UY38142A - Uso de compuestos heteroarilo-triazol y heteroarilo-tetrazol como plaguicidas para la protección de plantas - Google Patents

Uso de compuestos heteroarilo-triazol y heteroarilo-tetrazol como plaguicidas para la protección de plantas

Info

Publication number
UY38142A
UY38142A UY38142A UY38142A UY38142A UY 38142 A UY38142 A UY 38142A UY 38142 A UY38142 A UY 38142A UY 38142 A UY38142 A UY 38142A UY 38142 A UY38142 A UY 38142A
Authority
UY
Uruguay
Prior art keywords
heteroaryl
triazole
protection
pesticides
plants
Prior art date
Application number
UY38142A
Other languages
English (en)
Inventor
Martin Füsslein Dr
Sebastian Horstmann Dr
Yolanda Cancho Grande Dr
Dr Peter Jeschke Prof
Elke Hellwege Dr
Marc Linka Dr
Ulrich Ebbinghaus-Kintscher Dr
Alexander Arlt Dr
Arunas Jonas Damijonaitis Dr
Hans-Georg Schwarz Dr
Kerstin Ilg Dr
Werner Hallenbach Dr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of UY38142A publication Critical patent/UY38142A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Uso de compuestos heteroarilo-triazol y heteroarilo-tetrazol como plaguicidas para la protección de plantas La presente invención se refiere al uso de compuestos heteroarilo-triazol y heteroarilo-tetrazol, al uso de formulaciones y composiciones que comprenden tales compuestos para controlar plagas animales, que incluyen artrópodos e insectos, para la protección de plantas.
UY38142A 2018-03-08 2019-03-08 Uso de compuestos heteroarilo-triazol y heteroarilo-tetrazol como plaguicidas para la protección de plantas UY38142A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18160736 2018-03-08
EP18185778 2018-07-26

Publications (1)

Publication Number Publication Date
UY38142A true UY38142A (es) 2019-10-01

Family

ID=65529718

Family Applications (1)

Application Number Title Priority Date Filing Date
UY38142A UY38142A (es) 2018-03-08 2019-03-08 Uso de compuestos heteroarilo-triazol y heteroarilo-tetrazol como plaguicidas para la protección de plantas

Country Status (13)

Country Link
US (1) US20200404919A1 (es)
EP (1) EP3761791A1 (es)
JP (1) JP2021516238A (es)
KR (1) KR20200129128A (es)
CN (1) CN111818801A (es)
AU (1) AU2019229521A1 (es)
BR (1) BR112020016946A2 (es)
CL (1) CL2020002323A1 (es)
MX (1) MX2020009320A (es)
PH (1) PH12020551407A1 (es)
TW (1) TW201940477A (es)
UY (1) UY38142A (es)
WO (1) WO2019170626A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY38184A (es) 2018-04-17 2019-10-31 Bayer Ag Compuestos heteroarilo-triazol y heteroarilo-tetrazol novedosos como plaguicidas
BR112020020712A2 (pt) * 2018-04-25 2021-01-12 Bayer Aktiengesellschaft Compostos de heteroaril-triazol e heteroaril-tetrazol como pesticidas
US20210068395A1 (en) * 2018-05-08 2021-03-11 Syngenta Crop Protection Ag Methods of applying one or more certain heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds to control damage on plants, propagation material thereof, and plant derived products
TW202019901A (zh) * 2018-09-13 2020-06-01 瑞士商先正達合夥公司 殺有害生物活性唑-醯胺化合物
TW202023386A (zh) * 2018-09-13 2020-07-01 瑞士商先正達合夥公司 殺有害生物活性唑-醯胺化合物
US20210403462A1 (en) * 2018-11-05 2021-12-30 Syngenta Participations Ag Pesticidally active azole-amide compounds
ES2972949T3 (es) * 2019-03-20 2024-06-17 Syngenta Crop Protection Ag Compuestos de azolamida plaguicidamente activos
WO2020193341A1 (en) * 2019-03-22 2020-10-01 Syngenta Crop Protection Ag N-[1-(5-bromo-2-pyrimidin-2-yl-1,2,4-triazol-3-yl)ethyl]-2-cyclopropyl-6-(trifluoromethyl)pyridine-4-carboxamide derivatives and related compounds as insecticides
UY38623A (es) * 2019-03-29 2020-10-30 Syngenta Crop Protection Ag Compuestos de diazina-amida activos como pesticidas
EP3725788A1 (en) 2019-04-15 2020-10-21 Bayer AG Novel heteroaryl-substituted aminoalkyl azole compounds as pesticides
AU2020317609A1 (en) 2019-07-23 2022-02-24 Bayer Aktiengesellschaft Novel heteroaryl-triazole compounds as pesticides
TW202118391A (zh) 2019-07-23 2021-05-16 德商拜耳廠股份有限公司 作為殺蟲劑之新穎雜芳基三唑化合物（二）
EP4041393A1 (en) 2019-10-09 2022-08-17 Bayer Aktiengesellschaft Novel heteroaryl-triazole compounds as pesticides
TW202128663A (zh) 2019-10-09 2021-08-01 德商拜耳廠股份有限公司 作為殺蟲劑之新穎雜芳基三唑化合物
WO2021068179A1 (en) * 2019-10-11 2021-04-15 Bayer Animal Health Gmbh Novel heteroaryl-substituted pyrazine derivatives as pesticides
TW202128650A (zh) * 2019-10-11 2021-08-01 德商拜耳動物保健有限公司 作為殺蟲劑之新穎的雜芳基取代之吡𠯤衍生物
TW202134226A (zh) * 2019-11-18 2021-09-16 德商拜耳廠股份有限公司 作為殺蟲劑之新穎雜芳基-三唑化合物
TW202136248A (zh) 2019-11-25 2021-10-01 德商拜耳廠股份有限公司 作為殺蟲劑之新穎雜芳基-三唑化合物
BR112022012130A2 (pt) 2019-12-18 2022-08-30 Intervet Int Bv Compostos antelmínticos compreendendo uma estrutura azaindólica
BR112022012126A2 (pt) 2019-12-18 2022-08-30 Intervet Int Bv Compostos antelmínticos compreendendo uma estrutura quinolínica
BR112022016400A2 (pt) 2020-02-18 2022-10-25 Bayer Ag Compostos inovadores de heteroaril-triazol como pesticidas
TW202208347A (zh) 2020-05-06 2022-03-01 德商拜耳廠股份有限公司 作為殺蟲劑之新穎雜芳基三唑化合物
EP3929189A1 (en) 2020-06-25 2021-12-29 Bayer Animal Health GmbH Novel heteroaryl-substituted pyrazine derivatives as pesticides
CA3203279A1 (en) 2020-12-11 2022-06-16 Intervet International B.V. Anthelmintic compounds comprising a thienopyridine structure
JP2024516278A (ja) 2021-05-06 2024-04-12 バイエル・アクチエンゲゼルシヤフト アルキルアミド置換環付加イミダゾール類及び殺虫剤としてのそれらの使用
MX2024002386A (es) 2021-08-25 2024-03-14 Bayer Ag Nuevos compuestos de pirazinil-triazol como pesticidas.
AU2022361189A1 (en) 2021-10-08 2024-03-14 Nihon Nohyaku Co., Ltd. Pyrimidinyl triazole compound or salt thereof, pest control agent containing said compound as active ingredient, and pest control method
EP4198033A1 (en) 2021-12-14 2023-06-21 Basf Se Heterocyclic compounds for the control of invertebrate pests
CN114487166B (zh) * 2021-12-31 2024-05-28 山东京博生物科技有限公司 一种2，6-二羟基-3-氰基-4-三氟甲基吡啶含量的检测方法
TW202413341A (zh) * 2022-09-23 2024-04-01 美商富曼西公司 吡唑醯胺殺昆蟲劑
EP4455137A1 (en) 2023-04-24 2024-10-30 Basf Se Pyrimidine compounds for the control of invertebrate pests
WO2024223373A1 (en) 2023-04-24 2024-10-31 Basf Se Pyrimidine compounds for the control of invertebrate pests

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63135364A (ja) * 1986-11-28 1988-06-07 Nissan Chem Ind Ltd アミド置換アセトニトリル誘導体、その製法および農園芸用殺菌剤
JPH10204066A (ja) * 1997-01-28 1998-08-04 Nippon Bayer Agrochem Kk １−フエニル−５−アニリノテトラゾール類及び農薬としてのその利用
EP1099695A1 (en) 1999-11-09 2001-05-16 Laboratoire Theramex S.A. 5-aryl-1H-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them
GB0213715D0 (en) 2002-06-14 2002-07-24 Syngenta Ltd Chemical compounds
TWI312272B (en) 2003-05-12 2009-07-21 Sumitomo Chemical Co Pyrimidine compound and pests controlling composition containing the same
GB0414438D0 (en) 2004-06-28 2004-07-28 Syngenta Participations Ag Chemical compounds
MX2007004710A (es) 2004-10-20 2007-06-14 Kumiai Chemical Industry Co Derivado de sulfuro de 3-triazolilfenilo e insecticida/acaricida/ nematicida que contiene el mismo como ingrediente activo.
ES2550398T3 (es) 2005-10-06 2015-11-06 Nippon Soda Co., Ltd. Compuestos de amina cíclica reticulados y agentes para el control de plagas
JP5268461B2 (ja) 2008-07-14 2013-08-21 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤
CN101337940B (zh) 2008-08-12 2012-05-02 国家农药创制工程技术研究中心 具杀虫活性的含氮杂环二氯烯丙醚类化合物
CN101337937B (zh) 2008-08-12 2010-12-22 国家农药创制工程技术研究中心 具有杀虫活性的n-苯基-5-取代氨基吡唑类化合物
CN101715774A (zh) 2008-10-09 2010-06-02 浙江化工科技集团有限公司 一个具有杀虫活性化合物制备及用途
EP2184273A1 (de) 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
GB0820344D0 (en) 2008-11-06 2008-12-17 Syngenta Ltd Herbicidal compositions
SI2369934T1 (sl) 2008-12-12 2014-07-31 Syngenta Participations Ag Spiroheterociklični N-oksipiperidini kot pesticidi
TWI487486B (zh) 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
WO2011085575A1 (zh) 2010-01-15 2011-07-21 江苏省农药研究所股份有限公司 邻杂环甲酰苯胺类化合物及其合成方法和应用
KR20130080485A (ko) 2010-05-31 2013-07-12 신젠타 파티서페이션즈 아게 작물 강화 방법
CN101967139B (zh) 2010-09-14 2013-06-05 中化蓝天集团有限公司 一种含一氟甲氧基吡唑的邻甲酰氨基苯甲酰胺类化合物、其合成方法及应用
BR112013014986A2 (pt) * 2010-12-17 2016-07-12 Syngenta Participations Ag compostos inseticidas
CN103842346A (zh) 2011-10-03 2014-06-04 先正达参股股份有限公司 作为杀虫化合物的异噁唑啉衍生物
WO2013050317A1 (en) 2011-10-03 2013-04-11 Syngenta Limited Polymorphs of an isoxazoline derivative
CN102391261A (zh) 2011-10-14 2012-03-28 上海交通大学 一种n-取代噁二嗪类化合物及其制备方法和应用
TWI566701B (zh) 2012-02-01 2017-01-21 日本農藥股份有限公司 芳烷氧基嘧啶衍生物及包含該衍生物作為有效成分的農園藝用殺蟲劑及其使用方法
WO2013144213A1 (en) 2012-03-30 2013-10-03 Basf Se N-substituted pyridinylidene compounds and derivatives for combating animal pests
EP2647626A1 (en) 2012-04-03 2013-10-09 Syngenta Participations AG. 1-Aza-spiro[4.5]dec-3-ene and 1,8-diaza-spiro[4.5]dec-3-ene derivatives as pesticides
NZ715920A (en) 2012-04-27 2016-07-29 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US9282739B2 (en) 2012-04-27 2016-03-15 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
CN103232431B (zh) 2013-01-25 2014-11-05 青岛科技大学 一种二卤代吡唑酰胺类化合物及其应用
CN103109816B (zh) 2013-01-25 2014-09-10 青岛科技大学 硫代苯甲酰胺类化合物及其应用
WO2014158644A1 (en) 2013-03-13 2014-10-02 Dow Agrosciences Llc Process for the preparation of triaryl rhamnose carbamates
JP6595985B2 (ja) 2013-05-23 2019-10-23 シンジェンタ パーティシペーションズ アーゲー タンク混合配合物
CN103265527B (zh) 2013-06-07 2014-08-13 江苏省农用激素工程技术研究中心有限公司 邻氨基苯甲酰胺化合物及其制备方法和应用
CN103524422B (zh) 2013-10-11 2015-05-27 中国农业科学院植物保护研究所 苯并咪唑衍生物及其制备方法和用途
JP2016539092A (ja) 2013-10-17 2016-12-15 ダウ アグロサイエンシィズ エルエルシー 有害生物防除性化合物の製造方法
EP3057429A4 (en) 2013-10-17 2017-08-09 Dow AgroSciences LLC Processes for the preparation of pesticidal compounds
AR108222A1 (es) * 2016-05-05 2018-08-01 Elanco Tiergesundheit Ag Compuestos heteroaril-1,2,4-triazol y heteroaril-tetrazol
KR20190075131A (ko) 2016-11-10 2019-06-28 뤄신 파마슈티컬 (상하이) 컴퍼니 리미티드 질소 함유 거대 고리계 화합물, 이의 제조 방법, 약물 조성물 및 용도

Also Published As

Publication number Publication date
US20200404919A1 (en) 2020-12-31
BR112020016946A2 (pt) 2020-12-15
CL2020002323A1 (es) 2021-04-30
TW201940477A (zh) 2019-10-16
KR20200129128A (ko) 2020-11-17
EP3761791A1 (en) 2021-01-13
AU2019229521A1 (en) 2020-09-03
JP2021516238A (ja) 2021-07-01
CN111818801A (zh) 2020-10-23
WO2019170626A1 (en) 2019-09-12
PH12020551407A1 (en) 2021-09-01
MX2020009320A (es) 2020-10-07

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