CN103816087A - Whitening, sun-resistant and spot removing cosmetic of traditional Chinese medicine composition, and preparation method thereof - Google Patents
Whitening, sun-resistant and spot removing cosmetic of traditional Chinese medicine composition, and preparation method thereof Download PDFInfo
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- CN103816087A CN103816087A CN201410078654.6A CN201410078654A CN103816087A CN 103816087 A CN103816087 A CN 103816087A CN 201410078654 A CN201410078654 A CN 201410078654A CN 103816087 A CN103816087 A CN 103816087A
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Abstract
The invention relates to a whitening, sun-proof and spot removing cosmetic of traditional Chinese medicine composition, and a preparation method thereof, and belongs to the field of daily cosmetics. The whitening, sun-proof and spot removing cosmetic of the traditional Chinese medicine composition comprises the following bulk drugs in parts by weight: 1-12 parts of ginseng, 1-15 parts of angelica dahurica, 1-15 parts of liquorice and 1-15 parts of Chinese angelica. The invention has the following benefits: thetraditional Chinese medicine composition is applied to cosmetics, integrates multiple functions into a whole, and has the beauty functions of whitening, sun resisting, spot removing and diminishing inflammation. The cosmetic of traditional Chinese medicine composition comprises pure natural traditional Chinese medicine extracted compositions, so the cosmetic is safe, free from negative side effects and particularly has an obvious effect on allergic skin.
Description
Technical field
The invention belongs to daily cosmetics field, specially refer to a kind of cosmetics Chinese medicine composition with whitening, sun-proof, many effects of speckle dispelling.
Background technology
Cosmetics have very strong epochal character and trend as a kind of special article of everyday use, and the growing material and culture of its purchasing power and people requires closely related.In recent years, along with the appearance of natural component cosmetics, consumers in general hold more careful attitude for the safety of cosmetics, under the large situation of this naturalization of Cosmetic Manufacture raw material, the cosmetics of a feast for the eyes natural component arise at the historic moment, and cosmetic field has formed the worldwide upsurge of exploitation natural resources.
Chinese medicine natural product not only can directly improve in outside the state of skin, also can skin permeation, by improving structure and the material base of skin, by regulating, fundamentally improve the quality of skin inside.So, from natural plants, find whitening and speckle dispelling safely and effectively, moisturizing and nourishing, sun-proofly preserves youthful looks, the active substance of the anti-ageing effect of waiting for a long time become focus and the important directions of cosmetics research.
In the modern life, due to physiological function, external environment, the harmful effect of abusing cosmetics, there is clinically the skin problems such as face acne, skin sore, brown patch freckle, cutis laxa, dry decortication, the colour of skin are obscure, skin allergy in women.And commercially available whitening, sun-proof, speckle dispelling class cosmetics are not only also disputable in expensive and safety, and the many unification of effect take effect slowly, and with rear easy recurrence, make a lot of women too far behind to catch up, can whitening to cosmetics nor can meet women, again can speckle dispelling or the sun-proof desirable beauty treatment of many effects.
Summary of the invention
The invention provides a kind of cosmetics Chinese medicine composition and preparation method of whitening sun protection speckle dispelling, solve can not meet at present women can whitening to cosmetics, again can speckle dispelling or the problem of the sun-proof desirable beauty treatment of many effects.
The history of the existing more than one thousand years of Chinese medicine beauty treatment, of long standing and well established, theoretical abundant, method uniqueness, more and more receives people's favor and concern.
" Ling Shu Miraculous Pivot or Divine Axis pathogen cacosplanchnia shape ": " its vim and vigour all go up in face and walk sky key for the twelve regular channels, 365 networks.", scripture shows, people's complexion is relevant to QI and blood.In " General Treatise on the Cause and Symptoms of Diseases ", have: " dark complexion chap person, or internal organs have phlegm retention, or skin is subject to ailment said due to cold or exposure, all makes qi and blood disorder, and to raw black chap, the vital organs of the human body 12 menses, all go up in face, the trip of husband's blood, all flourish the exterior and the interior.People or phlegm retention waterlogging possession, or space between skin and muscles wind-engaging to vim and vigour get along well, puckery or turbid, can not be flourish in skin, it is raw black that side becomes." explanation of this section of scripture occurs that at face the disease such as speckle, rash is also relevant to phlegm retention, body constitution, internal organs.
The sweet temperature of Radix Ginseng, enters taste, as " king of BAICAO ", can strongly invigorating primordial QI, and nourishing blood to promote the production of body fluid, Fructus Alpiniae Oxyphyllae with fixed attention, is the monarch drug in side; The pungent temperature of the Radix Angelicae Dahuricae, enters lung, stomach warp, and function is delivered loose wind, reducing swelling and alleviating pain; In Shennong's Herbal, squeezing carrying it can " longue skin, moist color, can do face fat " be ministerial drug; Chinese Angelica blood replonishing is invigorated blood circulation, and promoting the circulation of blood blood stasis dispelling is adjuvant drug; Radix Glycyrrhizae property is flat, and coordinating the actions of various ingredients in a prescription, for making medicine, is taken a broad view of full side, plays altogether QI invigorating deliver, nourish blood effect of detumescence.
Drug component of the present invention is according to theory of Chinese medical science, and its consumption is also groped in a large number to sum up through inventor and drawn, each amounts of components for all having better effect within the scope of following weight:
1～12 part of Radix Ginseng, 1～15 part of the Radix Angelicae Dahuricae, 1～15 part, Radix Glycyrrhizae, 1～15 part of Radix Angelicae Sinensis;
Radix Ginseng used can use Radix Panacis Quinquefolii, Radix Codonopsis, Radix Ginseng Rubra, Korean Ginseng or Radix Pseudostellariae to replace:
In described side, also comprise wherein one or more of the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae with whitening effect, its weight portion is: 1～15 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1～15 part of the Radix Paeoniae Alba, 1～15 part of the Rhizoma Atractylodis Macrocephalae;
The sweet temperature of Radix Ginseng, enters taste, as " king of BAICAO ", can strongly invigorating primordial QI, and nourishing blood to promote the production of body fluid, Fructus Alpiniae Oxyphyllae with fixed attention, is the monarch drug in side; The pungent temperature of the Radix Angelicae Dahuricae, enters lung, stomach warp, and function is delivered loose wind, reducing swelling and alleviating pain.In Shennong's Herbal, squeeze carry it can " longue skin, moist color, can do face fat "; The Pseudobulbus Bletillae (Rhizoma Bletillae) is pungent, bitter, be slightly cold, and enters lung, stomach, kidney channel, has removing stasis to stop bleeding, the effect of tonifying the lung granulation promoting.It " controls " property of medicine opinion " cloud skin ulcer on face, makes us flesh and slide ", and it " washes one's face Compendium of Material Medica cloud black, speckle dispelling "; The Radix Paeoniae Alba, sweet in the mouth is flat, nontoxic, YIN nourishing and the production of body fluid promoting, records that " cure mainly the five internal organs pathogen; anemofrigid-damp arthralgia, invigorating the spleen and replenishing QI, controls the heart outstanding; few food is normal hungry, and clothes are made light of one's life by commiting suicide for a long time, normal hearing and eyesight; the upper three medicines wind that falls apart nourishes blood; promoting blood circulation and detumescence granulation promoting is ministerial drug, and Chinese Angelica blood replonishing is invigorated blood circulation, and Rhizoma Atractylodis Macrocephalae invigorating the spleen to clear away damp pathogen is the adjuvant drug in the side of being altogether in " General Treatise on the Cause and Symptoms of Diseases ".Radix Glycyrrhizae property is flat, and coordinating the actions of various ingredients in a prescription, for making medicine, is taken a broad view of full side, plays benefiting QI and nourishing blood altogether, lung heat clearing expels the heat-evil, effect of promoting blood circulation to restore menstrual flow, speckle dispelling.
In described side, also comprise there is sun-proof function Radix Scutellariae, the Radix Astragali, Folium Ginkgo wherein one or more, its weight portion is: 1～15 part of Radix Scutellariae, 1～15 part of the Radix Astragali, 1～15 part of Folium Ginkgo.
The sweet temperature of Radix Ginseng, enters taste, as " king of BAICAO ", can strongly invigorating primordial QI, and nourishing blood to promote the production of body fluid, Fructus Alpiniae Oxyphyllae with fixed attention, is the monarch drug in side, and the pungent temperature of the Radix Angelicae Dahuricae, enters lung, stomach warp, and function is delivered loose wind, reducing swelling and alleviating pain.In Shennong's Herbal, squeeze carry it can " longue skin, moist color, can do face fat "; The Pseudobulbus Bletillae (Rhizoma Bletillae) is pungent, bitter, be slightly cold, and enters lung, stomach, kidney channel, has removing stasis to stop bleeding, the effect of tonifying the lung granulation promoting.It " controls " property of medicine opinion " cloud skin ulcer on face, makes us flesh and slide ", and it " washes one's face Compendium of Material Medica cloud black, speckle dispelling "; The Radix Paeoniae Alba, sweet in the mouth, flat, nontoxic, YIN nourishing and the production of body fluid promoting, in " General Treatise on the Cause and Symptoms of Diseases ", record " cure mainly the five internal organs pathogen; anemofrigid-damp arthralgia, invigorating the spleen and replenishing QI, becomes mildewed that it is black to issue an order, and controls the heart outstanding, and few food is normal hungry; clothes are made light of one's life by commiting suicide for a long time, normal hearing and eyesight, and the upper three medicines wind that falls apart nourishes blood, and promoting blood circulation and detumescence granulation promoting is ministerial drug, and Chinese Angelica blood replonishing is invigorated blood circulation; Radix Astragali replenishing QI to invigorate the spleen; Folium Ginkgo promoting blood circulation and stopping pain; The clear eliminating the pathogens from the lung heat of Radix Scutellariae, Rhizoma Atractylodis Macrocephalae invigorating spleen to remove dampness, it is altogether the adjuvant drug in side that the above five tastes get rid of evils that righting takes into account, and Radix Glycyrrhizae property is flat, and coordinating the actions of various ingredients in a prescription, for making medicine, is taken a broad view of full side, plays altogether benefiting QI and nourishing blood, lung heat clearing expels the heat-evil, the effect of the promoting blood circulation to restore menstrual flow.
Cosmetics Chinese medicine composition of the present invention active ingredient can adopt the conventional method of Chinese medicine preparation to be prepared into the preparation of any exterior-applied formulation.Preferably, the preparation method of medicine activity component of the present invention is as follows:
Get the Radix Ginseng in formula, add 6～20 times of water gagings, percolation 2～9 hours, repeats 1～3 time, merging filtrate, then add 6～15 times to measure 40～95% ethanol, and ultrasonic 2～3 times, frequency 100Hz, each time 10～30min, merges above-mentioned filtrate, is concentrated into clear paste; All the other medical materials add 6～20 times of water gagings and reflux 2～3 times, and each 2～6 hours, merging filtrate, then add 5～10 times to measure 40～95% ethanol, and extract 2～3 times, each 1～5 hour, merge above-mentioned filtrate, be concentrated into clear paste.
Wherein, the backflow of Radix Ginseng percolation or all the other medical materials can equivalence replace with supercritical extraction or infusion process or circumfluence method or ultrasonic method or dipping-ultrasonic method.
Invention cosmetics Chinese medicine composition of the present invention active ingredient can be prepared into any type of cosmetics according to a conventional method with the conventional adjuvant of preparing cosmetics, and the conventional adjuvant of cosmetics comprises surfactant, the materials such as oils and fats; Described surfactant is selected from polyoxyethylene hydrogenated Oleum Ricini, polyoxyethylene fatty acid ester, and polyoxyethylene aliphatic alcohol ether, fatty acid Pyrusussuriensis is smooth etc.; Described oils and fats is selected from vegetable oil, animal wet goods; Also comprise vitamin and derivant thereof, hyaluronic acid, wetting agent, chelating agen, pH adjusting agent, excipient, antiseptic, one or more of aromatic.
In the present invention, each raw medicinal material complements each other, and external is infiltrated rapidly in skin effective ingredient, directly decomposes desalination melanin, remove free radical, antioxidation and restraint of tyrosinase, refinement pachylosis composition, dredge the pore that is obstructed, meanwhile, can also strengthen the immunologic function of cell.Thereby reach the object of whitening, sun-proof, speckle dispelling.
The invention has the beneficial effects as follows:
1. inherit and developed Culture of TCM, use multiple medicinal and edible plant, in conjunction with traditional Chinese medical science compatibility theory, make its photodamage resistant effect, whitening function, anti-sunlight function, effect of dispelling spots remarkably productive, the characteristic of unique formula and the unification of multiple beauty functions, has filled up at present the blank in this field both at home and abroad.
The present invention be applied in cosmetics, there is moisturizing whitening simultaneously, the beautification function of many effects unifications of sun-proof, speckle dispelling antiinflammatory.
3. in the present invention, comprised natural Chinese medicines and extracted compositions, safely, have no side effect, especially to allergic skin successful.
4. the present invention in conjunction with modern transdermal drag delivery novel form etc., makes various effective ingredient see through cutin barrier, directly acts on each layer of skin, reaches directed Transdermal absorption.
The specific embodiment
Embodiment 1
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis.
Preparation method: get the Radix Ginseng in formula, add 6 times of water gagings, percolation 2 hours, 1 time, then add 6 times to measure 40% ethanol, and ultrasonic 2 times, frequency 100Hz, each time 10min, merges above-mentioned filtrate, is concentrated into clear paste; All the other medical materials add 6 times of water gagings and reflux 2 times, and each 2 hours, merging filtrate, then add 5 times to measure 40% ethanol, and extract 2 times, each 1 hour, merge above-mentioned filtrate, be concentrated into clear paste.
Embodiment 2
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis;
Preparation method: get the Radix Ginseng in formula, add 13 times of water gagings, percolation 5.5 hours, repeats 2 times, merging filtrate, then add 10.5 times to measure 65% ethanol, and ultrasonic 3 times, frequency 100Hz, each time 20min, merges above-mentioned filtrate, is concentrated into clear paste; All the other medical materials add 13 times of water gagings and reflux 3 times, and each 4 hours, merging filtrate, then add 7.5 times to measure 65% ethanol, and extract 3 times, each 3 hours, merge above-mentioned filtrate, be concentrated into clear paste.
Embodiment 3
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis;
Preparation method: get the Radix Ginseng in formula, add 20 times of water gagings, percolation 9 hours, repeats 3 times, merging filtrate, then add 15 times to measure 95% ethanol, and ultrasonic 3 times, frequency 100Hz, each time 30min, merges above-mentioned filtrate, is concentrated into clear paste; All the other medical materials add 20 times of water gagings and reflux 3 times, and each 6 hours, merging filtrate, then add 10 times to measure 95% ethanol, and extract 3 times, each 5 hours, merge above-mentioned filtrate, be concentrated into clear paste.
Embodiment 4
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Pseudobulbus Bletillae (Rhizoma Bletillae).
Embodiment 5
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Radix Paeoniae Alba.
Embodiment 6
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Rhizoma Atractylodis Macrocephalae.
Embodiment 7
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of the Radix Paeoniae Alba.
Embodiment 8
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of the Rhizoma Atractylodis Macrocephalae.
Embodiment 9
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Radix Paeoniae Alba, 1 part of the Rhizoma Atractylodis Macrocephalae.
Embodiment 10
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of the Radix Paeoniae Alba, 1 part of the Rhizoma Atractylodis Macrocephalae.
Embodiment 11
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
Embodiment 12
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Radix Paeoniae Albas.
Embodiment 13
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 14
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 8 parts of the Radix Paeoniae Albas.
Embodiment 15
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 8 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 16
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Radix Paeoniae Albas, 8 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 17
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 8 parts of the Radix Paeoniae Albas, 8 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 18
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
Embodiment 19
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas.
Embodiment 20
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 21
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Radix Paeoniae Albas.
Embodiment 22
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 23
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas, 15 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 24
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of the Radix Paeoniae Albas, 15 parts of the Rhizoma Atractylodis Macrocephalaes.
Embodiment 25
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of Radix Scutellariae.
Embodiment 26
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Radix Astragali.
Embodiment 27
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of Folium Ginkgo.
Embodiment 28
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of Radix Scutellariae, 1 part of the Radix Astragali.
Embodiment 29
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of Radix Scutellariae, 1 part of Folium Ginkgo.
Embodiment 30
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of the Radix Astragali, 1 part of Folium Ginkgo.
Embodiment 31
1 part of Radix Ginseng, 1 part of the Radix Angelicae Dahuricae, 1 part, Radix Glycyrrhizae, 1 part of Radix Angelicae Sinensis, 1 part of Radix Scutellariae, 1 part of the Radix Astragali, 1 part of Folium Ginkgo.
Embodiment 32
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Scutellariaes.
Embodiment 33
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Radixs Astragali.
Embodiment 34
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of Folium Ginkgos.
Embodiment 35
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Scutellariaes, 8 parts of the Radixs Astragali.
Embodiment 36
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Scutellariaes, 8 parts of Folium Ginkgos.
Embodiment 37
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of the Radixs Astragali, 8 parts of Folium Ginkgos.
Embodiment 38
6.5 parts of Radix Ginsengs, 8 parts of the Radixs Angelicae Dahuricae, 8 parts, Radix Glycyrrhizae, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Scutellariaes, 8 parts of the Radixs Astragali, 8 parts of Folium Ginkgos.
Embodiment 39
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Scutellariaes.
Embodiment 40
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali.
Embodiment 41
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of Folium Ginkgos.
Embodiment 42
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Scutellariaes, 15 parts of the Radixs Astragali.
Embodiment 43
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Scutellariaes, 15 parts of Folium Ginkgos.
Embodiment 44
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 15 parts of Folium Ginkgos.
Embodiment 45
12 parts of Radix Ginsengs, 15 parts of the Radixs Angelicae Dahuricae, 15 parts, Radix Glycyrrhizae, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Scutellariaes, 15 parts of the Radixs Astragali, 15 parts of Folium Ginkgos.
Embodiment 46～52
In embodiment 4～embodiment 10, add respectively 1 part of Radix Scutellariae.
Embodiment 53～59
In embodiment 4～embodiment 10, add respectively 1 part of the Radix Astragali.
Embodiment 60～66
In embodiment 4～embodiment 10, add respectively 1 part of Folium Ginkgo.
Embodiment 67～73
In embodiment 4～embodiment 10, add respectively 1 part of Radix Scutellariae, 1 part of the Radix Astragali.
Embodiment 74～80
In embodiment 4～embodiment 10, add respectively 1 part of Radix Scutellariae, 1 part of Folium Ginkgo.
Embodiment 81～87
In embodiment 4～embodiment 10, add respectively 1 part of the Radix Astragali, 1 part of Folium Ginkgo.
Embodiment 88～94
In embodiment 4～embodiment 10, add respectively 1 part of Radix Scutellariae, 1 part of the Radix Astragali, 1 part of Folium Ginkgo.
Embodiment 95～101
In embodiment 11～embodiment 17, add respectively 8 parts of Radix Scutellariaes.
Embodiment 102～108
In embodiment 11～embodiment 17, add respectively 8 parts of the Radixs Astragali.
Embodiment 108～114
In embodiment 11～embodiment 17, add respectively 8 parts of Folium Ginkgos.
Embodiment 115～121
In embodiment 11～embodiment 17, add respectively 8 parts of Radix Scutellariaes, 8 parts of the Radixs Astragali.
Embodiment 122～128
In embodiment 11～embodiment 17, add respectively 8 parts of Radix Scutellariaes, 8 parts of Folium Ginkgos.
Embodiment 129～135
In embodiment 11～embodiment 17, add respectively 8 parts of Radix Scutellariaes, 8 parts of the Radixs Astragali, 8 parts of Folium Ginkgos.
Embodiment 136～142
In embodiment 18～embodiment 24, add respectively 15 parts of Radix Scutellariaes.
Embodiment 143～149
In embodiment 18～embodiment 24, add respectively 15 parts of the Radixs Astragali.
Embodiment 150～156
In embodiment 18～embodiment 24, add respectively 15 parts of Folium Ginkgos.
Embodiment 157～163
In embodiment 18～embodiment 24, add respectively 15 parts of Radix Scutellariaes, 15 parts of the Radixs Astragali.
Embodiment 164～170
In embodiment 18～embodiment 24, add respectively 15 parts of Radix Scutellariaes, 15 parts of Folium Ginkgos.
Embodiment 171～177
In embodiment 18～embodiment 24, add respectively 15 parts of the Radixs Astragali, 15 parts of Folium Ginkgos.
Embodiment 178～184
In embodiment 18～embodiment 24, add respectively 15 parts of Radix Scutellariaes, 15 parts of the Radixs Astragali, 15 parts of Folium Ginkgos.
In above-mentioned all embodiment, Radix Ginseng can use Radix Panacis Quinquefolii, Radix Codonopsis, Radix Ginseng Rubra, Korean Ginseng or Radix Pseudostellariae to replace.
Described preparation method, the backflow of Radix Ginseng percolation or all the other medical materials can equivalence replace with supercritical extraction or infusion process or circumfluence method or ultrasonic method or dipping-ultrasonic method.
Application examples Chinese medicine composition cosmetics of the present invention emulsifiable paste
The accurate conventional adjuvant of preparing emulsifiable paste, glycerol, Polysorbate, the Semen pruni armeniacae oil of taking respectively, span, deionized water, essence, the Effective Component of Chinese Medicine of antiseptic and the various embodiments described above etc., also constantly be stirred to and mix in different vessel in heating, when temperature is down to room temperature, bottling.
Experimental example cosmetics white-skinned face function experiment of the present invention
Be prepared into respectively many effects Chinese medicine composition cosmetics with the Effective Component of Chinese Medicine of the various embodiments described above.It is 100mg/mL that the phosphate buffer (PBS) of pH=6.8 is prepared into concentration, in 4 ℃ of refrigerators, saves backup.
TYR enzymatic solution: face used time PBS(pH6.8) preparation, concentration 10 μ g/mL; L-Dopa solution: face used time PBS(pH6.8) preparation, mass fraction is 0.05%; Arbutin matched group solution: accurately weighed arbutin, adds PBS(pH6.8) be mixed with 15.00mg/mL, for subsequent use.
Method: A1 test specimens: 2mLPBS+1mL TYR enzymatic solution; A2 test specimens: 3mLPBS; A3 test specimens: 1mL sample solution+1mLPBS+1mL TYR enzymatic solution; A4 test specimens: 1mL sample solution+2mLPBS.
Establish parallel 3 groups of test tubes for every group, first put in 25 water-baths and be incubated after 10min, add respectively immediately L-Dopa solution 1mL, mix homogeneously.React 2min with 25 ℃ of constant temperature water baths and measure immediately absorbance at 475nm place.
TYR inhibition of enzyme activity rate (%)=[(A1-A2)-(A3-A4)]/(A1-A2) × 100
Results and analysis
By every group of parallel repetition of above-mentioned test method 3 times, OD value is added and averages.Press TYR inhibition of enzyme activity rate formula and calculate, the results are shown in following table 1.
The suppression ratio (X ± S, n=3) of many effects Chinese medicine composition breast of the different prescriptions of table 1 the present invention to TYR enzyme
Experimental result demonstration, it is all eager to excel many effects Chinese medicine composition of preparing by relevant embodiment breast than arbutin to the suppression ratio of TYR enzyme, has significant difference (P ﹤ 0.05).Illustrate that the present invention has stronger white-skinned face function.
Experimental example sun-proof function experiment of the present invention
The breast cosmetics that above-described embodiment is prepared carries out sun-proof function experiment, according to sun-proof Performance Evaluating Indexes Boots star representation, the results are shown in Table 2.
The comparison of the anti-Sai effect of table 2. the present invention and reference substance
Known according to table, this invention and reference substance all have anti-sunlight function, and this invention sun-proof result is better than reference substance.
Experimental example cosmetics spot-removal function of the present invention Journal of Sex Research
Experimental subject: 650 of the volunteers that the age is 20～45, be divided into 13 groups, wherein every group of male is 10.Their feature is: chloasma, sun speckle, butterfly spot, freckle, withered and yellow black face etc.
Method: 1～12 volunteer of group uses respectively the Emulsion of the Chinese medicine composition of above-described embodiment 1,2,3,10,17,24,31,38,45,94,135,184 every morning, and smear evening with the essence of many effect cosmetics Chinese medicine composition of different prescriptions; 28 days time.
13 volunteer every days of group are sooner or later with cosmetics common on market, 28 days time.
Experimental result is in table 3:
Table 3 cosmetics spot-removal function of the present invention interpretation table
Experimental result shows that the total effective rate of 28 days each groups is respectively 90%, 100%, 100%, 90%, 90%, 100%, 90%, 100%, 90%, 100%, 100%, 100%, 26%; The cure rate of each group is respectively 90%, 92%, 94%, 88%, 90%, 94%, 92%, 94%, 94%, 94%, 96%, 96%, 8%.To volunteer with not finding mottle rebound phenomena in rear trimestral observation.The present invention is simultaneously at skin moisture-keeping, and delicate skin aspect also plays good result.In experiment, also find, product of the present invention also has 80% desalination effect to black eye, wrinkle.
Experimental example cosmetics safety Journal of Sex Research of the present invention
Cosmetics of the present invention belong to external preparation, and it is carried out to safety research.Adopt the Chinese medicine composition cosmetics emulsifiable paste in application examples.
Tested rabbit is fixed in rabbit fixed bin, is applied on the plucked skin in right side with this given the test agent 0.5g, application area is (2.5 × 2.5) cm
2, smear every day once, smear continuously 14d.Since the 2nd day, before smearing, answer cropping at every turn, remove residual sample with warm water, observed result after 1h, check plot, left side is smeared 0.5mL normal saline and is contrasted, by the scoring of skin irritation reaction standards of grading, calculate every tested rabbit integral mean value every day, judge skin stimulus intensity.Experimental result shows: all, without red and swollen, fester in animal subject back, blister phenomenon, is as good as with blank group skin, shows product nonirritant of the present invention, safe and reliable.
Effect:
Adopt the natural cosmetics that the present composition is prepared to be applicable to various crowds' uses, particularly to ultraviolet allergy, face acne, skin sore brown patch, pachylosis, the crowd that the colour of skin is obscure, that one has whitening, sun-proof, the multi-functional cosmetics such as light speckle, on formula, not only consider to have the plant of anti-thermal effect, also choose and there is whitening granulation promoting, slow down aging, light speckle antiinflammatory, promote the plant of the functions such as skin cell metabolism, assist a ruler in governing a country the conventional adjuvant of the cosmetics that have no side effect, in conjunction with modern transdermal drag delivery novel form etc., make each effective ingredient see through stratum corneum barrier, directly act on each layer of skin, reach directed Transdermal absorption, make cytothesis, help to recover impaired skin, whitening and moistening skin, speckle dispelling antiinflammatory, remove free radical, reduce ultraviolet, the injury of face acne to skin, and energy bright color, strengthen skin elasticity, skin is compacted.
Claims (8)
1. a cosmetics Chinese medicine composition for whitening sun protection speckle dispelling, is characterized in that comprising the crude drug of following weight portion:
1～12 part of Radix Ginseng, 1～15 part of the Radix Angelicae Dahuricae, 1～15 part, Radix Glycyrrhizae, 1～15 part of Radix Angelicae Sinensis.
2. the cosmetics Chinese medicine composition of whitening sun protection speckle dispelling according to claim 1, characterized by further comprising one or more in the crude drug of following weight portion;
1～15 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1～15 part of the Radix Paeoniae Alba, 1～15 part of the Rhizoma Atractylodis Macrocephalae.
3. the cosmetics Chinese medicine composition of whitening sun protection speckle dispelling according to claim 1 and 2, characterized by further comprising one or more in the crude drug of following weight portion;
1～15 part of Radix Scutellariae, 1～15 part of the Radix Astragali, 1～15 part of Folium Ginkgo.
4. the cosmetics Chinese medicine composition of whitening sun protection speckle dispelling according to claim 1 and 2, is characterized in that Radix Ginseng used can use Radix Panacis Quinquefolii, Radix Codonopsis, Radix Ginseng Rubra, Korean Ginseng or Radix Pseudostellariae to replace.
5. the cosmetics Chinese medicine composition of whitening sun protection speckle dispelling according to claim 3, is characterized in that Radix Ginseng used can use Radix Panacis Quinquefolii, Radix Codonopsis, Radix Ginseng Rubra, Korean Ginseng or Radix Pseudostellariae to replace.
6. the preparation method of the cosmetics Chinese medicine composition of whitening sun protection speckle dispelling as claimed in claim 1 or 2, is characterized in that comprising the following steps:
Get the Radix Ginseng in formula, add 6～20 times of water gagings, percolation 2～9 hours, repeats 1～3 time, merging filtrate, then add 6～15 times to measure 40～95% ethanol, and ultrasonic 2～3 times, frequency 100Hz, each time 10～30min, merges above-mentioned filtrate, is concentrated into clear paste; All the other medical materials add 6～20 times of water gagings and reflux 2～3 times, and each 2～6 hours, merging filtrate, then add 5～10 times to measure 40～95% ethanol, and extract 2～3 times, each 1～5 hour, merge above-mentioned filtrate, be concentrated into clear paste.
7. the preparation method of the cosmetics Chinese medicine composition of whitening sun protection speckle dispelling as claimed in claim 3, is characterized in that comprising the following steps:
Get the Radix Ginseng in formula, add 6～20 times of water gagings, percolation 2～9 hours, repeats 1～3 time, merging filtrate, then add 6～15 times to measure 40～95% ethanol, and ultrasonic 2～3 times, frequency 100Hz, each time 10～30min, merges above-mentioned filtrate, is concentrated into clear paste; All the other medical materials add 6～20 times of water gagings and reflux 2～3 times, and each 2～6 hours, merging filtrate, then add 5～10 times to measure 40～95% ethanol, and extract 2～3 times, each 1～5 hour, merge above-mentioned filtrate, be concentrated into clear paste.
8. the preparation method of the cosmetics Chinese medicine composition of whitening sun protection speckle dispelling as claimed in claim 6, is characterized in that: the backflow of Radix Ginseng percolation or all the other medical materials can equivalence replace with supercritical extraction or infusion process or circumfluence method or ultrasonic method or dipping-ultrasonic method.
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Application publication date: 20140528 |