reabsorção de norepinefrina para o tratamento de distúrbios do sistema nervoso central
WO2008045564A2 (fr) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Composés de carboxamide et leur utilisation
KR101441930B1 (ko) * 2007-04-04 2014-09-19 시플라 리미티드 에르로티닙 및 그의 약학적으로 허용가능한 염의 제조방법
CN101925383A (zh) 2007-12-11 2010-12-22 赛特帕斯凡德株式会社 甲酰胺化合物及其作为趋化因子受体激动剂的应用
CA2737587C (fr) * 2008-11-14 2016-08-09 F. Hoffmann-La Roche Ag Derives de quinazoline comme antagonistes des recepteurs nk3

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
FR2321890A1 (fr) * 1975-08-26 1977-03-25 Synthelabo Nouveaux derives de la quinazoline, leurs sels, leur preparation et les medicaments qui en renferment
DK140695C (da) * 1976-05-07 1980-05-12 Synthelabo Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf

Also Published As

Publication number Publication date
GR72824B (fr) 1983-12-06
AU4710179A (en) 1979-11-22
PT69622A (en) 1979-06-01
AR223487A1 (es) 1981-08-31
PH14802A (en) 1981-12-14
CS214796B2 (en) 1982-05-28
IN153045B (fr) 1984-05-26
ES8101584A1 (es) 1980-12-16
HU182562B (en) 1984-02-28
CH643553A5 (de) 1984-06-15
AU512947B2 (en) 1980-11-06
DD143613A5 (de) 1980-09-03
FI64589B (fi) 1983-08-31
NZ190465A (en) 1981-05-01
LU81284A1 (fr) 1980-12-16
ATA363379A (de) 1983-05-15
IL57297A0 (en) 1979-09-30
FR2434162B1 (fr) 1983-04-22
YU256382A (en) 1983-04-30
BE876297A (fr) 1979-11-16
JPS5623992B2 (fr) 1981-06-03
CA1240325A (fr) 1988-08-09
IT7922720A0 (it) 1979-05-16
DK159079A (da) 1979-11-19
NO791648L (no) 1979-11-20
SE7904358L (sv) 1979-11-19
NL7903853A (nl) 1979-11-20
FI791562A (fi) 1979-11-19
US4243666A (en) 1981-01-06
ES480671A1 (es) 1980-08-16
YU115279A (en) 1983-04-30
PL120651B1 (en) 1982-03-31
PL121158B1 (en) 1982-04-30
AR224784A1 (es) 1982-01-15
JPS554370A (en) 1980-01-12
FI64589C (fi) 1983-12-12
PL215626A1 (fr) 1980-08-25
PL223844A1 (fr) 1981-01-02
ZA792390B (en) 1980-07-30
ES488210A0 (es) 1980-12-16
NL172157B (nl) 1983-02-16
IL57297A (en) 1983-02-23
DE2919800A1 (de) 1979-11-22
IT1114222B (it) 1986-01-27
SE439306B (sv) 1985-06-10
NL172157C (nl) 1983-07-18

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