KEGG ENZYME: 1.1.1.80

ENZYME: 1.1.1.80

Entry

EC 1.1.1.80                 Enzyme

Name

isopropanol dehydrogenase (NADP+);
isopropanol dehydrogenase (NADP+)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

propan-2-ol:NADP+ oxidoreductase

Reaction(IUBMB)

propan-2-ol + NADP+ = acetone + NADPH + H+ [RN:R01550]

Reaction(KEGG)

R01550

Substrate

propan-2-ol [CPD:C01845];
NADP+ [CPD:C00006]

Product

acetone [CPD:C00207];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.

History

EC 1.1.1.80 created 1972

Pathway

ec00650

Butanoate metabolism

ec01100

Metabolic pathways

Orthology

K23259

isopropanol dehydrogenase (NADP+)

Genes

MGL:

MGL_3563

EHI:	EHI_023110(81.t00034)

EDI:	EDI_033780 EDI_125570 EDI_247390 EDI_322720

EIV:	EIN_184550

TVA:	TVAG_2v0231540 TVAG_2v0470960 TVAG_2v0592710

PSKY:

A6B44_02175

PATL:

KGI96_02165

XFA:

XF_1727

XFH:	XFHB_06515

HFE:	HFELIS_04520

HHM:	BN341_2080

HAD:	CDV25_07355

HSH:	NHP194022_03430(adh)

HAIL:

ASB7_13140(adh)

CAVI:

CAV_1667

ABU:

Abu_1042

ABT:

ABED_0990

ABL:	A7H1H_1038

AVP:	AVENP_1797

ADZ:	ADFLV_1732

ARC:

ABLL_1678

AANA:

AANAER_1370

DOA:	AXF15_06605

DEO:	CAY53_02390

KST:	KSMBR1_0080(adh_1)

TPED:

TPE_0836(mtnN)

TPK:	JO40_03945

TRM:	JO41_00510

TPHG:

FUT81_04210

TRI:	DYE50_08525

TPAV:

HRQ91_02290

TMED:

DWB79_11170

TSK:	HRI97_09700

SSM:	Spirs_1190

SCC:	Spico_1615

BHY:	BHWA1_01862(tdh)

BHD:	BHYOB78_06815

BRM:

Bmur_1378

BPO:	BP951000_1321(adh)

BPJ:	B2904_orf102(tdh)

BPIP:

BPP43_08500

BPW:	WESB_0114(tdh)

BIP:	Bint_0150(tdh)

PDN:	HMPREF9137_0305(aDH)

PFUS:

ADJ77_06970

PMUF:

J4864_05835

GOT:	AXE85_05885

GMO:	NCTC11323_00742(adh)

GEQ:	CG018_07820

GSA:	FOC50_07595

PDH:	B9T62_07995

LFE:	LAF_0972 LAF_1372

LFR:	LC40_0631 LC40_0864

LFF:	LBFF_1063 LBFF_1491

LOR:	AYI71_12045 AYI71_14075

LGAS:

LG045_00385

LPAS:

KZE55_03290

CBK:	CLL_A1797(adh)

CBB:	CLD_1638(adh)

CBF:	CLI_2960(adh)

CBM:

CBF_2952

CLJ:	CLJU_c24860

CPAS:

Clopa_1771

CAH:	CAETHG_0553

CSQ:

CSCA_1104

CTYK:

CTK_C28120(adhI)

CTAE:

BGI42_07605

CARG:

RSJ17_06360

CDRK:

B9W14_13250

CIA:	BEN51_01390

CDY:	F3K33_14815

CCOH:

SAMEA4530647_1599(adh)

CFER:

D4Z93_10405

CLOS:

DMR38_12850

CRW:	CROST_028370(adh_1)

CTHD:

CDO33_06050

CLO:	HMPREF0868_1158(aDH)

EHA:	Ethha_2217

OVA:	OBV_12380(adh)

PETR:

QKW49_18670

AIM:	PYS61_04990

ANQ:	PYS63_04105

SGY:

Sgly_3313

DCA:	Desca_0375 Desca_2553

DRU:	Desru_2988

BHU:

bhn_I0300

BPRO:

PMF13cell1_01309(adh_2)

BLIQ:

INP51_14750

CSH:	Closa_0574

LXA:	OW255_02500 OW255_03295

HSD:	SD1D_1259(adh)

LUA:	D4A81_01075

LGG:	QJR73_00100

ACEL:

acsn021_01250(adh)

RGN:	RGna_15335

CASP:

NQ535_24685

QDO:	H9Q78_07930 H9Q78_12360

STOM:

QU660_01460 QU660_03055

KIB:	RBB56_03920

CBIL:

EUBC25_11180(adh)

LBP:	V1224_12985

MDV:	C5Q96_00455

PEB:	O0R46_02780

TTE:	TTE0695(Tdh)

TEX:	Teth514_0653

THX:

Thet_2272

TPD:	Teth39_0218

TIT:

Thit_2177

TMT:	Tmath_2094

TBO:	Thebr_0224

TWI:	Thewi_1976 Thewi_2518

TKI:	TKV_c22260(adh)

THEZ:

OEI98_002736

BACG:

D2962_14415

NCD:	ACONDI_01845(adh)

HALS:

D7D81_08595

IFN:	GM661_06035

AVG:	I6H45_07990

AOB:	I6H46_01945

KPAR:

JL105_10205

TIZ:	RBU61_03990

PFT:

JBW_00677

STED:

SPTER_41430(adh)

AFN:	Acfer_0888

AIN:	Acin_0250(adh)

CALK:

HUE98_15725

FCZ:	IMF26_06360

MGB:	VO56_01055

MPUL:

BLA55_01525

MPN:	MPN_564(adh)

MPM:	MPNA5640 MPNA5641

FVG:	I6G91_05680

APV:

Apar_1228

OLS:

Olsu_0295

OLO:	ADJ70_00940

TIO:	INP52_07520

LCAL:

ATTO_05480(adh)

CGO:	Corgl_1434

COLL:

KPC83_05780

SNW:	BBN63_32685

PPC:	HMPREF9154_2301

BROO:

brsh051_20860

AUU:	CJ184_005340

ACTT:

DDD63_10810

ACQ:	AM609_01035

ABAO:

BEQ56_01815

ACO:	Amico_1354

AMIZ:

RBH88_03130

SBR:

SY1_03930

TLI:

Tlie_0160

PPIO:

CE91St28_08250

PYY:	RAH42_05135

LBA:

Lebu_1419

LEO:	AMK43_01010

LHF:	JCM16775_0994

LWD:	JCM16777_1389

LGO:	JCM16774_1651

MST:	Msp_0967(adh)

METB:

AW729_06385

MEIS:

PXD04_04575

MRU:	mru_0065(adh1) mru_1445(adh3)

MEYE:

TL18_05405 TL18_05580 TL18_09010

MOL:

YLM1_0947

MARO:

MarbSA_04680 MarbSA_15090

METV:

K4897_04415

MEW:	MSWAN_0857

MCUB:

MCBB_0894(adh)

METN:

BK008_07235

MEME:

HYG87_06875

MFEG:

GCM10025860_11620

TGY:	X802_04320

MBA:	Mbar_A2344

MBY:	MSBRM_1462

MBW:	MSBRW_2399

MBAR:

MSBR2_0939

MBAK:

MSBR3_1080

MAC:	MA_1901(adh)

MLS:	MSLAZ_1208

MEF:	MSWH1_1726

MEQ:	MSWHS_1589

MSJ:	MSSAC_2296

MSZ:	MSSIH_1875

MSW:	MSSIT_1932

MTHR:

MSTHT_0422

MTHE:

MSTHC_0299

MHOR:

MSHOH_1722 MSHOH_1729

MEHF:

MmiHf6_01920(adh_1) MmiHf6_11290(adh_2)

MEES:

MmiEs2_07980(adh_1) MmiEs2_14000(adh_2)

MLA:

Mlab_0764

MCHK:

MchiMG62_10120

MOU:	OU421_00695

MPL:	Mpal_1399 Mpal_1415 Mpal_2770

THB:	N186_00385

TCB:	TCARB_1157

» show all

Reference

Authors

Hoshino K.

Title

Organism producing isopropanol from acetone. V. Enzymological [studies] on the oxidation-reduction of Lactobacillus brevis var. hofuensis. [in Japanese].

Journal

Nippon Nogei Kagaku Kaishi 34:608-615 (1960)

Reference

Authors

Hoshino K, Udagawa K.

Title

Organism producing isopropanol from acetone. VI. Isopropanol dehydrogenase and alcohol dehydrogenase of Lactobacillus brevis var. hofuensis. [in Japanese].

Journal

Nippon Nogei Kagaku Kaishi 34:616-619 (1960)

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.80

IUBMB Enzyme Nomenclature:

1.1.1.80

ExPASy - ENZYME nomenclature database:

1.1.1.80

BRENDA, the Enzyme Database:

1.1.1.80

CAS:	37250-18-3

LinkDB

DBGET integrated database retrieval system