NO147148C - Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater - Google Patents

Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater

Info

Publication number
NO147148C
NO147148C NO783442A NO783442A NO147148C NO 147148 C NO147148 C NO 147148C NO 783442 A NO783442 A NO 783442A NO 783442 A NO783442 A NO 783442A NO 147148 C NO147148 C NO 147148C
Authority
NO
Norway
Prior art keywords
phenyletanolamine
derivatives
preparation
new therapeutic
therapeutic active
Prior art date
Application number
NO783442A
Other languages
English (en)
Other versions
NO147148B (no
NO783442L (no
Inventor
Kazuo Iami
Kunihiro Niigata
Takashi Fujikura
Shinichi Hashimoto
Toichi Takenaka
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12203477A external-priority patent/JPS5473751A/ja
Priority claimed from JP12843677A external-priority patent/JPS5463048A/ja
Priority claimed from JP15535277A external-priority patent/JPS5495544A/ja
Priority claimed from JP7496478A external-priority patent/JPS552639A/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of NO783442L publication Critical patent/NO783442L/no
Publication of NO147148B publication Critical patent/NO147148B/no
Publication of NO147148C publication Critical patent/NO147148C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/34Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO783442A 1977-10-12 1978-10-11 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater NO147148C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP12203477A JPS5473751A (en) 1977-10-12 1977-10-12 Phenyl ethanolamine derivatives and their preparation
JP12843677A JPS5463048A (en) 1977-10-26 1977-10-26 Novel phenyl ethanolamine derivatives and their preparation
JP15535277A JPS5495544A (en) 1977-12-23 1977-12-23 Phenylethanolamine derivative and its preparation
JP7496478A JPS552639A (en) 1978-06-21 1978-06-21 Phenylethanolamine derivative and its preparation

Publications (3)

Publication Number Publication Date
NO783442L NO783442L (no) 1979-04-18
NO147148B NO147148B (no) 1982-11-01
NO147148C true NO147148C (no) 1983-02-09

Family

ID=27465764

Family Applications (1)

Application Number Title Priority Date Filing Date
NO783442A NO147148C (no) 1977-10-12 1978-10-11 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive fenyletanolaminderivater

Country Status (16)

Country Link
US (1) US4217305A (no)
AT (1) AT363457B (no)
AU (1) AU526715B2 (no)
CA (1) CA1147342A (no)
CH (1) CH639948A5 (no)
DE (1) DE2843016A1 (no)
DK (1) DK168484B1 (no)
ES (2) ES474149A1 (no)
FR (1) FR2405931A1 (no)
GB (1) GB2006772B (no)
GR (1) GR65337B (no)
IT (1) IT1160853B (no)
NO (1) NO147148C (no)
PT (1) PT68624A (no)
SE (1) SE448232B (no)
SU (2) SU982537A3 (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55124742A (en) * 1979-03-20 1980-09-26 Kyowa Hakko Kogyo Co Ltd Novel aminoalcohol derivative
US4206125A (en) * 1979-05-04 1980-06-03 Richardson-Merrell Inc. 5-[2-[(2,3-Dihydro-1,4-benzodioxan-2-ylmethyl)amino]-1-hydroxyethyl]-2-hydroxybenzoic acid derivatives
DD202692A5 (de) * 1979-12-04 1983-09-28 Ciba Geigy Verfahren zur herstellung neuer derivate des 2-amino-aethanols
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
US5391825A (en) * 1980-02-08 1995-02-21 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl substituted phenethylamine intermediates
US4558156A (en) * 1980-02-08 1985-12-10 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl-substituted phenethylamine derivatives
DE3128117A1 (de) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo Neue phenyl-aethylaminderivate, verfahren zu ihrer herstellung
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
EP0162404B1 (en) * 1984-05-15 1988-08-24 Seitetsu Kagaku Co., Ltd. Process for preparing 2-alkyl-5-haloacetylbenzenesulfonamide
US4678855A (en) * 1985-10-09 1987-07-07 Merck & Co., Inc. Substituted benzenesulfonamides
JPS62114952A (ja) * 1985-11-13 1987-05-26 Yamanouchi Pharmaceut Co Ltd 置換フエネチルアミン誘導体の製造法
EP0317206B1 (en) * 1987-11-13 1993-04-28 Glaxo Group Limited Phenethanolamine derivatives
KR100253515B1 (ko) * 1992-05-22 2000-05-01 요시다 쇼지 녹내장 치료용 의약 조성물
FR2737494B1 (fr) * 1995-08-04 1997-08-29 Synthelabo Derives de benzenesulfonamide, leur preparation et leur application en therapeutique
ES2208772T3 (es) * 1996-01-10 2004-06-16 Asahi Kasei Kabushiki Kaisha Nuevos compuestos triciclicos y compuestos farmaceuticos que contienen los mismos.
MXPA00010805A (es) * 1998-05-06 2002-05-08 Univ Duke Metodo para el tratamiento de sindromes de la vejiga y del tracto urinario inferior.
FR2791675B1 (fr) * 1999-03-30 2001-05-04 Synthelabo Derives de n-[2-(4-aminophenyl) ethyl] -2,3-dihydro-1,4- benzodioxinne-2-methanamine, leur preparation et leur application en therapeutique
US6835853B2 (en) 2001-10-31 2004-12-28 Synthon Bv Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith
DE60336485D1 (de) 2002-08-19 2011-05-05 Pfizer Kombinationstherapie gegen hyperproliferative erkrankungen
NZ543741A (en) 2003-05-30 2009-10-30 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as HMG-Co inhibitors
WO2005056521A1 (en) * 2003-12-09 2005-06-23 Cj Corporation Method of preparing optically pure phenethylamine derivatives
AU2005308575A1 (en) * 2004-11-23 2006-06-01 Warner-Lambert Company Llc 7-(2h-pyrazol-3-yl)-3, 5-dihyroxy-heptanoic acid derivatives as HMG Co-A reductase inhibitors for the treatment of lipidemia
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
JP2009514851A (ja) 2005-11-08 2009-04-09 ランバクシー ラボラトリーズ リミテッド (3r,5r)−7−[2−(4−フルオロフェニル)−5−イソプロピル−3−フェニル−4−[(4−ヒドロキシメチルフェニルアミノ)カルボニル]−ピロール−1−イル]−3,5−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
EP2026766A1 (en) 2006-05-17 2009-02-25 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US8465770B2 (en) * 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
CN102050766B (zh) * 2009-11-03 2013-08-07 安徽省新星药物开发有限责任公司 一种盐酸氨磺洛尔的合成方法
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN113574055B (zh) 2019-01-18 2024-07-23 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701808A (en) * 1967-12-21 1972-10-31 Allen & Hanburys Ltd Phenylethanolamines
GB1266058A (no) 1969-07-08 1972-03-08
GB1321701A (en) 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
US3711545A (en) * 1971-02-23 1973-01-16 Smith Kline French Lab Alpha-aminoalkyl-4-hydroxy-3-sulfamoylaminobenzyl alcohols
DE2115926C3 (de) * 1971-04-01 1978-05-03 C.H. Boehringer Sohn, 6507 Ingelheim 1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
US4034112A (en) * 1973-06-22 1977-07-05 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
US3860647A (en) * 1973-08-20 1975-01-14 Smithkline Corp {60 -Aminomethyl-4-hydroxy-3-sulfamyl-benzyl alcohols and 4-hydroxy-3-sulfamyl phenethylamines
GB1593651A (en) * 1977-02-03 1981-07-22 Allen & Hanburys Ltd Amides
DK31578A (da) * 1977-02-03 1978-08-04 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af benzenderivater

Also Published As

Publication number Publication date
AU526715B2 (en) 1983-01-27
US4217305A (en) 1980-08-12
SE7810613L (sv) 1979-04-13
ATA731778A (de) 1981-01-15
DK452178A (da) 1979-04-13
NO147148B (no) 1982-11-01
IT7869350A0 (it) 1978-10-11
FR2405931A1 (fr) 1979-05-11
DE2843016C2 (no) 1988-10-13
GB2006772A (en) 1979-05-10
SU982537A3 (ru) 1982-12-15
AT363457B (de) 1981-08-10
SU932982A3 (ru) 1982-05-30
AU4064278A (en) 1980-04-17
GR65337B (en) 1980-08-18
DK168484B1 (da) 1994-04-05
IT1160853B (it) 1987-03-11
PT68624A (en) 1978-11-01
FR2405931B1 (no) 1982-11-19
ES481549A1 (es) 1980-04-01
SE448232B (sv) 1987-02-02
CA1147342A (en) 1983-05-31
DE2843016A1 (de) 1979-04-26
CH639948A5 (de) 1983-12-15
GB2006772B (en) 1982-02-03
ES474149A1 (es) 1979-10-16
NO783442L (no) 1979-04-18

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