CY1109610T1 - Παραγωγο βενζιμιδαζολης και η χρηση αυτου ως ανταγωνιστου του υποδοχεα αιι - Google Patents

Παραγωγο βενζιμιδαζολης και η χρηση αυτου ως ανταγωνιστου του υποδοχεα αιι

Info

Publication number
CY1109610T1
CY1109610T1 CY20091101184T CY091101184T CY1109610T1 CY 1109610 T1 CY1109610 T1 CY 1109610T1 CY 20091101184 T CY20091101184 T CY 20091101184T CY 091101184 T CY091101184 T CY 091101184T CY 1109610 T1 CY1109610 T1 CY 1109610T1
Authority
CY
Cyprus
Prior art keywords
receptor antagonist
benzimidazole derivative
formula
benzimidazole
derivative
Prior art date
Application number
CY20091101184T
Other languages
English (en)
Inventor
Takanobu Kuroita
Hiroki Sakamoto
Mami Ojima
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34858222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1109610(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of CY1109610T1 publication Critical patent/CY1109610T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με ένα φάρμακο που περιλαμβάνει μία ένωση που αναπαρίσταται μέσω του χημικού τύπου (I) στον οποίον το R1 είναι μία ομάδα που αναπαρίσταται μέσω του χημικού τύπου
CY20091101184T 2004-02-25 2009-11-12 Παραγωγο βενζιμιδαζολης και η χρηση αυτου ως ανταγωνιστου του υποδοχεα αιι CY1109610T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004048928 2004-02-25
US11/031,057 US7157584B2 (en) 2004-02-25 2005-01-07 Benzimidazole derivative and use thereof
EP07075609A EP1857457B1 (en) 2004-02-25 2005-02-23 Benzimidazole derivative and its use as AII receptor antagonist

Publications (1)

Publication Number Publication Date
CY1109610T1 true CY1109610T1 (el) 2014-08-13

Family

ID=34858222

Family Applications (5)

Application Number Title Priority Date Filing Date
CY20071101476T CY1107008T1 (el) 2004-02-25 2007-11-14 Παραγωγο βενζιμιδαζολης και χρηση ως ανταγωνιστου υποδοχεα aii
CY20091101184T CY1109610T1 (el) 2004-02-25 2009-11-12 Παραγωγο βενζιμιδαζολης και η χρηση αυτου ως ανταγωνιστου του υποδοχεα αιι
CY2012015C CY2012015I2 (el) 2004-02-25 2012-05-31 Παραγωγο βενζιμιδαζολης και χρηση ως ανταγωνιστου υποδοχεα aii
CY2012016C CY2012016I2 (el) 2004-02-25 2012-05-31 Παραγωγο βενζιμιδαζολης και χρηση ως ανταγωνιστου υποδοχεα aii
CY20121100774T CY1113084T1 (el) 2004-02-25 2012-08-29 ΠΑΡΑΓΩΓΟ ΒΕΝΖΙΜΙΔΑΖΟΛΗΣ ΚΑΙ Η ΧΡΗΣΗ ΑΥΤΟΥ ΩΣ ΑΝΤΑΓΩΝΙΣΤΟΥ ΤΟΥ ΥΠΟΔΟΧΕΑ aii

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20071101476T CY1107008T1 (el) 2004-02-25 2007-11-14 Παραγωγο βενζιμιδαζολης και χρηση ως ανταγωνιστου υποδοχεα aii

Family Applications After (3)

Application Number Title Priority Date Filing Date
CY2012015C CY2012015I2 (el) 2004-02-25 2012-05-31 Παραγωγο βενζιμιδαζολης και χρηση ως ανταγωνιστου υποδοχεα aii
CY2012016C CY2012016I2 (el) 2004-02-25 2012-05-31 Παραγωγο βενζιμιδαζολης και χρηση ως ανταγωνιστου υποδοχεα aii
CY20121100774T CY1113084T1 (el) 2004-02-25 2012-08-29 ΠΑΡΑΓΩΓΟ ΒΕΝΖΙΜΙΔΑΖΟΛΗΣ ΚΑΙ Η ΧΡΗΣΗ ΑΥΤΟΥ ΩΣ ΑΝΤΑΓΩΝΙΣΤΟΥ ΤΟΥ ΥΠΟΔΟΧΕΑ aii

Country Status (34)

Country Link
US (3) US7157584B2 (el)
EP (3) EP1857457B1 (el)
JP (2) JP4256852B2 (el)
KR (1) KR101080029B1 (el)
CN (2) CN101381366B (el)
AR (2) AR047972A1 (el)
AT (2) ATE370136T1 (el)
AU (1) AU2005214271B8 (el)
BE (1) BE2012C025I2 (el)
BR (2) BR122012009489B8 (el)
CA (1) CA2557538C (el)
CY (5) CY1107008T1 (el)
DE (3) DE602005002030T2 (el)
DK (3) DK2119715T3 (el)
ES (3) ES2331209T3 (el)
HK (2) HK1098472A1 (el)
HR (3) HRP20070510T3 (el)
HU (1) HUS1200008I1 (el)
IL (1) IL177533A (el)
LU (1) LU91962I2 (el)
MA (1) MA28478B1 (el)
ME (2) ME01089B (el)
MY (1) MY142807A (el)
NL (1) NL300802I2 (el)
NO (2) NO332344B1 (el)
NZ (1) NZ549755A (el)
PL (3) PL1718641T3 (el)
PT (3) PT2119715E (el)
RS (3) RS52376B (el)
RU (2) RU2501798C2 (el)
SI (3) SI2119715T1 (el)
TW (1) TWI336702B (el)
WO (1) WO2005080384A2 (el)
ZA (1) ZA200607241B (el)

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