IL50874A - S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing them - Google Patents

S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing them

Info

Publication number: IL50874A
Authority: IL; Israel
Prior art keywords: alkyl; methylthioureido; methylguanidino; cyano; preparation
Prior art date: 1975-12-01

Application number

IL50874A

Other languages

English (en)

Other versions

IL50874A0 (en

Original Assignee

Smith Kline French Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-01

Filing date

1976-11-09

Publication date

1981-06-29

1976-11-09 Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab

1977-01-31 Publication of IL50874A0 publication Critical patent/IL50874A0/xx

1981-06-29 Publication of IL50874A publication Critical patent/IL50874A/xx

Links

125000000217 alkyl group Chemical group 0.000 title 2
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL50874A 1975-12-01 1976-11-09 S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing them IL50874A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB49248/75A GB1578219A (en)	1975-12-01	1975-12-01	Isothioureas

Publications (2)

Publication Number	Publication Date
IL50874A0 IL50874A0 (en)	1977-01-31
IL50874A true IL50874A (en)	1981-06-29

Family

ID=10451685

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL50874A IL50874A (en)	1975-12-01	1976-11-09	S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing them

Country Status (22)

Country	Link
US (2)	US4084001A (fr)
JP (1)	JPS5268128A (fr)
AT (1)	AT351559B (fr)
AU (1)	AU509662B2 (fr)
BE (1)	BE848909A (fr)
CA (1)	CA1083171A (fr)
CH (1)	CH624387A5 (fr)
DE (1)	DE2654515A1 (fr)
DK (1)	DK517476A (fr)
ES (1)	ES453801A1 (fr)
FI (1)	FI64800C (fr)
FR (1)	FR2375206A1 (fr)
GB (1)	GB1578219A (fr)
HU (1)	HU176328B (fr)
IE (1)	IE44358B1 (fr)
IL (1)	IL50874A (fr)
LU (1)	LU76285A1 (fr)
NL (1)	NL7613093A (fr)
NO (1)	NO142525C (fr)
PT (1)	PT65839B (fr)
SE (1)	SE7613382L (fr)
ZA (1)	ZA766778B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4158013A (en) *	1977-06-03	1979-06-12	Bristol-Myers Company	N-Cyano-N'-alkynyl-N"-2-mercaptoethylguanidines
US4157340A (en) *	1978-06-27	1979-06-05	Bristol-Meyers Company	N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives
PT69886A (en) *	1978-07-15	1979-08-01	Smith Kline French Lab	Process for preparing isoureas and isothioureas
DE3431923A1 (de) *	1984-08-30	1986-03-13	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von sulvonyliso(thio)harnstoffen
US7115620B2 (en)	2001-10-30	2006-10-03	Wyeth	1,3-disubstituted-2-thioxo-imidazolidine-4,5-diones as potassium channel openers
US7135492B2 (en) *	2001-10-30	2006-11-14	Wyeth	1,3-disubstituted-2- thioxo-imidazolidine-4,5-dione derivatives useful in the treatment of atherosclerosis
WO2022034121A1 (fr)	2020-08-11	2022-02-17	Université De Strasbourg	Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3669670A (en) *	1970-12-02	1972-06-13	Eastman Kodak Co	Photographic compositions containing bis-isothiuronium compounds as development activators and image stabilizers

1975
- 1975-12-01 GB GB49248/75A patent/GB1578219A/en not_active Expired
1976
- 1976-11-09 IL IL50874A patent/IL50874A/xx unknown
- 1976-11-11 ZA ZA766778A patent/ZA766778B/xx unknown
- 1976-11-15 PT PT65839A patent/PT65839B/pt unknown
- 1976-11-17 DK DK517476A patent/DK517476A/da not_active Application Discontinuation
- 1976-11-23 US US05/744,584 patent/US4084001A/en not_active Expired - Lifetime
- 1976-11-24 NL NL7613093A patent/NL7613093A/xx not_active Application Discontinuation
- 1976-11-25 JP JP51142102A patent/JPS5268128A/ja active Pending
- 1976-11-25 AT AT875176A patent/AT351559B/de not_active IP Right Cessation
- 1976-11-26 CH CH1493776A patent/CH624387A5/de not_active IP Right Cessation
- 1976-11-29 CA CA266,796A patent/CA1083171A/fr not_active Expired
- 1976-11-29 HU HU76SI1553A patent/HU176328B/hu unknown
- 1976-11-29 LU LU76285A patent/LU76285A1/xx unknown
- 1976-11-30 BE BE172841A patent/BE848909A/fr not_active IP Right Cessation
- 1976-11-30 ES ES453801A patent/ES453801A1/es not_active Expired
- 1976-11-30 SE SE7613382A patent/SE7613382L/xx not_active Application Discontinuation
- 1976-11-30 NO NO764084A patent/NO142525C/no unknown
- 1976-12-01 FI FI763458A patent/FI64800C/fi not_active IP Right Cessation
- 1976-12-01 AU AU20153/76A patent/AU509662B2/en not_active Expired
- 1976-12-01 FR FR7636265A patent/FR2375206A1/fr active Granted
- 1976-12-01 DE DE19762654515 patent/DE2654515A1/de not_active Withdrawn
- 1976-12-01 IE IE2635/76A patent/IE44358B1/en unknown
1978
- 1978-08-10 US US05/933,254 patent/USRE30457E/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA1083171A (fr)	1980-08-05
BE848909A (fr)	1977-05-31
PT65839B (en)	1978-05-15
NO142525C (no)	1980-09-03
FI64800B (fi)	1983-09-30
IL50874A0 (en)	1977-01-31
DE2654515A1 (de)	1977-06-02
USRE30457E (en)	1980-12-23
HU176328B (en)	1981-01-28
ES453801A1 (es)	1977-11-01
AT351559B (de)	1979-08-10
NO142525B (no)	1980-05-27
NL7613093A (nl)	1977-06-03
ZA766778B (en)	1977-10-26
FR2375206A1 (fr)	1978-07-21
PT65839A (en)	1976-12-01
ATA875176A (de)	1979-01-15
SE7613382L (sv)	1977-06-02
FR2375206B1 (fr)	1980-03-07
AU509662B2 (en)	1980-05-22
DK517476A (da)	1977-06-02
FI64800C (fi)	1984-01-10
IE44358L (en)	1977-06-01
CH624387A5 (fr)	1981-07-31
JPS5268128A (en)	1977-06-06
FI763458A (fr)	1977-06-02
AU2015376A (en)	1978-06-08
LU76285A1 (fr)	1977-05-20
GB1578219A (en)	1980-11-05
IE44358B1 (en)	1981-11-04
NO764084L (fr)	1977-06-02
US4084001A (en)	1978-04-11

Similar Documents

Publication	Publication Date	Title
DE2860900D1 (en)	1981-11-05	Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
DE2861318D1 (en)	1982-01-14	New derivatives of 4-phenyl-2-(2',2',2-trichlorethoxycarboxamido)-thiazole useful as medicaments, pharmaceutical compositions containing them and process for the preparation of these compounds
IL49405A (en)	1979-09-30	Substitutet 4,5,6,7-tetrahydrothieno(i8o-c)(or(o8i-c)pyridinol derivatives, their preparation and therapeutic compositions containing them
IL47394A0 (en)	1975-07-28	Heterocyclic guanidine derivatives,process for their preparation and pharmaceutical compositions containing them
GB2001624B (en)	1982-03-03	Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them
DE2861361D1 (en)	1982-01-28	1-n-acylated-4-o-glycosyl-6-o-glycosyl-1,3-diaminocyclitol derivatives, process for their preparation and pharmaceutical compositions containing them
DE2964209D1 (en)	1983-01-13	Spiro-furanohydantoin derivatives, process for their preparation and pharmaceutical compositions containing them
IL51857A (en)	1980-05-30	Bid-quaternary pyridinium-2-aldoxime salts,process for their preparation and pharmaceutical compositions containing them
IL54069A (en)	1982-01-31	14,15-dihydro-20,21-dinoreburnamenin-14-ol derivatives,process for preparing them and pharmaceutical compositions containing them
ZA79315B (en)	1980-09-24	Guanidine derivatives,processes for their production and pharmaceutical compositions containing them
IL49758A (en)	1978-12-17	10-( -benzoylpiperidin-1-yl)alkyl)-phenothiazine derivatives,their preparation and pharmaceutical compositions containing them
IL51001A (en)	1982-02-28	Unsymmetrical n,n'-dicarbamic acid sulfide derivatives,process for their preparation and insecticidal,miticidal and nematocidal compositions containing them
IL50874A (en)	1981-06-29	S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing them
IL52717A0 (en)	1977-10-31	Novel derivatives of 2-phenylamino-imidazoline-(2), their preparation and pharmaceutical compositions containing them
ZA772601B (en)	1978-09-27	New 1,4-benzodioxane derivatives,process for their preparation and pharmaceutical compositions
IL50230A (en)	1979-07-25	4,5-diphenyl-2-(substituted thio-sulfonyl)imidazole derivatives their preparation and pharmaceutical compositions containing them
DE2961394D1 (en)	1982-01-28	1-oxo-1h-pyrimido (6,1-b) benzothiazole derivatives, processes for their preparation and pharmaceutical compositions containing them
ZA784471B (en)	1979-08-29	Derivatives of 1,3-diphenoxypropane-2-on,process for their preparation,medicaments thereof,and their use as medicaments
IL54026A (en)	1983-06-15	Pharmaceutical compositions containing 1,3,5-triazine-2,6-dione derivatives,some novel compounds of this type and process for their preparation
ZA793682B (en)	1980-07-30	New piperidylbenzimidazolinone derivatives,processes for their preparation and pharmaceutical compositions containing them
DE2861767D1 (en)	1982-06-09	Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them
IL57533A (en)	1984-01-31	17alpha-acetylene derivatives of androst-4-ene,process for preparing them and pharmaceutical compositions containing them
IL54111A (en)	1981-07-31	3,6-disubstituted-1,2,4-triazine-5-one-derivatives,process for their preparation and pharmaceutical compositions containing them
IL55138A (en)	1982-05-31	Bis(nitrosoureido)-polyol derivatives,process for their preparation and pharmaceutical compositions containing them
IL54011A (en)	1981-05-20	1,3-bis(2-oxoazacycloalkyl-alkyl)urea and thiourea derivatives,their preparation and pharmaceutical compositions containing them