CN110122862A - A kind of special medicine purposes food and preparation method thereof reducing blood glucose - Google Patents
A kind of special medicine purposes food and preparation method thereof reducing blood glucose Download PDFInfo
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- CN110122862A CN110122862A CN201910465903.XA CN201910465903A CN110122862A CN 110122862 A CN110122862 A CN 110122862A CN 201910465903 A CN201910465903 A CN 201910465903A CN 110122862 A CN110122862 A CN 110122862A
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- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 description 1
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- 208000027418 Wounds and injury Diseases 0.000 description 1
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- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
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- 230000001684 chronic effect Effects 0.000 description 1
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- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
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- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 229940099596 manganese sulfate Drugs 0.000 description 1
- 239000011702 manganese sulphate Substances 0.000 description 1
- 235000007079 manganese sulphate Nutrition 0.000 description 1
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 description 1
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- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
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- 235000016709 nutrition Nutrition 0.000 description 1
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- 210000000496 pancreas Anatomy 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 229960000342 retinol acetate Drugs 0.000 description 1
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 description 1
- 235000019173 retinyl acetate Nutrition 0.000 description 1
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- 235000021003 saturated fats Nutrition 0.000 description 1
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- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 description 1
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- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019143 vitamin K2 Nutrition 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
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- 239000011670 zinc gluconate Substances 0.000 description 1
- 235000011478 zinc gluconate Nutrition 0.000 description 1
- 229960000306 zinc gluconate Drugs 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/185—Vegetable proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pediatric Medicine (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The application discloses a kind of special medicine purposes food, the special medicine purposes food includes 13 weight %-17 weight % of protein, 0.5 weight %-1.5 weight % of vitamin, 4 weight %-7 weight % of minerals, 30 weight %-40 weight % of carbohydrate, fat 8 weight %-1O weight %, dietary fiber 30 weight %-43 weight %, amino acid 1 weight %-1.5 weight % and 0.01 weight %-0.02 weight % of nucleotide.The special medicine purposes food of the application has the function of reducing blood glucose.
Description
Technical field
This application involves special medicine field of food more particularly to it is a kind of reduce blood glucose special medicine purposes food and its
Preparation method.
Background technique
Diabetes are one group of metabolic diseases characterized by hyperglycemia.Hyperglycemia be then due to defect of insulin secretion or
Its biological effect is impaired, or both have concurrently and cause.Long-standing hyperglycemia when diabetes leads to various tissues, especially
Eye, kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.Cause the cause of disease of diabetes complicated, relatively approve at present because
It is known as genetic cause, virus infection reason, autoimmunity reason, secondary reason of other diseases etc., but maximum reason is still
The problem of diet.As people's lives condition is become better and better, exquisite diet, high-carbonhydrate diet, high protein high fat diet, diet do not advised
Rule, drink, smoking etc. bad habits, in addition lack enough movement to consume taken in energy, energy surplus and cause diabetes.
Although treatment diabetes is mainly oral hypoglycemic agents perhaps insulin injection oral hypoglycemic agents or insulin injection energy at present
Blood glucose is controlled, but both has and leads to risk of hypoglycemia.If so in diabetes early stage by reasonable diet control with fortune
Kinetic energy reaches a certain level control blood glucose.If patient does not have to carry out the control of science on diet, even if oral hypoglycemic agents
Or insulin injection is also to have a significant impact to the stabilization of control blood glucose, the fluctuation of blood glucose also generates the health of patient very big
Influence, also greatly increase complication risk.
Summary of the invention
The problem of based on above physical presence, this application provides one kind to contain farnoquinone, and having reduces blood glucose
Spy doctor's food and preparation method.The spy cure food advantage be provided for hyperglycemic patients meet body metabolism needed for high-quality protein
Matter, multivitamin, minerals, amino acid, dietary fiber, fat, carbohydrate.The formula food can satisfy hyperglycemia
The daily nutritional need of patient, separation soyabean protein powder therein, soy protein concentrate powder are vegetable proteins, protein content compared with
Height, also containing the necessary amino acid of other human bodies, cholesterol is lower;Lactalbumin helps to reduce the weight of super severe one and postprandial
Glucose load reduces the risk that obesity-related disease occurs;High dietary-fiber can increase satiety, low saturated fat, short-chain fat
Acid is beneficial to the growth of intestinal beneficial bacterium;The intake of hypoglycemia patient carbohydrate can be reduced other unnecessary energy
Amount intake.Wherein vitamin C can protect lipid peroxidation with Scavenger of ROS (ROS) and active nitrogen (RNS), improve fasting blood
Sugar, glycosylated hemoglobin, total cholesterol and serum triglyceride level;Vitamin E can mitigate the excessively high caused injury of blood vessel of blood glucose,
Prevent and delay the generation of complication especially cardiovascular complication;Zinc can influence the synthesis of insulin, storage, secretion and
The integrality of structure adjusts insulin and acceptor levels, insulin-like effects carnitine, taurine and inositol is played in metabolism
It also contributes to mitigating hyperglycaemic diabetes symptom, reduces complication;Farnoquinone especially contained therein can enhance pancreas islet
Plain sensibility improves insulin resistance so as to which blood glucose is effectively reduced, and effective control of blood glucose can also subtract to greatest extent
The generation of few complication.
Specifically, this application provides a kind of special medicine purposes food, wherein the special medicine purposes food includes
13 weight %-17 weight % of protein, 0.5 weight %-1.5 weight % of vitamin, 4 weight %-7 weight % of minerals, carbon water
30 weight %-40 weight % of compound, fat 8 weight %-10 weight %, 30 weight %-43 weight % of dietary fiber, amino acid
0.01 weight %-0.02 weight % of 1 weight %-1.5 weight % and nucleotide.
In this application, the special medicine purposes food can also include the acceptable addition of special medicine purposes food
Agent;
The acceptable additive of special medicine purposes food can be selected from one of lubricant and wetting agent or two
Kind.
In this application, the special medicine purposes food can be oral preparation, preferably tablet or granule.
In this application, the special medicine purposes food can be dispersible tablet, buccal tablets or chewable tablet.
In this application, the protein can appoint in soyabean protein powder, walnut powder, wheat flour and lactalbumin
It is one or more of;
The soybean protein can be separation soyabean protein powder or soy protein concentrate powder;
The lactalbumin can be sepg whey albumen or whey protein concentrate.
In this application, the vitamin can be selected from vitamin A, B family vitamin, D family vitamin, choline, dimension
Any one of raw element E, vitamin C, D-Biotin, niacin, inositol, D-VB5 calcium, folic acid, farnoquinone and vitamin K1 or
It is more kinds of;
The vitamin A can be carotenoid precursors substance;
The B family vitamin can be before vitamin B1, vitamin B2, vitamin B6, vitamin 12, vitamin B1
Any one of body, vitamin B2 precursor, vitamin B precursor 6 and vitamin 12 precursor or more;
The D family vitamin can be selected from any one of D2, vitamine D3, calciferol precursor and precursor of vitamine D 3
Or more, preferred vitamin D3;
The farnoquinone can be selected from any one of chemical synthesis or natural fermented MK1 to MK14 or more,
It is preferred that natural fermented MK-7.
Farnoquinone, also referred to as methylnaphthoquinone (Menaquinone), are usually indicated with MK.It is made of one group of compound,
14 kinds of forms are shared, the difference is that side chain is different in size.MK is a series of containing 2-MNQ parent nucleus and C3 bands
The general designation of the terpenes side chain compound for the isoprene structures unit for thering is number not wait, according to the number of carbon on terpenes side chain
Mesh can be divided into K2 (10), K2 (20), K2 (35), K2 (40) etc., and K2 (35) is exactly to represent MK-7.
In some embodiments of the application, the special medicine purposes food may include 13 weight %- of protein
17 weight %, 0.5 weight %-1.5 weight % of vitamin, minerals 4 weight %-7 weight %, 30 weight %- of carbohydrate
40 weight %, 8 weight %-10 weight % of fat, 30 weight %-43 weight %, amino acid 1 weight %-1.5 weight of dietary fiber
Measure % and 0.01 weight %-0.02 weight % of nucleotide.The special medicine purposes food can also include special medicine purposes
The acceptable additive of food;The acceptable additive of special medicine purposes food can be in lubricant and wetting agent
One or two.The protein can selected from any one of soyabean protein powder, walnut powder, wheat flour and lactalbumin or
It is more kinds of.The vitamin can be selected from vitamin A, B family vitamin, D family vitamin, choline, vitamin E, vitamin
C, any one of D-Biotin, niacin, inositol, D-VB5 calcium, folic acid, farnoquinone and vitamin K1 or more;It is described
Vitamin A can be carotenoid precursors substance;The B family vitamin can be selected from vitamin B1, vitamin B2, vitamin
Any one of B6, vitamin 12, precursor of vitamin b 1, vitamin B2 precursor, vitamin B precursor 6 and vitamin 12 precursor or
It is more kinds of;The D family vitamin can be selected from any one of D2, vitamine D3, calciferol precursor and precursor of vitamine D 3
Or more, preferred vitamin D3;The farnoquinone can be selected from chemical synthesis or natural fermented MK1 appointing into MK14
One or more, preferably natural fermented MK-7.
In some embodiments of the application, the special medicine purposes food may include 13 weight %- of protein
17 weight %, 0.5 weight %-1.5 weight % of vitamin, minerals 4 weight %-7 weight %, 30 weight %- of carbohydrate
40 weight %, 8 weight %-10 weight % of fat, 30 weight %-43 weight %, amino acid 1 weight %-1.5 weight of dietary fiber
Measure % and 0.01 weight %-0.02 weight % of nucleotide.The special medicine purposes food can also include special medicine purposes
The acceptable additive of food;The acceptable additive of special medicine purposes food can be in lubricant and wetting agent
One or two.The protein can selected from any one of soyabean protein powder, walnut powder, wheat flour and lactalbumin or
It is more kinds of.The vitamin can be selected from vitamin A, B family vitamin, D family vitamin, choline, vitamin E, vitamin
C, any one of D-Biotin, niacin, inositol, D-VB5 calcium, folic acid, farnoquinone and vitamin K1 or more;It is described
Vitamin A can be carotenoid precursors substance;The B family vitamin can be selected from vitamin B1, vitamin B2, vitamin
Any one of B6, vitamin 12, precursor of vitamin b 1, vitamin B2 precursor, vitamin B precursor 6 and vitamin 12 precursor or
It is more kinds of;The D family vitamin is preferably vitamine D3;The farnoquinone is preferably natural fermented MK-7.
In this application, the minerals can selected from the minerals containing sodium ion, the minerals containing potassium ion, cupric from
Minerals, the minerals containing magnesium ion, the minerals containing iron ion, the minerals containing zinc ion, mineral with manganese ions of son
Any one of matter, the minerals of calcium ions, the minerals containing iodide ion, minerals containing plasma selenium or more.
In this application, the amino acid can be selected from L-lysine, L-Leu, l-Isoleucine, L-arginine, a left side
Revolve any or more of carnitine and taurine.
In this application, the nucleotide can be selected from inosine acid disodium, Sodium guanylate, born of the same parents' sweet acid disodium and uridylic acid
Any one of disodium or more.
In this application, the fat can be selected from vegetable oil, linoleic acid, linolenic acid, medium-chain fatty glyceride and length
Any one of chain fatty acid triglyceride or more.
In this application, the dietary fiber can be selected from one of soluble dietary fiber and insoluble diedairy fiber
Or two kinds;
The soluble dietary fiber can be selected from any one of bean gum, pectin, natural gum and oligofructose or more;
The insoluble diedairy fiber can be selected from any one of cellulose, hemicellulose and lignin or more.
In this application, the carbohydrate can be selected from any in lotus root starch, lotus nut starch and yam flour or wholemeal
Kind or more.
The application also provides the preparation method of the special medicine purposes food, and the preparation method includes:
Proteins,vitamins,minerals, carbohydrate, fat, dietary fiber and amino acid are mixed.
In this application, the preparation method includes:
By proteins,vitamins,minerals, carbohydrate, fat, dietary fiber and amino acid at 18 DEG C -22 of temperature
DEG C, it mixes and mixes under humidity 45%-65%, the acceptable additive of special medicine purposes food is then added, obtains the mouth
Formulation.
The application provides the special medicine purposes food also for reducing the purposes of blood glucose.
The special medicine purposes food of the application improves insulin resistance so as to which blood glucose is effectively reduced, and reduces complication
It generates.
Other features and advantage will illustrate in the following description, also, partly become from specification
It obtains it is clear that being understood and implementing the application.The purpose of the application and other advantages can by specification and
Specifically noted structure is achieved and obtained in claims.
Specific embodiment
It, hereinafter will be to embodiments herein for the purposes, technical schemes and advantages of the application are more clearly understood
It is described in detail.It should be noted that in the absence of conflict, the features in the embodiments and the embodiments of the present application can
With mutual any combination.
Embodiment
One, various raw materials needed for being weighed by formula rate,
It 1) include vitamin A retinol acetate (10%) 12mg, [B family vitamin (vitamin B1 by the vitamin
9mg, vitamin B2 9mg, vitamin B6 9mg, vitamin B12 (0.1%) 1.5mg], vitamine D3 (0.25%) 11mg, gallbladder
Alkali 2.4g, vitamin E 74mg, vitamin C 308mg, D-Biotin 2%7mg, niacin 19mg, inositol 2.4g, D-VB5 calcium
25mg, folic acid 0.72mg, farnoquinone (0.2%) 0.2g, the various vitamins of vitamin K1 0.25mg or more are first passed using equivalent
The method manual mixing of increasing obtains being uniformly mixed powder 1 after 60 mesh stainless steel mesh 3 times.
2) by the minerals sodium chloride 7.5g, potassium dihydrogen phosphate 8.5g, copper gluconate 18.6mg, magnesium sulfate 3g, lemon
Lemon acid ferrous iron 1.6g, zinc gluconate 350mg, manganese sulfate 16.8mg, calcium carbonate 7g, potassium iodide 0.3mg, Se-enriched yeast 0.25g
The above minerals first use the method manual mixing of equal increments, obtain being uniformly mixed powder 2 after 60 mesh stainless steel mesh 3 times.
3) amino acid be can be into L-lysine 0.8g, L-Leu 1.3g, l-Isoleucine 0.9g, L-arginine
0.8g, L-carnitine 1.0g, taurine 1g use the method manual mixing of equal increments with upper amino acid, stainless after 60 mesh
It obtains for steel sieve 3 times being uniformly mixed powder 3.
4) by the dietary fiber soluble dietary fiber: bean gum 18g, pectin 17g, gummy 16g, oligofructose 56g;No
Soluble dietary fiber: cellulose 19g, hemicellulose 20g, lignin 12g.The method manual mixing of equal increments is first used, then
60 mesh stainless steel mesh 3 times are crossed to obtain being uniformly mixed powder.
5) by the vegetable oil 6g of the fat, linoleic acid 8g, linolenic acid 10g, medium-chain fatty glyceride 10g, long-chain rouge
Vegetable oil, linoleic acid, linolenic acid in fatty acid glyceride 6g first use and equivalent 4) powder dilution, add medium chain fatty acid
Ester, long-chain fat acid glyceride are mixed, and obtain being uniformly mixed powder 4 after 60 mesh stainless steel mesh 3 times.
6) the carbohydrate lotus root starch 38g, lotus nut starch 40g, yam flour 50g, wholemeal 30g first use equal increments
Method manual mixing obtains being uniformly mixed powder 6 after 60 mesh stainless steel mesh 3 times.
It 7) include inosine acid disodium 30mg, Sodium guanylate 20mg, born of the same parents sweet acid disodium 10mg, uridylic acid by the nucleotide
Disodium 10mg first uses the method manual mixing of equal increments, obtains being uniformly mixed powder 7 after 60 mesh stainless steel mesh 3 times.
8) the soyabean protein powder 27g of the protein, walnut powder 15g, wheat flour 14g, PURE WHEY 12g are first adopted
With the method manual mixing of equal increments, obtain being uniformly mixed powder 8 after 60 mesh stainless steel mesh 3 times.
Above operating environment is completed in 100,000 grades of dust proof workshops, and 18-22 DEG C of temperature, humidity is 45-65%.
Two, the above powder 1-8 is uniformly mixed in being sequentially placed into GHL-300B efficient wet mixer-granulator, is added
Mouth is made in required (1-2% is based on weight of material) magnesium stearate or 10% starch slurry 10%-15% (by weight) of concentration
Formulation.
Three, the blood sugar decreasing effect of the application preparation.
It randomly selects 50 type-II diabetes to suffer from as volunteer and sign informed consent form, volunteer is randomly divided into two
Group, control group and treatment group, wherein control group totally 25, the age is 30 years old minimum, 60 years old maximum, average (45.5 ± 7.91) year,
Male 14, female 11.Treatment group totally 25, it is the age minimum 28 years old, 58 years old maximum, average (46.63 ± 7.68) year, male 15,
Female 10.The daily breakfast, lunch and dinner of control group are edible to carry out according to former mode, and treatment group daily three is given before the meal according to specific embodiment
The pulvis of the method preparation of middle embodiment 2, each 150g are reconstituted with 37-40 DEG C of the warm water of 300ml and are taken;Two groups of personnel
Before the meal and after the meal 5min, surveys its blood glucose in 0.5,1,2,3 hour respectively, is carried out continuously ten days, during experiment in two groups of personnel, dinner
Type is identical with amount, and the type and dosage of hypoglycemic medicine remain unchanged;Subsequent two groups of equal continual cures, with 90 days
It is as a treatment course, influence of the evaluation to postprandial blood sugar after a course for the treatment of.
Test result: the variation (x ± s) of each period blood glucose (mmol/l) of control group and treatment group
The blood glucose level of control group and treatment group before table 1 is treated
Group | On an empty stomach | Postprandial 5min | Postprandial 0.5h | Postprandial 1h | Postprandial 2h | Postprandial 3h |
Control group | 7.05±0.28 | 9.59±0.62 | 12.10±0.89 | 13.63±0.89 | 12.10±0.89 | 10.35±0.58 |
Treatment group | 7.12±0.27 | 9.53±0.38 | 11.30±0.63 | 10.36±0.70 | 10.36±0.59 | 9.65±0.68 |
After 2 one courses for the treatment of of table, the blood glucose level of control group and treatment group
Group | On an empty stomach | Postprandial 5min | Postprandial 0.5h | Postprandial 1h | Postprandial 2h | Postprandial 3h |
Control group | 7.12±0.32 | 9.28±0.32 | 11.80±0.45 | 13.31±0.74 | 11.60±0.25 | 10.15±0.53 |
Treatment group | 6.82±0.61 | 8.50±0.35 | 9.30±0.60 | 8.62±0.63 | 7.82±0.69 | 7.65±0.43 |
As can be seen from Table 1 and Table 2, before the treatment, blood glucose difference and little, warp of the control group with treatment group's each period
Cross a course for the treatment of for food and drink food after, the blood glucose value for the treatment of group's each period is all lower than control group, and without occur a mistake
High peak value.Illustrate that the special medicine purposes food of the application has the function of reducing blood glucose.
Although embodiment disclosed by the application is as above, the content only for ease of understanding the application and use
Embodiment is not limited to the application.Technical staff in any the application fields, is taken off not departing from the application
Under the premise of the spirit and scope of dew, any modification and variation, but the application can be carried out in the form and details of implementation
Scope of patent protection, still should be subject to the scope of the claims as defined in the appended claims.
Claims (15)
1. a kind of special medicine purposes food, wherein the special medicine purposes food includes 13 weight %-17 of protein weight
Measure %, 0.5 weight %-1.5 weight % of vitamin, minerals 4 weight %-7 weight %, 30 weight %-40 of carbohydrate weight
Measure %, fat 8 weight %-10 weight %, dietary fiber 30 weight %-43 weight %, amino acid 1 weight %-1.5 weight % with
0.01 weight %-0.02 weight % of nucleotide.
2. special medicine purposes food according to claim 1, the special medicine purposes food also includes special medicine
The acceptable additive of purposes food;
The acceptable additive of special medicine purposes food is selected from one or both of lubricant and wetting agent.
3. special medicine purposes food according to claim 1 or 2, wherein the special medicine purposes food is oral
Preparation, preferably tablet or granule.
4. special medicine purposes food according to claim 3, wherein the special medicine purposes food be dispersible tablet,
Buccal tablets or chewable tablet.
5. special medicine purposes food described in claim 1, wherein the protein is selected from soyabean protein powder, walnut powder, small
Any one of flour and lactalbumin or more;
The soybean protein is separation soyabean protein powder or soy protein concentrate powder;
The lactalbumin is sepg whey albumen or whey protein concentrate.
6. according to claim 1, special medicine purposes food described in any one of 2 and 5, wherein the vitamin is selected from dimension
Raw element A, B family vitamin, D family vitamin, choline, vitamin E, vitamin C, D-Biotin, niacin, inositol, D-VB5
Any one of calcium, folic acid, farnoquinone and vitamin K1 or more;
The vitamin A is carotenoid precursors substance;
The B family vitamin is selected from vitamin B1, vitamin B2, vitamin B6, vitamin 12, precursor of vitamin b 1, vitamin
Any one of B2 precursor, vitamin B precursor 6 and vitamin 12 precursor or more;
The D family vitamin is selected from any one of D2, vitamine D3, calciferol precursor and precursor of vitamine D 3 or more
Kind, preferred vitamin D3;
The farnoquinone is selected from any one of chemical synthesis or natural fermented MK1 to MK14 or more, preferably naturally
The MK-7 of fermentation.
7. according to claim 1, special medicine purposes food described in any one of 2 and 5, wherein the minerals, which are selected from, to be contained
The minerals of sodium ion, the minerals containing potassium ion, the minerals of copper ions, the minerals containing magnesium ion, containing iron ion
Minerals, the minerals containing zinc ion, minerals with manganese ions, calcium ions minerals, the minerals containing iodide ion, contain
Any one of minerals of plasma selenium or more.
8. according to claim 1, special medicine purposes food described in any one of 2 and 5, wherein the amino acid is selected from L-
Any one of lysine, L-Leu, l-Isoleucine, L-arginine, L-carnitine and taurine or more.
9. according to claim 1, special medicine purposes food described in any one of 2 and 5, wherein the nucleotide is selected from flesh
Any one of thuja acid disodium, Sodium guanylate, born of the same parents' sweet acid disodium and uridine monophosphate disodium or more.
10. according to claim 1, special medicine purposes food described in any one of 2 and 5, wherein the fat is selected from plant
Any one of oil, linoleic acid, linolenic acid, medium-chain fatty glyceride and long-chain fat acid glyceride or more.
11. according to claim 1, special medicine purposes food described in any one of 2 and 5, wherein the dietary fiber is selected from
One or both of soluble dietary fiber and insoluble diedairy fiber;
The soluble dietary fiber is selected from any one of bean gum, pectin, natural gum and oligofructose or more;It is described insoluble
Property dietary fiber be selected from any one of cellulose, hemicellulose and lignin or more.
12. according to claim 1, special medicine purposes food described in any one of 2 and 5, wherein the carbohydrate choosing
From lotus root starch, lotus nut starch and any one of yam flour or wholemeal or more.
13. the preparation method of special medicine purposes food described in any one of claims 1 to 12, the preparation method packet
It includes:
Proteins,vitamins,minerals, carbohydrate, fat, dietary fiber and amino acid are mixed.
14. preparation method according to claim 13, wherein the preparation method includes:
It is wet by proteins,vitamins,minerals, carbohydrate, fat, dietary fiber and amino acid at 18 DEG C -22 DEG C of temperature
It spends to mix under 45%-65% and mix, the acceptable additive of special medicine purposes food is then added, obtains the oral system
Agent.
15. special medicine purposes food according to any one of claim 1 to 12 is for reducing the purposes of blood glucose.
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CN103478527A (en) * | 2013-08-23 | 2014-01-01 | 内蒙古伊利实业集团股份有限公司 | Low-glycemic-index nutrient powder |
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