ATA151279A - METHOD FOR PRODUCING NEW MULTIPLE HALOGENED STEROIDS - Google Patents

METHOD FOR PRODUCING NEW MULTIPLE HALOGENED STEROIDS

Info

Publication number: ATA151279A
Authority: AT; Austria
Prior art keywords: halogened; steroids; producing new; new multiple; producing
Prior art date: 1976-09-29

Application number

AT151279A

Other languages

German (de)

Other versions

AT363202B (en

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-09-29

Filing date

1979-02-28

Publication date

1980-12-15

1979-02-28 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1979-02-28 Priority to AT0151279A priority Critical patent/AT363202B/en

1980-12-15 Publication of ATA151279A publication Critical patent/ATA151279A/en

1981-07-27 Application granted granted Critical

1981-07-27 Publication of AT363202B publication Critical patent/AT363202B/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT0151279A 1976-09-29 1979-02-28 METHOD FOR PRODUCING NEW MULTIPLE HALOGENED STEROIDS AT363202B (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AT0151279A AT363202B (en)	1976-09-29	1979-02-28	METHOD FOR PRODUCING NEW MULTIPLE HALOGENED STEROIDS

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
LU75903A LU75903A1 (en)	1976-09-29	1976-09-29
AT0691077A AT363197B (en)	1976-09-29	1977-09-28	METHOD FOR PRODUCING NEW 9ALPHA, 21-DIHALOGEN-11BETA, 17ALPHA-DIHYDROXY-6ALPHA-FLUOR-16BETA-METHYL-PREGNA-1,4-DIEN-3,20-DION COMPOUNDS
AT0151279A AT363202B (en)	1976-09-29	1979-02-28	METHOD FOR PRODUCING NEW MULTIPLE HALOGENED STEROIDS

Publications (2)

Publication Number	Publication Date
ATA151279A true ATA151279A (en)	1980-12-15
AT363202B AT363202B (en)	1981-07-27

Family

ID=19728370

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT0691077A AT363197B (en)	1976-09-29	1977-09-28	METHOD FOR PRODUCING NEW 9ALPHA, 21-DIHALOGEN-11BETA, 17ALPHA-DIHYDROXY-6ALPHA-FLUOR-16BETA-METHYL-PREGNA-1,4-DIEN-3,20-DION COMPOUNDS
AT0151279A AT363202B (en)	1976-09-29	1979-02-28	METHOD FOR PRODUCING NEW MULTIPLE HALOGENED STEROIDS
AT0151379A AT363203B (en)	1976-09-29	1979-02-28	METHOD FOR PRODUCING NEW 9ALPHA, 21-

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT0691077A AT363197B (en)	1976-09-29	1977-09-28	METHOD FOR PRODUCING NEW 9ALPHA, 21-DIHALOGEN-11BETA, 17ALPHA-DIHYDROXY-6ALPHA-FLUOR-16BETA-METHYL-PREGNA-1,4-DIEN-3,20-DION COMPOUNDS

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT0151379A AT363203B (en)	1976-09-29	1979-02-28	METHOD FOR PRODUCING NEW 9ALPHA, 21-

Country Status (24)

Country	Link
JP (1)	JPS5356652A (en)
AT (3)	AT363197B (en)
AU (1)	AU514200B2 (en)
BE (1)	BE859120A (en)
CA (1)	CA1101410A (en)
CH (9)	CH624967A5 (en)
CY (1)	CY1178A (en)
DD (1)	DD133150A5 (en)
DE (1)	DE2743069C2 (en)
DK (1)	DK146017C (en)
ES (1)	ES462763A1 (en)
FR (1)	FR2366311A1 (en)
GB (1)	GB1563638A (en)
HK (1)	HK16683A (en)
HU (1)	HU175218B (en)
IE (1)	IE46047B1 (en)
IL (1)	IL53012A (en)
KE (1)	KE3258A (en)
LU (1)	LU75903A1 (en)
MY (1)	MY8400092A (en)
NL (1)	NL7710089A (en)
SE (1)	SE436751B (en)
SG (1)	SG3383G (en)
ZA (1)	ZA775800B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL187577C (en) *	1978-04-05	1991-11-18	Sibla Srl	3-ACETOXY-9BETA, 11BETA-EPOXY-PREGNA-1,3,5-TRIEN, PROCESS FOR THE PREPARATION THEREOF, AND PROCESS FOR THE PREPARATION OF 6-alpha-halogen-1,4-diene-3-ones.
DE3227312A1 (en) *	1982-07-19	1984-01-19	Schering AG, 1000 Berlin und 4709 Bergkamen	NEW 6.16 DIMETHYL CORTICOIDS, THEIR PRODUCTION AND USE
AU7556291A (en) *	1990-03-27	1991-10-21	Schering Corporation	Process for 9alpha-hydroxy steroid dehydration
US5972922A (en) *	1990-06-11	1999-10-26	Alcon Laboratories, Inc.	Steroids which inhibit angiogenesis
US7098328B2 (en)	2001-11-29	2006-08-29	Taro Pharmaceutical Industries Limited	Method for the preparation of 6α-fluoro corticosteroids
US8809307B2 (en)	2010-11-22	2014-08-19	Dow Pharmaceutical Sciences, Inc.	Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en)	2010-11-22	2024-04-16	Bausch Health Ireland Limited	Pharmaceutical formulations containing corticosteroids for topical administration
HUE050603T2 (en)	2015-06-18	2020-12-28	Bausch Health Ireland Ltd	Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis
US11311482B2 (en)	2017-05-12	2022-04-26	Bausch Health Us, Llc	Topical compositions and methods for treating skin diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB898292A (en) *	1959-03-18	1962-06-06	Upjohn Co	Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) *	1970-03-19	1972-02-22	Syntex Corp	Preparation of 21-chloro steroids
US3992422A (en) *	1975-08-14	1976-11-16	Schering Corporation	Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

1976
- 1976-09-29 LU LU75903A patent/LU75903A1/xx unknown
- 1976-12-09 CH CH1549976A patent/CH624967A5/en not_active IP Right Cessation
1977
- 1977-06-08 SE SE7706673A patent/SE436751B/en not_active IP Right Cessation
- 1977-06-09 DK DK256977A patent/DK146017C/en not_active IP Right Cessation
- 1977-09-14 NL NL7710089A patent/NL7710089A/en not_active Application Discontinuation
- 1977-09-24 DE DE2743069A patent/DE2743069C2/en not_active Expired
- 1977-09-26 CH CH1172177A patent/CH632279A5/en not_active IP Right Cessation
- 1977-09-27 DD DD7700201226A patent/DD133150A5/en unknown
- 1977-09-27 AU AU29148/77A patent/AU514200B2/en not_active Expired
- 1977-09-27 GB GB40131/77A patent/GB1563638A/en not_active Expired
- 1977-09-27 FR FR7729043A patent/FR2366311A1/en active Granted
- 1977-09-27 CY CY1178A patent/CY1178A/en unknown
- 1977-09-27 CA CA287,560A patent/CA1101410A/en not_active Expired
- 1977-09-28 ZA ZA00775800A patent/ZA775800B/en unknown
- 1977-09-28 IE IE1979/77A patent/IE46047B1/en not_active IP Right Cessation
- 1977-09-28 HU HU77CI1774A patent/HU175218B/en unknown
- 1977-09-28 IL IL53012A patent/IL53012A/en unknown
- 1977-09-28 AT AT0691077A patent/AT363197B/en not_active IP Right Cessation
- 1977-09-28 BE BE181243A patent/BE859120A/en not_active IP Right Cessation
- 1977-09-29 ES ES462763A patent/ES462763A1/en not_active Expired
- 1977-09-29 JP JP11619377A patent/JPS5356652A/en active Granted
1979
- 1979-02-28 AT AT0151279A patent/AT363202B/en not_active IP Right Cessation
- 1979-02-28 AT AT0151379A patent/AT363203B/en not_active IP Right Cessation
1980
- 1980-11-18 CH CH853780A patent/CH625808A5/en not_active IP Right Cessation
- 1980-11-18 CH CH853980A patent/CH625810A5/en not_active IP Right Cessation
- 1980-11-18 CH CH853880A patent/CH625809A5/en not_active IP Right Cessation
1981
- 1981-10-26 CH CH683281A patent/CH632000A5/en not_active IP Right Cessation
- 1981-10-26 CH CH683181A patent/CH631999A5/en not_active IP Right Cessation
- 1981-10-26 CH CH683081A patent/CH631998A5/en not_active IP Right Cessation
1982
- 1982-01-06 CH CH4682A patent/CH632521A5/en not_active IP Right Cessation
1983
- 1983-01-20 SG SG33/83A patent/SG3383G/en unknown
- 1983-01-21 KE KE3258A patent/KE3258A/en unknown
- 1983-05-19 HK HK166/83A patent/HK16683A/en not_active IP Right Cessation
1984
- 1984-12-30 MY MY92/84A patent/MY8400092A/en unknown

Also Published As

Publication number	Publication date
ES462763A1 (en)	1978-05-16
CH631998A5 (en)	1982-09-15
JPS5356652A (en)	1978-05-23
ATA151379A (en)	1980-12-15
SG3383G (en)	1983-09-09
FR2366311A1 (en)	1978-04-28
BE859120A (en)	1978-03-28
ATA691077A (en)	1980-12-15
IE46047B1 (en)	1983-02-09
CA1101410A (en)	1981-05-19
CY1178A (en)	1983-06-10
CH632279A5 (en)	1982-09-30
CH625810A5 (en)	1981-10-15
JPS6214557B2 (en)	1987-04-02
GB1563638A (en)	1980-03-26
SE7706673L (en)	1978-03-30
HU175218B (en)	1980-06-28
IE46047L (en)	1978-03-29
KE3258A (en)	1983-03-04
SE436751B (en)	1985-01-21
DD133150A5 (en)	1978-12-13
DK256977A (en)	1978-03-30
AU514200B2 (en)	1981-01-29
IL53012A0 (en)	1977-11-30
CH625808A5 (en)	1981-10-15
DK146017C (en)	1983-10-24
ZA775800B (en)	1978-08-30
IL53012A (en)	1982-05-31
AU2914877A (en)	1979-04-05
NL7710089A (en)	1978-03-31
MY8400092A (en)	1984-12-31
DE2743069C2 (en)	1987-03-05
CH624967A5 (en)	1981-08-31
AT363197B (en)	1981-07-10
AT363202B (en)	1981-07-27
LU75903A1 (en)	1978-05-16
CH632521A5 (en)	1982-10-15
CH631999A5 (en)	1982-09-15
HK16683A (en)	1983-05-27
CH632000A5 (en)	1982-09-15
CH625809A5 (en)	1981-10-15
AT363203B (en)	1981-07-27
DE2743069A1 (en)	1978-03-30
FR2366311B1 (en)	1982-12-03
DK146017B (en)	1983-05-24

Legal Events

Date	Code	Title	Description
1997-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties
1999-08-15	ELA	Expired due to lapse of time

Publication	Publication Date	Title
AT356827B (en)	1980-05-27	METHOD FOR PRODUCING NEW SPIROL ACTONES
AT358727B (en)	1980-09-25	METHOD FOR PRODUCING NEW CEPHALOS PORINANTIBIOTICS
AT356136B (en)	1980-04-10	METHOD FOR PRODUCING NEW SPIRO-HYDANTOINES
AT363478B (en)	1981-08-10	METHOD FOR PRODUCING NEW OXEPANDERIVATIVES
AT359187B (en)	1980-10-27	METHOD FOR PRODUCING NEW 7-BETA- (2- -OXYIMINO-2-ARYLACETAMIDO) -CEPHALOSPORINES
AT365611B (en)	1982-02-10	METHOD FOR PRODUCING NEW 17ALPHA- (3-R2-OXYPROPYL) -17BETA-R1-OXY-4-GONEN-ONES
AT358200B (en)	1980-08-25	METHOD FOR PRODUCING NEW STEROID ENOLESTERS
ATA151279A (en)	1980-12-15	METHOD FOR PRODUCING NEW MULTIPLE HALOGENED STEROIDS
AT360185B (en)	1980-12-29	METHOD FOR PRODUCING NEW DEHYDRODIGOPEPTIDES
AT353987B (en)	1979-12-10	METHOD FOR PRODUCING NEW SPIROOXAZOLIDE INDIONS
AT362786B (en)	1981-06-10	METHOD FOR PRODUCING NEW 1-ACYL-2-IMIDAZOLINES
AT358726B (en)	1980-09-25	METHOD FOR PRODUCING NEW CEPHALOS PORINANTIBIOTICS
AT360037B (en)	1980-12-10	METHOD FOR PRODUCING NEW SUBSTITUTED PHENYLGUANIDINES
AT351191B (en)	1979-07-10	METHOD FOR PRODUCING NEW D-HOMOSTEROIDS
AT355743B (en)	1980-03-25	METHOD FOR PRODUCING NEW CORTICOIDS
AT364364B (en)	1981-10-12	METHOD FOR PRODUCING NEW THIEPINES
AT375931B (en)	1984-09-25	METHOD FOR PRODUCING NEW AMINOALKYLFURANDERIVATIVES
AT343623B (en)	1978-06-12	METHOD FOR PRODUCING NEW N-ALKYL -4-NITRO-2-TRIFLUORMETHYLDIPHENYLAMINES
AT360646B (en)	1981-01-26	METHOD FOR PRODUCING NEW CEPHALOS PORINES
ATA175879A (en)	1980-02-15	METHOD FOR PRODUCING NEW ANTITUM ORGLYCOSIDES
ATA656076A (en)	1979-09-15	METHOD FOR PRODUCING NEW D-HOMOSTEROIDS
AT364367B (en)	1981-10-12	METHOD FOR PRODUCING NEW OXEPINES
AT355210B (en)	1980-02-25	METHOD FOR PRODUCING NEW 1-OXA DETHIACEPHALOSPORINES
AT355039B (en)	1980-02-11	METHOD FOR PRODUCING NEW EATHED HYDROXY-BENZIMIDAZOLONES, - BENZOXAZOLONES, -BENZOXAZINONS, - CHINA-ZOLINONES AND -CHINOXAZOLINONES
ATA566179A (en)	1981-12-15	METHOD FOR PRODUCING NEW N-HALOGENALKYL-N-NITROSOCARBAMOYLAZIDES