CN103503876B - A kind of brominated worm Benzoylamide and the Pesticidal combination of neires toxin - Google Patents
A kind of brominated worm Benzoylamide and the Pesticidal combination of neires toxin Download PDFInfo
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- CN103503876B CN103503876B CN201210223031.4A CN201210223031A CN103503876B CN 103503876 B CN103503876 B CN 103503876B CN 201210223031 A CN201210223031 A CN 201210223031A CN 103503876 B CN103503876 B CN 103503876B
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- worm benzoylamide
- benzoylamide
- bromine worm
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- pesticidal combination
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- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title claims abstract description 121
- 230000000361 pesticidal effect Effects 0.000 title claims abstract description 17
- 239000003053 toxin Substances 0.000 title claims abstract description 13
- 231100000765 toxin Toxicity 0.000 title claims abstract description 13
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims abstract description 107
- 229910052794 bromium Inorganic materials 0.000 claims abstract description 107
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims abstract description 104
- 229910000366 copper(II) sulfate Inorganic materials 0.000 claims abstract description 37
- DNVLJEWNNDHELH-UHFFFAOYSA-N thiocyclam Chemical compound CN(C)C1CSSSC1 DNVLJEWNNDHELH-UHFFFAOYSA-N 0.000 claims abstract description 35
- QSOHVSNIQHGFJU-UHFFFAOYSA-L thiosultap disodium Chemical compound [Na+].[Na+].[O-]S(=O)(=O)SCC(N(C)C)CSS([O-])(=O)=O QSOHVSNIQHGFJU-UHFFFAOYSA-L 0.000 claims abstract description 35
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims abstract description 34
- 239000000203 mixture Substances 0.000 claims abstract description 31
- 241000238631 Hexapoda Species 0.000 claims abstract description 24
- 239000000375 suspending agent Substances 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 16
- 241000008892 Cnaphalocrocis patnalis Species 0.000 claims description 12
- 241000500437 Plutella xylostella Species 0.000 claims description 12
- 241000426497 Chilo suppressalis Species 0.000 claims description 8
- 239000000839 emulsion Substances 0.000 claims description 7
- 239000003094 microcapsule Substances 0.000 claims description 7
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 239000004563 wettable powder Substances 0.000 claims description 6
- 241001124076 Aphididae Species 0.000 claims description 5
- 241001414720 Cicadellidae Species 0.000 claims description 5
- 241001498622 Cixius wagneri Species 0.000 claims description 5
- 241001517923 Douglasiidae Species 0.000 claims description 5
- 241001046947 Ectropis obliqua Species 0.000 claims description 5
- 240000001307 Myosotis scorpioides Species 0.000 claims description 5
- 241001465818 Orseolia oryzae Species 0.000 claims description 5
- 241000907661 Pieris rapae Species 0.000 claims description 5
- 241001249129 Scirpophaga incertulas Species 0.000 claims description 5
- 241000256247 Spodoptera exigua Species 0.000 claims description 5
- 241001414989 Thysanoptera Species 0.000 claims description 5
- 241000196324 Embryophyta Species 0.000 claims description 3
- 241000607479 Yersinia pestis Species 0.000 abstract description 21
- 239000000575 pesticide Substances 0.000 abstract description 17
- 150000001875 compounds Chemical class 0.000 abstract description 4
- 238000012271 agricultural production Methods 0.000 abstract description 2
- 230000007423 decrease Effects 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 244000144977 poultry Species 0.000 abstract description 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 29
- 238000013329 compounding Methods 0.000 description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 21
- 230000003449 preventive effect Effects 0.000 description 18
- 239000002270 dispersing agent Substances 0.000 description 12
- 239000013530 defoamer Substances 0.000 description 10
- 239000000080 wetting agent Substances 0.000 description 10
- 239000003795 chemical substances by application Substances 0.000 description 9
- 239000008367 deionised water Substances 0.000 description 9
- 229910021641 deionized water Inorganic materials 0.000 description 9
- 239000012071 phase Substances 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 235000007164 Oryza sativa Nutrition 0.000 description 7
- 230000002528 anti-freeze Effects 0.000 description 7
- 239000000470 constituent Substances 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 235000013311 vegetables Nutrition 0.000 description 7
- 239000003995 emulsifying agent Substances 0.000 description 6
- 239000000945 filler Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 206010067482 No adverse event Diseases 0.000 description 5
- 230000010165 autogamy Effects 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 230000002265 prevention Effects 0.000 description 5
- 240000007124 Brassica oleracea Species 0.000 description 4
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 4
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 4
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 4
- -1 Cupric sulfate compound Chemical class 0.000 description 4
- 241000209094 Oryza Species 0.000 description 4
- 241001525654 Phyllocnistis citrella Species 0.000 description 4
- 241000255972 Pieris <butterfly> Species 0.000 description 4
- 239000011230 binding agent Substances 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 235000009566 rice Nutrition 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- 231100000820 toxicity test Toxicity 0.000 description 4
- 206010011732 Cyst Diseases 0.000 description 3
- 240000007594 Oryza sativa Species 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 208000031513 cyst Diseases 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 238000013401 experimental design Methods 0.000 description 3
- 229920002521 macromolecule Polymers 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 244000241257 Cucumis melo Species 0.000 description 2
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 2
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000002917 insecticide Substances 0.000 description 2
- 235000021374 legumes Nutrition 0.000 description 2
- 239000010871 livestock manure Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000003002 pH adjusting agent Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- 241000243812 Arenicola marina Species 0.000 description 1
- 241000488583 Panonychus ulmi Species 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 238000000498 ball milling Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000003958 fumigation Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000010413 mother solution Substances 0.000 description 1
- 231100000194 ovacidal Toxicity 0.000 description 1
- 230000003151 ovacidal effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses the Pesticidal combination of a kind of brominated worm Benzoylamide and neires toxin, Pesticidal combination containing active components A Yu active component B, active components A is selected from bromine worm Benzoylamide, active component B is selected from any one compound following: thiocyclam, dimehypo, Cupric sulfate, and the weight ratio of active components A and active component B is 1: 80～60: 1.The present composition has potentiation to the various pests of harm agricultural production, decreases pesticide usage amount, reduces pesticide residual quantity on crop, alleviate environmental pollution, and to person poultry safety, Environmental compatibility is good, and insect is not likely to produce Drug resistance.<!--1-->
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application on crop pests of the Pesticidal combination of a kind of brominated worm Benzoylamide and neires toxin.
Background technology
Sandworm toxin insecticide, has and tags and stomach poison function, also has certain interior suction and fumigation action, and can ovicidal.Slower to the toxic effect of insect, poisoning the lighter can bring back to life sometimes.It disappears comparatively fast in plant, and the longevity of residure is shorter, and during results, the residual quantity in crop is little.
But, in the real process of agricultural production, pest control is easiest to generate the problem that the generation of pest resistance to insecticide.Different cultivars composition compounds, and is to prevent and treat the method that resistant insect is the most common.Heterogeneity compounds, according to practical application effect, judge certain compounding be potentiation, add and or antagonism.In most cases, the compounding effect of pesticide is all additive effect, really has potentiation to lack, especially potentiation clearly, the highest compounding the most less of co-toxicity coefficient.Compounding through inventor is studied very much, good potentiation can be produced after finding to compound bromine worm Benzoylamide with thiocyclam, dimehypo, Cupric sulfate, and the openest with the relevant report that thiocyclam, dimehypo, Cupric sulfate compound about bromine worm Benzoylamide.
Summary of the invention
The purpose of the present invention is to propose to that there is synergistic function, the Pesticidal combination of use cost is low, preventive effect is good brominated worm Benzoylamide and neires toxin.
A kind of brominated worm Benzoylamide and the Pesticidal combination of neires toxin, containing active components A and active component B, it is characterized in that: active components A is 1 80 ~ 60 1 with the weight ratio of active component B, described active components A is selected from bromine worm Benzoylamide, active component B is selected from thiocyclam, dimehypo, one of Cupric sulfate is planted, active components A and the preferred weight ratio of active component B are 1 60 ~ 40 1, more preferably bromine worm Benzoylamide is 1 40 ~ 51 with the weight ratio of thiocyclam, bromine worm Benzoylamide is 1 40 ~ 51 with the weight ratio of dimehypo, bromine worm Benzoylamide is 1 50 ~ 11 with the weight ratio of Cupric sulfate；Most preferably bromine worm Benzoylamide is 1 30 ~ 11 with the weight ratio of thiocyclam, and bromine worm Benzoylamide is 1 30 ~ 11 with the weight ratio of dimehypo, and bromine worm Benzoylamide is 1 40 ~ 15 with the weight ratio of Cupric sulfate.
Described brominated worm Benzoylamide is used for preventing and treating the application of crop pests with the Pesticidal combination of neires toxin, and described crops include cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop；Described insect includes striped rice borer, yellow rice borer, rice leaf roller, thrips, leafhopper, pachydiplosis oryzae, plant hopper, aphid, caterpillar, leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea geometrid.
Active components A, the weight ratio of active component B are 1 80 ~ 60 1.Generally in compositions weight percentage is gross weight 0.5%～the 90% of active component, it is preferably 5%～80%.According to different preparation types, active component content scope is different.Generally, liquid preparation contains the active substance of by weight 1%～70%, preferably 5%～50%；Solid preparation contains the active substance of by weight 5%～80%, preferably 10%～80%.
The Pesticidal combination of the present invention at least contains a kind of surfactant, active component dispersion in water when being beneficial to use.Surface-active contents is the 5%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by the Pesticidal combination of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, preparation can also contain disintegrating agent known in those skilled in the art, antifreeze etc..
The Pesticidal combination of the present invention through dilution or directly can be used before use by user.Its preparation can be prepared by common processing method known in those skilled in the art, one or more in surfactant such as dispersant, stabilizer, wetting agent, binding agent, defoamer etc. will be added after active substance mixes with liquid flux or solid carrier.
The Pesticidal combination of the present invention, acceptable dosage form on any pesticide can be processed on demand, the most excellent dosage form is: soluble powder, wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, microcapsule suspending agent, it is also possible to make water preparation, suspension emulsion, microcapsule suspension-suspendinagent agent.
Compositions includes following constituent content when making soluble powder: active components A 0.5% ~ 60%, active component B0.5% ~ 80%, dispersant 2% ~ 8%, wetting agent 1%-7%, filler surplus.
Compositions comprises following constituent content when making wettable powder: active components A 0.5% ~ 60%, active component B0.5% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Compositions includes following constituent content when making water dispersible granules: active components A 0.5% ~ 60%, active component B0.5% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrating agent 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Compositions includes following constituent content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickening agent 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Compositions comprises following constituent content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifying agent 1% ~ 15%, antifreeze 0 ~ 8%, thickening agent 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Compositions comprises following constituent content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 20%, emulsifying agent 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, stabilizer 0 ~ 4%, deionized water adds to 100%.
Compositions includes following constituent content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 10%, emulsifying agent 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
The soluble powder the key technical indexes of the present invention:
The wettable powder the key technical indexes of the present invention:
The water dispersible granules the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The microcapsule suspending agent the key technical indexes of the present invention:
It is an advantage of the current invention that:
(1), after bromine worm Benzoylamide compounds with thiocyclam, dimehypo, Cupric sulfate, there is obvious potentiation and lasting effect；(2) cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, the striped rice borer of green manure pasture crop, yellow rice borer, rice leaf roller, thrips, leafhopper, pachydiplosis oryzae, plant hopper, aphid, caterpillar, leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea geometrid etc. all there is greater activity；(3) decrease pesticide usage amount, reduce pesticide residual quantity on crop, alleviate environmental pollution；(4) to person poultry safety, Environmental compatibility is good, and preparation adhesion strength strengthens, resistance of rainwater washing against.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are all weight percentage, but the invention is not limited in this.
Application Example one
Example 1 ~ 10 soluble powder
By bromine worm Benzoylamide, active component B, dispersant, wetting agent, filler mixing, mix homogeneously in mixed cylinder, remix uniformly after jet mill is pulverized, i.e. can be made into soluble powder product of the present invention.Specifically it is shown in Table 1,2.
Table 1 example 1 ~ 5 component and content
Table 2 example 6 ~ 10 component and content
Example 11 ~ 20 wettable powder
By bromine worm Benzoylamide, active component B, dispersant, wetting agent, filler mix homogeneously in mixed cylinder, remix uniformly after jet mill is pulverized, can be prepared by wettable powder product of the present invention, be specifically shown in Table 3,4.
Table 3 example 11 ~ 15 component and content
Table 4 example 16 ~ 20 component and content
Example 21 ~ 30 water dispersible granules
Bromine worm Benzoylamide, active component B, dispersant, wetting agent, disintegrating agent, filler etc. are obtained through comminution by gas stream together the particle diameter needed, adds other auxiliary agents such as binding agent (can add and can be not added with), obtain granulation materials.Through in item is quantitatively sent into fluidized bed granulating dryer and granulation and dried, can be prepared by water dispersible granules product of the present invention, be specifically shown in Table 5,6.
Table 5 example 21 ~ 25 component and content
Table 6 example 26 ~ 30 component and content
Example 31 ~ 40 suspending agent
By dispersant, wetting agent, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with), through high speed shear mix homogeneously, add bromine worm Benzoylamide, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can be prepared by suspending agent product of the present invention, is specifically shown in Table 7,8.
Table 7 example 31 ~ 35 component and content
Table 8 example 36 ~ 40 component and content
Example 41 ~ 45 aqueous emulsion
Bromine worm Benzoylamide, active component B, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase；Deionized water, antifreeze (can add and can be not added with), thickening agent (can add and can be not added with), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase adding oil phase, surplus deionized water is supplied；Can be prepared by aqueous emulsion product of the present invention, be specifically shown in Table 9.
Table 9 example 41 ~ 45 component and content
Example 46 ~ 50 microemulsion
Bromine worm Benzoylamide, active component B are dissolved in equipped with in the homogenizer of solvent, emulsifying agent, antifreeze (can add and can be not added with), defoamer are joined in the homogenizer equipped with above-mentioned solution, surplus deionized water strongly mixes after supplying and homogenizes, and finally obtains the microemulsion product of the present invention that clear appearance is transparent.Specifically it is shown in Table 10.
Table 10 example 46 ~ 50 component and content
Thiocyclam, dimehypo, Cupric sulfate in table 1 ~ 10 are exchanged, novel formulation can be prepared.
Example 51 ~ 53 microcapsule suspending agent
By bromine worm Benzoylamide, active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined containing emulsifying agent, pH adjusting agent, dispersant, defoamer aqueous phase solution in, surplus deionized water is supplied, and bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, make the present composition finely disseminated microcapsule suspending agent product, be specifically shown in Table 11.
Table 11 example 51 ~ 53 component and content
The embodiment of the present invention is the method using Toxicity Determination and field test to combine.First pass through Toxicity Determination, the co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are compounding by a certain percentage, CTC ＜ 80 is antagonism, 80≤CTC≤120 are summation action, CTC ＞ 120 is potentiation, on this basis, then carries out field test.
Test method: respectively the mother solution of each mixed agent is diluted to during test five series concentration, is respectively placed in beaker standby.Use the method that first leaching leaf is followed by worm, take out after blade of the same size not in contact with any medicament is soaked 5s in the medicinal liquid configured, naturally dry, put in insect box, then connect for examination larva, raise under the conditions of 25 DEG C, often process 3 times and repeat, often repeating examination borer population used is 50, sets blank simultaneously, checks dead borer population in 72h, calculate mortality rate and corrected mortality, try to achieve virulence regression equation and calculate LC50Value.If comparison mortality rate is more than 10%, then it is considered as invalid test.Computing formula is as follows:
Insect corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) is converted into logarithm value (x), draws virulence regression equation with method of least square, and thus calculate the value of every kind of medicament.Co-toxicity coefficient CTC is calculated according to the abundant equation of Sun Yun.Computing formula is following (with bromine worm Benzoylamide as standard agent, its toxicity index is 100):
TI × the P of the theoretical toxicity index (TTI) of M=bromine worm BenzoylamideBromine worm BenzoylamideTI × the P of+effective active composition BEffective active composition B
In formula: M is the mixture of different ratio
PEffective active composition BFor the ratio that effective active composition B is shared in the composition
PBromine worm BenzoylamideFor the ratio that bromine worm Benzoylamide is shared in the composition
B plants selected from one of thiocyclam, dimehypo, Cupric sulfate.
Application Example two:
For examination insect: rice-stem borer
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine bromine worm Benzoylamide and the former medicine of thiocyclam and effective lethasl concentration scope of the two different ratio mixture through pilot study.
Toxicity test result
Table 12 bromine worm Benzoylamide toxicity test analysis of results table to rice-stem borer compounding with thiocyclam
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.61 | — |
| Thiocyclam | — | 8.94 | — |
| Bromine worm Benzoylamide thiocyclam | 1:80 | 4.09 | 187.05 |
| Bromine worm Benzoylamide thiocyclam | 1:60 | 3.57 | 204.61 |
| Bromine worm Benzoylamide thiocyclam | 1:40 | 3.01 | 222.80 |
| Bromine worm Benzoylamide thiocyclam | 1:30 | 2.65 | 234.19 |
| Bromine worm Benzoylamide thiocyclam | 1:20 | 2.19 | 247.36 |
| Bromine worm Benzoylamide thiocyclam | 1:15 | 1.86 | 259.32 |
| Bromine worm Benzoylamide thiocyclam | 1:10 | 1.6 | 249.28 |
| Bromine worm Benzoylamide thiocyclam | 1:1 | 0.48 | 237.93 |
| Bromine worm Benzoylamide thiocyclam | 5:1 | 0.32 | 225.67 |
| Bromine worm Benzoylamide thiocyclam | 15:1 | 0.3 | 215.91 |
| Bromine worm Benzoylamide thiocyclam | 30:1 | 0.31 | 202.87 |
| Bromine worm Benzoylamide thiocyclam | 40:1 | 0.33 | 189.15 |
| Bromine worm Benzoylamide thiocyclam | 60:1 | 0.37 | 167.42 |
nullAs shown in Table 12，Bromine worm Benzoylamide and thiocyclam compound the proportioning of preventing and treating rice-stem borer when 1 80 ~ 60 1，Co-toxicity coefficient is all higher than 120，Illustrate that both all show potentiation at mixture in the range of 1 80 ~ 60 1，When the proportioning of bromine worm Benzoylamide and thiocyclam is 1 40 ~ 51，Potentiation is the most prominent，Co-toxicity coefficient is all higher than 220，Test through applicant and find that bromine worm Benzoylamide is 5:1 with the optimum ratio of thiocyclam、1:1、1:5、1:6、1:7、1:8、1:9、1:10、1:11、1:12、1:13、1:14、1:15、1:16、1:17、1:18、1:19、1:20、1:21、1:22、1:23、1:24、1:25、1:30、1、1:35、1:40，Wherein when bromine worm Benzoylamide and thiocyclam weight ratio are 1 15, co-toxicity coefficient is maximum，Potentiation is the most obvious.
Application Example three
For examination insect: Oryza sativa L. rice leaf roller
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine bromine worm Benzoylamide and the former medicine of dimehypo and effective lethasl concentration scope of the two different ratio mixture through pilot study.
Table 13 bromine worm Benzoylamide toxicity test analysis of results table to Oryza sativa L. rice leaf roller compounding with dimehypo
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.54 | — |
| Dimehypo | — | 8.07 | — |
| Bromine worm Benzoylamide dimehypo | 1:80 | 3.62 | 190.19 |
| Bromine worm Benzoylamide dimehypo | 1:60 | 3.15 | 208.52 |
| Bromine worm Benzoylamide dimehypo | 1:40 | 2.68 | 224.70 |
| Bromine worm Benzoylamide dimehypo | 1:30 | 2.38 | 233.87 |
| Bromine worm Benzoylamide dimehypo | 1:20 | 1.98 | 244.93 |
| Bromine worm Benzoylamide dimehypo | 1:15 | 1.66 | 259.76 |
| Bromine worm Benzoylamide dimehypo | 1:10 | 1.43 | 248.86 |
| Bromine worm Benzoylamide dimehypo | 1:1 | 0.43 | 235.41 |
| Bromine worm Benzoylamide dimehypo | 5:1 | 0.29 | 220.50 |
| Bromine worm Benzoylamide dimehypo | 15:1 | 0.27 | 212.39 |
| Bromine worm Benzoylamide dimehypo | 30:1 | 0.28 | 198.84 |
| Bromine worm Benzoylamide dimehypo | 40:1 | 0.31 | 178.25 |
| Bromine worm Benzoylamide dimehypo | 60:1 | 0.33 | 166.18 |
nullAs shown in Table 13，Bromine worm Benzoylamide and dimehypo compound the proportioning of preventing and treating Oryza sativa L. rice leaf roller when 1 80 ~ 60 1，Co-toxicity coefficient is all higher than 120，Illustrate that both all show potentiation at mixture in the range of 1 80 ~ 60 1，When the proportioning of bromine worm Benzoylamide and dimehypo is 1 40 ~ 51，Potentiation is the most prominent，Co-toxicity coefficient is all higher than 220，Test through applicant and find that bromine worm Benzoylamide is 5:1 with the optimum ratio of dimehypo、1:1、1:5、1:6、1:7、1:8、1:9、1:10、1:11、1:12、1:13、1:14、1:15、1:16、1:17、1:18、1:19、1:20、1:21、1:22、1:23、1:24、1:25、1:30、1、1:35、1:40，Wherein when bromine worm Benzoylamide and dimehypo weight ratio are 1 15, co-toxicity coefficient is maximum，Potentiation is the most obvious.
Application Example four
For examination insect: brassicaceous vegetable diamondback moth
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine bromine worm Benzoylamide and the former medicine of Cupric sulfate and effective lethasl concentration scope of the two different ratio mixture through pilot study
Table 14 bromine worm Benzoylamide toxicity test analysis of results table to brassicaceous vegetable diamondback moth compounding with Cupric sulfate
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.67 | — |
| Cupric sulfate | — | 13.38 | — |
| Bromine worm Benzoylamide Cupric sulfate | 1:80 | 5.58 | 194.28 |
| Bromine worm Benzoylamide Cupric sulfate | 1:60 | 4.93 | 207.02 |
| Bromine worm Benzoylamide Cupric sulfate | 1:50 | 4.41 | 221.14 |
| Bromine worm Benzoylamide Cupric sulfate | 1:40 | 3.96 | 231.00 |
| Bromine worm Benzoylamide Cupric sulfate | 1:30 | 3.42 | 242.71 |
| Bromine worm Benzoylamide Cupric sulfate | 1:20 | 2.76 | 254.70 |
| Bromine worm Benzoylamide Cupric sulfate | 1:10 | 2.02 | 243.11 |
| Bromine worm Benzoylamide Cupric sulfate | 1:5 | 1.38 | 232.97 |
| Bromine worm Benzoylamide Cupric sulfate | 1:1 | 0.58 | 220.02 |
| Bromine worm Benzoylamide Cupric sulfate | 10:1 | 0.35 | 209.52 |
| Bromine worm Benzoylamide Cupric sulfate | 20:1 | 0.35 | 200.50 |
| Bromine worm Benzoylamide Cupric sulfate | 40:1 | 0.36 | 190.53 |
| Bromine worm Benzoylamide Cupric sulfate | 60:1 | 0.38 | 179.10 |
nullAs shown in Table 14，Bromine worm Benzoylamide and Cupric sulfate compound the proportioning of preventing and treating brassicaceous vegetable diamondback moth when 1 80 ~ 60 1，Co-toxicity coefficient is all higher than 120，Illustrate that both all show potentiation at mixture in the range of 1 80 ~ 60 1，When the proportioning of bromine worm Benzoylamide and Cupric sulfate is 1 50 ~ 11，Potentiation is the most prominent，Co-toxicity coefficient is all higher than 220，Test through applicant and find that bromine worm Benzoylamide is 1:1 with the optimum ratio of Cupric sulfate、1:5、1:6、1:7、1:8、1:9、1:10、1:11、1:12、1:13、1:14、1:15、1:16、1:17、1:18、1:19、1:20、1:21、1:22、1:23、1:24、1:25、1:30、1、1:35、1:40、1:45、1:50，Wherein when bromine worm Benzoylamide and Cupric sulfate weight ratio are 1 20, co-toxicity coefficient is maximum，Potentiation is the most obvious.
Find through test: after bromine worm Benzoylamide is compounding with active component B, the striped rice borer in various crop, yellow rice borer, rice leaf roller, thrips, leafhopper, pachydiplosis oryzae, plant hopper, aphid, caterpillar, leaf miner, beet armyworm, diamondback moth, Pieris rapae, the preventing and treating of tea geometrid being had obvious potentiation, co-toxicity coefficient is all more than 120.
Application Example pentabromo-worm Benzoylamide and active component B and the compounding preventing and treating brassicaceous vegetable diamondback moth test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided, comparison medicament 10% bromine worm Benzoylamide suspending agent (autogamy), 50% thiocyclam soluble powder (commercial), 20% dimehypo water solution (commercial), 50% Cupric sulfate soluble powder (commercial).
Investigate brassicaceous vegetable diamondback moth insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 3 days, 7 days, 15 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 15 bromine worm Benzoylamide and active component B and the compounding preventing and treating brassicaceous vegetable diamondback moth test of pesticide effectiveness thereof
As can be seen from Table 15, can effectively prevent and treat brassicaceous vegetable diamondback moth after bromine worm Benzoylamide is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example hexabromo worm Benzoylamide and active component B and the compounding preventing and treating water rice hopper test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided, comparison medicament 10% bromine worm Benzoylamide suspending agent (autogamy), 50% thiocyclam soluble powder (commercial), 20% dimehypo water solution (commercial), 50% Cupric sulfate soluble powder (commercial).
Investigate water rice hopper insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 3 days, 7 days, 15 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 16 bromine worm Benzoylamide and active component B and the compounding preventing and treating water rice hopper test of pesticide effectiveness thereof
As can be seen from Table 16, can effectively prevent and treat water rice hopper after bromine worm Benzoylamide is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example seven bromine worm Benzoylamide and active component B and the compounding preventing and treating phyllocnistis citrella stainton test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided, comparison medicament 10% bromine worm Benzoylamide suspending agent (autogamy), 50% thiocyclam soluble powder (commercial), 20% dimehypo water solution (commercial), 50% Cupric sulfate soluble powder (commercial).
Investigate phyllocnistis citrella stainton insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 3 days, 7 days, 15 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 17 bromine worm Benzoylamide and active component B and the compounding preventing and treating phyllocnistis citrella stainton test of pesticide effectiveness thereof
As can be seen from Table 17, can effectively prevent and treat phyllocnistis citrella stainton after bromine worm Benzoylamide is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight bromine worm Benzoylamide and active component B and the compounding preventing and treating rice leaf roller test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided, comparison medicament 10% bromine worm Benzoylamide suspending agent (autogamy), 50% thiocyclam soluble powder (commercial), 20% dimehypo water solution (commercial), 50% Cupric sulfate soluble powder (commercial).
Investigate rice leaf roller insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 3 days, 7 days, 15 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 18 bromine worm Benzoylamide and active component B and the compounding preventing and treating rice leaf roller test of pesticide effectiveness thereof
As can be seen from Table 18, can effectively prevent and treat rice leaf roller after bromine worm Benzoylamide is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine bromine worm Benzoylamide and active component B and the compounding preventing and treating cabbage pieris test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided, comparison medicament 10% bromine worm Benzoylamide suspending agent (autogamy), 50% thiocyclam soluble powder (commercial), 20% dimehypo water solution (commercial), 50% Cupric sulfate soluble powder (commercial).
Investigate cabbage pieris insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 3 days, 7 days, 15 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 19 bromine worm Benzoylamide and active component B and the compounding preventing and treating cabbage pieris test of pesticide effectiveness thereof
As can be seen from Table 19, can effectively prevent and treat cabbage pieris after bromine worm Benzoylamide is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, after bromine worm Benzoylamide and thiocyclam, dimehypo, Cupric sulfate are compounding to the preventive effect of the common insect pests such as the striped rice borer in various crop, yellow rice borer, rice leaf roller, thrips, leafhopper, pachydiplosis oryzae, plant hopper, aphid, red spider, caterpillar, leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea geometrid all more than 95%, being better than single dose preventive effect, potentiation is obvious.
Claims (6)
1. a brominated worm Benzoylamide and the Pesticidal combination of neires toxin, effective active composition is active components A and active component B, it is characterized in that: active components A is 1 80 ~ 60 1 with the weight ratio of active component B, described active components A is bromine worm Benzoylamide, and active component B plants selected from one of thiocyclam, dimehypo, Cupric sulfate.
Brominated worm Benzoylamide the most according to claim 1 and the Pesticidal combination of neires toxin, it is characterised in that: active components A is 1 60 ~ 40 1 with the weight ratio of active component B.
Brominated worm Benzoylamide the most according to claim 2 and the Pesticidal combination of neires toxin, it is characterised in that:
Bromine worm Benzoylamide is 1 40 ~ 51 with the weight ratio of thiocyclam；
Bromine worm Benzoylamide is 1 40 ~ 51 with the weight ratio of dimehypo；
Bromine worm Benzoylamide is 1 50 ~ 11 with the weight ratio of Cupric sulfate.
Brominated worm Benzoylamide the most according to any one of claim 1 to 3 and the Pesticidal combination of neires toxin, it is characterised in that: compositions makes soluble powder, wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, microcapsule suspending agent.
Brominated worm Benzoylamide the most according to claim 4 is used for preventing and treating the purposes of insect on crops with the Pesticidal combination of neires toxin.
Purposes the most according to claim 5, it is characterised in that: described insect is striped rice borer, yellow rice borer, rice leaf roller, thrips, leafhopper, pachydiplosis oryzae, plant hopper, aphid, caterpillar, leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea geometrid.
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| CN1678192A (en) * | 2001-08-13 | 2005-10-05 | 纳幕尔杜邦公司 | Arthropodicidal anthranilamides |
| CN1988803A (en) * | 2004-07-26 | 2007-06-27 | 杜邦公司 | Mixtures of anthranilamide invertebrate pest control agents |
| CN101268779A (en) * | 2008-05-08 | 2008-09-24 | 国家农药创制工程技术研究中心 | Insecticidal composition containing chlorantraniliprole and monosultap |
| CN102113516A (en) * | 2010-01-05 | 2011-07-06 | 海南正业中农高科股份有限公司 | Insect killing compound containing chlorantraniliprole |
| CN102388892A (en) * | 2011-10-31 | 2012-03-28 | 湖南化工研究院 | Pesticide composition containing chlorantraniliprole and thiocyclam |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1678192A (en) * | 2001-08-13 | 2005-10-05 | 纳幕尔杜邦公司 | Arthropodicidal anthranilamides |
| CN1988803A (en) * | 2004-07-26 | 2007-06-27 | 杜邦公司 | Mixtures of anthranilamide invertebrate pest control agents |
| CN101268779A (en) * | 2008-05-08 | 2008-09-24 | 国家农药创制工程技术研究中心 | Insecticidal composition containing chlorantraniliprole and monosultap |
| CN102113516A (en) * | 2010-01-05 | 2011-07-06 | 海南正业中农高科股份有限公司 | Insect killing compound containing chlorantraniliprole |
| CN102388892A (en) * | 2011-10-31 | 2012-03-28 | 湖南化工研究院 | Pesticide composition containing chlorantraniliprole and thiocyclam |
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