KEGG   PATHWAY: ko00650
Entry
ko00650                     Pathway                                
Name
Butanoate metabolism
Class
Metabolism; Carbohydrate metabolism
Pathway map
ko00650  Butanoate metabolism
ko00650

Module
M00027  GABA (gamma-Aminobutyrate) shunt [PATH:ko00650]
M00088  Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone [PATH:ko00650]
Other DBs
GO: 0019605
Orthology
K00626  acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00074  3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
K00022  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K07516  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K01825  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
K01782  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01692  enoyl-CoA hydratase [EC:4.2.1.17]
K01715  enoyl-CoA hydratase [EC:4.2.1.17]
K07515  enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07511  enoyl-CoA hydratase [EC:4.2.1.17]
K00248  butyryl-CoA dehydrogenase [EC:1.3.8.1]
K00209  enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]
K17829  crotonyl-CoA reductase [EC:1.3.1.86]
K01034  acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
K01035  acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
K19709  acetate CoA-transferase [EC:2.8.3.8]
K23756  medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2]
K01896  medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01913  acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2]
K00929  butyrate kinase [EC:2.7.2.7]
K00634  phosphate butyryltransferase [EC:2.3.1.19]
K00132  acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10]
K04072  acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
K04073  acetaldehyde dehydrogenase [EC:1.2.1.10]
K18366  acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]
K00100  butanol dehydrogenase [EC:1.1.1.-]
K21317  butane monooxygenase alpha subunit [EC:1.14.13.230]
K21318  butane monooxygenase beta subunit [EC:1.14.13.230]
K21319  butane monooxygenase gamma subunit [EC:1.14.13.230]
K21320  butane monooxygenase reductase
K21321  butane monooxygenase regulatory protein
K21322  butane monooxygenase hypothetical assembly protein
K17865  3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
K03821  poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304]
K22881  poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE
K05973  poly(3-hydroxybutyrate) depolymerase [EC:3.1.1.75]
K00023  acetoacetyl-CoA reductase [EC:1.1.1.36]
K01615  glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5]
K20509  carboxybiotin decarboxylase [EC:7.2.4.1]
K23351  glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
K23352  glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit delta
K01039  glutaconate CoA-transferase, subunit A [EC:2.8.3.12]
K01040  glutaconate CoA-transferase, subunit B [EC:2.8.3.12]
K00109  2-hydroxyglutarate dehydrogenase [EC:1.1.99.2]
K07246  tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83]
K01799  maleate isomerase [EC:5.2.1.1]
K00239  succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240  succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241  succinate dehydrogenase cytochrome b subunit
K00242  succinate dehydrogenase membrane anchor subunit
K18859  succinate dehydrogenase subunit D
K18860  succinate dehydrogenase subunit D
K00244  succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00245  succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00246  succinate dehydrogenase subunit C
K00247  succinate dehydrogenase subunit D
K00233  succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]
K25995  succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]
K25996  succinate dehydrogenase subunit C
K26318  fumarate reductase (cytochrome) [EC:1.3.2.4]
K01580  glutamate decarboxylase [EC:4.1.1.15]
K00823  4-aminobutyrate aminotransferase [EC:2.6.1.19]
K14268  5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.48 2.6.1.19]
K07250  4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
K13524  4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
K16871  4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96]
K00135  succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
K00139  succinate-semialdehyde dehydrogenase [EC:1.2.1.24]
K17761  succinate-semialdehyde dehydrogenase, mitochondrial [EC:1.2.1.24]
K08324  succinate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.24]
K18118  succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
K18119  succinate-semialdehyde dehydrogenase [EC:1.2.1.76]
K18120  4-hydroxybutyrate dehydrogenase [EC:1.1.1.61]
K00043  4-hydroxybutyrate dehydrogenase [EC:1.1.1.61]
K08318  4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase [EC:1.1.1.61 1.1.1.373]
K18121  glyoxylate/succinic semialdehyde reductase [EC:1.1.1.79 1.1.1.-]
K18122  4-hydroxybutyrate CoA-transferase [EC:2.8.3.-]
K14534  4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
K00656  formate C-acetyltransferase [EC:2.3.1.54]
K00169  pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
K00170  pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
K00172  pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
K00189  2-oxoisovalerate/pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.7 1.2.7.1]
K00171  pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
K03737  pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
K00174  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
K00175  2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
K01641  hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
K01640  hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
K01027  3-oxoacid CoA-transferase [EC:2.8.3.5]
K01028  3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
K01029  3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
K01907  acetoacetyl-CoA synthetase [EC:6.2.1.16]
K00019  3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
K07518  hydroxybutyrate-dimer hydrolase [EC:3.1.1.22]
K01574  acetoacetate decarboxylase [EC:4.1.1.4]
K18223  propane 2-monooxygenase large subunit [EC:1.14.13.227]
K18224  propane 2-monooxygenase small subunit [EC:1.14.13.227]
K18226  propane monooxygenase coupling protein
K18225  propane monooxygenase reductase component [EC:1.18.1.-]
K23259  isopropanol dehydrogenase (NADP+) [EC:1.1.1.80]
K18382  NAD+-dependent secondary alcohol dehydrogenase Adh1 [EC:1.1.1.-]
K18369  alcohol dehydrogenase [EC:1.1.1.-]
K18370  alcohol dehydrogenase [EC:1.1.1.-]
K18371  acetone monooxygenase (methyl acetate-forming) [EC:1.14.13.226]
K18372  methyl acetate hydrolase [EC:3.1.1.114]
K01652  acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653  acetolactate synthase I/III small subunit [EC:2.2.1.6]
K11258  acetolactate synthase II small subunit [EC:2.2.1.6]
K01575  acetolactate decarboxylase [EC:4.1.1.5]
K00004  (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303]
K03366  meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]
K18009  meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00042  Succinate
C00091  Succinyl-CoA
C00122  Fumarate
C00132  Methanol
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00207  Acetone
C00232  Succinate semialdehyde
C00246  Butanoic acid
C00332  Acetoacetyl-CoA
C00334  4-Aminobutanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00497  (R)-Malate
C00741  Diacetyl
C00810  (R)-Acetoin
C00877  Crotonoyl-CoA
C00989  4-Hydroxybutanoic acid
C01089  (R)-3-Hydroxybutanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01384  Maleic acid
C01412  Butanal
C01769  (S)-Acetoin
C01845  Propan-2-ol
C02331  Vinylacetyl-CoA
C02411  Glutaconyl-1-CoA
C02527  Butanoylphosphate
C02630  2-Hydroxyglutarate
C03044  (R,R)-Butane-2,3-diol
C03046  (S,S)-Butane-2,3-diol
C03058  2-Hydroxyglutaryl-CoA
C03561  (R)-3-Hydroxybutanoyl-CoA
C04546  (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate
C06010  (S)-2-Acetolactate
C06142  1-Butanol
C06143  Poly-beta-hydroxybutyrate
C06144  3-Butynoate
C06145  3-Butyn-1-al
C06146  3-Butyn-1-ol
C11062  4-Hydroxybutyryl-CoA
C17530  Methyl acetate
C20657  meso-2,3-Butanediol
C20783  Propane
C21390  Butane
Related
pathway
ko00010  Glycolysis / Gluconeogenesis
ko00020  Citrate cycle (TCA cycle)
ko00250  Alanine, aspartate and glutamate metabolism
ko00330  Arginine and proline metabolism
ko00620  Pyruvate metabolism
ko00750  Vitamin B6 metabolism
ko01056  Biosynthesis of type II polyketide backbone
LinkDB

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