NO136574C - Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrimidinderivater. - Google Patents

Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrimidinderivater.

Info

Publication number
NO136574C
NO136574C NO3686/72A NO368672A NO136574C NO 136574 C NO136574 C NO 136574C NO 3686/72 A NO3686/72 A NO 3686/72A NO 368672 A NO368672 A NO 368672A NO 136574 C NO136574 C NO 136574C
Authority
NO
Norway
Prior art keywords
preparation
therapeutically active
pyrimidine derivatives
active pyrimidine
analogical procedure
Prior art date
Application number
NO3686/72A
Other languages
English (en)
Other versions
NO136574B (no
Inventor
Christopher Andrew Lipinski
John Gerritt Stam
Gerald George Deangelis
Hans-Jurgen Ernst Hess
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to NO763797A priority Critical patent/NO137596C/no
Publication of NO136574B publication Critical patent/NO136574B/no
Publication of NO136574C publication Critical patent/NO136574C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO3686/72A 1971-10-29 1972-10-13 Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrimidinderivater. NO136574C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO763797A NO137596C (no) 1971-10-29 1976-11-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive hydroksy-pyrimidinderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (2)

Publication Number Publication Date
NO136574B NO136574B (no) 1977-06-20
NO136574C true NO136574C (no) 1977-09-28

Family

ID=22715935

Family Applications (1)

Application Number Title Priority Date Filing Date
NO3686/72A NO136574C (no) 1971-10-29 1972-10-13 Analogifremgangsm}te for fremstilling av terapeutisk aktive pyrimidinderivater.

Country Status (25)

Country Link
JP (2) JPS5337870B2 (no)
AR (2) AR198798A1 (no)
AT (2) AT321308B (no)
AU (1) AU467600B2 (no)
BE (1) BE790125A (no)
CA (1) CA980778A (no)
CH (2) CH555832A (no)
DE (3) DE2248741C3 (no)
DK (1) DK131465B (no)
EG (1) EG11013A (no)
ES (2) ES407730A1 (no)
FI (1) FI55503C (no)
FR (1) FR2157865B1 (no)
GB (2) GB1377308A (no)
IE (1) IE37043B1 (no)
IL (2) IL40458A (no)
LU (1) LU66304A1 (no)
NL (1) NL166470C (no)
NO (1) NO136574C (no)
PH (2) PH10129A (no)
PL (2) PL84634B1 (no)
SE (2) SE393376B (no)
SU (2) SU498908A3 (no)
YU (2) YU35125B (no)
ZA (1) ZA727362B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (no) * 1979-04-17 1980-11-01
JPS5752409Y2 (no) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 p−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
ATE533488T1 (de) 2005-08-22 2011-12-15 Melior Pharmaceuticals I Inc Verfahren und formulierungen zur modulierung von lyn-kinaseaktivität und behandlung assoziierter erkrankungen
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
US20130158055A1 (en) 2010-05-28 2013-06-20 Andrew G. Reaume Prevention Of Pancreatic Beta Cell Degeneration
EP3609500B1 (en) 2017-04-10 2024-11-13 Melior Pharmaceuticals I, Inc. Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
DE2264374A1 (de) 1973-05-24
SE393376B (sv) 1977-05-09
PH10129A (en) 1976-09-02
NL166470C (nl) 1981-08-17
YU36295B (en) 1982-06-18
YU255172A (en) 1980-03-15
FR2157865B1 (no) 1975-10-31
PH11594A (en) 1978-03-31
DE2264374C3 (de) 1981-07-23
GB1377308A (en) 1974-12-11
JPS4852780A (no) 1973-07-24
AU467600B2 (en) 1975-12-04
IE37043B1 (en) 1977-04-27
NL166470B (nl) 1981-03-16
AU4722872A (en) 1974-04-04
DE2264657C2 (de) 1982-09-16
EG11013A (en) 1976-11-30
AR198798A1 (es) 1974-07-24
CH555832A (fr) 1974-11-15
CH549579A (fr) 1974-05-31
DK131465C (no) 1975-12-08
YU99179A (en) 1981-08-31
DE2248741A1 (de) 1973-05-03
SU505362A3 (ru) 1976-02-28
JPS5422995B2 (no) 1979-08-10
AT321308B (de) 1975-03-25
IL40458A0 (en) 1972-11-28
BE790125A (fr) 1973-04-16
SE7505279L (sv) 1975-05-06
SE397090B (sv) 1977-10-17
IL40458A (en) 1976-05-31
GB1377720A (en) 1974-12-18
DE2248741B2 (de) 1974-11-14
FI55503B (fi) 1979-04-30
ZA727362B (en) 1973-11-28
YU35125B (en) 1980-09-25
PL89852B1 (no) 1976-12-31
DE2264657A1 (de) 1974-06-20
DK131465B (da) 1975-07-21
DE2248741C3 (de) 1975-06-26
JPS53116386A (en) 1978-10-11
FR2157865A1 (no) 1973-06-08
ES436624A1 (es) 1977-02-01
CA980778A (en) 1975-12-30
JPS5337870B2 (no) 1978-10-12
IE37043L (en) 1973-04-29
NL7213959A (no) 1973-05-02
ES407730A1 (es) 1976-01-16
NO136574B (no) 1977-06-20
IL48790A0 (en) 1976-03-31
IL48790A (en) 1976-05-31
AT320656B (de) 1975-02-25
SU498908A3 (ru) 1976-01-05
PL84634B1 (no) 1976-04-30
FI55503C (fi) 1979-08-10
AR196263A1 (es) 1973-12-10
DE2264374B2 (de) 1980-08-07
LU66304A1 (no) 1973-05-03

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