JPS5356652A - Production of polyhalogenoo steroid - Google Patents

Production of polyhalogenoo steroid

Info

Publication number
JPS5356652A
JPS5356652A JP11619377A JP11619377A JPS5356652A JP S5356652 A JPS5356652 A JP S5356652A JP 11619377 A JP11619377 A JP 11619377A JP 11619377 A JP11619377 A JP 11619377A JP S5356652 A JPS5356652 A JP S5356652A
Authority
JP
Japan
Prior art keywords
polyhalogenoo
steroid
production
polyhalogenoo steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11619377A
Other languages
Japanese (ja)
Other versions
JPS6214557B2 (en
Inventor
Karufuoda Yarosurafu
Anneru Georugu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS5356652A publication Critical patent/JPS5356652A/en
Publication of JPS6214557B2 publication Critical patent/JPS6214557B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP11619377A 1976-09-29 1977-09-29 Production of polyhalogenoo steroid Granted JPS5356652A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75903A LU75903A1 (en) 1976-09-29 1976-09-29

Publications (2)

Publication Number Publication Date
JPS5356652A true JPS5356652A (en) 1978-05-23
JPS6214557B2 JPS6214557B2 (en) 1987-04-02

Family

ID=19728370

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11619377A Granted JPS5356652A (en) 1976-09-29 1977-09-29 Production of polyhalogenoo steroid

Country Status (24)

Country Link
JP (1) JPS5356652A (en)
AT (3) AT363197B (en)
AU (1) AU514200B2 (en)
BE (1) BE859120A (en)
CA (1) CA1101410A (en)
CH (9) CH624967A5 (en)
CY (1) CY1178A (en)
DD (1) DD133150A5 (en)
DE (1) DE2743069C2 (en)
DK (1) DK146017C (en)
ES (1) ES462763A1 (en)
FR (1) FR2366311A1 (en)
GB (1) GB1563638A (en)
HK (1) HK16683A (en)
HU (1) HU175218B (en)
IE (1) IE46047B1 (en)
IL (1) IL53012A (en)
KE (1) KE3258A (en)
LU (1) LU75903A1 (en)
MY (1) MY8400092A (en)
NL (1) NL7710089A (en)
SE (1) SE436751B (en)
SG (1) SG3383G (en)
ZA (1) ZA775800B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05501115A (en) * 1990-03-27 1993-03-04 シェリング・コーポレーション 9α-Hydroxy steroid dehydration method

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL187577C (en) * 1978-04-05 1991-11-18 Sibla Srl 3-ACETOXY-9BETA, 11BETA-EPOXY-PREGNA-1,3,5-TRIEN, PROCESS FOR THE PREPARATION THEREOF, AND PROCESS FOR THE PREPARATION OF 6-alpha-halogen-1,4-diene-3-ones.
DE3227312A1 (en) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen NEW 6.16 DIMETHYL CORTICOIDS, THEIR PRODUCTION AND USE
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
US7098328B2 (en) 2001-11-29 2006-08-29 Taro Pharmaceutical Industries Limited Method for the preparation of 6α-fluoro corticosteroids
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
HUE050603T2 (en) 2015-06-18 2020-12-28 Bausch Health Ireland Ltd Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis
US11311482B2 (en) 2017-05-12 2022-04-26 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898292A (en) * 1959-03-18 1962-06-06 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) * 1970-03-19 1972-02-22 Syntex Corp Preparation of 21-chloro steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05501115A (en) * 1990-03-27 1993-03-04 シェリング・コーポレーション 9α-Hydroxy steroid dehydration method

Also Published As

Publication number Publication date
ES462763A1 (en) 1978-05-16
CH631998A5 (en) 1982-09-15
ATA151379A (en) 1980-12-15
SG3383G (en) 1983-09-09
FR2366311A1 (en) 1978-04-28
BE859120A (en) 1978-03-28
ATA691077A (en) 1980-12-15
IE46047B1 (en) 1983-02-09
CA1101410A (en) 1981-05-19
CY1178A (en) 1983-06-10
CH632279A5 (en) 1982-09-30
CH625810A5 (en) 1981-10-15
JPS6214557B2 (en) 1987-04-02
GB1563638A (en) 1980-03-26
SE7706673L (en) 1978-03-30
HU175218B (en) 1980-06-28
IE46047L (en) 1978-03-29
KE3258A (en) 1983-03-04
SE436751B (en) 1985-01-21
DD133150A5 (en) 1978-12-13
DK256977A (en) 1978-03-30
AU514200B2 (en) 1981-01-29
IL53012A0 (en) 1977-11-30
CH625808A5 (en) 1981-10-15
DK146017C (en) 1983-10-24
ZA775800B (en) 1978-08-30
IL53012A (en) 1982-05-31
AU2914877A (en) 1979-04-05
NL7710089A (en) 1978-03-31
MY8400092A (en) 1984-12-31
DE2743069C2 (en) 1987-03-05
CH624967A5 (en) 1981-08-31
AT363197B (en) 1981-07-10
AT363202B (en) 1981-07-27
LU75903A1 (en) 1978-05-16
ATA151279A (en) 1980-12-15
CH632521A5 (en) 1982-10-15
CH631999A5 (en) 1982-09-15
HK16683A (en) 1983-05-27
CH632000A5 (en) 1982-09-15
CH625809A5 (en) 1981-10-15
AT363203B (en) 1981-07-27
DE2743069A1 (en) 1978-03-30
FR2366311B1 (en) 1982-12-03
DK146017B (en) 1983-05-24

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