CN109945329A - Low temperature isolator air-conditioning system for the production of medicine enterprise - Google Patents
Low temperature isolator air-conditioning system for the production of medicine enterprise Download PDFInfo
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- CN109945329A CN109945329A CN201910345286.XA CN201910345286A CN109945329A CN 109945329 A CN109945329 A CN 109945329A CN 201910345286 A CN201910345286 A CN 201910345286A CN 109945329 A CN109945329 A CN 109945329A
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- low temperature
- surface cooling
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- 238000004378 air conditioning Methods 0.000 title claims abstract description 31
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 24
- 239000003814 drug Substances 0.000 title claims abstract description 22
- 238000001816 cooling Methods 0.000 claims abstract description 38
- 238000001914 filtration Methods 0.000 claims abstract description 21
- 230000000694 effects Effects 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 238000003303 reheating Methods 0.000 claims abstract description 8
- 238000010438 heat treatment Methods 0.000 claims description 14
- 230000008929 regeneration Effects 0.000 claims description 11
- 238000011069 regeneration method Methods 0.000 claims description 11
- 239000002274 desiccant Substances 0.000 claims description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- 230000000977 initiatory effect Effects 0.000 claims description 4
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 11
- 229940079593 drug Drugs 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 238000005265 energy consumption Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 239000003507 refrigerant Substances 0.000 description 2
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000007791 dehumidification Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000008821 health effect Effects 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
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- Central Air Conditioning (AREA)
Abstract
The invention discloses a kind of low temperature isolator air-conditioning systems for the production of medicine enterprise, the first effect fresh air section being successively arranged including Air conditioner box and in it, first surface cooling section, return air mixing section, medium efficiency filtration section, rotary wheel dehumidifying section, low temperature surface cooling section, reheating section, humidifier section, fan section, high-medium efficient wind outlet section, the first air-valve is provided between medium efficiency filtration section and rotary wheel dehumidifying section, the second air-valve is provided between rotary wheel dehumidifying section and low temperature surface cooling section, it is provided with bypass section parallel in rotary wheel dehumidifying section, third air-valve is provided between the bypass section and medium efficiency filtration section, the 4th air-valve is provided between bypass section and low temperature surface cooling section, first air-valve, second air-valve, third air-valve is connected with controller with the 4th air-valve, controller controls the first air-valve, second air-valve, the opening and closing of third air-valve and the 4th air-valve.Its remarkable result is: by plurality of operating modes harmony, segment body design rationality is high, and avoids defrost process.
Description
Technical field
The present invention relates to medicines to look forward to isolator air-conditioning technical field, and in particular to a kind of low temperature isolation for the production of medicine enterprise
Device air-conditioning system.
Background technique
Isolator has been exactly the equipment set of insulation blocking effect, as a kind of new drug technique production form, quilt
It is widely used in the production such as aseptic medicine.
But isolator producer can only cooperate with major well-known air-conditioning factory at present, groped by air-conditioning producer and provided
It is suitble to the Air-conditioner design scheme of isolator.Isolator air-conditioning system is sold while selling isolator.Due to air-conditioning producer technology
Proficiency is irregular, links up understanding with isolator producer and is not enough;And technical staff of isolator producer itself is to sky
Adjusting system lacks again understands in depth, certainly will will appear a series of problems: lack consideration of overall importance, when being adjusted to low temperature mode, every
Moisture condensation is easy from device surface;Defrosting system is complicated, and when low temperature mode is run, temperature and humidity fluctuation is big, and then influences drug quality;No
Can mutually it suit with production technology, isolator conditioning transition air type selecting;Coil pipe preparation is unreasonable, and valve frequently opens and closes;Air quantity tune in cabin
Section, pressure differential resetting are unreasonable etc..
Summary of the invention
In view of the deficiencies of the prior art, the object of the present invention is to provide a kind of low temperature isolator air-conditionings for the production of medicine enterprise
System, for the system by plurality of operating modes harmony, segment body design rationality is high, can effectively overcome existing in the prior art
Various defects.
In order to achieve the above objectives, The technical solution adopted by the invention is as follows:
A kind of low temperature isolator air-conditioning system for the production of medicine enterprise, including Air conditioner box, key are: the air-conditioning
It is cold that just effect fresh air section, the first surface cooling section, return air mixing section, medium efficiency filtration section, rotary wheel dehumidifying section, cryometer are successively arranged in cabinet
Section, reheating section, humidifier section, fan section, high-medium efficient wind outlet section, are arranged between the medium efficiency filtration section and rotary wheel dehumidifying section
There is the first air-valve, be provided with the second air-valve between the rotary wheel dehumidifying section and low temperature surface cooling section, in the rotary wheel dehumidifying section
Be provided with bypass section parallel, be provided with third air-valve between the bypass section and the medium efficiency filtration section, the bypass section with
Be provided with the 4th air-valve between low temperature surface cooling section, first air-valve, the second air-valve, third air-valve and the 4th air-valve with control
Device is connected, and the controller controls first air-valve, the second air-valve, according to the working condition of the rotary wheel dehumidifying section
The opening and closing of three air-valves and the 4th air-valve.
Further, the rotary wheel dehumidifying section includes desiccant wheel, upper layer air duct and lower layer air duct, and the desiccant wheel turns
It is dynamic to be set between upper layer air duct and lower layer air duct, and air flows on the contrary, in institute between the upper layer air duct and lower layer air duct
It states and is successively arranged regeneration fresh air area, the first filtering area, the second filtering area, heating zone, regeneration blower area in the air duct of upper layer.
Further, the heating zone and regeneration blower area are located at the two sides of the desiccant wheel.
Further, initial effect filtering section, heat pipe are also just disposed between effect fresh air section and the first surface cooling section described
Section, primary heating section.It can be gone out by the cooperation of the first surface cooling section, initial effect filtering section, hot pipe section, primary heating section outdoor new
Then the large quantity of moisture contained in wind is sent into rotary wheel dehumidifying section after mixing, to reduce the load of rotary wheel dehumidifying section, improve
The efficiency of rotary wheel dehumidifying section.The hot pipe section is for realizing the heat exchange between fresh air and air draft, to realize partial heat
Recycling, reduce primary heating section energy consumption.
Further, the second surface cooling section is additionally provided between the rotary wheel dehumidifying section and low temperature surface cooling section.
Further, high-medium efficient fillter section is additionally provided between the fan section and high-medium efficient wind outlet section.
Further, first surface cooling section and the second surface cooling section share same cold source, in order to concentrated controling management, drop
Low cost of implementation.
Further, the medium to circulate in the low temperature surface cooling section is low-temperature glycol.
Further, the blast pipe of the just effect fresh air section is provided with variable air rate cylinder, the high-medium efficient wind outlet section goes out
It is provided on air hose and determines air quantity cylinder.
Remarkable result of the invention is:
1, by plurality of operating modes harmony, segment body design rationality is high, improves low temperature cold source temperature, rotary wheel dehumidifying
Low temperature refrigerant temperature only need lower than air-supply point, and low temperature temperature-fall period is that the cold process no moisture of dry table is precipitated, health
Property is also more preferable;
2, moisture extra in air is directly extracted out with rotary wheel dehumidifying technology, so that the cold process of subsequent cryometer is dry
Table is cold to be gone out without elutriation, will not be avoided defrost process in coil pipe frosting, be avoided defrost energy consumption;
3, technique isolator has multi-state demand due to producing drug category difference, and the segment body combining form of design is almost
Enumerate low temperature mode, room temperature mode, the high temperature mode, the demand for sterilizing mode of isolator needs.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention;
Fig. 2 is the structural schematic diagram of the rotary wheel dehumidifying section 8.
Specific embodiment
Specific embodiment and working principle of the present invention will be described in further detail with reference to the accompanying drawing.
As shown in Figure 1, a kind of low temperature isolator air-conditioning system for the production of medicine enterprise, including Air conditioner box, the air-conditioning
It is mixed that just effect fresh air section 1, initial effect filtering section 2, hot pipe section 3, primary heating section 4, the first surface cooling section 5, return air are successively arranged in cabinet
Close section 6, medium efficiency filtration section 7, rotary wheel dehumidifying section 8, the second surface cooling section 9, low temperature surface cooling section 10, reheating section 11, humidifier section 12,
Fan section 13, high-medium efficient fillter section 14, high-medium efficient wind outlet section 15, medium efficiency filtration section 7, which is arranged, before rotary wheel dehumidifying section 8 can protect
Runner extends runner service life;
The first air returning valve 16 is provided between the medium efficiency filtration section 7 and rotary wheel dehumidifying section 8, in the rotary wheel dehumidifying section
8 and second are provided with the second air-valve 17 between surface cooling section 9, bypass section 18 are provided with parallel in the rotary wheel dehumidifying section 8, at this
It is provided with third air-valve 19 between bypass section 18 and the medium efficiency filtration section 7, between the bypass section 18 and the second surface cooling section 9
It is provided with the 4th air-valve 20, first air-valve 16, the second air-valve 17, third air-valve 19 and the 4th air-valve 20 are controlled with PLC
Device is connected, and the PLC controller controls first air-valve 16, second according to the working condition of the rotary wheel dehumidifying section 8
The opening and closing of air-valve 17, third air-valve 19 and the 4th air-valve 20, specific:
When isolator air-conditioning system, which needs to dehumidify, rotary wheel dehumidifying section 8 is needed to work, PLC controller controls the first air-valve
16 and second air-valve 17 open, third air-valve 19 and the 4th air-valve 20 closing;Isolator air-conditioning is not needed to pharmaceutical production at this time
The wind for having certain humidity is provided in live, but to pass through each surface cooling section after the fresh air of isolator air-conditioning and return air mixing,
Dehumidification treatments are carried out by rotary wheel dehumidifying section 8 after fresh air and return air mixing, are then sent after subsequent each segment body raw to drug
Produce scene;If requiring to room temperature (especially winter), to pass through reheating section 11 by the wind of surface cooling section
Certain heating is carried out, the gas come out from low temperature surface cooling section 10 reaches reheating section 11 and heated, that is to say, that runner
The wind that dehumidifying section 8 is discharged, which is sent after the second surface cooling section 9, low temperature surface cooling section 10 to reheating section 11, carries out heat exchange, thus
Wind in isolator air-conditioning is increased into certain temperature heel row and enters drug production scene.
When isolator air-conditioning system, which does not need dehumidifying, does not need the work of rotary wheel dehumidifying section 8, PLC controller controls third
Air-valve 19 and the 4th air-valve 20 are opened, and the first air-valve 16 is closed with third air-valve 17.In the case where weather is particularly suitable, isolation
Device air-conditioning does not need to handle the humidity of pharmaceutical production scene air, the operating mode in cooling, at this time fresh air and return
It is sent by bypass section 18 to subsequent segment body and is handled after wind mixing, finally sent to pharmaceutical production scene.
In the specific implementation, the different operating mode of purification air-conditioning is controlled and using PLC using PLC come control valve
Movement be the prior art, the present embodiment does not do excessive narration, all can be accordingly set inside air-conditioning in each segment body in the prior art
There is the basic module of surface air cooler, heater etc, the specific connection type between various components is the well-known technique of the industry, this
Example does not do specific description.
From figure 2 it can be seen that the rotary wheel dehumidifying section 8 includes desiccant wheel 8a, upper layer air duct 8b and lower layer air duct 8c,
The desiccant wheel 8a is rotatably dispose between upper layer air duct 8b and lower layer air duct 8c, and the upper layer air duct 8b and lower layer air duct
Air flow direction between 8c in the upper layer air duct 8b on the contrary, be successively arranged regeneration fresh air area 8d, the first filtering area 8e, the second mistake
Area 8f, heating zone 8g, regeneration blower area 8h are filtered, and the heating zone 8g and regeneration blower area 8h are located at the desiccant wheel
The two sides of 8a, the settable high-temp resisting high-humidity resisting type filter on the wind pipe of the upper layer air duct 8b.
Preferably, first surface cooling section 5 and the second surface cooling section 9 share same cold source, which is 7/12 DEG C of chilled water,
Partial moisture in air is removed by 7/12 DEG C of chilled water in the first surface cooling section 5, realizes water blocking and winter drying;The low temperature
The medium to circulate in surface cooling section 10 is low-temperature glycol;The heating zone, reheating section 11 and primary heating section 4 are all made of system
One heat source, the heat source are hot steam.
Referring to attached drawing 1, be provided with variable air rate cylinder 21 on the blast pipe of the just effect fresh air section 1, return air mixing section 6 into
It is provided on the discharge pipe of air hose and the high-medium efficient wind outlet section 15 and determines air quantity cylinder 22.
By rotary wheel dehumidifying section 8 and relevant each segment body combining form in the present embodiment, room temperature mode, high temperature are realized
Mode, low temperature return air mode plurality of operating modes harmony, segment body design rationality is high, not only realize in pharmaceutical production
The requirement of low temperature and low humidity, and almost enumerate the low temperature mode of isolator needs, room temperature mode, high temperature mode, disinfection mode
Demand, the low temperature refrigerant temperature during rotary wheel dehumidifying is only needed lower than air-supply point, and low temperature temperature-fall period is dry table
Cold process no moisture is precipitated, and wholesomeness is also more preferable;Moisture extra in air is directly extracted out with rotary wheel dehumidifying technology, so that after
The cold process of continuous cryometer is that dry table is cold to be gone out without elutriation, will not be avoided defrost process in coil pipe frosting, be avoided defrost energy
Consumption.
Claims (9)
1. a kind of low temperature isolator air-conditioning system for the production of medicine enterprise, including Air conditioner box, it is characterised in that: the air conditioner
It is cold that just effect fresh air section, the first surface cooling section, return air mixing section, medium efficiency filtration section, rotary wheel dehumidifying section, cryometer are successively arranged in case
Section, reheating section, humidifier section, fan section, high-medium efficient wind outlet section, are arranged between the medium efficiency filtration section and rotary wheel dehumidifying section
There is the first air-valve, be provided with the second air-valve between the rotary wheel dehumidifying section and low temperature surface cooling section, in the rotary wheel dehumidifying section
Be provided with bypass section parallel, be provided with third air-valve between the bypass section and the medium efficiency filtration section, the bypass section with
Be provided with the 4th air-valve between low temperature surface cooling section, first air-valve, the second air-valve, third air-valve and the 4th air-valve with control
Device is connected, and the controller controls first air-valve, the second air-valve, according to the working condition of the rotary wheel dehumidifying section
The opening and closing of three air-valves and the 4th air-valve.
2. the low temperature isolator air-conditioning system according to claim 1 for the production of medicine enterprise, it is characterised in that: the runner
The section that dehumidifies includes desiccant wheel, upper layer air duct and lower layer air duct, and the desiccant wheel is rotatably dispose in upper layer air duct and lower layer's wind
Between road, and air flows on the contrary, being successively arranged regeneration in the upper layer air duct between the upper layer air duct and lower layer air duct
Fresh air area, regeneration primarily efficient filter area, regeneration medium air filtration area, heating zone, regeneration blower area.
3. the low temperature isolator air-conditioning system according to claim 2 for the production of medicine enterprise, it is characterised in that: the heating
Area and regeneration blower area are located at the two sides of the desiccant wheel.
4. the low temperature isolator air-conditioning system according to claim 1 for the production of medicine enterprise, it is characterised in that: described first
Initial effect filtering section, hot pipe section, primary heating section are also disposed between effect fresh air section and the first surface cooling section.
5. the low temperature isolator air-conditioning system according to claim 1 for the production of medicine enterprise, it is characterised in that: at described turn
The second surface cooling section is additionally provided between wheel dehumidifying section and low temperature surface cooling section.
6. the low temperature isolator air-conditioning system according to claim 1 for the production of medicine enterprise, it is characterised in that: in the wind
High-medium efficient fillter section is additionally provided between machine section and high-medium efficient wind outlet section.
7. the low temperature isolator air-conditioning system according to claim 1 for the production of medicine enterprise, it is characterised in that: described first
Surface cooling section and the second surface cooling section share same cold source.
8. the low temperature isolator air-conditioning system according to claim 1 for the production of medicine enterprise, it is characterised in that: the low temperature
The medium to circulate in surface cooling section is low-temperature glycol.
9. the low temperature isolator air-conditioning system according to claim 1 for the production of medicine enterprise, it is characterised in that: described first
The blast pipe of effect fresh air section is provided with variable air rate cylinder, is provided on the discharge pipe of the high-medium efficient wind outlet section and determines air quantity cylinder.
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CN201910345286.XA CN109945329A (en) | 2019-04-26 | 2019-04-26 | Low temperature isolator air-conditioning system for the production of medicine enterprise |
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CN201910345286.XA CN109945329A (en) | 2019-04-26 | 2019-04-26 | Low temperature isolator air-conditioning system for the production of medicine enterprise |
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CN201910345286.XA Pending CN109945329A (en) | 2019-04-26 | 2019-04-26 | Low temperature isolator air-conditioning system for the production of medicine enterprise |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113144778A (en) * | 2021-05-14 | 2021-07-23 | 嵊州陌桑高科股份有限公司 | Air treatment system for culture room |
CN113197102A (en) * | 2021-05-14 | 2021-08-03 | 嵊州陌桑高科股份有限公司 | Air treatment device of air return system under roof conveying of breeding room |
CN113261540A (en) * | 2021-05-14 | 2021-08-17 | 嵊州陌桑高科股份有限公司 | Air environment control system that returns under breed room top |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113144778A (en) * | 2021-05-14 | 2021-07-23 | 嵊州陌桑高科股份有限公司 | Air treatment system for culture room |
CN113197102A (en) * | 2021-05-14 | 2021-08-03 | 嵊州陌桑高科股份有限公司 | Air treatment device of air return system under roof conveying of breeding room |
CN113261540A (en) * | 2021-05-14 | 2021-08-17 | 嵊州陌桑高科股份有限公司 | Air environment control system that returns under breed room top |
CN113144778B (en) * | 2021-05-14 | 2022-06-17 | 嵊州陌桑高科股份有限公司 | Air treatment system for culture room |
CN113261540B (en) * | 2021-05-14 | 2022-08-12 | 嵊州陌桑高科股份有限公司 | Air environment control system that returns under breed room top |
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Application publication date: 20190628 |