TR200100600T2 - İnsülinotropik peptitlerin kullanımı. - Google Patents

İnsülinotropik peptitlerin kullanımı.

Info

Publication number
TR200100600T2
TR200100600T2 TR2001/00600T TR200100600T TR200100600T2 TR 200100600 T2 TR200100600 T2 TR 200100600T2 TR 2001/00600 T TR2001/00600 T TR 2001/00600T TR 200100600 T TR200100600 T TR 200100600T TR 200100600 T2 TR200100600 T2 TR 200100600T2
Authority
TR
Turkey
Prior art keywords
insulinotropic peptides
insulinotropic
peptides
gluagon
pulmonaryly
Prior art date
Application number
TR2001/00600T
Other languages
English (en)
Inventor
Lee Hughes Benjamin
Keith Wolff Ronald
Lilly And Company Eli
Original Assignee
Lilly And Company Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26794577&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200100600(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly And Company Eli filed Critical Lilly And Company Eli
Publication of TR200100600T2 publication Critical patent/TR200100600T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Söz konusu bulus glükagon benzeri peptit-1 moleküllerinin diabet ve hiperglisemi hastaliginin tedavisinde pulmoner yoldan tatbik edilen bir ilacin imalatinda kullanilmasi ile ilgilidir.
TR2001/00600T 1998-08-28 1999-08-24 İnsülinotropik peptitlerin kullanımı. TR200100600T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9827398P 1998-08-28 1998-08-28
US10001298P 1998-09-11 1998-09-11

Publications (1)

Publication Number Publication Date
TR200100600T2 true TR200100600T2 (tr) 2001-07-23

Family

ID=26794577

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00600T TR200100600T2 (tr) 1998-08-28 1999-08-24 İnsülinotropik peptitlerin kullanımı.

Country Status (21)

Country Link
EP (1) EP0997151B1 (tr)
JP (1) JP2002523466A (tr)
KR (1) KR20010073033A (tr)
CN (1) CN1314818A (tr)
AR (1) AR022368A1 (tr)
AT (1) ATE347902T1 (tr)
AU (1) AU764371B2 (tr)
BR (1) BR9913284A (tr)
CA (1) CA2341454A1 (tr)
CO (1) CO5090908A1 (tr)
CZ (1) CZ2001690A3 (tr)
DE (1) DE69934380D1 (tr)
EA (1) EA200100289A1 (tr)
HR (1) HRP20010141A2 (tr)
HU (1) HUP0103369A3 (tr)
IL (1) IL141241A0 (tr)
NO (1) NO20010982L (tr)
PE (1) PE20001031A1 (tr)
PL (1) PL346317A1 (tr)
TR (1) TR200100600T2 (tr)
WO (1) WO2000012116A1 (tr)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AU2353701A (en) * 2000-01-11 2001-07-24 Novo Nordisk A/S Transepithelial delivery of glp-1 derivatives
US6540983B1 (en) * 2000-01-25 2003-04-01 Aeropharm Technology Incorporated Medical aerosol formulation
AU2001264789A1 (en) * 2000-06-08 2001-12-17 Eli Lilly And Company Protein powder for pulmonary delivery
NZ523693A (en) * 2000-07-10 2004-08-27 Chiron Corp Macrolide formulations for inhalation and methods of treatment of endobronchial infections
EP1542712A2 (en) * 2001-06-01 2005-06-22 Eli Lilly And Company Glp-1 formulations with protracted time action
IL160917A0 (en) 2001-10-18 2004-08-31 Bristol Myers Squibb Co Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
US7238671B2 (en) 2001-10-18 2007-07-03 Bristol-Myers Squibb Company Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
EP2277910A1 (en) 2001-12-21 2011-01-26 Human Genome Sciences, Inc. Albumin fusion proteins
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
CA2493478C (en) * 2002-08-01 2014-11-18 Mannkind Corporation Cell transport compositions and uses thereof
US8921311B2 (en) 2003-08-01 2014-12-30 Mannkind Corporation Method for treating hyperglycemia
CA2549582A1 (en) 2003-12-18 2005-06-30 Novo Nordisk A/S Novel glp-1 compounds
ES2385934T3 (es) 2004-08-20 2012-08-03 Mannkind Corporation Catálisis de la síntesis de dicetopiperazina.
BRPI0514293B1 (pt) 2004-08-23 2022-07-19 Mannkind Corporation Sistema microparticulado para distribuição de droga
KR100704447B1 (ko) * 2005-05-16 2007-04-09 정용현 3단계로 코팅되는 김치 유산균의 코팅방법 및 그로부터 제조된 코팅된 김치유산균 및 코팅된 김치 유산균이 함유된 조성물
BRPI0616071B8 (pt) 2005-09-14 2021-05-25 Mannkind Corp métodos de revestir uma micropartícula cristalina pré-formada em suspensão com um agente ativo
LT1965823T (lt) * 2005-11-04 2016-10-10 Glaxosmithkline Llc Hipoglikeminių agentų skyrimo būdai
ES2390286T3 (es) 2005-12-16 2012-11-08 Nektar Therapeutics Conjugados poliméricos de GLP-1
MX360812B (es) 2006-02-22 2018-11-16 Mannkind Corp Un método para mejorar las propiedades farmacéuticas de micropartículas que contienen dicetopiperazina y un agente activo.
PE20121528A1 (es) * 2006-09-13 2012-12-12 Smithkline Beecham Corp Metodos para administrar agentes hipoglucemiantes de larga duracion
WO2008132224A2 (en) 2007-04-30 2008-11-06 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
JP2009019027A (ja) * 2007-07-16 2009-01-29 Hanmi Pharmaceutical Co Ltd アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体
EP2211842B1 (en) * 2007-10-24 2015-08-12 MannKind Corporation An inhalable dry powder formulation comprising glp-1 for use in the treatment of hyperglycemia and diabetes by pulmonary administration
CA3086027C (en) 2008-06-13 2022-05-17 Mannkind Corporation A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2379100T3 (en) 2009-01-08 2014-12-01 Mannkind Corp Treatment of hyperglycemia with GLP-1
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
CN102647979B (zh) 2009-06-12 2015-03-04 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
JP6385673B2 (ja) 2010-06-21 2018-09-05 マンカインド コーポレイション 乾燥粉末薬物送達システム
KR101940832B1 (ko) 2011-04-01 2019-01-21 맨카인드 코포레이션 의약 카트리지용 블리스터 패키지
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US9233159B2 (en) 2011-10-24 2016-01-12 Mannkind Corporation Methods and compositions for treating pain
RU2650035C2 (ru) 2012-07-12 2018-04-06 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
MX2020009878A (es) 2013-07-18 2022-07-27 Mannkind Corp Composiciones farmaceuticas en polvo seco estables al calor y metodos.
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US11359267B2 (en) 2017-02-21 2022-06-14 Jfe Steel Corporation High-carbon hot-rolled steel sheet and method for manufacturing the same
GB201917723D0 (en) 2019-12-04 2020-01-15 Nv Rose Llc Stable liquid formulations of glucagon-like peptide 1 or analogues thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545618A (en) * 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
DK36492D0 (da) * 1992-03-19 1992-03-19 Novo Nordisk As Praeparat
NZ250844A (en) * 1993-04-07 1996-03-26 Pfizer Treatment of non-insulin dependant diabetes with peptides; composition
US5512549A (en) * 1994-10-18 1996-04-30 Eli Lilly And Company Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
UA72181C2 (uk) * 1996-08-30 2005-02-15 Ново Нордіск А/С Похідна глюкагоноподібного пептиду-1 (варіанти), фармацевтична композиція та спосіб одержання лікувального засобу (варіанти), спосіб лікування діабету (варіанти) і ожиріння
UA65549C2 (uk) * 1996-11-05 2004-04-15 Елі Ліллі Енд Компані Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
EP1019031A4 (en) * 1997-07-18 2003-02-05 Infimed Inc BIODEGRADABLE MACROMERS FOR THE REGULATED RELEASE OF BIOLOGICALLY ACTIVE SUBSTANCES

Also Published As

Publication number Publication date
CN1314818A (zh) 2001-09-26
DE69934380D1 (de) 2007-01-25
EP0997151A3 (en) 2000-09-20
AR022368A1 (es) 2002-09-04
EA200100289A1 (ru) 2001-10-22
CA2341454A1 (en) 2000-03-09
NO20010982D0 (no) 2001-02-27
EP0997151B1 (en) 2006-12-13
ATE347902T1 (de) 2007-01-15
NO20010982L (no) 2001-04-27
IL141241A0 (en) 2002-03-10
PL346317A1 (en) 2002-01-28
KR20010073033A (ko) 2001-07-31
HUP0103369A2 (hu) 2002-02-28
BR9913284A (pt) 2001-05-15
AU764371B2 (en) 2003-08-14
WO2000012116A1 (en) 2000-03-09
JP2002523466A (ja) 2002-07-30
EP0997151A2 (en) 2000-05-03
PE20001031A1 (es) 2000-10-12
AU5584199A (en) 2000-03-21
HUP0103369A3 (en) 2002-03-28
CZ2001690A3 (cs) 2002-04-17
CO5090908A1 (es) 2001-10-30
HRP20010141A2 (en) 2002-02-28

Similar Documents

Publication Publication Date Title
TR200100600T2 (tr) İnsülinotropik peptitlerin kullanımı.
EA200100939A1 (ru) Продолжительно действующие инсулинотропные пептиды
DE69531889D1 (de) Biologisch aktive Fragmente des Glucagon ähnlichen, insulinotropen Peptides
MXPA05007470A (es) Metodo para reducir la morbilidad y mortalidad cardiovascular en pacientes prediabeticos y pacientes con diabetes de tipo 2.
MXPA04003553A (es) Mimeticos del peptido-1 similares aglucagon humano y su uso en tratamiento de diabetes y condiciones relacionadas.
CY1110462T1 (el) Θεραπεια της ηπατικης ινωσης με αντισωματα εναντιον της ενσωματινης (ιντεγκρινης) αλφα v βητα 6
WO2006121860A3 (en) Glucagon-like peptide 1 (glp-1) receptor agonists and their pharmacological methods of use
DE122009000064I1 (de) Pharmazeutische Zubereitung enthaltend Pioglitazone und Glimepiride zur Verwendung in der Behandlungvon Diabetes.
PL393178A1 (pl) Heterogenne białko fuzyjne, kompozycja farmaceutyczna do leczenia pacjentów z cukrzycą insulino-niezależną i kompozycja farmaceutyczna do leczenia pacjentów z otyłością
ATE193541T1 (de) Insulinotropes hormon
EA200000652A1 (ru) Кристаллы глюкагоноподобного пептида 1
ATE466028T1 (de) N-terminal veränderte glp-1 abkömmlinge
ATE66614T1 (de) Insulinzubereitung fuer nicht-parenterale verabreichung.
ATE347562T1 (de) Insulin c-peptide
HUP9700806A2 (hu) Tianeptin-nátriumsó nyújtott felszabadulását biztosító, szájon át beadható mátrix tabletta és eljárás előállítására
TR200000134T2 (tr) Tiazolidinedion, ensülin salgılatıcısı ve biguanid ile diabetin (şeker hastalığının) tedavisi.
TR200503846T2 (tr) Değiştirilmiş salimli ensülin sensitizörü için fterkip ve kullanımı
BR0207704A (pt) Alfa interferon modificado com imunogenicidade reduzida
TR200000135T2 (tr) Tiazolidinedion ve sülfonilüre ile diabet tedavisi.
DK1675611T3 (da) Terapeutiske anvendelser for C-peptid
TR199901958T2 (tr) Infertiliteye karsi ve fertiliteyi artirmak için bir ilaç.
TR200102265T2 (tr) Anestezi düzenlemesi.
DE59805440D1 (de) Verwendung von lbp zur sepsistherapie
YU1901A (sh) Upotreba nab1 i nab2 u farmaciji
BR9703451C1 (pt) Composto natural para o tratamento de diabete ecâncer etc