CN104488885B - A kind of Pesticidal combination preventing and treating sucking pest - Google Patents

Abstract

The invention discloses a kind of Pesticidal combination preventing and treating sucking pest, relate to technical field of pesticide.Described Pesticidal combination is made up of insecticidal active compound I and insecticidal active compound II; described insecticidal active compound I is Aminothiocarbonylbenzene, its chemistry entitled 3 bromine N [4 chlorine 2 methyl 6 (methylamino thioformyl) benzene] 1 (3 chloropyridine 2 base) 1H pyrazoles 5 Methanamide；Described insecticidal active compound II one in pymetrozine, Mobucin, Bassa, carbosulfan, Benfuracard micro, Aphox, Methomyl, meta-tolyl-N-methylcarbamate (MTMC).The compositions of the present invention has obvious potentiation relative to single dose, can effectively prevent and treat sucking pest, reduces the using dosage of pesticide, saves drug cost, makes up deficiency and the insect toleration to it of single dose simultaneously, improves insecticidal activity.

Description

A kind of Pesticidal combination preventing and treating sucking pest

Technical field

The present invention relates to technical field of pesticide, especially relate to the Pesticidal combination of two kinds of insecticidal active compound mixtures, It is specifically related to a kind of parasite killing group by Aminothiocarbonylbenzene with the preventing and treating sucking pest of insecticidal active compound mixture Compound.

Background technology

Chinese invention patent " thiobenzoyl aminated compounds and application thereof ", publication number CN103109816A, disclose The general structure 1 of thiobenzoyl aminated compounds is:

There is the thiobenzoyl aminated compounds of above-mentioned formula 1, not only lepidoptera pest is had high activity, and to thorn Suction insect (such as planthopper) also has beyond thought high activity, and this compounds has the most double controlling and acts on and comprehensive merit Energy.Applicant is chlorine according to the preferred R1 of formula 1, and R2 is methyl, with reference to the method synthesis in Chinese patent CN103109816A originally The insecticidal active compound I of invention, structural formula is as follows:

Though insecticidal active compound I is also the same with thiobenzoyl aminated compounds has a prominent insecticidal effect, but It can not fully meet insecticidal active compound to pest resistance and highly active requirement.Then multiple with other kind of insecticides Join the important means being to compensate its defect and increase range.As insecticidal active compound I makes for a long time in areal With, make crop pests that the raising of its resistance i.e. to be developed immunity to drugs, insecticidal activity declines.Therefore, in order to improve compound I Insecticidal activity, delay the service life of insecticidal active compound I, reduce the cost of novel pesticide exploitation, be badly in need of exploitation multiple with it The Pesticidal combination joined.

Up to now, this compounds is not the most shown in the report of the patent with other pesticide compositionals.

Summary of the invention

It is an object of the invention to: for the problem of above-mentioned existence, it is provided that a kind of parasite killing preventing and treating sucking pest Compositions and preparation thereof, this Pesticidal combination has obvious potentiation relative to single dose, can effectively prevent and treat sucking mouth parts Insect, reduces the using dosage of pesticide, saves drug cost, makes up deficiency and the insect toleration to it of single dose simultaneously, Improving insecticidal activity, insecticidal spectrum is more extensive.

For realizing above-mentioned purpose, technical scheme:

A kind of Pesticidal combination preventing and treating sucking pest, described Pesticidal combination by insecticidal active compound I and Insecticidal active compound II forms, and described insecticidal active compound I is Aminothiocarbonylbenzene, and its chemical name is 3-bromo-N-[4- Chloro-2-methyl-6-(methylamino thioformyl) benzene]-1-(3-chloropyridine-2-base)-1H-pyrazoles-5-Methanamide；Described parasite killing Reactive compound II is pymetrozine or carbamate insecticides.

In the presence of in Pesticidal combination of the present invention, reactive compound is with specified weight ratio, syneryistic effect highly significant. Preferably, the weight ratio of described insecticidal active compound I and insecticidal active compound II is 1:40～40:1.

It is further preferred that the weight ratio of described insecticidal active compound I and insecticidal active compound II is 1:30～30: 1。

In the present invention, the structural formula of above-mentioned Aminothiocarbonylbenzene is as follows:

The carbamate insecticides mentioned in the present invention, is all pesticide species that is known and that be disclosed, preferably is selected from different One in third prestige, Bassa, carbosulfan, Benfuracard micro, Aphox, Methomyl, meta-tolyl-N-methylcarbamate (MTMC).

Pymetrozine CAS No.:123312-89-0

Mobucin CAS No.:2631-40-5

Bassa CAS No.:3766-81-2

Carbosulfan CAS No.:55285-14-8

Benfuracard micro CAS No.:82560-54-1

Aphox CAS No.:23103-98-2

Methomyl CAS No.:16752-77-5

Meta-tolyl-N-methylcarbamate (MTMC) CAS No.:1129-41-5

The present invention also provides for a kind of insecticide, including above-mentioned a kind of Pesticidal combination preventing and treating sucking pest and Adjuvant forms, and in order to ensure that insecticide has more preferable insecticidal effect, as preferably, described Pesticidal combination accounts for described insecticide The 1%～90% of gross weight.

It is further preferred that described Pesticidal combination accounts for the 20%～60% of described insecticidal total weight.

It is highly preferred that described Pesticidal combination accounts for the 20%～40% of described insecticidal total weight.

Above-mentioned adjuvant is the mixture of a kind of and auxiliary agent in filler or solvent, is generally used for any load of composition pesticide Body and auxiliary agent all can use.

The available solvent of the present invention includes Ketohexamethylene, trimethylbenzene, methyl oleate, dimethylformamide, N-methyl pyrrole One or more in pyrrolidone, vegetable oil.

Filler includes Kaolin, Pulvis Talci, white carbon, precipitated calcium carbonate, kieselguhr, bentonite, pulls open powder, carbamide, corruption One or more in phytic acid.

Auxiliary agent of the present invention can according to different dosage form require to include emulsifying agent, wetting agent, dispersant, defoamer, Thickening agent, disintegrating agent, binding agent and antifreezing agent, it is also possible to include other functional aids that the industry is conventional as required.

Emulsifying agent, wetting agent or dispersant include tallow ethyoxyl ammonium salt, acyl group glutamate, phenolsulfonic acid condensation substance Sodium salt, methyl naphthalene sulfonate formaldehyde condensate, alkylnaphthalene sulfonate, sodium metnylene bis-naphthalene sulfonate, maleic-acrylic acid homopolymer Sodium salt, polymeric polycarboxylic acid salt, fatty alcohol polyoxyethylene ether sulfate, sodium lignin sulfonate, SOPA-270, tallow ethyoxyl Amine salt, dioctyl sodium sulphosuccinate salt, EO/PO block polyether, alkylnaphthalene sulfonate acrylate homopolymer sodium salt, methylene two Sodium naphthalene sulfonate, phenethyl phenol polyethenoxy ether, calcium dodecyl benzene sulfonate, agriculture breast 600#, lauryl alcohol polyethylene glycol oxide base ether, fat Alcohol ethyl oxide, acrylate homopolymer sodium salt, sulfomethylated lignin ester sodium, alkylphenol polyoxyethylene, NPE, Fatty alcohol-polyoxyethylene ether, lignosulfonates, methyl naphthalene sulfonic acid sodium, naphthalene sulfonate, sodium lauryl sulphate, polycarboxylate, One in Negel, naphthalene sulfonic acid condensate sodium salt, calcium lignosulfonate, alkyl benzene calcium sulfonate, TERWET-1007 or Several.

Thickening agent includes one or more in xanthan gum, Magnesiumaluminumsilicate, polyvinyl alcohol.

Antifreezing agent includes one or more in glycerol, propylene glycol, ethylene glycol, carbamide, isopropanol.Defoamer includes Machine silicon or polyethers.Preservative includes one or both in butyl p-hydroxybenzoate, Phenylsalicylate.Stabilizer includes epoxy Soybean oil, starch sodium octenyl succinate, triphenyl phosphite, epoxychloropropane.Disintegrating agent includes sodium sulfate, sodium chloride, sulfur Acid ammonium.Binding agent includes one or more in xanthan gum, polyvinyl alcohol, starch, methylcellulose, sodium carboxymethyl cellulose.

According to different use demands, the dosage form of the insecticide that the present invention provides can be multiple dosage form.In the present invention, The dosage form of insecticide is wettable powder, water dispersible granules, cream, aqueous emulsion, suspending agent.

The Pesticidal combination of the present invention and insecticide can be used by commonsense method, as spraying stem and leaf processes, it is possible to soil Processing, such as solid root spreads fertilizer over the fields or liquid pouring root, moreover it is possible to dresses seed, soak seed or seed pelleting use.

It addition, the present invention also provides for described Pesticidal combination and insecticide answering in sucking pest prevents and treats With.The present invention especially has specially good effect to planthopper, thrips, aphid, red spider.

The following beneficial effect that the present invention has relative to prior art:

1, the compositions of the present invention has obvious potentiation compared with single dose, and Toxicity Determination result shows, right Sucking pest has significant synergistic function, especially prevent and treat planthopper, aphid limit ratio range in, potentiation is common Poison coefficient (CTC) is more than 120.

2, the preventive effect of the parasite killing of the Pesticidal combination of the present invention and insecticide is high, and consumption is few, can reduce drug cost, And alleviate pesticide to ecological destruction.

Detailed description of the invention:

In order to make the purpose of the present invention, technical scheme and advantage clearer, present invention specific examples below Illustrating with example, described embodiment is to preferably explain the present invention rather than the limit to scope System, all based on any amendment made in basic thought of the present invention and principle and variation, broadly fall into what the present invention was claimed Scope.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.In these embodiments, unless otherwise indicated Outward, all percentage ratios are all weight percentage.Aminothiocarbonylbenzene is synthesized by laboratory, and other medicaments are commercial, except as otherwise Outside explanation, all percentage ratios are all weight percentage.

One, formulation Example:

Following for embodiments of the invention are described, it is reactive compound I (the bromo-N-of 3-[4-chloro-2-methyl-6-(first ammonia Base thioformyl) benzene]-1-(3-chloropyridine-2-base)-1H-pyrazoles-5-Methanamide) and hereinafter referred to as Aminothiocarbonylbenzene with kill Worm reactive compound II is with the compositions of specific blend composition of proportions.

(1) preparation of suspending agent

Embodiment 1:33% Aminothiocarbonylbenzene pymetrozine suspension agent (10:1)

By 33% reactive compound (30% Aminothiocarbonylbenzene and the compositions of 3% pymetrozine), alkylnaphthalene sulfonate 2%, fatty alcohol polyoxyethylene ether sulfate 1.3%, phenolsulfonic acid condensation substance sodium salt 2%, glycerol 2%, P-hydroxybenzoic acid Butyl ester 0.2%, organosilicon 0.1%, water are mended to 100%, put into high shear homogeneous emulsifying machine high speed and shear 25 minutes, then pump Sand milling 90 minutes to sand mill, i.e. obtain the suspending agent containing reactive compound 33% after filtration.

Embodiment 2:31% Aminothiocarbonylbenzene Aphox suspending agent (30:1)

By 31% reactive compound (30% Aminothiocarbonylbenzene and the compositions of 1% Aphox), alkylnaphthalene sulfonate 2.3%, acyl group glutamate 2%, phenolsulfonic acid condensation substance sodium salt 1%, methyl naphthalene sulfonate formaldehyde condensate 2%, epoxy are big Oleum Glycines 5%, glycerol 2%, organosilicon 0.1%, water are mended to 100%, put into high shear homogeneous emulsifying machine high speed and shear 25 Minute, then pump was to sand milling in sand mill 90 minutes, i.e. obtained the suspending agent containing reactive compound 31% after filtration.

Embodiment 3:30% Aminothiocarbonylbenzene Mobucin suspending agent (2:1)

By 30% reactive compound (20% Aminothiocarbonylbenzene and the compositions of 10% Mobucin), alkylnaphthalene sulfonate 2.6%, acyl group glutamate 2%, fatty alcohol polyoxyethylene ether sulfate 1%, phenolsulfonic acid condensation substance sodium salt 1.0%, high score Sub-polycarboxylate 2%, starch sodium octenyl succinate 2.4%, glycerol 2%, organic silicon defoamer 0.1%, deionized water are mended To 100%, put into high shear homogeneous emulsifying machine high speed and shear 25 minutes, then pump was to sand milling in sand mill 90 minutes, filter After i.e. obtain the suspending agent containing reactive compound 30%.

Embodiment 4:2.2% Aminothiocarbonylbenzene Mobucin suspending agent (10:1)

By 2.2% reactive compound (2% Aminothiocarbonylbenzene and the compositions of 0.2% Mobucin), alkylnaphthalene sulfonate 2%, acyl group glutamate 2%, fatty alcohol polyoxyethylene ether sulfate 1%, phenolsulfonic acid condensation substance sodium salt 1.0%, macromolecule Polycarboxylate 2.5%, starch sodium octenyl succinate 2%, glycerol 2%, organosilicon 0.1%, deionized water are mended to 100%, Put into high shear homogeneous emulsifying machine high speed to shear 25 minutes, then pump was to sand milling in sand mill 90 minutes, i.e. obtains and contain after filtration The suspending agent of reactive compound 2.2%.

Embodiment 5:18.6% Aminothiocarbonylbenzene Mobucin suspending agent (30:1)

By 18.6% reactive compound (18% Aminothiocarbonylbenzene and the compositions of 0.6% Mobucin), alkyl naphthalene sulfonic acid Salt 3.5%, acyl group glutamate 2%, fatty alcohol polyoxyethylene ether sulfate 1%, phenolsulfonic acid condensation substance sodium salt 1%, high score Sub-polycarboxylate 2.3%, starch sodium octenyl succinate 2%, glycerol 2%, deionized water are mended to 100%, put into height and cut Cut homogeneous emulsifying machine high speed to shear 25 minutes, then pump was to sand milling in sand mill 90 minutes, i.e. obtained containing reactive compound after filtration The suspending agent of 18.6%.

Embodiment 6:30% Aminothiocarbonylbenzene Methomyl suspending agent (1:2)

By 30% reactive compound (10% Aminothiocarbonylbenzene and the compositions of 20% Methomyl), alkylnaphthalene sulfonate 2.3%, acyl group glutamate 2%, fatty alcohol polyoxyethylene ether sulfate 1%, polymeric polycarboxylic acid salt 2.0%, sulfomethylated lignin Acid sodium 2%, SOPA-2702.3%, triphenyl phosphite 0.5%, ethylene glycol 2.0%, organosilicon 0.1%, water are mended to 100%, Put into high shear homogeneous emulsifying machine high speed to shear 25 minutes, then pump was to sand milling in sand mill 90 minutes, i.e. obtains and contain after filtration The suspending agent of reactive compound 30%.

Embodiment 7:44% Aminothiocarbonylbenzene Aphox suspending agent (1:10)

By 44% reactive compound (4% Aminothiocarbonylbenzene and the compositions of 40% Aphox), aliphatic alcohol polyethenoxy Ether 2.6%, tallow ethyoxyl amine salt 1.3%, acyl group glutamate 2%, polymeric polycarboxylic acid salt 3%, naphthalene sulfonic acid condensate Sodium salt 1%, dioctyl sodium sulphosuccinate salt 1%, carbamide 3%, organosilicon 0.01%, deionized water are added to 100%, put into Shear 20mAn to high shear homogeneous emulsifying machine high speed, more i.e. obtain containing reactive compound 44% with after high pressure homogenizer homogenizing Suspending agent.

Embodiment 8:50% Aminothiocarbonylbenzene meta-tolyl-N-methylcarbamate (MTMC) suspending agent (1:1)

By 50% reactive compound (25% Aminothiocarbonylbenzene and the compositions of 25% meta-tolyl-N-methylcarbamate (MTMC)), the oxidation of fatty alcohol ethyl Thing 2%, EO/PO block polyether 1%, alkylnaphthalene sulfonate 1.2%, polymeric polycarboxylic acid salt 4%, acrylate homopolymer sodium salt 1.5%, isopropanol 2%, organosilicon 0.01%, water are mended to 100%, put into high shear homogeneous emulsifying machine high speed and shear 30 points Clock, then transport in sand mill, the suspending agent that circulation sand milling i.e. obtains containing reactive compound 50% for 1-3 time.

Comparison medicament 1:10% Aminothiocarbonylbenzene suspending agent

By 10% Aminothiocarbonylbenzene, fatty alcohol ethyl oxide 2%, EO/PO block polyether 1%, alkylnaphthalene sulfonate 1.2%, polymeric polycarboxylic acid salt 4%, acrylate homopolymer sodium salt 1.5%, isopropanol 2%, organosilicon 0.01%, water are mended extremely 100%, put into high shear homogeneous emulsifying machine high speed and shear 30 minutes, then transport in sand mill, circulate sand milling 1-3 time and get final product 10% Aminothiocarbonylbenzene suspending agent.

Embodiment 9:40% Aminothiocarbonylbenzene meta-tolyl-N-methylcarbamate (MTMC) suspending agent (3:1)

By 40% reactive compound (30% Aminothiocarbonylbenzene and the compositions of 10% meta-tolyl-N-methylcarbamate (MTMC)), alkylnaphthalene sulfonate 2.4%, fatty alcohol-polyoxyethylene ether 3%, methyl naphthalene sulfonate formaldehyde condensate 2%, polymeric polycarboxylic acid salt 2.3%, epoxy Chloropropane 2%, glycerol 2%, xanthan gum 0.3%, organosilicon 0.01%, water are supplied and are sufficiently mixed, then it is equal to put into high shear Matter emulsifying agent high speed shears corase grind and homogenizing, then pump is to sand milling in sand mill, and sand milling, to certain particle diameter, i.e. obtains after refiltering and contains The suspending agent of reactive compound 40%.

Embodiment 10:35% Aminothiocarbonylbenzene Methomyl suspending agent (6:1)

By 35% reactive compound (30% Aminothiocarbonylbenzene and the compositions of 5% Methomyl), alkylnaphthalene sulfonate 3%, fatty alcohol polyoxyethylene ether sulfate 4.5%, phenolsulfonic acid condensation substance sodium salt 2%, methyl naphthalene sulfonate formaldehyde condensate 2%, propylene glycol 2%, organosilicon 0.1%, deionized water are mended to 100%, put into high shear homogeneous emulsifying machine high speed and shear 25 minutes, then pump was to sand milling in sand mill 90 minutes, i.e. obtained the suspending agent containing reactive compound 35% after filtration.

Embodiment 11:40% Aminothiocarbonylbenzene Methomyl suspending agent (1:1)

By 40% reactive compound (20% Aminothiocarbonylbenzene and the compositions of 20% Methomyl), the oxidation of fatty alcohol ethyl Thing 4%, acrylate homopolymer sodium salt 3%, polymeric polycarboxylic acid salt 2.8%, polyvinyl alcohol 0.5%, epoxy soybean oil 5%, urine Element 2%, organosilicon 0.1%, deionized water are mended to 100%, put into high shear homogeneous emulsifying machine high speed and shear 30 minutes, then Transport in sand mill, the suspending agent that circulation sand milling i.e. obtains containing reactive compound 40% for 1-3 time.

Embodiment 12:21% Aminothiocarbonylbenzene Methomyl suspending agent (20:1)

By 21% reactive compound (20% Aminothiocarbonylbenzene and the compositions of 1% Methomyl), fatty alcohol ethoxylate Compound 3%, alkylnaphthalene sulfonate 1%, fatty alcohol polyoxyethylene ether sulfate 4%, sodium metnylene bis-naphthalene sulfonate 1.5%, organic Silicon defoaming agent 0.2%, water are added to 100%, put into high shear homogeneous emulsifying machine high speed and shear 30mAn, more equal with high pressure The suspending agent containing reactive compound 21% is i.e. obtained after matter machine homogenizing.

Embodiment 13:22% Aminothiocarbonylbenzene Methomyl suspending agent (10:1)

By 22% reactive compound (20% Aminothiocarbonylbenzene and 2% Methomyl compositions), fatty alcohol-polyoxyethylene ether 3%, sodium metnylene bis-naphthalene sulfonate 2.5%, EO/PO block co-polyether 2%, maleic-acrylic acid homopolymer sodium salt 1.0%, Huang Virgin rubber 0.05%, Magnesiumaluminumsilicate 0.6%, glycerol 2%, phenyl salicylate 0.4%, organosilicon 0.01%, water are mended to 100%, Putting into high shear homogeneous emulsifying machine high speed to shear 20 minutes, then transport in sand mill, circulation sand milling i.e. obtains containing activity for 1-3 time The suspending agent of compound 22%.

Embodiment 14:11% Aminothiocarbonylbenzene Methomyl suspending agent (1:10)

By 11% reactive compound (1% Aminothiocarbonylbenzene and the compositions of 10% Methomyl) EO/PO block polyether 3.0%, naphthalene sulfonic acid condensate sodium salt 2.0%, polymeric polycarboxylic acid salt 4.0%, polyvinyl alcohol 0.5%, carbamide 2.0%, organic Silicon 0.1%, deionized water are mended to 100%, put into high shear homogeneous emulsifying machine high speed and shear 30 minutes, then transport to sand mill In, the suspending agent that circulation sand milling i.e. obtains containing reactive compound 11% for 1-3 time.

Embodiment 15:10.5% Aminothiocarbonylbenzene Benfuracard micro suspending agent (1:20)

By 10.5% reactive compound (0.5% Aminothiocarbonylbenzene and the compositions of 10% Benfuracard micro), fatty alcohol Ethyl oxide 2.4%, agriculture breast 600#1%, sulfomethylated lignin ester sodium 1.5%, calcium lignosulfonate 3.5%, polyvinyl alcohol 0.5%, epoxy soybean oil 5%, carbamide 2%, organosilicon 0.1%, water are mended to 100%, put in high shear homogeneous emulsifying machine High speed shear 30 minutes, then transport in sand mill, the suspending agent that circulation sand milling i.e. obtains containing reactive compound 10.5% for 1-3 time.

(2) preparation of cream

Embodiment 16:10% Aminothiocarbonylbenzene Bassa cream (1:1)

By 10% reactive compound (5% Aminothiocarbonylbenzene and the compositions of 5% Bassa), 12% Ketohexamethylene joins Mixing kettle, adds alkylphenol polyoxyethylene 7% after stirring and dissolving, calcium dodecyl benzene sulfonate 3%, trimethylbenzene supplies 100% Stir, obtain the cream containing reactive compound 10%.

Embodiment 17:15.5% Aminothiocarbonylbenzene Benfuracard micro cream (30:1)

By 15.5% reactive compound (15% Aminothiocarbonylbenzene and the compositions of 0.5% Benfuracard micro), 28% 2 Methylformamide joins mixing kettle, addition alkylphenol polyoxyethylene 7% after stirring and dissolving, calcium dodecyl benzene sulfonate 2%, Methyl oleate is supplied 100% and is stirred, and obtains the cream containing reactive compound 15.5%.

Embodiment 18:11% Aminothiocarbonylbenzene Benfuracard micro cream (10:1)

By 11% reactive compound (10% Aminothiocarbonylbenzene and the compositions of 1% Benfuracard micro), 22% dimethyl Methanamide joins mixing kettle, adds alkylphenol polyoxyethylene 7%, calcium dodecyl benzene sulfonate 2%, oleic acid after stirring and dissolving Methyl ester is supplied 100% and is stirred, and obtains the cream containing reactive compound 11%.

Embodiment 19:11% Aminothiocarbonylbenzene Benfuracard micro cream (1:10)

By 11% reactive compound (1% Aminothiocarbonylbenzene and the compositions of 10% Benfuracard micro), 6% dimethyl methyl Amide joins mixing kettle, adds alkylphenol polyoxyethylene 5%, calcium dodecyl benzene sulfonate 4%, oleic acid first after stirring and dissolving Ester is supplied 100% and is stirred, and obtains the cream containing reactive compound 11%.

Comparison medicament 2:20% Benfuracard micro cream

By 20% Benfuracard micro, 6% dimethylformamide joins mixing kettle, adds alkyl phenol polyoxy after stirring and dissolving Vinyl Ether 5%, calcium dodecyl benzene sulfonate 4%, methyl oleate is supplied 100% and is stirred, obtains containing 20% Benfuracard micro Cream.

Embodiment 20:15.5% Aminothiocarbonylbenzene Benfuracard micro cream (1:30)

By 15.5% reactive compound (0.5% Aminothiocarbonylbenzene and the compositions of 15% Benfuracard micro), 3% diformazan Base Methanamide joins mixing kettle, adds NPE 6.5%, calcium dodecyl benzene sulfonate after stirring and dissolving 2.5%, trimethylbenzene is supplied 100% and is stirred, and obtains the cream containing reactive compound 15.5%.

Embodiment 21:10% Aminothiocarbonylbenzene carbosulfan cream (1:1)

By 10% reactive compound (5% Aminothiocarbonylbenzene and the compositions of 5% carbosulfan), 12%N-methyl pyrrole Pyrrolidone joins mixing kettle, addition phenethyl phenol polyethenoxy ether 7% after stirring and dissolving, calcium dodecyl benzene sulfonate 3%, and two Toluene is supplied 100% and is stirred, and obtains the cream containing reactive compound 10%.

Embodiment 22:20.5% Aminothiocarbonylbenzene carbosulfan cream (40:1)

By 20.5% reactive compound (20.0% Aminothiocarbonylbenzene and the compositions of 0.5% carbosulfan), 28% Dimethylformamide joins mixing kettle, adds alkylphenol polyoxyethylene 7%, calcium dodecyl benzene sulfonate after stirring and dissolving 2%, trimethylbenzene is supplied 100% and is stirred, and obtains the cream containing reactive compound 20.5%.

Embodiment 23:11% Aminothiocarbonylbenzene carbosulfan cream (10:1)

By 11% reactive compound (10% Aminothiocarbonylbenzene and the compositions of 1% carbosulfan), 15%N-methyl Ketopyrrolidine joins mixing kettle, adds alkylphenol polyoxyethylene 4%, calcium dodecyl benzene sulfonate 5%, plant after stirring and dissolving Thing oil is supplied 100% and is stirred, and obtains the cream containing reactive compound 11%.

Embodiment 24:22% Aminothiocarbonylbenzene carbosulfan cream (1:10)

By 22% reactive compound (2% Aminothiocarbonylbenzene and the compositions of 20% carbosulfan), 6% dimethyl methyl Amide joins mixing kettle, addition phenethyl phenol polyethenoxy ether 6% after stirring and dissolving, calcium dodecyl benzene sulfonate 3.5%, and three Toluene is supplied 100% and is stirred, and obtains the cream containing reactive compound 22%.

Embodiment 25:15.5% Aminothiocarbonylbenzene carbosulfan cream (1:30)

By 15.5% reactive compound (0.5% Aminothiocarbonylbenzene and the compositions of 15% carbosulfan), 3% diformazan Base Methanamide joins mixing kettle, adds alkylphenol polyoxyethylene 6.5%, calcium dodecyl benzene sulfonate after stirring and dissolving 2.5%, dimethylbenzene is supplied 100% and is stirred, and obtains the cream containing reactive compound 15.5%.

(3) preparation of water dispersible granules

Embodiment 26:66% Aminothiocarbonylbenzene Mobucin water dispersible granules (1:10)

By 66% reactive compound (6% Aminothiocarbonylbenzene and the compositions of 60% Mobucin), EO/PO block polyether 7%, fatty alcohol-polyoxyethylene ether 2%, sodium sulfate 6%, xanthan gum 1%, Kaolin complement to 100%, are sufficiently mixed, then put into Shear corase grind and homogenizing to high shear homogenized milk agent high speed, then pump to certain particle diameter, reproduces to sand milling in sand mill, sand milling Grain molding i.e. obtains the water dispersible granules containing reactive compound 66%, and product cut size is 0.8-2mm.

Embodiment 27:36% Aminothiocarbonylbenzene pymetrozine water dispersing granule (8:1)

36% reactive compound (32% Aminothiocarbonylbenzene and the compositions of 4% pymetrozine), fatty alcohol-polyoxyethylene ether 4.0%, lignosulfonates 3.0%, sodium sulfate 15.0%, polyvinyl alcohol 2.0%, white carbon 10%, Kaolin are supplied 100%, then by comminution by gas stream, granulating and forming i.e. obtains the water dispersible granules containing reactive compound 36%, and product cut size is 0.8- 2mm。

(4) preparation of aqueous emulsion

Embodiment 28:5% Aminothiocarbonylbenzene aqueous carbosulfan emulsion (1:1)

By 5% reactive compound (2.5% Aminothiocarbonylbenzene and the compositions of 2.5% carbosulfan), 12% diformazan Base Methanamide joins mixing kettle, is added in mixing kettle addition alkylphenol polyoxyethylene 2%, polycarboxylate after stirring and dissolving 4%, calcium dodecyl benzene sulfonate 2%, stir, obtain oil phase, stand-by.Glycerol 3% and froth breaking is added in high shear still Agent 0.01%, water supplies 100%, stirs, and obtains aqueous phase.In high shear still, add oil phase, start cutter, high speed shear Stir 30 minutes, obtain the aqueous emulsion containing reactive compound 5%.

Embodiment 29:11% Aminothiocarbonylbenzene Benfuracard micro aqueous emulsion (1:10)

By 11% reactive compound (1% Aminothiocarbonylbenzene and the compositions of 10% Benfuracard micro), 12% dimethyl Methanamide joins mixing kettle, is added in mixing kettle addition alkylphenol polyoxyethylene 3%, polycarboxylate after stirring and dissolving 4%, calcium dodecyl benzene sulfonate 2%, stir, obtain oil phase, stand-by.Glycerol 3% and froth breaking is added in high shear still Agent 0.01%, water supplies 100%, stirs, and obtains aqueous phase.In high shear still, add oil phase, start cutter, high speed shear Stir 30 minutes, obtain the aqueous emulsion containing 11% reactive compound.

(5) preparation of wettable powder

Embodiment 30:50% Aminothiocarbonylbenzene Mobucin wettable powder (1:1)

By 50% reactive compound (25% Aminothiocarbonylbenzene and the compositions of 25% Mobucin), methyl naphthalene sulfonic acid sodium first Aldehyde condensate 1.8%, alkylphenol polyoxyethylene 2.2%, white carbon 2%, kieselguhr supply 100%, are sufficiently mixed, then pass through Superfine grinding, to certain particle diameter, obtains the wettable powder containing reactive compound 50%.

Embodiment 31:90% Aminothiocarbonylbenzene Mobucin wettable powder (1:40)

By 90% reactive compound (2.2% Aminothiocarbonylbenzene and the compositions of 87.8% Mobucin), methyl naphthalene sulfonic acid Sodium formaldehyde condensation substance 3.3%, polymeric polycarboxylic acid salt 5.2%, Kaolin supply 100%, then by superfine grinding to certain grain Footpath, obtains the wettable powder containing 90% reactive compound.

Embodiment 32:21% Aminothiocarbonylbenzene Mobucin wettable powder (1:20)

By 21% reactive compound (1% Aminothiocarbonylbenzene and the compositions of 20% Mobucin), sodium lauryl sulphate 1.5%, polymeric polycarboxylic acid salt 5%, precipitated calcium carbonate 3%, kieselguhr supply 100%, then by superfine grinding to certain grain Footpath, obtains the wettable powder containing reactive compound 21%.

Embodiment 33:15% Aminothiocarbonylbenzene Methomyl wettable powder (1:2)

By 15% reactive compound (5% Aminothiocarbonylbenzene and the compositions of 10% Methomyl), methyl naphthalene sulfonic acid sodium first Aldehyde condensate 1.2%, polymeric polycarboxylic acid salt 2.8%, white carbon 2%, precipitated calcium carbonate 3%, kieselguhr complement to 100%, It is sufficiently mixed, then by superfine grinding to certain particle diameter, obtains the wettable powder containing reactive compound 15%.

Embodiment 34 21% Aminothiocarbonylbenzene pymetrozine wettable powder (1:20)

By 21% reactive compound (1% Aminothiocarbonylbenzene and the compositions of 20% pymetrozine), calcium lignosulfonate 5%, alkylphenol polyoxyethylene 3%, pull open powder 5%, white carbon 6%, Kaolin complement to 100%, be sufficiently mixed, then pass through Superfine grinding, to certain particle diameter, obtains the wettable powder containing 21% reactive compound.

Embodiment 35 60% Aminothiocarbonylbenzene pymetrozine wettable powder (1:5)

By 60% reactive compound (10% Aminothiocarbonylbenzene and the compositions of 50% pymetrozine), calcium lignosulfonate 5%, methyl naphthalene sulfonic acid sodium 3%, polycarboxylate 5%, precipitated calcium carbonate 10%, Kaolin complement to 100%, are sufficiently mixed, then By superfine grinding to certain particle diameter, obtain the wettable powder containing reactive compound 60%.

(6) preparation of granule

Embodiment 36 1% Aminothiocarbonylbenzene Benfuracard micro granule (1:9)

By 1% reactive compound (0.1% Aminothiocarbonylbenzene and the compositions of 0.9% Benfuracard micro), starch 2.8%, polycarboxylate 2.5%, lauryl alcohol polyethylene glycol oxide base ether 3.5%, carbamide complement to 100%, are sufficiently mixed, then by squeezing Pressure pelletize, obtains the granule containing reactive compound 1%.

Embodiment 37 8.4% Aminothiocarbonylbenzene carbosulfan granule (1:20)

By 8.4% reactive compound (0.4% Aminothiocarbonylbenzene and the compositions of 8% carbosulfan), phenethyl phenol Polyoxyethylene ether 2.6%, sodium lauryl sulphate 3.2%, polyvinyl alcohol 2%, humic acids 2%, carbamide 6%, kieselguhr are supplied To 100%, it is sufficiently mixed, then by extruder grain, obtains the granule containing reactive compound 8.4%.

Two, Assays Example

The potentiation compounding for determining two kinds of reactive compounds, the applicant uses both reactive compounds to carry out Toxicity Determination, synergy uses the abundant method of Sun Yun to calculate co-toxicity coefficient (CTC) and evaluates mixed effect.

Test data computational methods:

Actual measurement toxicity index (ATI)=(standard agent LC50/ reagent agent LC50) × 100

Percentage composition+B medicament the toxicity index of A in theoretical toxicity index (TTI)=A medicament toxicity index × mixture × mixed The percentage composition of B in agent

Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theory toxicity index (TTI)] × 100

Data processing method: prevention effect is converted into probability value (y), liquor strength (μ g/ml) is converted into logarithm value X (), calculates concentration LC50 in virulence equation and suppression with method of least square, calculate the toxicity index of medicament according to the abundant method of Sun Yun and be total to Poison coefficient (CTC).

Evaluation criterion: when CTC≤80, then compositions shows as antagonism, as 80 ＜ CTC ＜ 120, then compositions performance For summation action, when CTC >=120, then compositions shows as potentiation.

Bioassay example 1 prevents and treats planthopper activity test (rice-stem dipping method)

Test method: with reference to " NY/T1154.11-2008 farm-chemical indoor determination test rule insecticide the 11st part: Rice-stem dipping method ".

Table 1 Aminothiocarbonylbenzene and pymetrozine mixture are to planthopper toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	38.18	100.00	/	/
Pymetrozine (B)	65.21	58.55	/	/
					A:B=40:1	31.4	121.59	98.99	122.83
A:B=30:1	28.85	132.34	98.66	134.13
					A:B=24:1	26.73	142.84	98.34	145.24
A:B=20:1	27.12	140.78	98.03	143.62
					A:B=15:1	25.37	150.49	97.41	154.50
A:B=10:1	25.03	152.54	96.23	158.51
					A:B=8:1	20.82	183.38	95.39	192.24

A:B=4:1	22.6	168.94	91.71	184.21
					A:B=1:1	26.73	142.84	79.27	180.18
A:B=1:4	32.8	116.40	66.84	174.15
					A:B=1:8	33.5	113.97	63.15	180.46
A:B=1:10	35.03	108.99	62.32	174.90
					A:B=1:15	41.9	91.12	61.14	149.04
A:B=1:20	44.7	85.41	60.52	141.13
					A:B=1:24	46.2	82.64	60.21	137.26
A:B=1:30	48.6	78.56	59.89	131.18
					A:B=1:40	50.3	75.90	59.56	127.44

Table 2 Aminothiocarbonylbenzene and Mobucin mixture are to planthopper toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	37.96	100.00	/	/
Mobucin (C)	55.01	69.01	/	/
					A:C=40:1	31.25	121.47	99.24	122.40
A:C=30:1	30.15	125.90	99.00	127.18
					A:C=20:1	29.18	130.09	98.52	132.04
A:C=14:1	26.55	142.98	97.93	145.99
					A:C=10:1	27.59	137.59	97.18	141.58
A:C=2:1	23.76	159.76	89.67	178.17
					A:C=1:1	26.94	140.91	84.50	166.75
A:C=1:2	32.87	115.49	79.34	145.56
					A:C=1:10	33.12	114.61	71.82	159.58
A:C=1:14	37.16	102.15	71.07	143.73
					A:C=1:20	40.08	94.71	70.48	134.38
A:C=1:30	41.98	90.42	70.01	129.17
					A:C=1:40	43.64	86.98	69.76	124.69

Table 3 Aminothiocarbonylbenzene and carbosulfan mixture are to planthopper toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	37.82	100.00	/	/
Carbosulfan (D)	63.21	59.83	/	/
					A:D=40:1	30.52	123.92	99.02	125.14
A:D=30:1	29.68	127.43	98.70	129.10
					A:D=22:1	28.35	133.40	98.25	135.78
A:D=10:1	27.29	138.59	96.35	143.84
					A:D=1:1	33.19	113.95	79.92	142.59
A:D=1:10	37.85	99.92	63.48	157.40
					A:D=1:20	35.36	106.96	61.75	173.22
A:D=1:30	42.33	89.35	61.13	146.16
					A:D=1:40	45.75	82.67	60.81	135.94

Table 4 Aminothiocarbonylbenzene and Bassa mixture are to planthopper toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	38.46	100.00	/	/
Bassa (E)	130.25	29.53	/	/
					A:E=40:1	31.79	120.98	98.28	123.10
A:E=30:1	29.93	128.50	97.73	131.49
					A:E=20:1	27.16	141.61	96.64	146.52
A:E=10:1	25.22	152.50	93.59	162.94
					A:E=1:1	40.44	95.10	64.76	146.85
A:E=1:10	76.21	50.47	35.93	140.44
					A:E=1:20	86.2	44.62	32.88	135.68
A:E=1:30	89.63	42.91	31.80	134.93
					A:E=1:40	95.86	40.12	31.25	128.40

Table 5 Aminothiocarbonylbenzene and meta-tolyl-N-methylcarbamate (MTMC) mixture are to planthopper toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	38.16	100.00	/	/
Meta-tolyl-N-methylcarbamate (MTMC) (F)	74.25	51.39	/	/
					A:F=40:1	31.25	122.11	98.81	123.58
A:F=30:1	29.81	128.01	98.43	130.05
					A:F=20:1	28.36	134.56	97.69	137.74
A:F=10:1	28.68	133.05	95.58	139.21
					A:F=1:1	34.67	110.07	75.70	145.40
A:F=1:10	50.56	75.47	55.81	135.23
					A:F=1:20	52.96	72.05	53.71	134.16
A:F=1:30	54.53	69.98	52.96	132.13
					A:F=1:40	58.13	65.65	52.58	124.85

From toxicity test result table 1-table 5, when preventing and treating rice hoppers, Aminothiocarbonylbenzene is multiple with pymetrozine etc. Having obvious synergistic function in the range of fitting over 1:40～40:1, co-toxicity coefficient is all higher than 120.

Bioassay example 2 prevents and treats black bean aphid activity test

Experimental technique: with reference to NYT 1154.14-2008 farm-chemical indoor determination test rule insecticide the 14th part: Leaf dipping method.

Table 6 Aminothiocarbonylbenzene and Mobucin mixture are to black bean aphid toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	22.72	100.00	/	/
Mobucin (G)	15.94	142.53	/	/
					A:G=40:1	17.25	131.71	101.04	130.36
A:G=30:1	16.9	134.44	101.37	132.62
					A:G=20:1	17.13	132.63	102.03	130.00
A:G=10:1	15.73	144.44	103.87	139.06
					A:G=1:1	12.97	175.17	121.27	144.45
A:G=1:10	10.65	213.33	138.67	153.84

A:G=1:20	11.49	197.74	140.51	140.73
					A:G=1:30	11.3	201.06	141.16	142.43
A:G=1:40	12.25	185.47	141.50	131.08

Table 7 Aminothiocarbonylbenzene and Benfuracard micro mixture are to black bean aphid toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	22.31	100.00	/	/
Benfuracard micro (H)	83.55	26.70	/	/
					A:H=50:1	21.8	102.34	98.56	103.83
A:H=40:1	18.3	121.91	98.21	124.13
					A:H=30:1	17.25	129.33	97.64	132.47
A:H=20:1	18.24	122.31	96.51	126.74
					A:H=10:1	16.92	131.86	93.34	141.27
A:H=5:1	15.26	146.20	87.78	166.54
					A:H=1:1	21.63	103.14	63.35	162.81
A:H=1:5	33.42	66.76	38.92	171.53
					A:H=1:10	35.7	62.49	33.37	187.30
A:H=1:20	51.06	43.69	30.19	144.71
					A:H=1:30	57.53	38.78	29.07	133.42
A:H=1:40	61.37	36.35	28.49	127.60

Table 8 Aminothiocarbonylbenzene and Aphox mixture are to black bean aphid toxicity test result

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	22.78	100.00	/	/
Aphox (J)	155.24	14.67	/	/
					A:J=40:1	18.50	123.14	97.92	125.75
A:J=30:1	17.54	129.87	97.25	133.55
					A:J=20:1	16.53	137.81	95.94	143.65
A:J=10:1	17.70	128.70	92.24	139.52
					A:J=2:1	21.19	107.50	71.56	150.23
A:J=1:1	27.14	83.94	57.34	146.39

A:J=1:2	32.24	70.66	43.12	163.88
					A:J=1:10	72.33	31.49	22.43	140.41
A:J=1:20	89.74	25.38	18.74	135.48
					A:J=1:30	98.85	23.05	17.43	132.24
A:J=1:40	108.38	21.02	16.76	125.45

Table 9 Aminothiocarbonylbenzene and Methomyl mixture are to black bean aphid toxicity test

Process	LC50(μg/ml)	ATI	TTI	CTC
					Aminothiocarbonylbenzene (A)	22.15	100	/	/
Methomyl (K)	160.52	13.8	/	/
					A:K=40:1	18.02	122.92	97.9	125.56
A:K=30:1	16.05	138.01	97.22	141.95
					A:K=20:1	16.39	135.14	95.9	140.93
A:K=15:1	15.28	144.96	94.61	153.22
					A:K=8:1	15.41	143.74	90.42	158.96
A:K=1:1	25.18	87.97	56.9	154.6
					A:K=1:10	55.8	39.7	21.64	183.47
A:K=1:20	73.7	30.05	17.9	167.87
					A:K=1:30	85.6	25.88	16.58	156.07
A:K=1:40	102.8	21.55	15.9	135.5

From toxicity test result table 6-table 9, when preventing and treating black bean aphid, Aminothiocarbonylbenzene is multiple with Benfuracard micro etc. Having obvious synergistic function in the range of fitting over 1:40～40:1, co-toxicity coefficient is all higher than 120.

Three, field test embodiment

Experimental subject: in May, 2013 occurs abiogenous in periphery rice field, Luo Lai village, Xixiangtang District, Nanning Population.

Test method: in the tillering stage (mid-May) of Oryza sativa L. morning, all medicaments are pressed actual dosage, are added 60L/ mu Water, uniformly sprays medicinal liquid in rice clump base portion after stirring evenly.With reference to GB/T 17980.4-2000 pesticide field efficacy medicine test criterion (1) insecticide control planthopper.

Comparison medicament

Comparison medicament 1:10% Aminothiocarbonylbenzene suspending agent, self-control；

Comparison medicament 2:20% Benfuracard micro cream, self-control；

Comparison medicament 3:25% meta-tolyl-N-methylcarbamate (MTMC) wettable powder, Shaanxi Xiannong Bio-Technology Co., Ltd., registration card number PD20083375；

Comparison medicament 4:10% Methomyl wettable powder, Shaanxi Meibang Pesticide Co., Ltd., registration card PD20082615；

Comparison medicament 5:50% pymetrozine water dispersing granule, Zhejiang Shenghua Biok Biology Co., Ltd., registration card PD20131334；

Comparison medicament 6:20% carbosulfan cream, Chemical Co., Ltd. of Shandong Essen, registration card PD20081548；

Comparison medicament 7:20% Mobucin cream, Jiangxi Wei Niu crop science company limited, registration card PD20080048；

Comparison medicament 8:20% Bassa cream, Jiangxi Wei Niu crop science company limited, registration card PD20083707.

The test of pesticide effectiveness result of planthopper prevented and treated by table 10

From the point of view of above field efficacy, the compound synergic effect of the present composition is obvious, and the preventive effect after compounding is the highest In each comparison medicament.

The compound synergic effect of the present composition, it is not limited to the activity experiment listed by invention.The verified present invention Compositions, sucking pest preventing and treating has broad application prospects, particularly planthopper, thrips, aphid, red The upper effect of Aranea preventing and treating is the most prominent.The present invention also has preferably imitation to some lepidoptera pests simultaneously, is a kind of wide spectrum Insecticide.

Although the bromo-N-of reactive compound I 3-[4-chloro-2-methyl-6-(methylamino thioformyl) benzene] in the present invention- 1-(3-chloropyridine-2-base)-1H-pyrazoles-5-Methanamide and elite insecticidal active compound I I are known compound, Its activity and insecticidal effect are not the simple superposition of each composition activity, and both is compounding compared with existing unitary agent, except tool Having outside significant insecticidal effect, and have significant potentiation, good to crop safety, the safety meeting pesticidal preparations is wanted Ask, be then non-obvious for those skilled in the art.

Claims (8)

1. the Pesticidal combination preventing and treating sucking pest, it is characterised in that: described Pesticidal combination is by insecticidal activity Compound I and insecticidal active compound II composition, described insecticidal active compound I is Aminothiocarbonylbenzene, and its chemical name is The bromo-N-of 3-[4-chloro-2-methyl-6-(methylamino thioformyl) benzene]-1-(3-chloropyridine-2-base)-1H-pyrazoles-5-formyl Amine；Described insecticidal active compound II is pymetrozine；

The weight ratio of described insecticidal active compound I and insecticidal active compound II is 1:40～40:1.

A kind of Pesticidal combination preventing and treating sucking pest the most according to claim 1, it is characterised in that kill described in: The weight ratio of worm reactive compound I and insecticidal active compound II is 1:30～30:1.

3. an insecticide, it is characterised in that: described insecticide is by a kind of preventing and treating pierce-suck type mouth described in claim 1 or 2 The Pesticidal combination of device insect and adjuvant form, wherein, described Pesticidal combination account for described insecticidal total weight 1%～ 90%.

Insecticide the most according to claim 3, it is characterised in that: described Pesticidal combination accounts for described insecticidal total weight 20%～60%.

Insecticide the most according to claim 4, it is characterised in that: described Pesticidal combination accounts for described insecticidal total weight 20%～40%.

6. according to the insecticide described in claim 3 or 4, it is characterised in that: the dosage form of described insecticide be wettable powder, Water dispersible granules, cream, aqueous emulsion, suspending agent or granule.

7. the application in preventing and treating sucking pest of the insecticide according to any one of claim 3-6.

The insecticide the most according to claim 7 application in preventing and treating sucking pest, it is characterised in that: in preventing and treating To planthopper, the application of aphid.