DE60335704D1 - Ein verfahren zur herstellung eines phenylalaninderivats und zwischenprodukte davon - Google Patents

Ein verfahren zur herstellung eines phenylalaninderivats und zwischenprodukte davon

Info

Publication number
DE60335704D1
DE60335704D1 DE60335704T DE60335704T DE60335704D1 DE 60335704 D1 DE60335704 D1 DE 60335704D1 DE 60335704 T DE60335704 T DE 60335704T DE 60335704 T DE60335704 T DE 60335704T DE 60335704 D1 DE60335704 D1 DE 60335704D1
Authority
DE
Germany
Prior art keywords
preparation
intermediate products
phenyl alanine
alanine derivative
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60335704T
Other languages
English (en)
Inventor
Isao Inoue
Toru Kuroda
Ryuzo Yoshioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Application granted granted Critical
Publication of DE60335704D1 publication Critical patent/DE60335704D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/82Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/87Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60335704T 2002-02-28 2003-02-27 Ein verfahren zur herstellung eines phenylalaninderivats und zwischenprodukte davon Expired - Lifetime DE60335704D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002052605 2002-02-28
PCT/JP2003/002181 WO2003072536A1 (en) 2002-02-28 2003-02-27 A process for preparing a phenylalanine derivative and intermediates thereof

Publications (1)

Publication Number Publication Date
DE60335704D1 true DE60335704D1 (de) 2011-02-24

Family

ID=27764341

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60335704T Expired - Lifetime DE60335704D1 (de) 2002-02-28 2003-02-27 Ein verfahren zur herstellung eines phenylalaninderivats und zwischenprodukte davon

Country Status (22)

Country Link
US (1) US7476758B2 (de)
EP (1) EP1478619B1 (de)
KR (1) KR100681224B1 (de)
CN (2) CN100480233C (de)
AR (1) AR038624A1 (de)
AT (1) ATE495147T1 (de)
AU (1) AU2003208618B2 (de)
BR (1) BR0308027A (de)
CA (1) CA2476022C (de)
DE (1) DE60335704D1 (de)
ES (1) ES2359302T3 (de)
HK (1) HK1069382A1 (de)
IL (1) IL163429A (de)
MX (1) MXPA04008359A (de)
MY (1) MY140707A (de)
NO (1) NO331001B1 (de)
NZ (1) NZ534957A (de)
PL (1) PL211046B1 (de)
RU (1) RU2280641C2 (de)
TW (1) TWI327996B (de)
WO (1) WO2003072536A1 (de)
ZA (1) ZA200406747B (de)

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US7208601B2 (en) * 2003-08-08 2007-04-24 Mjalli Adnan M M Aryl and heteroaryl compounds, compositions, and methods of use
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EP3873900A1 (de) 2018-10-30 2021-09-08 Gilead Sciences, Inc. Imidazopyridinderivate als alpha4beta7-integrininhibitoren
CR20210213A (es) 2018-10-30 2021-06-24 Gilead Sciences Inc Derivados de quinolina como inhibidores de la integrina alfa4beta7
WO2020092401A1 (en) 2018-10-30 2020-05-07 Gilead Sciences, Inc. COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN
EP3873897B1 (de) 2018-10-30 2024-08-14 Gilead Sciences, Inc. N-benzoyl-phenylalanin-derivate als alpha4beta7 integrin-inhibitoren zur behandlung von entzündlichen erkrankungen
CN114222730B (zh) 2019-08-14 2024-09-10 吉利德科学公司 用于抑制α4β7整合素的化合物

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Also Published As

Publication number Publication date
MY140707A (en) 2010-01-15
IL163429A (en) 2012-07-31
BR0308027A (pt) 2004-12-28
CN1817853A (zh) 2006-08-16
RU2280641C2 (ru) 2006-07-27
AU2003208618A1 (en) 2003-09-09
TW200303854A (en) 2003-09-16
ES2359302T3 (es) 2011-05-20
PL371386A1 (en) 2005-06-13
WO2003072536A1 (en) 2003-09-04
KR20040091665A (ko) 2004-10-28
AU2003208618B2 (en) 2008-06-19
AR038624A1 (es) 2005-01-19
EP1478619A1 (de) 2004-11-24
EP1478619B1 (de) 2011-01-12
NZ534957A (en) 2006-11-30
CA2476022C (en) 2008-07-15
NO20044087L (no) 2004-09-27
PL211046B1 (pl) 2012-04-30
US7476758B2 (en) 2009-01-13
HK1069382A1 (en) 2005-05-20
CN1646482A (zh) 2005-07-27
TWI327996B (en) 2010-08-01
KR100681224B1 (ko) 2007-02-09
ZA200406747B (en) 2005-08-31
CA2476022A1 (en) 2003-09-04
MXPA04008359A (es) 2004-11-26
CN100522930C (zh) 2009-08-05
NO331001B1 (no) 2011-09-05
CN100480233C (zh) 2009-04-22
RU2004128935A (ru) 2006-02-20
US20050165107A1 (en) 2005-07-28
ATE495147T1 (de) 2011-01-15

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