호모 사피엔스 종의 단백질 코드 유전자
인터페론 알파/베타 수용체 알파 사슬은 IFNAR1 [5] [6] 단백질 이다.
기능. 이 유전자에 의해 코드된 단백질은 간섭자 알파, -β 및 -lambda를 포함한 I형 간섭자에 대한 수용체의 두 사슬 중 하나를 형성하는 I형 막 단백질이다. 수용체의 결합 및 활성화는 야누스 단백질 키나제를 자극하여 STAT1 및 STAT2를 포함한 여러 단백질을 인산화한다. 암호화된 단백질은 또한 항바이러스 [6]
상호 작용 IFNAR1은 다음과 상호작용하는 것 으로 나타났습니다.
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