UY25101A1 - METHOD FOR THE TREATMENT OF DIABETES MELLITUS AND ASSOCIATED CONDITIONS - Google Patents

METHOD FOR THE TREATMENT OF DIABETES MELLITUS AND ASSOCIATED CONDITIONS

Info

Publication number
UY25101A1
UY25101A1 UY25101A UY25101A UY25101A1 UY 25101 A1 UY25101 A1 UY 25101A1 UY 25101 A UY25101 A UY 25101A UY 25101 A UY25101 A UY 25101A UY 25101 A1 UY25101 A1 UY 25101A1
Authority
UY
Uruguay
Prior art keywords
diabetes mellitus
insulin
mammal
alpha
treatment
Prior art date
Application number
UY25101A
Other languages
Spanish (es)
Inventor
Stephen Smith
Robin Buckingham
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of UY25101A1 publication Critical patent/UY25101A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Un método para el tratamiento de la diabetes mellitus y las condiciones asociadas con la diabetes mellitus en un mamífero, cuyo método comprende administrar una cantidad eficaz no tóxica y farmacéuticamente aceptable de un sensibilizador a insulina, un secretagogo de insulina y un agente antihiperglucemico inhibidor de alfa-glucosidasa, a un mamifero que necesita del mismo. En donde el secretagogo de insulina se selecciona entre glibenclamida, glipizida, glidlazida, glimepirida, clorpropamida, glibornurida, gliquidona, glisentida, glisolamida, glisoxepida, glicopiamida, glicidamida o repaglinida; el agente antihiperglucémico inhibidor de alfa-glucosidasa es acarbosa, emiglitato y miglitol; y el sensibilizador a insulina es 5-[4-[2-(N-metil-N-(2-piridil)amino)etoxi]-bencil]tiazolidin-2,4-diona.A method of treating diabetes mellitus and the conditions associated with diabetes mellitus in a mammal, the method of which comprises administering a non-toxic and pharmaceutically acceptable effective amount of an insulin sensitizer, an insulin secretagogue and an alpha-inhibitory antihyperglycemic agent. -glucosidase, to a mammal that needs it. Wherein the insulin secretagogue is selected from glibenclamide, glipizide, glidlazide, glimepiride, chlorpropamide, glibornuride, gliquidone, glisentide, glisolamide, glisoxepide, glycopiamide, glycid amide or repaglinide; the alpha-glucosidase inhibiting antihyperglycemic agent is acarbose, emiglitate and miglitol; and the insulin sensitizer is 5- [4- [2- (N-methyl-N- (2-pyridyl) amino) ethoxy] -benzyl] thiazolidin-2,4-dione.

UY25101A 1997-07-18 1998-07-17 METHOD FOR THE TREATMENT OF DIABETES MELLITUS AND ASSOCIATED CONDITIONS UY25101A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9715298A GB9715298D0 (en) 1997-07-18 1997-07-18 Novel method of treatment

Publications (1)

Publication Number Publication Date
UY25101A1 true UY25101A1 (en) 2000-12-29

Family

ID=10816170

Family Applications (1)

Application Number Title Priority Date Filing Date
UY25101A UY25101A1 (en) 1997-07-18 1998-07-17 METHOD FOR THE TREATMENT OF DIABETES MELLITUS AND ASSOCIATED CONDITIONS

Country Status (27)

Country Link
EP (1) EP1001784A1 (en)
JP (1) JP2001510160A (en)
KR (1) KR20010021952A (en)
CN (1) CN1263467A (en)
AP (1) AP2000001735A0 (en)
AR (2) AR016350A1 (en)
AU (1) AU8449098A (en)
BG (1) BG104062A (en)
BR (1) BR9810292A (en)
CA (1) CA2297133A1 (en)
CO (1) CO4940489A1 (en)
DZ (1) DZ2563A1 (en)
EA (1) EA200000140A1 (en)
GB (1) GB9715298D0 (en)
HU (1) HUP0003626A3 (en)
ID (1) ID23804A (en)
IL (1) IL133907A0 (en)
MA (1) MA24608A1 (en)
NO (1) NO20000230D0 (en)
OA (1) OA11312A (en)
PE (1) PE99499A1 (en)
PL (1) PL338140A1 (en)
SK (1) SK612000A3 (en)
TR (1) TR200000133T2 (en)
UY (1) UY25101A1 (en)
WO (1) WO1999003478A1 (en)
ZA (1) ZA986364B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
ATE372782T1 (en) 1999-06-21 2007-09-15 Lilly Co Eli SYNERGITIC USE OF THIAZOLIDINEDIONES AND GLUCAGONE-LIKE PEPTIDE-1 AND THEIR AGONISTS FOR THE TREATMENT OF NON-INSULIN DEPENDENT DIABETES
JP2003520226A (en) * 2000-01-21 2003-07-02 ノバルティス アクチエンゲゼルシャフト Combination comprising a dipeptidyl peptidase-IV inhibitor and an antidiabetic agent
WO2001062295A1 (en) * 2000-02-24 2001-08-30 Takeda Chemical Industries, Ltd. Drugs containing combined active ingredients
JP4917712B2 (en) * 2000-02-24 2012-04-18 武田薬品工業株式会社 Concomitant medication
EP1738751B1 (en) 2001-01-12 2011-05-11 Sun Pharma Advanced Research Company Ltd Spaced drug delivery system
FR2832930A1 (en) * 2001-12-03 2003-06-06 Lipha PHARMACEUTICAL COMPOSITION COMPRISING AN ALPHA-GLUCOSIDASE INHIBITOR AND A THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF FOR THE PREPARATION OF MEDICINES FOR TREATING DIABETES
CA2540225C (en) 2003-10-31 2012-03-06 Takeda Pharmaceutical Company Limited Solid preparation of pioglitazone, glimepiride and a polyoxyethylene sorbitan fatty acid ester
CN101103993B (en) * 2006-07-14 2011-03-30 北京华安佛医药研究中心有限公司 Hypoglycemic medicine composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2101866T3 (en) * 1991-08-26 1997-07-16 Upjohn Co LIQUID FOOD PRODUCT CONTAINING 3-GUANIDINOPROPIONIC ACID.
US5917052A (en) * 1994-09-28 1999-06-29 Shaman Pharmaceuticals, Inc. Hypoglycemic agent from cryptolepis
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes

Also Published As

Publication number Publication date
EA200000140A1 (en) 2000-06-26
CN1263467A (en) 2000-08-16
TR200000133T2 (en) 2000-09-21
SK612000A3 (en) 2000-07-11
IL133907A0 (en) 2001-04-30
JP2001510160A (en) 2001-07-31
AP2000001735A0 (en) 2000-01-16
DZ2563A1 (en) 2003-02-15
KR20010021952A (en) 2001-03-15
ZA986364B (en) 2000-01-17
CO4940489A1 (en) 2000-07-24
WO1999003478A1 (en) 1999-01-28
CA2297133A1 (en) 1999-01-28
NO20000230L (en) 2000-01-17
EP1001784A1 (en) 2000-05-24
NO20000230D0 (en) 2000-01-17
HUP0003626A2 (en) 2001-05-28
AR019724A2 (en) 2002-03-13
PL338140A1 (en) 2000-09-25
PE99499A1 (en) 1999-12-18
AU8449098A (en) 1999-02-10
BG104062A (en) 2000-11-30
MA24608A1 (en) 1999-04-01
BR9810292A (en) 2000-09-19
ID23804A (en) 2000-05-11
HUP0003626A3 (en) 2001-12-28
AR016350A1 (en) 2001-07-04
GB9715298D0 (en) 1997-09-24
OA11312A (en) 2003-10-24

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20121207